Imaging Research Symposium

The Radiology and Biomedical Imaging Research Symposium is open to all in the UCSF and scientific communities and features speaker presentations and a scientific poster session highlighting the innovative work being done in the department. A broad spectrum of topics are covered including cancer, neurodegenerative disease, musculoskeletal disease and cardiovascular disease. Information is provided on research in the areas of CT, MR, PET, SPECT, MEG, EEG, optical imaging, and ultrasound. In addition, medical informatics, and MR/CT contrast agent development are addressed.

The Hasegawa Award, honoring the memory of Bruce Hasegawa, PhD, recognizes the research of an outstanding Radiology and Biomedical Imaging graduate student or postdoctoral scholar, and is presented each year at the conclusion of the symposium.

2020 Imaging Research Symposium (Virtual)
The 17th Annual Imaging Research Symposium
Department of Radiology and Biomedical Imaging
University of California, San Francisco

October 14, 2020

2020 Imaging Research Symposium

Welcome Remarks
  • Sharmila Majumdar, PhD, Vice Chair, Research, UCSF Radiology and Biomedical Imaging
  • Christopher P. Hess, MD, PhD, Alexander R. Margulis Professor and Chair, UCSF Radiology and Biomedical Imaging

Podium Presentations, Session I
Each presenter will speak for eight minutes, with two minutes for questions

Time Speaker Title Topic
1:10-1:20pm Leynes, Andrew P. Training- and Database-free Deep Non-Linear Inversion (DNLINV) for Highly Accelerated Autocalibrated Parallel Imaging MRI MRI Tech/Deep Learning
1:20-1:30pm Guglielmetti, Caroline Improving brain lesion characterization in a multiple sclerosis model using [18F]F-AraG PET and MR imaging of T-cells and inflammatory demyelination Nuclear Med
1:30-1:40pm Rowley, Paul A 7 Tesla Diffusion Tensor Imaging and Quantitative Susceptibility Mapping of Huntington’s Disease Neuro Functional
1:40-1:50pm Caliva, Francesco Ultrafast multitask: MRI reconstruction and tissue segmentation MRI Tech/Deep Learning
1:50-2:00pm Joseph, Gabby Effect of Weight Cycling on Progression of Knee Joint Degenerative Disease in Overweight and Obese Individuals: 4-Year MRI Data from the Osteoarthritis Initiative MRI Clinical
2:00-2:10pm Li, Wen The effect of background parenchymal enhancement on the predictive performance of functional tumor volume measured in MRI Cancer/Breast/MRI
2:10-2:20pm Olson, Marram  Clinical Validation Study of Machine Learning Algorithms for Liver Transplant Planning Clinical/Deep Learning
2:20-2:30pm Polvoy, Ilona First-in-human biodistribution and radiation dosimetry of [11C]-D-methionine, a novel PET radiotracer targeting bacterial infection Nuclear Med

2:40-3:35 pm Poster Session

6 simultaneous sessions via zoom breakout rooms.

Room 1 - Topic: Cancer

Moderator: Dr. Michael Evans

Poster Name Title
7 Sinan Wang Molecular imaging of prostate cancer targeting CD46 using immunoPET
15 Natsuko Onishi

Lack of Background Parenchymal Enhancement Suppression in Breast MRI During Neoadjuvant Chemotherapy may be Associated with Inferior Treatment Response In Hormone Receptor Positive Breast Cancer

27 Deep K. Hathi           

Evaluation of primary breast cancers using dedicated breast PET and whole-body PET

34 Alex Nguyen Comparison of Segmentation Methods in Assessing Background Parenchymal Enhancement as a Biomarker for Response to Neoadjuvant Therapy
35 Courtney Lawhn Heath

Gallium-68 Prostate Specific Membrane Antigen (68Ga-PSMA) PET for Imaging of Thyroid Cancer: A Feasibility Study

50 Jack C. Williams

Repeatability of Diffusion-Weighted Imaging and DCE-MRI of the Prostate in an Active Surveillance Population

54 Matthew Gibbons

Multiparametric MR Imaging Characteristics of Benign Prostate Tissues Referenced to Whole Mount Histopathology

57 Jessica Gibbs Operational Standardization and Quality Assurance Yield High Acceptance Rate for Breast MRI in the I-SPY 2 TRIAL
63 Niranjan Meher Development of Prostate-Specific Membrane Antigen Targeted Theranostic Nanoparticles to Treat Prostate Cancer Using Boron Neutron Capture Therapy
82 Emilie Decavel-Bueff

Prostate Cancer Patient-Derived Xenograft Model Development and MR Imaging Characterization

85 Joao Piraquive

The Pathologic and Metabolic Characterization of Patient-Derived Renal Cell Carcinoma Murine Models

Room 2 - Topic: Deep Learning

Moderator: Dr. Khai Vu

Poster Name Title
18 Nikan Namiri Symptomatic and Structural Progression of Knee Osteoarthritis are Associated with Morphological Phenotypes: A Magnetic Resonance Imaging and Deep Learning Study
20 Abhejit Rajagopal

Enhancing PET/MRI with Deep Domain-Translated Zero-Dose PET

28 Alejandro G. Morales Martinez       

Multimodal qMRI Framework for Knee Imaging Biomarker Fusion and Osteoarthritis Prediction

31 Julia Cluceru Automatic Stratification of Gliomas Into WHO 2016 Molecular Subtypes Using Diffusion-Weighted Imaging and a Pre-Trained Deep Neural Network
49 Jenny Lee

Deep Learning Survival Analysis: Application to Knee Pain Development

52 Tyler Gleason

Volumetric Response Assessment in Low-Grade Glioma: Towards a Fully Automated and Clinically Deployable Workflow

59 Madeline Hess

Learning for Automatic Segmentation and 3D Representation of the Lumbar Spine

60 Caroline Tran Automated Fetal Brain Volumetry on Clinical Fetal MRI Using Convolutional Neural
62 Kenneth T. Gao Automatic Detection and Mapping of Vertebral Body Modic Changes
72 Felix Liu

Improving Radiographic Osteoarthritis Prediction in Deep Learning with Hard and Soft Parameter Sharing Multi-Task Neural Networks

84 Jacob Ellison

Improving the Generalizability of Convolutional Neural Networks for Brain Tumor Segmentation in the Post-Treatment Setting

45 Pablo F. Damasceno Deep Learning Glioma Segmentation: From Training to Clinical Deployment

Room 3 - Topic: Hyperpolarized C13 Imaging

Moderators: Drs. Yan Li and Michael Ohliger

Poster Name Title
11 Donghyun Hong

Quantification Pipeline for in-vivo Hyperpolarized 13C Magnetic Resonance Spectroscopy

13 Changhua Mu

Optimization of Hyperpolarized Carbon-13 pH Imaging Methods in Preparation for Clinical Translation in Prostate Cancer

17 Georgios Batsios

Hyperpolarized δ-[1-13C]gluconolactone monitors TERT-induced elevation in Pentose Phosphate Pathway Flux in Brain Tumors in vivo

19 Jasmine Graham Simulation and Application of a Multi-Resolution Hyperpolarized 13C MRI Approach for Improved Quantification of Brain Metabolism
22 Nicholas Dwork

Improved Hyperpolarized Imaging By Exploiting Temporal Correlations

30 Kai Qiao

Non-invasive Differentiation of M1 and M2 Activation in Macrophages using Hyperpolarized 13C MRS of Pyruvate and DHA at 1.47 Tesla

33 Caroline Guglielmetti

Hyperpolarized 13C MRSI of Pyruvate and Urea Detects Immunomodulatory Therapy Response in a Multiple Sclerosis Model

40 Yaewon Kim

Denoising of Hyperpolarized 13C MR Images Using Patch-based Tensor Singular Value Decomposition

58 Hecong Qin

Clinical Translation of Simultaneous Hyperpolarized 13C Metabolic and Perfusion Imaging

64 Manushka Vaidya

A 13C/31P surface Coil to Visualize Metabolism and Energetics in the Brain

66 Adam Autry Initial experience: detection of aberrant hyperpolarized [1-13C]pyruvate metabolism in patients with GBM prior to resection
23 Philip M. Lee

Characterization of Arterial and Portal Venous Contributions to Metabolic Imaging of the Human Liver Using Hyperpolarized 13C-pyruvate MRI

Room 4 - Topic: Methodological and Device Development or Testing

Moderator: Dr. Peder Larson

Poster Name Title
8 Kisoo Kim

Motion-robust, Multi-Slice, Real-Time MR PRFS Thermometry for MR-Guided Ultrasound Thermal Therapy In Abdominal Organs

26 Bridget Kilbride

Design and Evaluation of an XMR-visible Catheter for Stroke Applications

42 Jessica E. Scholey

High-Accuracy Calculation of Stopping Power Ratios using MRI And MVCT For Proton Radiotherapy

47 Misung Han

Efficient Measurement of Composite Metric R2–R1ρ in Knee Cartilage

51 Teffany Joy Bareng

Assessment of Clip Locations on Breast MRI During NAC to Guide Tumor Bed Biopsy at Mid-Treatment

53 Huawei Liu

Atlas-based Adaptive Hadamard-encoded 2D MRSI at 3T

69 Keerthi S. Valluru

A Bench-Top Phantom That Can Mimic Idiopathic Intracranial Hypertension And Transverse Sinus Stenosis

86 Lisa Wilmes

Multi-Site Evaluation of MRI Breast Phantom with Integrated MR-Visible Liquid Crystal Thermometer: Initial Temperature and DWI Measurements

87 Fei Tan

Registration Methods Comparison and Reproducibility Study on Pulmonary Ventilation Analysis Using Ultra-Short Echo Time (UTE) Lung MRI

5 Nikki Okwelogu

Comparison of Fine Needle Aspiration and Core Needle Biopsy Technique in the Diagnosis of Lipomatous Lesions

Room 5 - Topic: Neuroimaging

Moderators: Drs. Linda Chao and Esther Yuh

Poster Name Title
12 Xuan T. Ly

Brain Reactivity to Vaping Cues in adolescent E-cigarette Smokers

37 Alison Myoraku Age-Trajectory of Brain Morphometry Across the Lifespan in Major Depressive Disorder: Unique to Depression or Universal in Aging?
43 Nikhil Deveshwar

Quantification of T1 and Relative Proton Density in the Brain Ultrashort-T2* Component

55 Xiao Gao Quantification of Mutation-dependent Heterogeneity In Murine Models of Cerebral Small Vessel Disease using Multimodal MR Imaging At 14.1 Tesla
74 Leighton Hinkley Anomalous Language Lateralization in Adults with Reading Disability as a Consequence of Reduced Left-sided Occipito-temporal Activation
76 Karuna Subramaniam Multivariate Pattern Analysis of Brain Structure Predicts Functional Outcome after Auditory-based Cognitive Training Interventions
77 Kamalini G. Ranasinghe Reduced Synchrony of Alpha Oscillations during Life Predicts Postmortem Neurofibrillary Tangle Burden in Alzheimer’s Disease
83 Melanie Morrison Functional Connectivity is Associated with Radiotherapy-Induced Cognitive Impairment in Young Brain Tumor Survivors
46 Kendall C. Parks Cerebral Perfusion Correlates of Childhood Abuse and Neglect in Adolescents
67 Namasvi B. Jariwala Brain Activation Correlates of Perceived Everyday Life Stress in Adolescents

Room 6 - Topic: Novel Methods for Clinical and Preclinical Studies

Moderators: Drs. Robert Flavell and Henry VanBrocklin

Poster Name Title
16 Evan Calabrese Volumetric and Regional Atlas-Based Analysis of Diffusion MRI for Neuroprognistication in Comatose Cardiac Arrest Patients
21 Upasana U. Bharadwaj Disc-Dural Sac Ratio (DDSR): A Practical Metric Correlating with Lumbar Spinal Canal Stenosis
41 Darren Hsu Intensity Based Visualization of Pulmonary Function Using Time to Peak (TTP) and Full Width at Half Max (FWHM) Biomarkers on Ultrashort Echo Time (UTE) MRI
48 Shezhang Lin Color-coded 3D Printing Modeling of Cardiovascular Blood Pool and Structure from CTA/MRA Image for Clearly Defining and Presenting the Complicated Circulatory and Anatomic Abnormalities in Adult Congenital Heart Disease
65 Joshua Chen How Good is Ultrasound FNA For Neck Lymph Nodes? Single-Institution Review of Diagnostic Adequacy and Associated Features
71 Vahid Ravanfar Impact of Reformatting Brain PET Images to the AC-PC line of MR images
73 Matthew F. Parker PET Imaging of Bacterial Infection: A Trio of Pathogens and a Trio of Infection Models
78 Rutwik Shah Swarm Intelligence: A Novel Clinical Strategy for Improving Imaging Annotation Accuracy, using Wisdom of the Crowds
80 Denis Beckford-Vera Imaging Viral Load and T Cell Activation In HIV: Tools for Cure Development
6 Jonathan Tranel Effect of Microdistribution of Targeted Radionuclide Therapies on Delivered Absorbed Dose In a GATE Model of Bone Marrow

Podium Presentations, Session II
Each presenter will speak for eight minutes, with two minutes for questions

Time Speaker Title Topic
3:45-3:55pm Valluru, Keerthi Prototype of a microphone enabled catheter to quantify venous pulsatile tinnitus Devices/Hardware
3:55-4:05pm Lafontaine, Marisa Metabolic Characterization of Pre-Surgical Lower Grade Glioma Using Spectroscopic Imaging Optimized for 2-HG Detection Neuro Brain Tumor
4:05-4:15pm Mueller, Angela M. Staying Abstinent Isn’t Easy: Substantial Re-Configuration of the Intrinsic Whole-Brain-Network Architecture in Alcohol Abstainers Neuro Functional
4:15-4:25pm Agarwal, Shubhangi 
Hyperpolarized 13C MR imaging of metastatic prostate cancer murine models
Hyperpolarized 13C
4:25-4:35pm Chiu, Le Wen Factors predicting metastic disease in 68Ga-PSMA-11 PET positive osseous lesions in prostate cancer Nuclear Med
4:35-4:45pm Sipes, Benjamin S.
Structural Default Mode Network (DMN) Connectivity and Adolescent Prosocial Behavior Neuro Functional
4:45-4:55pm Tolpadi, Aniket Reduction of 3D Spine Quantitative MRI Acquisition Time using Recurrent Encoder-Decoder Deep Learning Network MRI Tech/Deep Learning
4:55-5:05pm Morrison, Melanie
Resting-state functional MRI signal variability correlates with medication responsiveness in patients with Parkinson’s disease
Neuro Functional

5:05pm Awards

  • Bruce Hasegawa Award - presented by Youngho Seo, PhD
  • Rahul Desikan Award - presented by Christopher P. Hess, MD, PhD
  • Best Posters Presentation (6 winners) - presented by Valentina Pedoia
  • Best Podium Presentation (1 winner) - presented by Valentina Pedoia
  • Raffle - Evaluation 

Past Imaging Research Symposiums

2019 Imaging Research Symposium

1-1:15 pm Welcome Remarks
Sharmila Majumdar, PhD and Christopher Hess, MD, PhD
1:15-2:35pm Session I
Robert Flavell, MD, PhD and Valentina Pedoia, PhD

Impact of Hybrid Supervision Approaches on the Performance of Artificial Intelligence for the Classification of Chest Radiographs
Ryan J. Ellis


Efficacy of 2D and 3D Convolutional Neural Networks in Severity Staging of Anterior Cruciate Ligament Injuries
Nikan Namiri

1:35-1:45pm Deep learning-based synthetic post-contrast T1-weighted MR imaging of glioblastomas
Evan Calabrese, MD, PhD
1:45-1:55pm Learning Osteoarthritis Imaging Biomarkers from Bone Surface Spherical Encoding
Alejandro Morales Martinez
1:55-2:05pm Structural and Functional Abnormalities of the Dorsal Anterior Cingulate Cortex in Obsessive-Compulsive Disorder
Milan Manchandia, MD

Hyperpolarized In vivo pH Imaging Reveals Grade-Dependent Acidification in Prostate Cancer
David Korenchan, PhD


MR Guided Focused Ultrasound for Treatment of Lower Back Pain
Roland Krug, PhD


Translation of 89Zr-VRC01 for PET/MR Imaging of Persistent HIV: First-in-human
Denis Beckford-Vera, PhD

2:35-3:05pm Coffee Break

Session II
Moderators: Peder Larson, PhD and Michael Ohliger, MD, PhD  

3:05-3:15pm Early Non-Invasive Prediction of Response to Temozolomide in Low-Grade Glioma
Marina Radoul, PhD

Evaluation of Vertebral Discitis Osteomyelitis using 11C-D-alanine PET Imaging
Matthew F. Parker, PhD


Neuroimaging Correlates of White Matter Hyperintensity Burden and MTHFR Gene in Relation to Beta-Amyloid in Healthy Elderly
Priya Rajagopalan

3:35-3:45pm Global and Focal Effects of Radiation Therapy on the Cerebral Vasculature in Pediatric Brain Tumor
Sivakami Avadiappan
3:45-3:55pm Associations between Multi-joint Data Driven Biomechanical Features Extracted During Walking and Hip Cartilage Degeneration Changes from Quantitative MRI
Koren Roach, PhD

Di-Chromatic Super Resolution Interpolation of Magnetic Resonance Imagery
Jeremy Gordon, PhD


Combined Metabolic And Perfusion Imaging by Hyperpolarized 13C MR can Evaluate Early and Dose-Dependent Tumor Response to Radiotherapy
Hecong Qin

4:15-4:25pm Dedicated Breast PET for Detection of Early Treatment Response in Breast Cancer Patients
Ella Jones, PhD

Poster Presentations

# Presenting Author Abstract Title
1 Kirti Magudia Prediction of Clinically Significant Prostate Cancer in Patients Undergoing Fusion Biopsy Using Machine Learning: Lessons Learned from Dataset Assembly at UCSF
2 Eugene Ozhinsky Deep Learning Pipeline for Automated Identification of Osteoarthritic Degenerative Changes in the Hip
3 Jenny Lee Predicting Pain Trajectories in Knee Osteoarthritis Subjects by Learning Image Biomarkers from Structural MRI
4 Qing Dai Deep Learning-Based Prediction of Renal Cancer Grading from Contrast- Enhanced CT
5 Aniket Tolpadi Deep Learning-Based Total Knee Replacement Prediction from Magnetic Resonance Images and Biomarker Analysis
6 Francesco Caliva A Shape Aware Loss for Semantic Segmentation
7 Jae Ho Sohn Prediction of Future Healthcare Expenses of Patients from Chest Radiographs Using Deep Learning
8 Radhika Tibrewala Deep Learning Based Hip Abductor Muscle Segmentation and Association of Muscle Fat Fraction with Early OA Cartilage Degeneration Biomarkers
9 Yicheng Chen QSMGAN: Improved Quantitative Susceptibility Mapping using 3D Generative Adversarial Networks with Increased Receptive Field
10 Razmjoo Alaleh Semi-supervised Graph-based Deep Learning for Multi-Modal Prediction of Osteoarthritis
11 James Hawkins cI2 Platform for Rapid Development and Clinical Translation of ML Models
12 Yan Wang A Multi-Object Machine Learning Algorithm using Fully Conventional Network for Cardiac LV and RV Segmentation
13 Pablo F. Damasceno Evaluating Neurodegeneration Severity by Spectral Embedding Manifolds
14 Rima Aranout Precision Phenotyping for Biomedical Imaging Using Deep Learning
15 Juliea Cluceru Machine Learning Methods to Classify MRI Images for Automated Longitudinal Analysis
16 Hardik Kothare Cortical dynamics of the speech motor control network in the non-fluent variant of Primary Progressive Aphasia
17 Elavarasan Subramani Hyperpolarized [2-13C] pyruvate to [5-13C] glutamate as biomarker of IDH1 mutant glioma response to temozolomide therapy
18 Jasmine Graham Simulation and Application of a Variable Resolution Echo-Planar Imaging Approach for Improved Quantification of Hyperpolarized 13C Metabolism
19 Georgios Batsios Detection of _-glutamyl-transferase activity up-regulation in orthotopic glioma using hyperpolarized _-glutamyl-[1-13C]glycine
20 Christina Mueller Multiparametric structural brain connectivity and suicidal ideation in adolescents
21 Susanne Mueller Mapping the internal brainstem structures using MP2RAGE derived T1 weighted and T1 relaxation images at 3 and 7T
22 Philip M. Lee Development of Computational Methods for B1-Corrected Hyperpolarized 13C MRI Human Studies
23 Joseph Blacha Automated synthesis of 5-[18F]fluoro-alpha-methyl tryptophan (5-[18F]F-AMT) to image breast cancer brain metastases in rodent
24 Abby Molloy Mutant isocitrate dehydrogenase 1/2 inhibition induces a unique MRS-detectable metabolic signature in low-grade gliomas
25 Thomas R. Hayes Automated radiosynthesis of O-(2-[18F]fluoroethyl)-O-(4-nitrophenyl)methylphosphonate: a PET tracer surrogate of VX
26 Vahid Ravanfar Positioning focus shim in phase direction impacts image quality in DWI sequences
27 Yan Li Placental thickness correlates with placenta accreta spectrum (PAS) disorder in women with placenta previa.
28 Xucheng Zhu 5-minute non-sedated neonatal and pediatric pulmonary UTE based MRI studies
29 Junnian Wei Proteomic profiling of the cell surfaceome identifies new theranostic targets for cancer cells driven by hyperactive mTORC1 signaling
30 Pavithra Viswanath Imaging a hallmark of cancer: hyperpolarized 13C-magnetic resonance spectroscopy can non-invasively monitor TERT expression in low-grade gliomas in vivo
31 Douglas G. Peters Multimodal MRI Analysis of Cerebral Blood Flow and Free Water Fraction in ADNI3 Cohort
32 Jeremy Gordon Probing Cerebral Lactate Compartmentalization with Hyperpolarized Diffusion Weighted 13C MRI
33 Sinan Wang Amino Acid-Derived Sensors For Specific Zn2+ Detection Using Hyperpolarized 13C Magnetic Resonance Spectroscopy
34 Lydia Le Page Imaging cerebral ketone metabolism with hyperpolarized 13C beta-hydroxybutyrate
35 Jessica E. Scholey Methodology for high-accuracy calculation of SPR using multimodal imaging
36 Duygu Tosun Cortical Thickness and Cerebral Blood Perfusion Abnormalities Correlated with Depression in a Geriatric Population
37 Kendall C. Parks A preliminary study of the association between cerebral perfusion and childhood trauma in adolescents
39 Magdalena Posadzy Lipodystrophy in HIV-infected patients assessed with QCT
40 Zhuo Chen Proteomic profiling of the cellular surfaceome reveals new targets for potential theranostic applications in cancers driven by TERT promoter mutations
41 Alex Nguyen Bias Correction for Improved Segmentation and Background Parenchymal Enhancement Calculation in Multi-Center Breast MRI Trials
42 Dharshan Chandramohan Anthropomorphic skull phantom using quantitatively accurate bone mimic material
43 Yuting Wang Application of high-resolution intracranial vessel wall MRI for pediatric vasculopathy: institutional experience in 5 years
44 Hsin-Yu Chen Tensor Signal Enhancement and Optimal Multichannel Receiver Combination Analyses For Human Hyperpolarized 13C MRI
45 Brian T. Chung Investigating Human Brain Metabolism using Hyperpolarized [2-13C]Pyruvate
46 Adam Autry Serial characterization of HP [1-13C]pyruvate metabolism in the brains of patients with glioma and healthy controls
47 Mithun Diwakar

Robust and Efficient High-resolution Beamformer Reconstruction of Magnetoencephalographic Brain Imaging Data Using Low-Resolution Sparse Bayesian Learning

48 Misung Han Simultaneous Multi-Slice Spin and Gradient Echo Dynamic Susceptibility-Contrast Perfusion Imaging of Gliomas
49 Keerthi S. Valluru Idiopathic intracranial hypertension and transverse sinus stenosis phantom to evaluate pathophysiology: Preliminary results
50 Kai Qiao Non-invasive Detection of M1 Activation in Macrophages using Hyperpolarized [1-13C] Dehydroascorbic Acid
51 Ting Sun Selective hyperpolarized 13C metabolic signal suppression from a liver-specific gadolinium contrast agent measured using an NMR-compatible perfusion bioreactor
52 Fei Tan Pulmonary Ventilation Analysis Using Motion-Resolved Ultrashort Echo (UTE) MRI
53 Natsuko Onishi Quantitative whole-tumor kinetic assessment: comparison between invasive ductal and lobular carcinoma
54 Namasvi Jariwala Network integration reflects attention performance in adolescents
55 Nikhil Deveshwar Characterization of ultrashort T2* components in brain myelin
56 Jinny Sun Identifying the Metabolic Signature of Castration-Resistant Prostate Cancer and its Early Metabolic Response to Androgen Pathway Inhibitor ARN-509
57 Kesav Raghavan Reporting Coronary Artery Calcification on Non-Contrast Chest CTs: A Quality Improvement Initiative
58 An Vu Evaluating the impact of respiratory related B0 fluctuations on both SILK and EPI based mesoscale resolution fMRI at 7T
59 Huawei Liu Accelerated Simultaneous Multi-slice MRS by Hadamard-encoded Excitation and Sensitivity Encoding (SENSE)
60 Shubhangi Agarwal Hyperpolarized C13 MR imaging of modulations in prostate cancer metabolism as a response to therapy
61 Kenneth T. Gao Voxel-based Relaxometry of Knee Articular Cartilage T1rho and T2 Relaxation in Collegiate Basketball Players: A Multicenter Study
62 Angela M. Mueller The intrinsic network organization differs in individuals with alcohol use disorders (AUD) as a function of relapse status
63 Lisa Wilmes Effect of DWI sequence on geometric measurement errors in a breast phantom
64 Wen Li The effect of patient motion on functional tumor volume measured by DCE breast MRI in the prediction of pCR for neoadjuvant therapy
65 Yangjie Huang [18F]-YJH08, a PET radioligand for multidimensional analysis of glucocorticoid receptor expression in vivo.
66 Ning Zhao Measuring Dynamic Changes in the Labile Iron Pool in Vivo with a Reactivity-Based Probe for Positron Emission Tomography
67 Joao Piraquive Hyperpolarization [1-13C] pyruvate magnetic resonance spectroscopy imaging to detect metabolic changes in liver in a high-fat diet rat model
68 Kevin McGill Incidence of Incidental Intrapelvic Findings on Pelvis MR

2018 Imaging Research Symposium

2018 Imaging Research Symposium

October 23, 2018

Symposium Program

12:30 pm  Registration & Poster Highlights
Health Sciences West - Room HSW301
1:00-1:10 pm  Opening Remarks
Christopher P. Hess, MD PhD, Professor and Chair of the Department of Radiology and Biomedical Imaging
Sharmila Majumdar, PhD, Professor and Vice Chair for Research, Department of Radiology and Biomedical Imaging
1:10-2:30 pm  Oral Presentations (Session I)
Moderators: Rita Freimanis, MD and Jing Liu, PhD
1:10-1:20 pm  A shallow introduction to deep learning methods for neuroimaging researchers and radiologists 
John Colby MD PhD, Pratik Mukherjee MD PhD
1:20-1:30 pm  Artificial Intelligence System for Fully-Automated Characterization & Diagnosis of Brain MRI Lesions 
Andreas Rauschecker MD PhD, Long Xie PhD, Jiancong Wang, Emmanuel Botzolakis MD PhD, Ilya Nasrallah MD PhD, Nick Bryan MD PhD, Tessa Cook MD PhD, Suyash Mohan MD, James Gee PhD, and Jeffrey Rudie MD PhD.
1:30-1:40 pm  Large Scale Deidentification of DICOM Medical Imaging Data for Computational Health Science Research at UCSF 
Marram (Beck) Olson, James Hawkins, Ritika Maheshwari, Joe Hesse, Wyatt Tellis, Emma Bahroos, Paul Rowley, Dana Ludwig, Eugenia Rutenberg, Gundof Schenk, Sharmila Majumdar, Jason C. Crane
1:40-1:50 pm  Neural correlates of smartphone dependence in adolescents 
Olga Tymofiyeva, Justin P. Yuan, Roma Kidambi, Chiung-Yu Huang, Henje Blom E, Tony T. Yang, Duan Xu
1:50-2:00 pm  Imaging brain inflammation using hyperpolarized 13C MRSI of pyruvate and urea in a model of multiple sclerosis 
Caroline Guglielmetti, Christian Cordano, Ari Green, Myriam M. Chaumeil
2:00-2:10 pm  Evaluating patients with Glioma using Multi-modal hyperpolarized C-13 and H-1 Metabolic Imaging 
Yan Li, Adam Autry, Jeremy Gordon, Hsin-Yu Chen, Jason Crane, Beck Olson, Marisa Lafontaine, Ilwoo Park, Javier Villanueva-Meyer, Daniel Vigneron, Susan Chang and Sarah Nelson
2:10-2:20 pm  Distinguishing metabolic signals of liver tumors from surrounding liver cells using hyperpolarized 13C MRI and Gadoxetate 
Shubhangi Agarwal, Jeremy Gordon, Natalie Korn, Robert A. Bok, Cornelius Von Morze, Daniel B. Vigneron, John Kurhanewicz, Michael A. Ohliger
2:20-2:30 pm  Androgen Independence Leads to Altered Metabolism in Prostate Cancer Cell and Murine Models 
Jinny Sun, Justin Delos Santos, Robert Bok, Romelyn Delos Santos, Mark Van Criekinge, Daniel B. Vigneron, Renuka Sriram, John Kurhanewicz
2:30-3:00 pm  Coffee Break
3:00-4:20 pm  Oral Presentations (Session II)
Moderators: Michael Ohliger, MD, PhD and Valentina Pedoia, PhD
3:00-3:10 pm  Reducing Bowel Peristalsis Artifact with Dual-Energy CT: A Phantom Study 
Markus M. Obmann, Chansik An, Michael A. Ohliger, Yuxin Sun, Zhen J. Wang, Benjamin M. Yeh.
3:10-3:20 pm  Motion resolved UTE based Pulmonary QSM 
Xucheng Zhu, Hongjiang Wei, Kevin M. Johnson, Scott K. Nagle, Wenwen Jiang, Joseph Cheng, Shreyas S. Vasanawala, Michael Lustig, Chunlei Liu, Peder E.Z. Larson.
3:20-3:30 pm  Highly Accelerated Breath-hold Steady-State Ferumoxytol Abdomen MRA using Compressed Sensing 
Chengcheng Zhu, Joseph Leach, Sinyeob Ahn, David Saloner, and Michael D Hope
3:30-3:40 pm  Aerosol Jet-Deposited Double Helix Wireless Resonant Markers for MRI Catheter Tracking 
Caroline D. Jordan, Bradford R. H. Thorne, Arjun Wadhwa, Sravani Kondapavulur, Vincent Fratello, Ron Watkins, Greig Scott, Alastair J. Martin, Xiaoliang Zhang, Mark W. Wilson, Steven W. Hetts
3:40-3:50 pm  Long-Term Volumetric Thermometry for Measurement of Diffuse Tissue Heating during MRgFUS Treatments 
Eugene Ozhinsky, Matthew Bucknor, and Viola Rieke
3:50-4:00 pm  Imaging Bone-Cartilage Interactions in the Hip Joint using [18F]-NaF PET-MRI 
Radhika Tibrewala M.Sc, Emma Bahroos M.Sc, Hatef Mehrebian PhD, Valentina Pedoia PhD, Sharmila Majumdar PhD
4:00-4:10 pm  Multi-modality in vivo imaging of cortical bone vasculature – Comparison of diabetes patients to healthy controls
Po-hung Wu, Matthew Gibbons, Sarah Foreman, Julio Carballido-Gamio, Misung Han, Roland Krug, Jing Liu, Thomas Link, Galateia Kazakia
4:10-4:20 pm  Automatic Hip Fracture Identification and Functional Classification with Deep Learning 
Kaiyang Cheng1, Justin D. Krogue MD2, Kevin Hwang MD2, Eugene Ozhinsky PhD1, Sharmila Majumdar PhD1, Valentina Pedoia PhD1, 1 - Department of Radiology and Biomedical Imaging (UCSF), 2 - Orthopedic Surgery (UCSF)
4:35-6:00 pm  Poster Session, Award Presentations, Bruce Hasegawa Award Presentation, and Catered Reception
Millberry Union
5:00 pm  Comments by Christopher P. Hess, MD PhD, Professor and Chair of the Department of Radiology and Biomedical Imaging; 
5:45 pm  Announcement of the Oral and Poster Presentation Awards

Poster Presentations

 #  Presenting Author  Abstract Title
 1  Adam Autry Comparison between 8- and 32-channel phased-array receive coils for in vivo hyperpolarized C-13 imaging of the human brain
 2  Karthik Gopalan Digitally Manufactured, Highly Conformal Receive Arrays
 3  Anna Moroz Remodeling of the cell surface proteome presents new opportunities for the treatment of RAS driven malignancies.
 4  Evan Kao Quantitative comparison of CFD and 4DMR in the transverse sinus of a pulsatile tinnitus patient
 5  Hardik Kothare Neural correlates of aberrant vocal motor control in Adductor Spasmodic Dysphonia
 6  Ella Jones Initial Experience of Dedicated Breast PET imaging of ER+ Breast Cancers Using [F-18]fluoroestradiol
 7  Dharshan Chandramohan Quantitative imaging of bone material analogues for PET/MRI phantoms
 8  Denis Beckford Vera Immuno-PET imaging of human tumor necrosis factor alpha in an transgenic mouse model of rheumatoid arthritis.
 9  Brian Chung First-in-Man Hyperpolarized [2-13C]Pyruvate MR Studies of Human Brain Metabolism
 10  Kristina Liu Towards Clinical Hyperpolarized 13C pH Imaging Using a New Bicarbonate Precursor
 11  David Korenchan Hyperpolarized In vivo pH Imaging Reveals Grade-Dependent Acidification in Prostate Cancer
 12  Wen Li The role of diffusion-weighted MRI in the prediction of response in I-SPY 2 TRIAL
 13  Elavarasan Subramani Magnetic resonance spectroscopy-based metabolic biomarkers of IDH1 mutant glioma response to temozolomide therapy
 14  Sivakami Avadiappan Characterization of Radiation Therapy Effects on Cerebral Vasculature in Pediatric Brain Tumor Survivors
 15  Pedro Maia Heterogeneity of Incipient Atrophy Patterns in Parkinson’s Disease.
 16  Lisa Wilmes Effect of image distortion and gradient nonlinearity corrections on breast tumor DTI metrics pre- and early-therapy
 17  Junnian Wei Profiling the surface proteome identifies actionable biology for TSC1 mutant cells beyond mTORC1 signaling
 18  Chang Cai COGNAC: A Novel Bayesian Scanning Algorithm for MEG/EEG imaging based on Covariance Partitioning
 19  Grace Jun 18F-Fluorocholine PETMR: Optimizing Injection Delay for Parathyroid Adenoma Localization
 20  Georgios Batsios PI3K/mTOR inhibition of IDH1 mutant glioma leads to reduced 2HG production that is associated with increased survival
 21  Alejandro Morales Martinez Weakly Supervised and Unsupervised Segmentation Deep Learning Models: Can we Overcome the Ground Truth?
 22  Chang Cai Evaluation of DSSP in MEG recordings from patients with intractable epilepsy and VNS
 23  Yung-Hua Wang Targeting iron metabolism in high grade glioma with 68Ga-citrate PET/MR
 24  Ning Zhao Exploiting the Labile Fe(II) Pool to Image Prostate Cancer with PET
 25  Yangjie Huang Measuring glucocorticoid receptor expression in vivo with PET.
 26  Jeremy Gordon Coil Combination Methods for Multi-Channel Hyperpolarized 13C MRI
 27  Abhejit Rajagopal Deep iterative-reconstruction algorithms for single-photon computed tomography (SPECT)
 28  Yao Liu the evolution of knee structural changes differs in subjects at risk for knee OA with and without HIV infection
 29  Céline Taglang Imaging tissue pH using chemical shift-based hyperpolarized 13C MRI probes
 30  Yutaka Natsuaki Motion-Robust and Efficient Radial TSE T2 Mapping with “Pseudo” Golden Ratio Reordering
 31  Shuyu Tang Metabolic Specific Imaging with Bolus tracking and Real-time B0/B1 calibration for Human Hyperpolarized 13C Imaging
 32  Jason Crane Automated Longitudinal Alignment and Visualization of Clinical Neurological MRI Exams
 33  Raven Smith 68Ga-PSMA PET/MRI: Determining ideal acquisition times to reduce noise and increase image quality
 34  Fayyaz Ahamed Assessment of intracellular lactate relaxation and production and efflux rates in cells using hyperpolarized 13C MR
 35  Brian Leahy MR Imaging of Vasculature within Cortical Bone Pores: A Validation Study
 36  Natalie Korn Rate of Hyperpolarized [1-13C] Pyruvate to Lactate Conversion Distinguishes High-Grade Prostate Cancer in Patients
 37  Anna Moroz A preclinical assessment of 89Zr-atezolizumab identifies a requirement for carrier added formulations not observed with 89Zr-C4.
 38  Leighton Hinkley Cortical dynamics during speech preparation in primary progressive aphasia
 39  Denis Beckford Vera A Personalized Predictive Tracer with Diagnostic and Therapeutic Potential
 40  Sinan Wang Development and validation of new hyperpolarized 13C magnetic resonance imaging probes targeting zinc metabolism
 41  Anna Moroz Targeting mTORC1 signaling to detect tuberous sclerosis complex and lymphangioleiomyomatosis with PET.
 42  Paula Alcaide Leon Pseudoprogression in GBM patients treated with HSP-peptide vaccine and chemoradiation
 43  Colin Yee Intravascular Gentamicin Filter for Reduction of Systemic Toxicities
 44  Justin Yuan Structural brain network properties and cognitive impairment in adolescents after radiation therapy
 45  Trevor Flynn Graph metrics of white matter connectomes in infants with CHD
 46  Silvia Schiro Diagnostic success rate of CT-guided deep bone biopsy in confirming clinical findings and imaging suspicious of bone infection
 47  Sarah Foreman Meniscal Damage but Not Cartilage Composition, Predict Accelerated Knee OA: Data from the Osteoarthritis Initiative
 48  Baptiste Hans A Densely Connected Convolutional Neural Network for Automatic Scoring of Articular Cartilage in Hip Osteoarthritis MRI
 49  Thomas Hayes Preparation of carbon-11-labeled surrogates of VX and Sarin: Divergent radiosynthesis of 11C-tracers
 50  Carly Demopoulos Global Alpha and Beta Band Functional Connectivity in Children with Autism and Children with Sensory Processing Dysfunction
 51  Henrik Haraldsson Reduction of Flow Jets following Lumbar Puncture in Patients with Pulsatile Tinnitus
 52  Keerthi Valluru Characterizing Pulsatile Tinnitus with venous etiology using 4D Flow MRI and in vitro patient-specific flow models
 53  Yan Wang Combined Deep Learning and Annular-like Shape Constrained Deformable Method for Fully Automatic Left Ventricle Segmentation
 54  Fadya Binyameen Automated Segmentation of Hip Muscles using Unsupervised Multi-Parametric Method
 55  Fredrik Strand Breast MRI: Correlation between the quantitative BPE of a single central slice and the whole-breast visual BI-RADS category
 56  Andrew Leynes PET/MRI joint estimation of attenuation and activity with deep learning-based uncertainty estimation

2017 Imaging Research Symposium

The 14th Annual Imaging Research Symposium

October 10, 2017

Symposium Program
12:00pm Registration & Poster Highlights Cole Hall


Opening Remarks

Sharmila Majumdar, PhD, Professor and Vice Chair for Research, Department of Radiology and Biomedical Imaging

1:10-2:30pm Oral Presentations (Session I)
An Vu, PhD: ‘Stimulus Locked K-space Shuffling (SILK) for Ultra-high Resolution fMRI’
Jae Ho Sohn, MD, MS: ‘Data-driven Lung Cancer Risk Stratification of Pulmonary Nodules in Chest CT using 3D Convolutional Neural Network’    
David Newitt, PhD ‘Concordance of Apparent Diffusion Coefficient Measurements across the NCI Quantitative Imaging Network’
Spencer Behr, MD: ‘First-in-Human Studies with CTT1057, a Novel F-18 PSMA PET in Prostate Cancer’
Iris Broce, PhD: ‘Immune-related Genetic Enrichment in Frontotemporal Dementia’
Yiran Chen: ‘A Metabolic Study of Hypoxic Ischemia during Mouse Brain Development using Hyperpolarized 13C’
Berk Norman: ‘Convolutional-Neural Networks For Knee Multi-Tissue Automatic Morphometry and Relaxometry’ 
2:20pm Melanie Morrison, PhD: ‘The Effects of Radiotherapy-Induced Vascular Injury on Cognitive Function in Children treated for Pediatric Brain Tumor’
2:30-3:00pm Break
3:00-4:30pm Oral Presentations (Session II)
Cyrus Manuel, MS: ‘Weakly Supervised Deep Feature Learning to Predict Aβ-positivity from Structural MR Brain Images'
Denis Beckford Vera, PhD: ‘Positron Emission Tomography Imaging of Human Tumor Necrosis Factor Alpha using Zirconium-89 Certoluzimab Pegol’
Jessie Lee: ‘Compact Ultrasound Applicator for Hyperthermia Treatment of the TRAMP Model with MR Thermometry in a 14T MRI Scanner’
Ella Jones, PhD: ‘Association between Dedicated Breast PET and MR imaging Features in Primary Invasive Breast Cancers’
Carly Demopoulos, PhD: ‘Auditory and Somatosensory Response in ASD: Evidence for Domain Specificity and Associations with Language’
Michael Samaan, PhD: ‘Abnormal Muscle Forces after Hip Arthroscopy are Related to Altered Cartilage Composition in FAI Patients’
Chin Hong Tan, PhD: ‘Polygenic Hazard Score: An Enrichment Marker for Alzheimer's Associated Amyloid and Tau Deposition’
Brice Tiret, PhD: ‘Hyperpolarized [1-13C] Pyruvate as a Biomarker for Treatment Monitoring in Lymphoma Murine Models’ 
4:30-6:00pm    Poster Session, Award Presentations, and Catered Reception
Millberry Union
4:45pm Presentation of the Hasegawa Award

Podium and Poster Presentation Awards

Closing Comments - Ronald L. Arenson, MD, Professor and Chair, Department of Radiology

and Biomedical Imaging


Poster List

1. The Impact of Scoring Coronary Artery Calcifications on Lung Cancer Screening CT on Distinct Populations
Ana Paula Santos Lima

2. Design and Validation of an iOS App in Tracking Performance During the 30-second Chair Stand Test and Stair Climb Test
Solomon Joseph

3. Hyperpolarized 13C MRSI Monitoring of Response to HDAC Inhibition in Glioblastoma
Marina Radoul

4. Simultaneous T1/T2 Mapping of Hyperpolarized 13C Compounds using the bSSFP Sequence    
Eugene Milshteyn

5. PI3K/mTOR Inhibition Leads to Reduction in 2HG Production and Cell Proliferation in IDH1 Mutant Cells
Georgios Batsios

6. Human Hyperpolarized C-13 MRI Using a Novel Echo-Planar Imaging (EPI) Approach
Jeremy Gordon

7. MR Thermometry-guided Ultrasound Hyperthermia of User-Defined Regions
Eugene Ozhinsky

8. Targeting TSC1 Driven Bladder Cancers with Antibodies to Upregulated and Functionally Important Cell-Surface Proteins
Junnian Wei

9. Suicidality in Depressed Adolescents: A Study of Neural Changes with a Mind-Body Intervention
Sarina  Bhandari

10. Quantitative Morphometric Evaluation of Subcortical Regions in Neurofibromatosis Type 1
Matt Barkovich

11. Tibiofemoral Kinematics is Associated with Biochemical Meniscal Alterations After ACL Reconstruction
Alexander Markes

12. Detection of Aggressive Prostate Cancer Using New Hyperpolarized 13C Magnetic Resonance Imaging Probes Targeting Zinc Metabolism
Sinan Wang

13. Improved Design and Validation Methods of a Chemofiltration Device In Vivo       
Colin Yee

14. Exploiting the Labile Fe(II) Pool to Image Prostate Cancer with PET
Yung-Hua Wang

15. Pulse Sequences for Preclinical In Vivo pH Imaging with Hyperpolarized [13C] Bicarbonate       
David Korenchan

16. Grey Matter Volume Changes in Adolescents Participating in a Meditation Training
Justin Yuan

17. Acetate Metabolism Towards Fatty Acids is Down-Regulated in IDH1 Mutant Glioma as Shown by 13C MRS
Chloe Najac

18. In Vivo Metabolic Imaging of Traumatic Brain Injury        
Caroline Guglielmetti

19. Using Machine Learning to Predict ChemoFilter Parameters for Clearance of Doxorubicin From Physiologic Solutions
Anna Vardapetyan

20. Clearance of Cisplatin from Physiologic Solutions with DNA-based ChemoFilter
Ayushi Gautam

21. Aerosol-Deposited Wireless Resonant Markers for Interventional MRI         
Caroline Jordan

22. Rapid 4C Body Composition Using Dual-Energy X-Ray Absorptiometry and Bioelectrical Impedance Analysis
Bennett Ng

23. Oral Cavity Numbing Reduces Sensorimotor Adaptation to Altered Auditory Feedback
Hardik Kothare

24. Distinct Spatiotemporal Patterns of Resting State Neuronal Synchrony in Alzheimer’s Disease Spectrum
Kamalini Ranasinghe

25. Speech Production Without the Vocal Tract
Megan Thompson

26. Automated Cortical Bone Vessel Identification on Contrast-Enhanced MRI Images       
Po-hung Wu

27. Dynamic Functional Brain Imprint of Post-traumatic Stress Disorder (PTSD) Subtypes in Task-free fMRI
Susanne Mueller

28. Altered Speech Production in Response to Transient Mid-Utterance Formant Perturbation     
Inez Raharjo

29. Quantification of Mammographic Masking in Digital Mammography to Predict Interval Cancer Risk
Benjamin Hinton

30. In Vivo Metabolism of Hyperpolarized Pyruvate in Human Brain Tumor Patients   
Daniele Mammoli

31. Application of Machine learning to Structural Connectome to Predict Improvement in Depressed Adolescents with CBT
Olga Tymofiyeva

32. Brain Metabolite Levels, Especially Glutamate, Affect Functional Connectivity in Alcohol Dependence
Donna Murray

33. Direct Pseudo CT Generation for Pelvis PET/MRI Attenuation Correction Using Deep Convolutional Neural Networks
Andrew Leynes

34. Picturing Individualized 3D Body Shape Change From Fat Loss and Muscle Gain: The Shape Up! Study
Markus Sommer

35. Synthetic Images From Cardiac T1 mapping and Automatic Segmentation for Myocardial Fibrosis Assessment
Yan Wang

36. Deep Learning for Identification and Quantification of Acute Intraparenchymal Hemorrhage on Head CT
Peter Chang

37. Imaging In Vivo Brain Glutathione Content with Hyperpolarized [1-13C] Dehydroascorbic Acid
Hecong Qin

38. A Longitudinal Analysis of Regional Brain Changes in Anti-NMDAR Encephalitis  
Ryan Michael Nillo

39. Functional Imaging Platform to Monitor Progression and Response to Therapy in a Pre-Clinical Model of BCBM
Alba Gonzalez Junca

40. Precision Imaging of Metastatic and Primary Brain Tumors After radiation with 18F-FDOPA PET-MRI is Feasible and Cost Effective
Mariam Aboian

41. Treatment Induced Plasticity of Motor and Language Networks in Patients with Brain Lesions
Nina Sardesh

42. An Advanced Post-Processing Algorithm to Improve Detectability of Brain Hemorrhages in Flat-Panel CT Images
Jay Yu

43. Hyperpolarized 13C-MRI Detects Early Tumor Response Following Knockout of the LDHA Gene in Prostate Cancer
Robert Bok

44. Novel Techniques for MR Metabolic Imaging using Hyperpolarized [2-13C]Pyruvate        
Brian Chung

45. The Neurobiology of Self-Agency During Reality Monitoring and Its Relation with Self-Agency During Speech Monitoring
Karuna Subramaniam

46. Characterizing Altered Glucose and Glutamine Metabolism of Castration-Resistant Prostate Cancer using High Resolution NMR
Jinny Sun

47. MRI and HR-pQCT Changes Correlate with Michigan Hand Outcome Questionnaire in Rheumatoid Arthritis
Ana Cruz

48. Efficient Method for Deuteration of 13C Labeled Substrates for T1 Prolongation in Hyperpolarized 13C MRI Spectroscopy
Celine Taglang

49. Synthesis and Evaluation of C-11 and F-18 VX and Sarin Surrogates to Assess Therapeutic Countermeasures
Thomas Hayes

50. Analysis of Associations Between Cartilage Morphology and Biochemistry after ACL Injury and Reconstruction
Ezinna Nnabue

51. Slice-selective Double Spin Echo Sequence for Dynamic C-13 Imaging        
Xucheng Zhu

52. Microscale DWI of Individual Fresh Prostate Biopsies at 14 T  
Jeremy Bancroft Brown

53. Metabolic Imaging of Rodent Placenta using Hyperpolarized 13C Pyruvate MRI   
Renuka Sriram

54. Correction of Geometric Image Distortion and Gradient Nonlinearity: Effects on DTI of Breast Cancer
Lisa Wilmes

55. Functional Connectivity Underlying Attentional Deficits in Children Born Preterm
Trevor Flynn

56. Multimodal Imaging of Chronic Tinnitus       
Leighton Hinkley

57. Distinguishing Inflammation in the Peripheral Zone of the Prostate by Multiparametric MRI
Natalie Korn

58. Hierarchical Multiscale Bayesian Algorithms for Robust MEG/EEG Source Reconstruction
Chang Cai

59. Selective Regional TSC1 Gene Expression in Tuberous Sclerosis Complex          
Yi Li

60. Approximating Ischemic Stroke Location and Abnormal Tissue Regions Through Subtracting NCCT and CTA Scans
Jeffrey Pyne

2016 Imaging Research Symposium

The 13th Annual Imaging Research Symposium

September 20, 2016

Symposium Program
12:30 pm Registration & Poster Highlights Cole Hall

1:00-1:10 pm

Opening Remarks

Sharmila Majumdar, PhD, Professor and Vice Chair for Research,
Department of Radiology and Biomedical Imaging

1:10-2:50 pm Oral Presentations (Session I)
1:10-1:20 pm

Five-minute Motion Robust High Resolution 3D Free-Breathing MR Pulmonary Imaging

Wenwen Jiang, Frank Ong, Kevin M. Johnson, Scott K Nagle,Thomas Hope, Michael Lustig, Peder E.Z. Larson

 1:20-1:30 pm

High coronary artery calcification in a lung cancer screening population and
Statin use

Lima APS, Kallianos K, Mukae K, Elicker BM, Hope MD, Naeger DN, Henry TS, Rao R, Ordovas KG.

1:30-1:40 pm

Developing ChemoFilter for Clearance of DNA Binding Drugs and
Chemotherapeutic Cocktails

Aboian MS, Yu J, Kuo W, Fisher J, Gautam A, Sze CH, Yang J, Chan J,
Lillaney PV, Jordan CD, Wilson DM, Patel AS, Wilson MW, Hetts SW.

 1:40-1:50 pm

Breast MRI Background Parenchymal Enhancement for Predicting Response
to Chemotherapy

Paul Kim, Wen Li, Roy Harnish, Cody McHargue, David C Newitt, Ella Jones,
Laura J Esserman, Bonnie N Joe, and Nola M Hylton

1:50-2:00 pm

Tau and Antecedent Amyloid Accumulation Rates in Asymptomatic and Early
Symptomatic Individuals

Duygu Tosun and Michael Weiner

2:00-2:10 pm

Induced high-gamma oscillations during speaking distinguish variants of primary progressive aphasia

Leighton B.N. Hinkley, Megan M. Cahill Thompson, Zachary A. Miller, Kamalini
Ranasinghe, Danielle Mizuiri, Coleman Garrett, Susanne Honma, Bruce Miller,
Keith Vossel, John F. Houde, Maria Luisa Gorno-Tempini, Srikantan S. Nagarajan

 2:10-2:20 pm    

DTI-based brain network changes in youth with training of attention and emotion regulation

Olga Tymofiyeva, Eva Henje Blom, Justin Yuan, Colm G. Connolly,
Tiffany C. Ho, Lisa Baldini, Trevor Flynn, Matthew D. Sacchet, Kaja Z. LeWinn,
Rebecca Dumont Walter, Tony T. Yang, Duan Xu

2:20-2:30 pm

Metabolic Profiling of Malignant Transformation and IDH-mutation in Diffuse Infiltrating Gliomas

Llewellyn Jalbert, Adam Elkhaled, Joanna J Phillips, Evan Neill, 
Marram P Olson, Mitchel S Berger, John Kurhanewicz, Sabrina Ronen,
Susan M Chang, and Sarah J Nelson

2:30-3:00 pm Coffee Break
3:00-4:20 pm Oral Presentations (Session II)
3:00-3:10 pm

In Vivo Imaging and Quantification of Grafted Stem Cells With SWIFT Pulse Sequence

Sergey Magnitsky, Djaudat Idiyatullin, Jinjin Zhang, Nancy Lane, Sharmila Majumdar

3:10-3:20 pm

Detection of Bacteria-specific metabolism using hyperpolarized 13C pyruvate

Renuka Sriram, Javier Villanueva-Meyer, Tiffany Kwak, Dave Korenchan, Oren
Rosenberg, John Kurhanewicz, Dave Wilson and Michael Ohliger

3:20-3:30 pm

PET imaging of infection using metabolic labeling of the bacterial cell wall

Villanueva-Meyer, Javier E., Mutch, Christopher A., Neumann, Kiel D.,
Ohliger, Michael A., Rosenberg, Oren S., Wilson, David M.

3:30-3:40 pm

Perfusion and Metabolic Imaging of Acute Kidney Injury

Celine Baligand*, Hecong Qin*, David Lovett, Jeremy Gordon, Joy Walker,
David Wilson, John Kurhanewicz, Zhen Jane Wang

3:40-3:50 pm

Dicarboxylic Acids as pH Sensors with Hyperpolarized 13C MR Spectroscopy

Korenchan, David E.; Taglang, Celine; Blecha, Joseph; Kurhanewicz, John;
Wilson, David M.; Flavell, Robert R.

3:50-4:00 pm

MRI and Biomechanics Topological Data Analysis for data-driven discovery in

Valentina Pedoia, Jenny Haefeli, Kazuhito Morioka, Hsiang-Ling Teng, Lorenzo
Nardo, Richard B. Souza, Adam Ferguson, Sharmila Majumdar

4:00-4:10 pm

Acceleration of 3D UTE Imaging to Quantify Temperature-Dependent T1
Changes in Cortical Bone

Misung Han, Wenwen Jiang, Eugene Ozhinsky, Roland Krug,
Peder EZ Larson, Viola Rieke

4:10-4:20 pm

Validity & Reliability of Pocket-size Ultrasound to Assess Distal-Radius
Fracture & Closed-Reduction

Brian C. Lau, Aaron Robertson, Nicolas Lee, Daria Motamedi

4:35-6:00 pm Poster Session, Award Presentations, and Catered Reception
Millberry Union
4:45 pm Presentation of the Hasegawa Award
5:45 pm    

Podium and Poster Presentation Awards

Closing Comments - Ronald L. Arenson, MD, Professor and Chair,
Department of Radiology and Biomedical Imaging

Poster Presentations

 #  Presenting Author  Abstract Title


 2  ana paula santos lima Impact of coronary calcium description on lung cancer screening CT

 3  Jinny Sun Metabolic profiling of androgen insensitive prostate cancer cells using high resolution NMR

 4  Lisa Wilmes Diffusion Tensor Imaging to Assess Breast Tumor Response to Neoadjuvant Chemotherapy

 5  Ana Paula Santos Lima Cardiac Magnetic Resonance strain analysis showing abnormalities in patients with aortic stenosis

 6  Loc Huynh Measuring mTOR activity in models of tuberous sclerosis complex with 89Zr-transferrin PET

 7  Madeline Hess 3D Hamming Window Filter Implementation for Spectroscopic MR Imaging in SIVIC

 8  Eugene Ozhinsky T2-based Temperature Monitoring in Bone Marrow for MR-guided Focused Ultrasound

 9  v s testing new forms

 10  Justin Yuan Test-retest reliability of DTI-based brain network measures in adolescents

 11  Jeremy Huang Differences in Variation of Hepatic ADC in HCV+ and HCV+/HIV+ Men with Similar Pathology

 12  Hsin-Yu Chen 3D Dynamic Hyperpolarized 13C-Pyruvate MR Metabolic Imaging of Human Prostate Cancer

 13  Caroline Jordan Preclinical Feasibility Study of MR-guided Embolectomy using Wireless Resonant Markers

 14  Yu Zhang Rates of progressive white matter degeneration and gray matter loss differ in FTLD subtypes

 15  Valerie Caroll Differential Transport of [11C]Vitamin C and [11C]Dehydroascorbic Acid Redox Pair.

 16  Caroline Guglielmetti Imaging myelin with ultrashort-echo time (UTE) in a Multiple Sclerosis model on a clinical 7T system

 17  Joy Yeh Changes in Structural Networks after Radiation Therapy in Patients with Brain Tumors

 18  Olga Starobinets Sparse Prostate Cancers Can be Detected on Multiparametric MRI

 19  Charles TRUILLET Imaging the Glucocorticoid Receptor in the Context of Castration-Resistant Prostate Cancer


 21  Kimberly Kallianos 24-hour Coronary CTA in the ED: Increased scanner volume and increased efficiency.

 22  Cyrus Raji Insights from Population Based Neuroimaging Regarding Modifiable Risk Factors for Alzheimer’s Dementia

 23  Hosung Kim Fetal Brain Volume May Predict Neonatal Brain Injury in Patients with Congenital Heart Disease

 24  Jack Lambert An image-domain, contrast material extraction method for Dual-Energy CT

 25  Yung-Hua Wang Development of radiolabeled artificial substrates to target important cancer metabolic pathways

 26  Benjamin Hinton A Measure of Regional Mammographic Masking Based on the CDMAM Phantom

 27  Nathan Poulin EM Simulations of a Loopless RF coil at 3T with and w/out extremely high dielectric coating

 28  Peng Cao Magnetization-prepared, Multi-contrast, Volumetric and Rapid Gradient Echo Imaging at 7T

 29  Kiel Neumann A Novel Radiosynthesis and in vivo characterization of an Acetylcholinesterase PET Tracer

 30  Jesus Avila Energy dependence of water and lipid calibration materials for three-compartment breast imaging

 31  Priya Nimbalkar Contrast Agents for MRI Cell Tracking With Positive Contrast

 32  Paul Kim Automated versus Manual Segmentation for Measuring Background Parenchymal Enhancement on Breast MRI

 33  Stojan Maleschlijski Predicting malignant transformations in recurrent low-grade gliomas using ex vivo spectroscopic data

 34  Sravani Kondapavulur Optimization of an endovascular magnetic filter for maximized capture of magnetic nanoparticles

 35  Eugene Milshteyn Using a Local Low Rank plus Sparse Reconstruction to Accelerate 3D bSSFP Hyperpolarized 13C Imaging

 36  Matthew Parker Development of radiolabeled artificial receptors to target important cancer signaling pathways

 37  Ella Jones MammiPET imaging of early response to neoadjuvant chemotherapy in breast cancer

 38  Charles Truillet Applying transferrin based PET to study oncogene signaling in cancer: from bench to bedside

 39  Cyrus Raji Relationship of Subtle Cognitive Deficits and White Matter Microstructure on DTI in Pediatric TBI

 40  Jessica Gibbs Comparison of whole tumor and single slice ROIs for measuring ADC in breast cancer

 41  Chloé Najac Detection of inflammatory cell function using 13C MRS of hyperpolarized [6-13C]-arginine

 42  Kamalini Ranasinghe Altered sensorimotor integration in feedback control of vocal pitch in Alzheimer’s Disease

 43  Pavithra Viswanath MCT down-regulation contributes to reduced hyperpolarized lactate production in mutant IDH1 cells

 44  Bennett Ng Body shape and fat distribution from DXA predicts metabolic syndrome across sexes and ethnicities

 45  Ilwoo Park Hyperpolarized Pyruvate Differentiates Distinct Molecular Phenotypes in Pediatric Brainstem Glioma

 46  Wen Li Effect of MRI contrast thresholds for prediction of NACT response in breast cancer

 47  Jeremy Gordon Improving Accuracy in Hyperpolarized ADC Mapping: Exploring the Impact of Slice-Profile Effects

 48  Khaled Jami PET Imaging of Tumor PD-L1 Expression with 89Zr-Labeled Anti-PD-L1 Antibodies

 49  David Korenchan Chemical Exchange Effects on Hyperpolarized 13C-Bicarbonate MRS Imaging

 50  Rutwik Shah Estimation of the probability of an osseous metastasis using CT size and density measurements

 51  Andrew Leynes Pseudo-CT Image Generation Using Combined Dixon and Zero Echo-time (ZTE) MRI

2015 Imaging Research Symposium

The 12th Annual Imaging Research Symposium

October 21, 2015

Note that links to speaker presentation abstracts may be accessed by UCSF employees with a Radiology password.
 12:00 pm  Complimentary Registration & Research Interest Group (RIG) Powerpoints
Cole Hall

 1:00-1:10 pm  Opening Remarks

Sharmila Majumdar, PhD,
Professor and Vice Chair, Research, UCSF Department of Radiology and Biomedical Imaging

 1:10-2:50 pm  Oral Presentations (Session I)
Moderators: Michael Evans, PhD, and Roland Krug, PhD
 1:10-1:20 pm  Associations between Gait Kinetic Variables and Patellofemoral Cartilage T1ρ and T2 Relaxation Time 
Hsiang-Ling Teng, Nathaniel Calixto, Thomas Link, Sharmila Majumdar , Richard Souza
 1:20-1:30 pm  Kinect Body Composition: Assessing Clinical Metabolic Health Indices using 3D Optical Images 
Bennett K. Ng, Benjamin J. Hinton, Jesus I. Avila, Bo Fan, Leila Kazemi, Eboni Stephens, Viva W. Tai, Caitlin Sheets, Alka Kanaya, John A. Shepherd
 1:30-1:40 pm  Longitudinal Bone Quality Assessment in Patients with Type-2 Diabetes by HR-pQCT 
Pasco C, Dinh N, Link T, Heilmeier U, Kazakia G
 1:40-1:50 pm  Caged [18F]-FDG Glycosylamines for Imaging Acidic Tumor Microenvironments 
Robert R. Flavell, Charles Truillet, Melanie K. Regan, Tanushree Ganguly, Joseph E. Blecha, John Kurhanewicz, Henry F. VanBrocklin, Kayvan R. Keshari, Christopher J. Chang, Michael J. Evans, David M. Wilson
 1:50-2:00 pm  Noninvasive Measurement of PI3K Pathway Signaling in GBM and Prostate Models 
Charles Truillet, Sergio Wong, John T. Cunningham, Davide Ruggero, Jason S. Lewis, Michael J. Evans
 2:00-2:10 pm  Tissue Classification for PET/MR MR-based Attenuation Correction Using Zero-echo Time (ZTE) MRI 
Andrew Leynes, Peder Larson
 2:10-2:20 pm  Detection of Pulmonary Nodules by UTE Sequences in Oncology Patients using a PET/MR System 
Nicholas S Burris, Kevin M Johnson, Peder E Z Larson, Michael D Hope, Scott K. Nagle, Spencer C Behr and Thomas A Hope
 2:20-2:30 pm  High resolution DWI to evaluate breast tumor treatment response: Association of ADC changes with pCR 
Lisa J Wilmes, Wei-Ching Lo, Wen Li, David C Newitt, Suchandrima Banerjee, Evelyn Proctor, Emine U Saritas, Ajit Shankaranarayanan, Nola M Hylton
 2:30-3:00 pm  Coffee Break
Nobel Wall outside Cole Hall
Research Interest Group (RIG) Powerpoints will be shown in Cole Hall during the break

 3:00-4:20 pm  Oral Presentations (Session II)
Moderators: Peder Larson, PhD, and Susanne Mueller, MD
 3:00-3:10 pm  Triple-Negative Glioma: MR Features & Molecular Markers in an Aggressive Subtype of Low-Grade Glioma 

Javier Villanueva Meyer, MD; Byung Se Choi, MD; Matthew Wood, MD, PhD; Tarik Tihan, MD, PhD; Soonmee Cha, MD
 3:10-3:20 pm  Hyperpolarized 13C MRSI is a better predictor of survival than tumor size in treated GBM models 
Marina Radoul, Myriam M Chaumeil, Pia Eriksson, Aaron S Wang, Joanna J Phillips, Sabrina M Ronen
 3:20-3:30 pm  Hyperpolarized 13C MRSI can detect neuroinflammation in vivo in a Multiple Sclerosis murine model 
Caroline Guglielmetti, Chloe Najac, Annemie Van der Linden, Sabrina M. Ronen, Myriam M. Chaumeil
 3:30-3:40 pm  In vivo Measurement of Renal Redox Capacity And Renal Perfusion in a Model of Chronic Kidney Disease 
Celine Baligand, David Lovett, Lalita Uttarwar, Rajeev Mahimkar, David Wilson, John Kurhanewicz, Jane Wang
 3:40-3:50 pm  Novel RF Coil Design to Incorporate Parallel Imaging into 13C MRSI for Human Subjects at 3T 
Natalie Korn, John Kurhanewicz, Susan Noworolski
 3:50-4:00 pm  Real-time MR Thermometry Feedback Control for Prostate Hyperthermia with a Commercial HIFU System 
Eugene Ozhinsky, Vasant A. Salgaonkar, Chris J. Diederich, and Viola Rieke
 4:00-4:10 pm  A Novel Approach to Segment Neonatal Brain Tissues and Measure Cortical Folding in MRI with Motion 
Hosung Kim, Romir Maheshwary, A. James Barkovich and Duan Xu
 4:10-4:20 pm  Patient-Specific CFD Analysis of Flow Patters in the Jugular Vein 
Evan Kao, Sarah Kefayati, Farshid Faraji, Matthew Amans, Van Halbach, David Saloner
 4:35-6:00 pm  Poster Session, Award Presentations, and Catered Reception
Millberry Union

 4:45 pm  Presentation of the Bruce Hasegawa Award
David Saloner, PhD, Professor in Residence, Dept of Radiology and Biomedical Imaging

 5:45 pm  Podium and Poster Presentation Awards - Xiaojuan Li, PhD, Associate Professor in Residence, Dept of Radiology and Biomedical Imaging

Closing Remarks
Ronald L. Arenson, MD, Professor and Chair, UCSF Department of Radiology and Biomedical Imaging