Contrast Material and CT Translational Research Lab

Mission Statement: To develop and validate new CT techniques and develop novel contrast agents to dramatically improve patient diagnoses, presurgical planning, and treatment monitoring. 

Our translational research group, led by Benjamin Yeh, MD, focuses on the exploration and development of novel CT techniques, including dual energy CT and novel contrast enhanced imaging, for the diagnosis of clinical disease. Our preclinical work involves validating and testing the limits of CT scanning in both phantom and preclinical models, and includes the development and testing of  CT contrast materials. Our clinical research involves retrospective and prospective assessment of the value of contrast enhanced imaging for clinical use. Our facilities include a 1,080 square foot chemistry lab conveniently located near preclinical labs and clinical scanners.

Our Research

Our research group has been continuously funded by the NIH since 2007 and works closely with the abdominal imaging subspecialty of the UCSF Department of Radiology and Biomedical Imaging. Lab members include international visiting radiologists and students from the UCSF Medical School, Masters in Biomedical Imaging, and Masters in Translational Imaging.

People

Director

Lab Manager

  • Yuxin Sun, MS

Trainees:

  • Joshua Chen
  • Samuel Shu
  • Sergio Grosu, MD
  • Markus Obmann, MD

Visting Faculty:

  • Chansik An, MD
  • Wei-Chou Chang, MD
  • Hsuan-Hwai Lin, MD
  • Tingting Zhang, MD

Collaborators:

  • Bruce Johnson – General Electric Global Research Center
  • Paul Fitzgerald – General Electric Global Research Center
  • Peter Edic, PhD – General Electric Global Research Center
  • Jeannette Roberts  – General Electric Global Research Center
  • Amar Dhanantwari, PhD – Canon Healthcare
  • Zhen Jane Wang, MD – UCSF Dept. of Radiology
  • Antonio Westphalen, MD – UCSF Dept. of Radiology
  • Judy Yee, MD – Montefiore Dept. of Radiology
  • Spencer Behr, MD – UCSF Dept. of Radiology
  • Ronald Zagoria, MD – UCSF Dept of Radiology
  • Carol Stillson, MD – UCSF Dept of Radiology

Honors and Awards

  • 2019 - Certificate of Merit, Poster presentation: Recognizing Artifacts and Pitfalls of Multi-Energy CT. Parakh A, An C, Lennartz S, Yeh BM, Simeone FJ, Sahani DV, Kambadakone A. Radiological Society of North America, Chicago, IL
  • 2019 -  Certificate of Merit, Poster presentation: Dual-Energy CT of Acute Bowel Ischemia. Obmann M, Punjabi G, Winkel D, Boll D, Heye T, Yeh BM, Stieltjes B, Benz M. Radiological Society of North America, Chicago, IL
  • 2018 – Cum Laude, Scientific Poster Award: Differentiating common oral medications from iodinated contrast using dual energy CT; a multi-platform phantom study. Obmann MM, Ohliger MA, Sun Y, An C, Wang ZJ, Yeh BM. Society of Computed Tomography and Magnetic Resonance, Washington DC.
  • 2015 - Distinguished Investigator Award, Academy of Radiology Research.
    Top Doctor 2015-2017, Diagnostic radiology specialty. San Francisco Magazine
  • 2015 - UCSF Clinical and Translational Science Institute Catalyst Award, Top award for commercializable technology: Biphasic Enteric Contrast Material for CT. Co-awardee with Zhen Jane Wang, MD.
  • 2015 - Outstanding Medical Student Mentor Award. UCSF Dept of Radiology
  • 2014 - Cum Laude Award: Zhao L, Wang ZJ, Kim S, Wu E, Chang W, Lambert J, Yeh BM. Dual Energy CT of the Intestines: Pearls and Pitfalls. Poster presentation at the Radiological Society of North America, 2014
  • 2013 - UCSF Clinical and Translational Science Institute Catalyst Award, Spring 2013. Top award for commercializable technology: Enteric Dual Energy CT Contrast Material. Co-awardee with Yanjun Fu, PhD.
  • 2013 - Certificate of Merit: Miracle AC, Behr SC, Yeh BM. Vascular bowel injuries: A review of key findings and potential pitfalls. Scientific poster presented at the Radiological Society of North America, Chicago, IL. (Poster presentation)
  • 2011 - Magna Cum Laude Award: Liver Imaging Reporting and Data System (LI-RADS): An ACR-supported System for Classification of Hepatic Lesions on CT and MR Imaging in Patients with Cirrhosis. Santillan CS, Cruite IW, Yeh BM, Mitchell DG, Sirlin CB. (RSNA Poster presentation)
  • 2011 - Society of Gastrointestinal Radiologists Visiting Professsorship Award.

Research Directions

Our translational research group focuses on the exploration and development of novel CT techniques for the diagnosis of clinical disease. Our preclinical work involves validating and testing the limits of CT scanning in both phantom and animal models, and includes the development and testing of novel CT contrast materials.

Selected Funding

  • Nanoparticle CT Contrast Agent for New Capabilities in Tumor Detection, Staging, and Therapy Planning and Response
    NIH/NCI 1R01CA226868 May 1, 2019 - Apr 30, 2023
    Role: Joint-Principal Investigator
  • Spectral CT Imaging in the Abdomen
    Philips Healthcare. Oct 1, 2018 – Sept 30, 2021
    Role: Principal Investigator
  • MR Imaging of hepatocellular carcinoma in the cirrhotic patient
    Guerbet. July 1, 2020 – June 30, 2021
    Role: Principal Investigator
  • Augmenting Dual Energy CT for Novel Contrast Agents
    NIH/NIDDK R42DK104580 Sep 16, 2014 - Jul 31, 2020
    Role: Principal Investigator
  • Peritoneal cancer detection with positive versus neutral oral contrast.
    General Electric Healthcare Apr 1, 2019 – March 30, 2020.
    Role: Principal Investigator
  •  

Publications

Publications since 2012

  • Obmann MM, Cosentino A, Cyriac J, Hofmann V, Stieltjes B, Boll DT, Yeh BM, Benz MR. Quantitative enhancement thresholds and machine learning algorithms for the evaluation of renal lesions using single-phase split-filter dual-energy CT. Abdom Radiol (NY). 2019 Aug 26. [epub ahead of print]
  • Huang HC, Srinivasan R, Sun Y, Kazakia GJ, Lin PC, Yeh BM. Detection of Lumbar Spine Osseous Metastases Using Dual-Energy CT: Phantom Results and Preliminary Clinical Validation. AJR Am J Roentgenol. 2019 Feb;212(2):402-410. doi: 10.2214/AJR.18.19933
  • Winklhofer S, Lin WC, Wang ZJ, Behr SC, Westphalen AC, Yeh BM. Comparison of Positive Oral Contrast Agents for Abdominopelvic CT. AJR Am J Roentgenol. 2019 Mar 5:1-7. doi: 10.2214/AJR.18.20445. [Epub ahead of print]
  • Torphy RJ, Wang Z, True-Yasaki A, Volmar KE, Rashid N, Yeh B, Anderson JM, Johansen JS, Hollingsworth MA, Yeh JJ, Collisson EA. Stromal Content Is Correlated With Tissue Site, Contrast Retention, and Survival in Pancreatic Adenocarcinoma. JCO Precis Oncol. 2018;2018. doi: 10.1200/PO.17.00121. Epub 2018 Jan 16.
  • Jha P, Yeh BM, Zagoria R, Collisson E, Wang ZJ. The Role of MR Imaging in Pancreatic Cancer. Magn Reson Imaging Clin N Am. 2018 Aug;26(3):363-373.
  • Yeh BM, Obmann MM, Westphalen AC, Ohliger MA, Yee J, Sun Y, Wang ZJ. Dual Energy Computed Tomography Scans of the Bowel: Benefits, Pitfalls, and Future Directions. Radiol Clin North Am. 2018 Sep;56(5):805-819.
  • Wang ZJ, Behr S, Consunji MV, Yeh BM, Ohliger MA, Gao K, Ko AH, Cinar P, Tempero MA, Collisson EA. Early Response Assessment in Pancreatic Ductal Adenocarcinoma Through Integrated PET/MRI. AJR Am J Roentgenol. 2018 Jul 31:1-10
  • Lambert JW, Sun Y, Stillson C, Li Z, Kumar R, Wang S, FitzGerald PF, Bonitatibus PJ Jr, Colborn RE, Roberts JC, Edic PM, Marino M, Yeh BM. An Intravascular Tantalum Oxide-based CT Contrast Agent: Preclinical Evaluation Emulating Overweight and Obese Patient Size. Radiology. 2018 Oct;289(1):103-110.
  • Shah R, Khoram R, Lambert JW, Sun Y, Wang ZJ, Webb EM, Yeh BM. Effect of gantry rotation speed and scan mode on peristalsis motion artifact frequency and severity at abdominal CT. Abdom Radiol (NY). 2018 Feb 15
  • Cabarrus MC, Yeh BM, Phelps AS, Ou JJ, Behr SC. From Inguinal Hernias to Spermatic Cord Lipomas: Pearls, Pitfalls, and Mimics of Abdominal and Pelvic Hernias. Radiographics. 2017 Nov-Dec;37(7):2063-2082.
  • Fowler KJ, Tang A, Santillan C, Bhargavan-Chatfield M, Heiken J, Jha RC, Weinreb J, Hussain H, Mitchell DG, Bashir MR, Costa EAC, Cunha GM, Coombs L, Wolfson T, Gamst AC, Brancatelli G, Yeh B, Sirlin CB. Interreader Reliability of LI-RADS Version 2014 Algorithm and Imaging Features for Diagnosis of Hepatocellular Carcinoma: A Large International Multireader Study. Radiology. 2018 Jan;286(1): 173-185.
  • FitzGerald PF, Colborn RE, Edic PM, Lambert JW, Bonitatibus PJ Jr, Yeh BM. Liquid tissue surrogates for X-ray and CT phantom studies. Med Phys. 2017 Dec;44(12):6251-6260.
  • ​Lambert JW, Sun Y, Ordovas KG, Gould RG, Wang S, Yeh BM. Improved Calcium Scoring at Dual-Energy Computed Tomography Angiography Using a High-Z Contrast Element and Novel Material Separation Technique. J Comput Assist Tomogr. 2017 Sep 20. PMID: 28937491. View in: PubMed
  • Horowitz JM, Venkatesh SK, Ehman RL, Jhaveri K, Kamath P, Ohliger MA, Samir AE, Silva AC, Taouli B, Torbenson MS, Wells ML, Yeh B, Miller FH. Evaluation of hepatic fibrosis: a review from the society of abdominal radiology disease focus panel. Abdom Radiol (NY). 2017 Aug; 42(8):2037-2053. PMID: 28624924. View in: PubMed
  • Meier JM, Behr SC, Jordan E, Pallav Kolli K, Yeh BM. Intraperitoneal metastases after transarterial embolization of hepatocellular carcinoma: An observational study. Abdom Radiol (NY). 2017 Jun; 42(6):1794-1798. PMID: 28197682. View in: PubMed
  • Hope TA, Aslam R, Weinstein S, Yeh BM, Corvera CU, Monto A, Yee J. Change in Liver Imaging Reporting and Data System Characterization of Focal Liver Lesions Using Gadoxetate Disodium Magnetic Resonance Imaging Compared With Contrast-Enhanced Computed Tomography. J Comput Assist Tomogr. 2017 May/Jun; 41(3):376-381. PMID: 27801693. View in: PubMed
  • Lambert JW, FitzGerald PF, Edic PM, Sun Y, Bonitatibus PJ, Colborn RE, Yeh BM. The Effect of Patient Diameter on the Dual-Energy Ratio of Selected Contrast-Producing Elements. J Comput Assist Tomogr. 2017 May/Jun; 41(3):505-510. PMID: 27824676. View in: PubMed
  • Lambert JW, Sun Y, Gould RG, Ohliger MA, Li Z, Yeh BM. An Image-Domain Contrast Material Extraction Method for Dual-Energy Computed Tomography. Invest Radiol. 2017 Apr; 52(4):245-254. PMID: 27875338. View in: PubMed
  • Patel BN, Alexander L, Allen B, Berland L, Borhani A, Mileto A, Moreno C, Morgan D, Sahani D, Shuman W, Tamm E, Tublin M, Yeh B, Marin D. Dual-energy CT workflow: multi-institutional consensus on standardization of abdominopelvic MDCT protocols. Abdom Radiol (NY). 2017 Mar; 42(3):676-687. PMID: 27888303. View in: PubMed
  • Ikram NS, Yee J, Weinstein S, Yeh BM, Corvera CU, Monto A, Hope TA. Multiple arterial phase MRI of arterial hypervascular hepatic lesions: improved arterial phase capture and lesion enhancement. Abdom Radiol (NY). 2017 Mar; 42(3):870-876. PMID: 27770162. View in: PubMed
  • Dotson B, Lambert JW, Wang ZJ, Sun Y, Ohliger MA, Winklhofer S, Yeh B. Benefit of iodine density images to reduce out-of-field image artifacts at rapid kVp switching dual-energy CT. Abdom Radiol (NY). 2017 Mar; 42(3):735-741. PMID: 27847997. View in: PubMed
  • Cai L, Yeh B, Westphalen AC, Roberts J, Wang ZJ. 3D T2-weighted and Gd-EOB-DTPA-enhanced 3D T1-weighted MR cholangiography for evaluation of biliary anatomy in living liver donors. Abdom Radiol (NY). 2017 Mar; 42(3):842-850. PMID: 27714420. View in: PubMed
  • Yeh MJ, Kim SY, Jhaveri KS, Behr SC, Seo N, Yeh B, et al. Imaging of autoimmune biliary disease. Abdom Radiol (NY). 2017 Jan; 42(1):3-18. PMID: 27639563. View in: PubMed
  • Wells ML, Moynagh MR, Carter RE, Childs RA, Leitch CE, Fletcher JG, Yeh B, Venkatesh SK, et al. Correlation of hepatic fractional extracellular space using gadolinium enhanced MRI with liver stiffness using magnetic resonance elastography. Abdom Radiol (NY). 2017 Jan; 42(1):191-198. PMID: 27511365. View in: PubMed
  • De Cecco CN, Boll DT, Bolus DN, Foley WD, Kaza RK, Morgan DE, Rofsky NM, Sahani DV, Schoepf UJ, Shuman WP, Siegel MJ, Vrtiska TJ, Yeh BM, Berland LL. White Paper of the Society of Computed Body Tomography and Magnetic Resonance on Dual-Energy CT, Part 4: Abdominal and Pelvic Applications. J Comput Assist Tomogr. 2017 Jan; 41(1):8-14. PMID: 27824670. View in: PubMed
  • De Cecco CN, Schoepf UJ, Steinbach L, Boll DT, Foley WD, Kaza RK, Bolus DN, Morgan DE, Sahani DV, Shuman WP, Siegel MJ, Vrtiska TJ, Yeh BM, Berland LL. White Paper of the Society of Computed Body Tomography and Magnetic Resonance on Dual-Energy CT, Part 3: Vascular, Cardiac, Pulmonary, and Musculoskeletal Applications. J Comput Assist Tomogr. 2017 Jan; 41(1):1-7. PMID: 28081050. View in: PubMed
  • Winklhofer S, Lin WC, Lambert JW, Yeh BM. Accessory spleen versus lymph node: Value of iodine quantification with dual-energy computed tomography. Eur J Radiol. 2017 Feb; 87:53-58. PMID: 28065375. View in: PubMed
  • Atreya CE, Greene C, McWhirter RM, Ikram NS, Allen IE, Van Loon K, Venook AP, Yeh BM, Behr SC. Differential Radiographic Appearance of BRAF V600E-Mutant Metastatic Colorectal Cancer in Patients Matched by Primary Tumor Location. J Natl Compr Canc Netw. 2016 Dec; 14(12):1536-1543. PMID: 27956538. View in: PubMed
  • FitzGerald PF, Butts MD, Roberts JC, Colborn RE, Torres AS, Lee BD, Yeh B, Bonitatibus PJ. A Proposed Computed Tomography Contrast Agent Using Carboxybetaine Zwitterionic Tantalum Oxide Nanoparticles: Imaging, Biological, and Physicochemical Performance. Invest Radiol. 2016 Dec; 51(12):786-796. PMID: 27115702. View in: PubMed
  • Siegel MJ, Kaza RK, Bolus DN, Boll DT, Rofsky NM, De Cecco CN, Foley WD, Morgan DE, Schoepf UJ, Sahani DV, Shuman WP, Vrtiska TJ, Yeh B, Berland LL. White Paper of the Society of Computed Body Tomography and Magnetic Resonance on Dual-Energy CT, Part 1: Technology and Terminology. J Comput Assist Tomogr. 2016 Nov/Dec; 40(6):841-845. PMID: 27841774. View in: PubMed
  • Foley WD, Shuman WP, Siegel MJ, Sahani DV, Boll DT, Bolus DN, De Cecco CN, Kaza RK, Morgan DE, Schoepf UJ, Vrtiska TJ, Yeh BM, Berland LL. White Paper of the Society of Computed Body Tomography and Magnetic Resonance on Dual-Energy CT, Part 2: Radiation Dose and Iodine Sensitivity. J Comput Assist Tomogr. 2016 Nov/Dec; 40(6):846-850. PMID: 27768619. View in: PubMed
  • Ehman EC, Umetsu SE, Ohliger MA, Fidelman N, Ferrell LD, Yeh B, Yee J, Hope TA, et al. Imaging prediction of residual hepatocellular carcinoma after locoregional therapy in patients undergoing liver transplantation or partial hepatectomy. Abdom Radiol (NY). 2016 Nov; 41(11):2161-2168. PMID: 27484789. View in: PubMed
  • Winklhofer S, Lambert JW, Sun Y, Wang ZJ, Sun DS, Yeh BM. Pelvic Beam-Hardening Artifacts in Dual-Energy CT Image Reconstructions: Occurrence and Impact on Image Quality. AJR Am J Roentgenol. 2017 Jan; 208(1):114-123. PMID: 27786561. View in: PubMed
  • Srinivasa Babu A, Wells ML, Teytelboym OM, Mackey JE, Miller FH, Yeh B, Ehman RL, Venkatesh SK, et al. Elastography in Chronic Liver Disease: Modalities, Techniques, Limitations, and Future Directions. Radiographics. 2016 Nov-Dec; 36(7):1987-2006. PMID: 27689833. View in: PubMed
  • Yeh B, FitzGerald PF, Edic PM, Lambert JW, Colborn RE, Marino ME, Evans PM, Roberts JC, Wang ZJ, Wong MJ, Bonitatibus PJ, et al. Opportunities for new CT contrast agents to maximize the diagnostic potential of emerging spectral CT technologies. Adv Drug Deliv Rev. 2017 Apr; 113:201-222. PMID: 27620496. View in: PubMed
  • Wang CW, Feng S, Covinsky KE, Hayssen H, Zhou LQ, Yeh B, Lai JC, et al. A Comparison of Muscle Function, Mass, and Quality in Liver Transplant Candidates: Results From the Functional Assessment in Liver Transplantation Study. Transplantation. 2016 Aug; 100(8):1692-8. PMID: 27314169; PMCID: PMC4962324 [Available on 08/01/17]. View in: PubMed, PubMed Central
  • Winklhofer S, Lambert JW, Wang ZJ, Sun Y, Gould RG, Zagoria RJ, Yeh B. Reduction of peristalsis-related gastrointestinal streak artifacts with dual-energy CT: a patient and phantom study. Abdom Radiol (NY). 2016 Aug; 41(8):1456-65. PMID: 26987848; PMCID: PMC4974136 [Available on 08/01/17]. View in: PubMed, PubMed Central
  • Kim SY, Wu EH, Park SH, Wang ZJ, Hope TA, Yee J, Zhao LQ, Chang WC, Yeh B. Comparison of hepatocellular carcinoma conspicuity on hepatobiliary phase images with gadoxetate disodium vs. delayed phase images with extracellular cellular contrast agent. Abdom Radiol (NY). 2016 Aug; 41(8):1522-31. PMID: 26971341. View in: PubMed
  • Chang WC, Sun Y, Wu EH, Kim SY, Wang ZJ, Huang GS, Yeh B, et al. CT Findings for Detecting the Presence of Gangrenous Ischemia in Cholecystitis. AJR Am J Roentgenol. 2016 Aug; 207(2):302-9. PMID: 27249326. View in: PubMed
  • Ehman EC, Behr SC, Umetsu SE, Fidelman N, Yeh BM, Ferrell LD, Hope TA. Rate of observation and inter-observer agreement for LI-RADS major features at CT and MRI in 184 pathology proven hepatocellular carcinomas. Abdom Radiol (NY). 2016 May; 41(5):963-9. PMID: 27193793. View in: PubMed
  • Cai L, Yeh BM, Westphalen AC, Roberts JP, Wang ZJ. Adult living donor liver imaging. Diagn Interv Radiol. 2016 May-Jun; 22(3):207-14. PMID: 26912106; PMCID: PMC4859735. View in: PubMed, PubMed Central
  • Rathnayake S, Mongan J, Torres AS, Colborn R, Gao DW, Yeh B, Fu Y. In vivo comparison of tantalum, tungsten, and bismuth enteric contrast agents to complement intravenous iodine for double-contrast dual-energy CT of the bowel. Contrast Media Mol Imaging. 2016 Jul; 11(4):254-61. PMID: 26892945; PMCID: PMC4969129 [Available on 07/01/17]. View in: PubMed, PubMed Central
  • Wu EH, Kim SY, Wang ZJ, Chang WC, Zhao LQ, Yeh BM. Appearance and Frequency of Gas Interface Artifacts Involving Small Bowel on Rapid-Voltage-Switching Dual-Energy CT Iodine-Density Images. AJR Am J Roentgenol. 2016 Feb; 206(2):301-6. PMID: 26797356; PMCID: PMC4779599 [Available on 02/01/17]. View in: PubMed, PubMed Central
  • Tong GE, Kumar S, Chong KC, Shah N, Wong MJ, Zimmet JM, Wang ZJ, Yee J, Fu Y, Yeh BM. Risk of contrast-induced nephropathy for patients receiving intravenous vs. intra-arterial iodixanol administration. Abdom Radiol (NY). 2016 Jan; 41(1):91-9. PMID: 26830615. View in: PubMed
  • Dhatt HS, Behr SC, Miracle A, Wang ZJ, Yeh BM. Radiological Evaluation of Bowel Ischemia. Radiol Clin North Am. 2015 Nov; 53(6):1241-54. PMID: 26526436; PMCID: PMC4633709 [Available on 11/01/16]. View in: PubMed, PubMed Central
  • Huh J, Kim SY, Yeh BM, Lee SS, Kim KW, Wu EH, Wang ZJ, Zhao LQ, Chang WC. Troubleshooting Arterial-Phase MR Images of Gadoxetate Disodium-Enhanced Liver. Korean J Radiol. 2015 Nov-Dec; 16(6):1207-15. PMID: 26576109; PMCID: PMC4644741. View in: PubMed, PubMed Central
  • Lambert JW, Edic PM, FitzGerald PF, Torres AS, Yeh BM. Complementary contrast media for metal artifact reduction in dual-energy computed tomography. J Med Imaging (Bellingham). 2015 Jul; 2(3):033503. PMID: 26839905; PMCID: PMC4729096 [Available on 09/21/16]. View in: PubMed, PubMed Central
  • FitzGerald PF, Colborn RE, Edic PM, Lambert JW, Torres AS, Bonitatibus PJ, Yeh B. CT Image Contrast of High-Z Elements: Phantom Imaging Studies and Clinical Implications. Radiology. 2016 Mar; 278(3):723-33. PMID: 26356064; PMCID: PMC4770942 [Available on 03/01/17]. View in: PubMed, PubMed Central
  • Leach JR, Elicker B, Yee J, Puppula S, Wisneski JA, Yeh BM. Clot Through the Heart: Paradoxical Embolism With Thrombus-in-Transit at Multidetector Computed Tomography. J Comput Assist Tomogr. 2015 Jul-Aug; 39(4):598-600. PMID: 25756804. View in: PubMed
  • Wu EH, Wojciechowski D, Chandran S, Yeh BM, Park M, Westphalen A, Wang ZJ. Prevalence of abdominal aortic calcifications in older living renal donors and its effect on graft function and histology. Transpl Int. 2015 Oct; 28(10):1172-8. PMID: 26011061. View in: PubMed
  • Kim SY, Park SH, Wu EH, Wang ZJ, Hope TA, Chang WC, Yeh BM. Transient respiratory motion artifact during arterial phase MRI with gadoxetate disodium: risk factor analyses. AJR Am J Roentgenol. 2015 Jun; 204(6):1220-7. PMID: 26001231. View in: PubMed
  • Hope TA, Fowler KJ, Sirlin CB, Costa EA, Yee J, Yeh BM, Heiken JP. Hepatobiliary agents and their role in LI-RADS. Abdom Imaging. 2015 Mar; 40(3):613-25. PMID: 25287679. View in: PubMed
  • Lambert JW, Kumar S, Chen JS, Wang ZJ, Gould RG, Yeh BM. Investigating the CT localizer radiograph: acquisition parameters, patient centring and their combined influence on radiation dose. Br J Radiol. 2015 Apr; 88(1048):20140730. PMID: 25608494; PMCID: PMC4651250. View in: PubMed, PubMed Central
  • Tillack AA, Joe BN, Yeh BM, Jun SL, Kornak J, Zhao S, Deng D. Vaginal shape at resting pelvic MRI: predictor of pelvic floor weakness? Clin Imaging. 2015 Mar-Apr; 39(2):285-8. PMID: 25457574. View in: PubMed
  • Valenzuela DM, Behr SC, Coakley FV, Wang ZJ, Webb EM, Yeh BM. Computed tomography of iatrogenic complications of upper gastrointestinal endoscopy, stenting, and intubation. Radiol Clin North Am. 2014 Sep; 52(5):1055-70. PMID: 25173658. View in: PubMed
  • Jha RC, Mitchell DG, Weinreb JC, Santillan CS, Yeh BM, Francois R, Sirlin CB. LI-RADS categorization of benign and likely benign findings in patients at risk of hepatocellular carcinoma: a pictorial atlas. AJR Am J Roentgenol. 2014 Jul; 203(1):W48-69. PMID: 24951229. View in: PubMed
  • Somsouk M, To'o K, Ali M, Vittinghoff E, Yeh BM, Yee J, Monto A, Inadomi JM, Aslam R. Esophageal varices on computed tomography and subsequent variceal hemorrhage. Abdom Imaging. 2014 Apr; 39(2):251-6. PMID: 24366107; PMCID: PMC3979277. View in: PubMed, PubMed Central
  • Schneider JG, Wang ZJ, Wang W, Yee J, Fu Y, Yeh BM. Patient-tailored scan delay for multiphase liver CT: improved scan quality and lesion conspicuity with a novel timing bolus method. AJR Am J Roentgenol. 2014 Feb; 202(2):318-23. PMID: 24450671. View in: PubMed
  • Miracle AC, Behr SC, Benhamida J, Gill RM, Yeh B. Mesenteric inflammatory veno-occlusive disease: radiographic and histopathologic evaluation of 2 cases. Abdom Imaging. 2014 Feb; 39(1):18-24. PMID: 24318211. View in: PubMed
  • Zissen MH, Wang ZJ, Yee J, Aslam R, Monto A, Yeh BM. Contrast-enhanced CT quantification of the hepatic fractional extracellular space: correlation with diffuse liver disease severity. AJR Am J Roentgenol. 2013 Dec; 201(6):1204-10. PMID: 24261358. View in: PubMed
  • Chu LL, Webb EM, Stengel JW, Yeh BM, Lu Y, Coakley FV. CT of acute appendicitis: can diagnostic accuracy serve as a practical performance metric for readers specialized in abdominal imaging? Clin Imaging. 2014 Jan-Feb; 38(1):56-9. PMID: 24080371. View in: PubMed
  • Kelley RK, Hwang J, Magbanua MJ, Watt L, Beumer JH, Christner SM, Baruchel S, Wu B, Fong L, Yeh BM, Moore AP, Ko AH, Korn WM, Rajpal S, Park JW, Tempero MA, Venook AP, Bergsland EK. A phase 1 trial of imatinib, bevacizumab, and metronomic cyclophosphamide in advanced colorectal cancer. Br J Cancer. 2013 Oct 01; 109(7):1725-34. PMID: 24022191; PMCID: PMC3790192. View in: PubMed, PubMed Central
  • Wang W, Wang ZJ, Webb EM, Westphalen AC, Gross AJ, Yeh BM. Omental infarction preceded by anatomically upturned omentum. Clin Imaging. 2013 Nov-Dec; 37(6):1125-7. PMID: 23932388. View in: PubMed
  • Zhang LJ, Luo S, Yeh BM, Zhou CS, Tang CX, Zhao Y, Li L, Zheng L, Huang W, Lu GM. Diagnostic accuracy of three-dimensional contrast-enhanced MR angiography at 3-T for acute pulmonary embolism detection: comparison with multidetector CT angiography. Int J Cardiol. 2013 Oct 12; 168(5):4775-83. PMID: 23958419. View in: PubMed
  • Penn A, Wang W, Wang ZJ, Yee J, Webb EM, Yeh BM. Demographics and frequency of the intermittently upturned omentum at CT. Eur J Radiol. 2013 Nov; 82(11):e637-40. PMID: 23906439. View in: PubMed
  • Mongan J, Rathnayake S, Fu Y, Gao DW, Yeh BM. Extravasated contrast material in penetrating abdominopelvic trauma: dual-contrast dual-energy CT for improved diagnosis--preliminary results in an animal model. Radiology. 2013 Sep; 268(3):738-42. PMID: 23687174; PMCID: PMC3750414. View in: PubMed, PubMed Central
  • Keedy AW, Breiman RS, Webb EM, Roberts JP, Coakley FV, Yeh BM. Determinants of second-order bile duct visualization at CT cholangiography in potential living liver donors. AJR Am J Roentgenol. 2013 May; 200(5):1028-33. PMID: 23617485. View in: PubMed
  • Kelley RK, Nimeiri HS, Munster PN, Vergo MT, Huang Y, Li CM, Hwang J, Mulcahy MF, Yeh BM, Kuhn P, Luttgen MS, Grabowsky JA, Stucky-Marshall L, Korn WM, Ko AH, Bergsland EK, Benson AB, Venook AP. Temsirolimus combined with sorafenib in hepatocellular carcinoma: a phase I dose-finding trial with pharmacokinetic and biomarker correlates. Ann Oncol. 2013 Jul; 24(7):1900-7. PMID: 23519998; PMCID: PMC3690907. View in: PubMed, PubMed Central
  • Webb EM, Wang ZJ, Westphalen AC, Nakakura EK, Coakley FV, Yeh BM. Can CT features differentiate between inferior vena cava leiomyosarcomas and primary retroperitoneal masses? AJR Am J Roentgenol. 2013 Jan; 200(1):205-9. PMID: 23255763. View in: PubMed
  • Varenika V, Fu Y, Maher JJ, Gao D, Kakar S, Cabarrus MC, Yeh BM. Hepatic fibrosis: evaluation with semiquantitative contrast-enhanced CT. Radiology. 2013 Jan; 266(1):151-8. PMID: 23169796; PMCID: PMC3528968. View in: PubMed, PubMed Central
  • Sai V, Rakow-Penner R, Yeh BM, Coakley FV, Westphalen AC, Webb EM, Wang ZJ. Renal cyst pseudoenhancement at 16- and 64-dector row MDCT. Clin Imaging. 2013 May-Jun; 37(3):520-5. PMID: 23102928. View in: PubMed
  • Mongan J, Rathnayake S, Fu Y, Wang R, Jones EF, Gao DW, Yeh BM. In vivo differentiation of complementary contrast media at dual-energy CT. Radiology. 2012 Oct; 265(1):267-72. PMID: 22778447; PMCID: PMC3447173. View in: PubMed, PubMed Central
  • Kane AJ, Wang ZJ, Qayyum A, Yeh BM, Webb EM, Coakley FV. Frequency and etiology of unexplained bilateral hydronephrosis in patients with breast cancer: results of a longitudinal CT study. Clin Imaging. 2012 Jul-Aug; 36(4):263-6. PMID: 22726962. View in: PubMed
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Professor
Director, Contrast Material and CT Translational Research Lab
Professor in Residence