Thomas Link, MD, PhD

Professor, & Chief of Musculoskeletal Imaging
Clinical Director of MQIR
Co-Director, Musculoskeletal RIG
Director, T32 Program
Professor in Residence

Biography

Thomas M. Link, MD, PhD, is Chief of the Musculoskeletal Imaging Section and Clinical Director of the Musculoskeletal and Quantitative Imaging Research (MQIR) Group in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Dr. Link completed his medical residency in Muenster, Germany. He performed a research fellowship at the University of California, San Francisco in 1996 and was a Visiting Associate Professor at UCSF from 1999-2001. Before joining the Department of Radiology and Biomedical Imaging in 2003 he was a Vice-Chair of the Department of Radiology at the Technical University of Munich.

As Clinical Director of the Musculoskeletal and Quantitative Imaging Research (MQIR) Group, Dr. Link’s main interest is translational research. He wants to provide clinical background to basic science researchers, assessing clinical feasibility of research projects and to apply new imaging techniques in clinical studies.

Dr. Link’s research program in MQIR has five main focuses: imaging of osteoporosis, particularly developing new imaging techniques for assessment of bone quality and density, application on new imaging techniques for the clinical assessment of osteoarthritis, cartilage and prevention of cartilage degeneration, new imaging sequences for musculoskeletal imaging at high field, and MR guided high intensity focused ultrasound for treatment of osseous abnormalities.

Dr. Link has published extensively with more than 400 peer-reviewed articles, 48 review articles, 47 book chapters, and 3 books.

Expertise:
Musculoskeletal Radiology

Specialty:
Bone tumors and interventional procedures, osteoporosis and osteoarthritis

Professional Interests:
New techniques for musculoskeletal imaging, osteoporosis, osteoarthritis, cartilage imaging, high field musculoskeletal MRI at 3.0 and 7.0T, MR-guided focused ultrasound

Education and Training:
• Medical School: Johannes-Gutenberg University, Mainz, Germany
• Medical School: Groote Schuur Hospital University of Cape Town, Cape Town, RSA
• Internship: City Hospital Idar-Oberstein, Teaching Hospital of the Johannes-Gutenberg, Mainz Germany
• Residency: Department of Radiology Center for Rheumatic Diseases of the State of Rheinland-Pfalz, Bad Kreuznach, Germany
• Residency: Department of Radiology, KKH Hellersen, Teaching Hospital of the University of Bonn, Germany
• Residency: Department of Radiology, University Hospital, Muenster
• Fellowship: University of California, San Francisco Department of Radiology
• Doctor of Philosophy: University Hospital, Muenster Department of Radiology
• Board Examination in Radiology (including Radiation Therapy), Muenster, Germany
• Board Examination in Diagnostic Radiology, Muenster, Germany
• ECFMG (USMLE, Step 1 and 2)
• Temporary California License
• USMLE Step 3
• DEA License
• Permanent California License
• Fluoroscopy Supervisor License
• Equivalence certification of Doctor of Philosophy (Ph.D.) degree in Medicine (for German qualifications) by Center for Educational Documentation, Boston
• Diagnostic Radiology Core Exam, American Board of Radiology
• Board Certification Diagnostic Radiology, American Board of Radiology

Education

M.D., 1987 - School of Medicine, Johannes Gutenberg University

Honors and Awards

Senior Fellow Award, International Society for Magnetic Resonance in Medicine, 2017
Outstanding Reviewer Award, Osteoarthritis&Cartilage, 2017
Distinguished Investigator Award, Academy of Radiology Research, 2016
Certificate of Special Distinction, Skeletal Radiology, 2014
Editor-in-Chief, Current Radiology Reports, 2012
George J. Davies - James A. Gould, Excellence in Clinical Inquiry Award, The Journal of Othopaedic and Sports Physical Therapy, 2012
Editor’s Recognition Award with Distinction, Radiology, 2011
The Founder's Lecturer, International Skeletal Society, Washington, 2009
Editors Recognition, European Journal of Radiology, 2007-2008
Plenary Lecturer, World Congress on Osteoarthritis, Prague. Czech Republic, 2007
Top Cited Award, Osteoarthritis and Cartilage, 2006-2008
Appointed Chairman, Osteoporosis Group of the European Society of Skeletal Radiology (ESSR), 2006
Teaching Award, Medical School of the Technical University of Munich, Germany, 2000
Caffey Award, Society of Pediatric Radiology, 1997

Publications

Link TM. Editorial comment: the future of compositional MRI for cartilage. Eur Radiol. 2018 Apr 30.
Teng HL, Pedoia V, Link TM, Majumdar S, Souza RB. Local associations between knee cartilage T1? and T2 relaxation times and patellofemoral joint stress during walking: A voxel-based relaxometry analysis. Knee. 2018 Apr 19.
Link TM, Li X. Establishing compositional MRI of cartilage as a biomarker for clinical practice. Osteoarthritis Cartilage. 2018 Mar 15.
Guimaraes JB, Facchetti L, Schwaiger BJ, Gersing AS, Li X, Link TM. Natural evolution of popliteomeniscal fascicle tears over 2 years and its association with lateral articular knee cartilage degeneration in patients with traumatic anterior cruciate ligament tear. Eur Radiol. 2018 Feb 23.
Joseph GB, McCulloch CE, Nevitt MC, Neumann J, Gersing AS, Kretzschmar M, Schwaiger BJ, Lynch JA, Heilmeier U, Lane NE, Link TM. Tool for osteoarthritis risk prediction (TOARP) over 8 years using baseline clinical data, X-ray, and MRI: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2017 Nov 16.
Guimaraes JB, Nevitt MC, McCulloch CE, Schwaiger BJ, Gersing AS, Facchetti L, Bucknor MD, Chanchek N, Liu F, Joseph GB, Link TM. Association of weight change with progression of meniscal intrasubstance degeneration over 48 months: Data from the Osteoarthritis Initiative. Eur Radiol. 2017 Oct 06.
Shimizu T, Choi HJ, Heilmeier U, Tanaka M, Burghardt AJ, Gong J, Chanchek N, Link TM, Graf J, Imboden JB, Li X. Assessment of 3-month changes in bone microstructure under anti-TNFa therapy in patients with rheumatoid arthritis using high-resolution peripheral quantitative computed tomography (HR-pQCT). Arthritis Res Ther. 2017 Oct 04; 19(1):222.
Schwaiger BJ, Mbapte Wamba J, Gersing AS, Nevitt MC, Facchetti L, McCulloch CE, Link TM. Hyperintense signal alteration in the suprapatellar fat pad on MRI is associated with degeneration of the patellofemoral joint over 48 months: data from the Osteoarthritis Initiative. Skeletal Radiol. 2018 Mar; 47(3):329-339.
Hofmann FC, Neumann J, Heilmeier U, Joseph GB, Nevitt MC, McCulloch CE, Link TM. Conservatively treated knee injury is associated with knee cartilage matrix degeneration measured with MRI-based T2 relaxation times: data from the osteoarthritis initiative. Skeletal Radiol. 2018 Jan; 47(1):93-106.
Samaan MA, Pedoia V, Zhang AL, Gallo MC, Link TM, Souza RB, Majumdar S. A novel mr-based method for detection of cartilage delamination in femoroacetabular impingement patients. J Orthop Res. 2018 Mar; 36(3):971-978.
Chanchek N, Gersing AS, Schwaiger BJ, Nevitt MC, Neumann J, Joseph GB, Lane NE, Zarnowski J, Hofmann FC, Heilmeier U, McCulloch CE, Link TM. Association of diabetes mellitus and biochemical knee cartilage composition assessed by T2 relaxation time measurements: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2018 Feb; 47(2):380-390.
Holmes MG, Foss E, Joseph G, Foye A, Beckett B, Motamedi D, Youngren J, Thomas GV, Huang J, Aggarwal R, Alumkal JJ, Beer TM, Small EJ, Link TM. CT-Guided Bone Biopsies in Metastatic Castration-Resistant Prostate Cancer: Factors Predictive of Maximum Tumor Yield. J Vasc Interv Radiol. 2017 Aug; 28(8):1073-1081.e1.
Morgan TA, Piper SL, Lattanza LL, Goldstein RB, Link T, Motamedi D. Distal Forearm Fracture Open Reduction-Internal Fixation: Sonographic Detection of Hardware Malalignment and Associated Tendon Injuries Missed by Radiography. J Ultrasound Med. 2017 Oct; 36(10):2173-2177.
Gersing AS, Schwaiger BJ, Nevitt MC, Joseph GB, Chanchek N, Guimaraes JB, Mbapte Wamba J, Facchetti L, McCulloch CE, Link TM. Is Weight Loss Associated with Less Progression of Changes in Knee Articular Cartilage among Obese and Overweight Patients as Assessed with MR Imaging over 48 Months? Data from the Osteoarthritis Initiative. Radiology. 2017 08; 284(2):508-520.
Schwaiger BJ, Kopperdahl DL, Nardo L, Facchetti L, Gersing AS, Neumann J, Lee KJ, Keaveny TM, Link TM. Vertebral and femoral bone mineral density and bone strength in prostate cancer patients assessed in phantomless PET/CT examinations. Bone. 2017 Aug; 101:62-69.
Joseph GB, McCulloch CE, Nevitt MC, Gersing AS, Schwaiger BJ, Kretzschmar M, Heilmeier U, Link TM. Medial femur T2 Z-scores predict the probability of knee structural worsening over 4-8 years: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2017 Oct; 46(4):1128-1136.
Samaan MA, Facchetti L, Pedoia V, Tanaka MS, Link TM, Souza RB, Ma CB, Li X. Cyclops lesions are associated with altered gait patterns and medial knee joint cartilage degeneration at 1 year after ACL-reconstruction. J Orthop Res. 2017 10; 35(10):2275-2281.
Link TM, Neumann J, Li X. Prestructural cartilage assessment using MRI. J Magn Reson Imaging. 2017 Apr; 45(4):949-965.
Samaan MA, Schwaiger BJ, Gallo MC, Sada K, Link TM, Zhang AL, Majumdar S, Souza RB. Joint Loading in the Sagittal Plane During Gait Is Associated With Hip Joint Abnormalities in Patients With Femoroacetabular Impingement. Am J Sports Med. 2017 Mar; 45(4):810-818.
Facchetti L, Schwaiger BJ, Gersing AS, Guimaraes JB, Nardo L, Majumdar S, Ma BC, Link TM, Li X. Cyclops lesions detected by MRI are frequent findings after ACL surgical reconstruction but do not impact clinical outcome over 2 years. Eur Radiol. 2017 Aug; 27(8):3499-3508.
Gong J, Pedoia V, Facchetti L, Link TM, Ma CB, Li X. Bone marrow edema-like lesions (BMELs) are associated with higher T1? and T2 values of cartilage in anterior cruciate ligament (ACL)-reconstructed knees: a longitudinal study. Quant Imaging Med Surg. 2016 Dec; 6(6):661-670.
Guimaraes JB, Facchetti L, Schwaiger BJ, Gersing AS, Majumdar S, Ma BC, Li X, Link TM. Evolution of Intrameniscal Signal-Intensity Alterations Detected on MRI Over 24 Months in Patients With Traumatic Anterior Cruciate Ligament Tear. AJR Am J Roentgenol. 2017 Feb; 208(2):386-392.
Link TM, Heilmeier U. Bone Quality-Beyond Bone Mineral Density. Semin Musculoskelet Radiol. 2016 Jul; 20(3):269-278.
Samaan MA, Schwaiger BJ, Gallo MC, Link TM, Zhang AL, Majumdar S, Souza RB. Abnormal Joint Moment Distributions and Functional Performance During Sit-to-Stand in Femoroacetabular Impingement Patients. PM R. 2017 Jun; 9(6):563-570.
Gersing AS, Schwaiger BJ, Heilmeier U, Joseph GB, Facchetti L, Kretzschmar M, Lynch JA, McCulloch CE, Nevitt MC, Steinbach LS, Link TM. Evaluation of Chondrocalcinosis and Associated Knee Joint Degeneration Using MR Imaging: Data from the Osteoarthritis Initiative. Eur Radiol. 2017 Jun; 27(6):2497-2506.
Heilmeier U, Hackl M, Skalicky S, Weilner S, Schroeder F, Vierlinger K, Patsch JM, Baum T, Oberbauer E, Lobach I, Burghardt AJ, Schwartz AV, Grillari J, Link TM. Serum miRNA Signatures Are Indicative of Skeletal Fractures in Postmenopausal Women With and Without Type 2 Diabetes and Influence Osteogenic and Adipogenic Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells In Vitro. J Bone Miner Res. 2016 Dec; 31(12):2173-2192.
Ku E, Pedoia V, Tanaka M, Heilmeier U, Imboden J, Graf J, Link T, Li X. Evaluating radiocarpal cartilage matrix changes 3-months after anti-TNF treatment for rheumatoid arthritis using MR T1? imaging. J Magn Reson Imaging. 2017 05; 45(5):1514-1522.
Pedoia V, Su F, Amano K, Li Q, McCulloch CE, Souza RB, Link TM, Ma BC, Li X. Analysis of the articular cartilage T1? and T2 relaxation times changes after ACL reconstruction in injured and contralateral knees and relationships with bone shape. J Orthop Res. 2017 03; 35(3):707-717.
Trivedi H, Link TM, O'Donnell RJ, Horvai AE, Motamedi D. Multiple hereditary exostoses: A pseudoaneurysm masquerading as tumor. J Radiol Case Rep. 2016 Aug; 10(8):50-59.
Gutierrez LB, Link T, Chaganti K, Motamedi D. Arterial calcification due to CD73 deficiency (ACDC): imaging manifestations of ectopic mineralization. Skeletal Radiol. 2016 Nov; 45(11):1583-7.
Burke C, Link T, O'Donnell RJ, Cho SJ, Motamedi D. Giant Cell Tumor of Bone: Documented Progression over 4 Years from Its Origin at the Metaphysis to the Articular Surface. Case Rep Radiol. 2016; 2016:9786925.
Leeman JJ, Motamedi D, Wildman-Tobriner B, O'Donnell RJ, Link TM. Intra-articular osteoid osteoma at the femoral trochlea treated with osteochondral autograft transplantation. J Radiol Case Rep. 2016 Jun; 10(6):22-29.
Patel R, Eltgroth M, Souza R, Zhang CA, Majumdar S, Link TM, Motamedi D. Loaded versus unloaded magnetic resonance imaging (MRI) of the knee: Effect on meniscus extrusion in healthy volunteers and patients with osteoarthritis. Eur J Radiol Open. 2016; 3:100-7.
Samaan MA, Zhang AL, Gallo MC, Schwaiger BJ, Link TM, Souza RB, Majumdar S. Quantitative magnetic resonance arthrography in patients with femoroacetabular impingement. J Magn Reson Imaging. 2016 Dec; 44(6):1539-1545.
Schwaiger BJ, Gersing AS, Mbapte Wamba J, Nevitt MC, McCulloch CE, Link TM. Can Signal Abnormalities Detected with MR Imaging in Knee Articular Cartilage Be Used to Predict Development of Morphologic Cartilage Defects? 48-Month Data from the Osteoarthritis Initiative. Radiology. 2016 10; 281(1):158-67.
Schwaiger BJ, Gersing AS, Lee S, Nardo L, Samaan MA, Souza RB, Link TM, Majumdar S. Longitudinal assessment of MRI in hip osteoarthritis using SHOMRI and correlation with clinical progression. Semin Arthritis Rheum. 2016 06; 45(6):648-55.
Joseph GB, Hou SW, Nardo L, Heilmeier U, Nevitt MC, McCulloch CE, Link TM. MRI findings associated with development of incident knee pain over 48 months: data from the osteoarthritis initiative. Skeletal Radiol. 2016 May; 45(5):653-60.
Pedoia V, Majumdar S, Link TM. Segmentation of joint and musculoskeletal tissue in the study of arthritis. MAGMA. 2016 Apr; 29(2):207-21.
Heilmeier U, Youm J, Torabi S, Link TM. Osteoporosis Imaging in the Geriatric Patient. Curr Radiol Rep. 2016 Apr; 4(4).
Gersing AS, Link TM. Imaging of Osteoarthritis in Geriatric Patients. Curr Radiol Rep. 2016 Jan; 4(1).
Wang A, Pedoia V, Su F, Abramson E, Kretzschmar M, Nardo L, Link TM, McCulloch CE, Jin C, Ma CB, Li X. MR T1? and T2 of meniscus after acute anterior cruciate ligament injuries. Osteoarthritis Cartilage. 2016 Apr; 24(4):631-9.
Liu J, Pedoia V, Heilmeier U, Ku E, Su F, Khanna S, Imboden J, Graf J, Link T, Li X. High-temporospatial-resolution dynamic contrast-enhanced (DCE) wrist MRI with variable-density pseudo-random circular Cartesian undersampling (CIRCUS) acquisition: evaluation of perfusion in rheumatoid arthritis patients. NMR Biomed. 2016 Jan; 29(1):15-23.
Nardo L, Han M, Kretzschmar M, Guindani M, Koch K, Vail T, Krug R, Link TM. Erratum to: Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla. Skeletal Radiol. 2015 Nov; 44(11):1617.
Hackney LA, Lee MH, Joseph GB, Vail TP, Link TM. Subchondral insufficiency fractures of the femoral head: associated imaging findings and predictors of clinical progression. Eur Radiol. 2016 Jun; 26(6):1929-41.
Link TM, Schwaiger BJ, Zhang AL. Regional Articular Cartilage Abnormalities of the Hip. AJR Am J Roentgenol. 2015 Sep; 205(3):502-12.
Plett SK, Hackney LA, Heilmeier U, Nardo L, Yu A, Zhang CA, Link TM. Femoral condyle insufficiency fractures: associated clinical and morphological findings and impact on outcome. Skeletal Radiol. 2015 Dec; 44(12):1785-94.
Calixto NE, Kumar D, Subburaj K, Singh J, Schooler J, Nardo L, Li X, Souza RB, Link TM, Majumdar S. Zonal differences in meniscus MR relaxation times in response to in vivo static loading in knee osteoarthritis. J Orthop Res. 2016 Feb; 34(2):249-61.
Samaan MA, Teng HL, Kumar D, Lee S, Link TM, Majumdar S, Souza RB. Acetabular cartilage defects cause altered hip and knee joint coordination variability during gait. Clin Biomech (Bristol, Avon). 2015 Dec; 30(10):1202-9.
Kumar D, Souza RB, Subburaj K, MacLeod TD, Singh J, Calixto NE, Nardo L, Link TM, Li X, Lane NE, Majumdar S. Are There Sex Differences in Knee Cartilage Composition and Walking Mechanics in Healthy and Osteoarthritis Populations? Clin Orthop Relat Res. 2015 Aug; 473(8):2548-58.
Nardo L, Parimi N, Liu F, Lee S, Jungmann PM, Nevitt MC, Link TM, Lane NE. Femoroacetabular Impingement: Prevalent and Often Asymptomatic in Older Men: The Osteoporotic Fractures in Men Study. Clin Orthop Relat Res. 2015 Aug; 473(8):2578-86.
Nardo L, Han M, Kretzschmar M, Kretschmar M, Guindani M, Koch K, Vail T, Krug R, Link TM. Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla. Skeletal Radiol. 2015 Nov; 44(11):1609-16.
Teng HL, MacLeod TD, Link TM, Majumdar S, Souza RB. Higher Knee Flexion Moment During the Second Half of the Stance Phase of Gait Is Associated With the Progression of Osteoarthritis of the Patellofemoral Joint on Magnetic Resonance Imaging. J Orthop Sports Phys Ther. 2015 Sep; 45(9):656-64.
Guha A, Wyatt C, Karampinos DC, Nardo L, Link TM, Majumdar S. Spatial variations in magnetic resonance-based diffusion of articular cartilage in knee osteoarthritis. Magn Reson Imaging. 2015 Nov; 33(9):1051-1058.
Link TM. Radiology of Osteoporosis. Can Assoc Radiol J. 2016 Feb; 67(1):28-40.
Lee S, Lucas RM, Lansdown DA, Nardo L, Lai A, Link TM, Krug R, Ma CB. Magnetic resonance rotator cuff fat fraction and its relationship with tendon tear severity and subject characteristics. J Shoulder Elbow Surg. 2015 Sep; 24(9):1442-51.
Teng HL, MacLeod TD, Kumar D, Link TM, Majumdar S, Souza RB. Individuals with isolated patellofemoral joint osteoarthritis exhibit higher mechanical loading at the knee during the second half of the stance phase. Clin Biomech (Bristol, Avon). 2015 May; 30(4):383-90.
Kretzschmar M, Nardo L, Han MM, Heilmeier U, Sam C, Joseph GB, Koch KM, Krug R, Link TM. Metal artefact suppression at 3 T MRI: comparison of MAVRIC-SL with conventional fast spin echo sequences in patients with Hip joint arthroplasty. Eur Radiol. 2015 Aug; 25(8):2403-11.
Kumar D, Wyatt C, Chiba K, Lee S, Nardo L, Link TM, Majumdar S, Souza RB. Anatomic correlates of reduced hip extension during walking in individuals with mild-moderate radiographic hip osteoarthritis. J Orthop Res. 2015 Apr; 33(4):527-34.
Lance V, Heilmeier UR, Joseph GB, Steinbach L, Ma B, Link TM. MR imaging characteristics and clinical symptoms related to displaced meniscal flap tears. Skeletal Radiol. 2015 Mar; 44(3):375-84.
Kumar D, Souza RB, Singh J, Calixto NE, Nardo L, Link TM, Li X, Majumdar S. Physical activity and spatial differences in medial knee T1rho and t2 relaxation times in knee osteoarthritis. J Orthop Sports Phys Ther. 2014 Dec; 44(12):964-72.
Bucknor MD, Rieke V, Seo Y, Horvai AE, Hawkins RA, Majumdar S, Link TM, Saeed M. Bone remodeling after MR imaging-guided high-intensity focused ultrasound ablation: evaluation with MR imaging, CT, Na(18)F-PET, and histopathologic examination in a swine model. Radiology. 2015 Feb; 274(2):387-94.
Lee CH, Srikhum W, Burghardt AJ, Virayavanich W, Imboden JB, Link TM, Li X. Correlation of structural abnormalities of the wrist and metacarpophalangeal joints evaluated by high-resolution peripheral quantitative computed tomography, 3 Tesla magnetic resonance imaging and conventional radiographs in rheumatoid arthritis. Int J Rheum Dis. 2015 Jul; 18(6):628-39.
Lee S, Nardo L, Kumar D, Wyatt CR, Souza RB, Lynch J, McCulloch CE, Majumdar S, Lane NE, Link TM. Scoring hip osteoarthritis with MRI (SHOMRI): A whole joint osteoarthritis evaluation system. J Magn Reson Imaging. 2015 Jun; 41(6):1549-57.
Gupta R, Virayavanich W, Kuo D, Su F, Link T, Ma B, Li X. MR T(1)? quantification of cartilage focal lesions in acutely injured knees: correlation with arthroscopic evaluation. Magn Reson Imaging. 2014 Dec; 32(10):1290-6.
Teruel JR, Burghardt AJ, Rivoire J, Srikhum W, Noworolski SM, Link TM, Imboden JB, Li X. Bone structure and perfusion quantification of bone marrow edema pattern in the wrist of patients with rheumatoid arthritis: a multimodality study. J Rheumatol. 2014 Sep; 41(9):1766-73.
Zhang AL, Gates CH, Link TM, Ma CB. Abnormal origins of the long head of the biceps tendon can lead to rotator cuff pathology: a report of two cases. Skeletal Radiol. 2014 Nov; 43(11):1621-6.
Liebl H, Heilmeier U, Lee S, Nardo L, Patsch J, Schuppert C, Han M, Rondak IC, Banerjee S, Koch K, Link TM, Krug R. In vitro assessment of knee MRI in the presence of metal implants comparing MAVRIC-SL and conventional fast spin echo sequences at 1.5 and 3 T field strength. J Magn Reson Imaging. 2015 May; 41(5):1291-9.
Link TM, Lang TF. Axial QCT: clinical applications and new developments. J Clin Densitom. 2014 Oct-Dec; 17(4):438-48.
Serebrakian AT, Poulos T, Liebl H, Joseph GB, Lai A, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Weight loss over 48 months is associated with reduced progression of cartilage T2 relaxation time values: data from the osteoarthritis initiative. J Magn Reson Imaging. 2015 May; 41(5):1272-1280.
Kazakia GJ, Tjong W, Nirody JA, Burghardt AJ, Carballido-Gamio J, Patsch JM, Link T, Feeley BT, Ma CB. The influence of disuse on bone microstructure and mechanics assessed by HR-pQCT. Bone. 2014 Jun; 63:132-40.
Kumar D, Dillon A, Nardo L, Link TM, Majumdar S, Souza RB. Differences in the association of hip cartilage lesions and cam-type femoroacetabular impingement with movement patterns: a preliminary study. PM R. 2014 Aug; 6(8):681-9.
Alizai H, Virayavanich W, Joseph GB, Nardo L, Liu F, Liebl H, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Cartilage lesion score: comparison of a quantitative assessment score with established semiquantitative MR scoring systems. Radiology. 2014 May; 271(2):479-87.
Subburaj K, Souza RB, Wyman BT, Le Graverand-Gastineau MP, Li X, Link TM, Majumdar S. Changes in MR relaxation times of the meniscus with acute loading: an in vivo pilot study in knee osteoarthritis. J Magn Reson Imaging. 2015 Feb; 41(2):536-43.
Jungmann PM, Liu F, Link TM. What has imaging contributed to the epidemiological understanding of osteoarthritis? Skeletal Radiol. 2014 Mar; 43(3):271-5.
Bauer JS, Sidorenko I, Mueller D, Baum T, Issever AS, Eckstein F, Rummeny EJ, Link TM, Raeth CW. Prediction of bone strength by µCT and MDCT-based finite-element-models: how much spatial resolution is needed? Eur J Radiol. 2014 Jan; 83(1):e36-42.
Bucknor MD, Rieke V, Do L, Majumdar S, Link TM, Saeed M. MRI-guided high-intensity focused ultrasound ablation of bone: evaluation of acute findings with MR and CT imaging in a swine model. J Magn Reson Imaging. 2014 Nov; 40(5):1174-80.
Kumar D, Subburaj K, Lin W, Karampinos DC, McCulloch CE, Li X, Link TM, Souza RB, Majumdar S. Quadriceps and hamstrings morphology is related to walking mechanics and knee cartilage MRI relaxation times in young adults. J Orthop Sports Phys Ther. 2013 Dec; 43(12):881-90.
Solomon DA, Antonescu CR, Link TM, O'Donnell RJ, Folpe AL, Horvai AE. Hemosiderotic fibrolipomatous tumor, not an entirely benign entity. Am J Surg Pathol. 2013 Oct; 37(10):1627-30.
Nardo L, Karampinos DC, Lansdown DA, Carballido-Gamio J, Lee S, Maroldi R, Ma CB, Link TM, Krug R. Quantitative assessment of fat infiltration in the rotator cuff muscles using water-fat MRI. J Magn Reson Imaging. 2014 May; 39(5):1178-85.
Jungmann PM, Kraus MS, Nardo L, Liebl H, Alizai H, Joseph GB, Liu F, Lynch J, McCulloch CE, Nevitt MC, Link TM. T(2) relaxation time measurements are limited in monitoring progression, once advanced cartilage defects at the knee occur: longitudinal data from the osteoarthritis initiative. J Magn Reson Imaging. 2013 Dec; 38(6):1415-24.
Patsch JM, Zulliger MA, Vilayphou N, Samelson EJ, Cejka D, Diarra D, Berzaczy G, Burghardt AJ, Link TM, Weber M, Loewe C. Quantification of lower leg arterial calcifications by high-resolution peripheral quantitative computed tomography. Bone. 2014 Jan; 58:42-7.
Patsch JM, Li X, Baum T, Yap SP, Karampinos DC, Schwartz AV, Link TM. Bone marrow fat composition as a novel imaging biomarker in postmenopausal women with prevalent fragility fractures. J Bone Miner Res. 2013 Aug; 28(8):1721-8.
Bucknor MD, Gross AJ, Link TM. Voriconazole-induced periostitis in two post-transplant patients. J Radiol Case Rep. 2013 Aug; 7(8):10-7.
Burghardt AJ, Lee CH, Kuo D, Majumdar S, Imboden JB, Link TM, Li X. Quantitative in vivo HR-pQCT imaging of 3D wrist and metacarpophalangeal joint space width in rheumatoid arthritis. Ann Biomed Eng. 2013 Dec; 41(12):2553-64.
Nardo L, Sandman DN, Virayavanich W, Zhang L, Souza RB, Steinbach L, Guindani M, Link TM. Bone marrow changes related to disuse. Eur Radiol. 2013 Dec; 23(12):3422-31.
Jungmann PM, Tham SC, Liebl H, Nevitt MC, McCulloch CE, Lynch J, Link TM. Association of trochlear dysplasia with degenerative abnormalities in the knee: data from the Osteoarthritis Initiative. Skeletal Radiol. 2013 Oct; 42(10):1383-92.
Subburaj K, Valentinitsch A, Dillon AB, Joseph GB, Li X, Link TM, Vail TP, Majumdar S. Regional variations in MR relaxation of hip joint cartilage in subjects with and without femoralacetabular impingement. Magn Reson Imaging. 2013 Sep; 31(7):1129-36.
Chundru R, Baum T, Nardo L, Nevitt MC, Lynch J, McCulloch CE, Link TM. Focal knee lesions in knee pairs of asymptomatic and symptomatic subjects with OA risk factors--data from the Osteoarthritis Initiative. Eur J Radiol. 2013 Aug; 82(8):e367-73.
Srikhum W, Virayavanich W, Burghardt AJ, Yu A, Link TM, Imboden JB, Li X. Quantitative and semiquantitative bone erosion assessment on high-resolution peripheral quantitative computed tomography in rheumatoid arthritis. J Rheumatol. 2013 Apr; 40(4):408-16.
Patsch JM, Burghardt AJ, Yap SP, Baum T, Schwartz AV, Joseph GB, Link TM. Increased cortical porosity in type 2 diabetic postmenopausal women with fragility fractures. J Bone Miner Res. 2013 Feb; 28(2):313-24.
Theologis AA, Haughom B, Liang F, Zhang Y, Majumdar S, Link TM, Ma CB, Li X. Comparison of T1rho relaxation times between ACL-reconstructed knees and contralateral uninjured knees. Knee Surg Sports Traumatol Arthrosc. 2014 Feb; 22(2):298-307.
Baum T, Joseph GB, Nardo L, Virayavanich W, Arulanandan A, Alizai H, Carballido-Gamio J, Nevitt MC, Lynch J, McCulloch CE, Link TM. Correlation of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with body mass index: thirty-six-month followup data from a longitudinal, observational multicenter study. Arthritis Care Res (Hoboken). 2013 Jan; 65(1):23-33.
Ries MD, Link TM. Monitoring and risk of progression of osteolysis after total hip arthroplasty. Instr Course Lect. 2013; 62:207-14.
Srikhum W, Nardo L, Karampinos DC, Melkus G, Poulos T, Steinbach LS, Link TM. Magnetic resonance imaging of ankle tendon pathology: benefits of additional axial short-tau inversion recovery imaging to reduce magic angle effects. Skeletal Radiol. 2013 Apr; 42(4):499-510.
Karampinos DC, Melkus G, Shepherd TM, Banerjee S, Saritas EU, Shankaranarayanan A, Hess CP, Link TM, Dillon WP, Majumdar S. Diffusion tensor imaging and T2 relaxometry of bilateral lumbar nerve roots: feasibility of in-plane imaging. NMR Biomed. 2013 Jun; 26(6):630-7.
Ries MD, Link TM. Monitoring and risk of progression of osteolysis after total hip arthroplasty. J Bone Joint Surg Am. 2012 Nov 21; 94(22):2097-105.
Souza RB, Feeley BT, Zarins ZA, Link TM, Li X, Majumdar S. T1rho MRI relaxation in knee OA subjects with varying sizes of cartilage lesions. Knee. 2013 Mar; 20(2):113-9.
Jungmann PM, Li X, Nardo L, Subburaj K, Lin W, Ma CB, Majumdar S, Link TM. Do cartilage repair procedures prevent degenerative meniscus changes?: longitudinal t1? and morphological evaluation with 3.0-T MRI. Am J Sports Med. 2012 Dec; 40(12):2700-8.
Valentinitsch A, Karampinos DC, Alizai H, Subburaj K, Kumar D, Link TM, Majumdar S. Automated unsupervised multi-parametric classification of adipose tissue depots in skeletal muscle. J Magn Reson Imaging. 2013 Apr; 37(4):917-27.
Nardo L, Alizai H, Virayavanich W, Liu F, Hernandez A, Lynch JA, Nevitt MC, McCulloch CE, Lane NE, Link TM. Lumbosacral transitional vertebrae: association with low back pain. Radiology. 2012 Nov; 265(2):497-503.
Stehling C, Souza RB, Hellio Le Graverand MP, Wyman BT, Li X, Majumdar S, Link TM. Loading of the knee during 3.0T MRI is associated with significantly increased medial meniscus extrusion in mild and moderate osteoarthritis. Eur J Radiol. 2012 Aug; 81(8):1839-45.
Subburaj K, Kumar D, Souza RB, Alizai H, Li X, Link TM, Majumdar S. The acute effect of running on knee articular cartilage and meniscus magnetic resonance relaxation times in young healthy adults. Am J Sports Med. 2012 Sep; 40(9):2134-41.
Link TM. Osteoporosis imaging: state of the art and advanced imaging. Radiology. 2012 Apr; 263(1):3-17.
Alizai H, Nardo L, Karampinos DC, Joseph GB, Yap SP, Baum T, Krug R, Majumdar S, Link TM. Comparison of clinical semi-quantitative assessment of muscle fat infiltration with quantitative assessment using chemical shift-based water/fat separation in MR studies of the calf of post-menopausal women. Eur Radiol. 2012 Jul; 22(7):1592-600.
Souza RB, Baum T, Wu S, Feeley BT, Kadel N, Li X, Link TM, Majumdar S. Effects of unloading on knee articular cartilage T1rho and T2 magnetic resonance imaging relaxation times: a case series. J Orthop Sports Phys Ther. 2012 Jun; 42(6):511-20.
Hovis KK, Alizai H, Tham SC, Souza RB, Nevitt MC, McCulloch CE, Link TM. Non-traumatic anterior cruciate ligament abnormalities and their relationship to osteoarthritis using morphological grading and cartilage T2 relaxation times: data from the Osteoarthritis Initiative (OAI). Skeletal Radiol. 2012 Nov; 41(11):1435-43.
Baum T, Joseph GB, Arulanandan A, Nardo L, Virayavanich W, Carballido-Gamio J, Nevitt MC, Lynch J, McCulloch CE, Link TM. Association of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with knee pain: data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2012 Feb; 64(2):248-55.
Zuo J, Joseph GB, Li X, Link TM, Hu SS, Berven SH, Kurhanewitz J, Majumdar S. In vivo intervertebral disc characterization using magnetic resonance spectroscopy and T1? imaging: association with discography and Oswestry Disability Index and Short Form-36 Health Survey. Spine (Phila Pa 1976). 2012 Feb 01; 37(3):214-21.
Karampinos DC, Yu H, Shimakawa A, Link TM, Majumdar S. Chemical shift-based water/fat separation in the presence of susceptibility-induced fat resonance shift. Magn Reson Med. 2012 Nov; 68(5):1495-505.
Prasad AP, George V, Porzig A, Horvai AE, Gross A, Shoback D, Link TM. Progressive craniofacial bone loss after cosmetic surgery at the forehead. Skeletal Radiol. 2012 Apr; 41(4):477-81.
Karampinos DC, Baum T, Nardo L, Alizai H, Yu H, Carballido-Gamio J, Yap SP, Shimakawa A, Link TM, Majumdar S. Characterization of the regional distribution of skeletal muscle adipose tissue in type 2 diabetes using chemical shift-based water/fat separation. J Magn Reson Imaging. 2012 Apr; 35(4):899-907.
Karampinos DC, Banerjee S, King KF, Link TM, Majumdar S. Considerations in high-resolution skeletal muscle diffusion tensor imaging using single-shot echo planar imaging with stimulated-echo preparation and sensitivity encoding. NMR Biomed. 2012 May; 25(5):766-78.
Baum T, Stehling C, Joseph GB, Carballido-Gamio J, Schwaiger BJ, Müller-Höcker C, Nevitt MC, Lynch J, McCulloch CE, Link TM. Changes in knee cartilage T2 values over 24 months in subjects with and without risk factors for knee osteoarthritis and their association with focal knee lesions at baseline: data from the osteoarthritis initiative. J Magn Reson Imaging. 2012 Feb; 35(2):370-8.
Li X, Yu A, Virayavanich W, Noworolski SM, Link TM, Imboden J. Quantitative characterization of bone marrow edema pattern in rheumatoid arthritis using 3 Tesla MRI. J Magn Reson Imaging. 2012 Jan; 35(1):211-7.
Majumdar S, Link TM, Steinbach LS, Hu S, Kurhanewicz J. Diagnostic tools and imaging methods in intervertebral disk degeneration. Orthop Clin North Am. 2011 Oct; 42(4):501-11, viii.
Joseph GB, Baum T, Carballido-Gamio J, Nardo L, Virayavanich W, Alizai H, Lynch JA, McCulloch CE, Majumdar S, Link TM. Texture analysis of cartilage T2 maps: individuals with risk factors for OA have higher and more heterogeneous knee cartilage MR T2 compared to normal controls--data from the osteoarthritis initiative. Arthritis Res Ther. 2011; 13(5):R153.
Pan J, Pialat JB, Joseph T, Kuo D, Joseph GB, Nevitt MC, Link TM. Knee cartilage T2 characteristics and evolution in relation to morphologic abnormalities detected at 3-T MR imaging: a longitudinal study of the normal control cohort from the Osteoarthritis Initiative. Radiology. 2011 Nov; 261(2):507-15.
Laberge MA, Baum T, Virayavanich W, Nardo L, Nevitt MC, Lynch J, McCulloch CE, Link TM. Obesity increases the prevalence and severity of focal knee abnormalities diagnosed using 3T MRI in middle-aged subjects--data from the Osteoarthritis Initiative. Skeletal Radiol. 2012 Jun; 41(6):633-41.
Baum T, Yap SP, Karampinos DC, Nardo L, Kuo D, Burghardt AJ, Masharani UB, Schwartz AV, Li X, Link TM. Does vertebral bone marrow fat content correlate with abdominal adipose tissue, lumbar spine bone mineral density, and blood biomarkers in women with type 2 diabetes mellitus? J Magn Reson Imaging. 2012 Jan; 35(1):117-24.
Burghardt AJ, Link TM, Majumdar S. High-resolution computed tomography for clinical imaging of bone microarchitecture. Clin Orthop Relat Res. 2011 Aug; 469(8):2179-93.
Krug R, Larson PE, Wang C, Burghardt AJ, Kelley DA, Link TM, Zhang X, Vigneron DB, Majumdar S. Ultrashort echo time MRI of cortical bone at 7 tesla field strength: a feasibility study. J Magn Reson Imaging. 2011 Sep; 34(3):691-5.
Link TM, Li X. Bone marrow changes in osteoarthritis. Semin Musculoskelet Radiol. 2011 Jul; 15(3):238-46.
Virayavanich W, Ringler MD, Chin CT, Baum T, Giaconi JC, O'Donnell RJ, Horvai AE, Jones KD, Link TM. CT-guided biopsy of bone and soft-tissue lesions: role of on-site immediate cytologic evaluation. J Vasc Interv Radiol. 2011 Jul; 22(7):1024-30.
Stahl R, Jain SK, Lutz J, Wyman BT, Le Graverand-Gastineau MP, Vignon E, Majumdar S, Link TM. Osteoarthritis of the knee at 3.0 T: comparison of a quantitative and a semi-quantitative score for the assessment of the extent of cartilage lesion and bone marrow edema pattern in a 24-month longitudinal study. Skeletal Radiol. 2011 Oct; 40(10):1315-27.
Giaconi JC, Link TM, Vail TP, Fisher Z, Hong R, Singh R, Steinbach LS. Morbidity of direct MR arthrography. AJR Am J Roentgenol. 2011 Apr; 196(4):868-74.
Li X, Kuo D, Schafer AL, Porzig A, Link TM, Black D, Schwartz AV. Quantification of vertebral bone marrow fat content using 3 Tesla MR spectroscopy: reproducibility, vertebral variation, and applications in osteoporosis. J Magn Reson Imaging. 2011 Apr; 33(4):974-9.
Cotofana S, Eckstein F, Wirth W, Souza RB, Li X, Wyman B, Hellio-Le Graverand MP, Link T, Majumdar S. In vivo measures of cartilage deformation: patterns in healthy and osteoarthritic female knees using 3T MR imaging. Eur Radiol. 2011 Jun; 21(6):1127-35.
Karampinos DC, Yu H, Shimakawa A, Link TM, Majumdar S. T1-corrected fat quantification using chemical shift-based water/fat separation: application to skeletal muscle. Magn Reson Med. 2011 Nov; 66(5):1312-26.
Sode M, Burghardt AJ, Pialat JB, Link TM, Majumdar S. Quantitative characterization of subject motion in HR-pQCT images of the distal radius and tibia. Bone. 2011 Jun 01; 48(6):1291-7.
Tham SC, Horvai AE, Link T, Steinbach L. Soft tissue mass at the infrascapular fossa. Skeletal Radiol. 2011 Jan; 40(1):105-6, 123-4.
Li X, Kuo D, Theologis A, Carballido-Gamio J, Stehling C, Link TM, Ma CB, Majumdar S. Cartilage in anterior cruciate ligament-reconstructed knees: MR imaging T1{rho} and T2--initial experience with 1-year follow-up. Radiology. 2011 Feb; 258(2):505-14.
Li X, Cheng J, Lin K, Saadat E, Bolbos RI, Jobke B, Ries MD, Horvai A, Link TM, Majumdar S. Quantitative MRI using T1? and T2 in human osteoarthritic cartilage specimens: correlation with biochemical measurements and histology. Magn Reson Imaging. 2011 Apr; 29(3):324-34.
Kazakia GJ, Burghardt AJ, Link TM, Majumdar S. Variations in morphological and biomechanical indices at the distal radius in subjects with identical BMD. J Biomech. 2011 Jan 11; 44(2):257-66.
Folkesson J, Goldenstein J, Carballido-Gamio J, Kazakia G, Burghardt AJ, Rodriguez A, Krug R, de Papp AE, Link TM, Majumdar S. Longitudinal evaluation of the effects of alendronate on MRI bone microarchitecture in postmenopausal osteopenic women. Bone. 2011 Mar 01; 48(3):611-21.
Rodríguez-Soto AE, Fritscher KD, Schuler B, Issever AS, Roth T, Kamelger F, Kammerlander C, Blauth M, Schubert R, Link TM. Texture analysis, bone mineral density, and cortical thickness of the proximal femur: fracture risk prediction. J Comput Assist Tomogr. 2010 Nov-Dec; 34(6):949-57.
Stehling C, Luke A, Stahl R, Baum T, Joseph G, Pan J, Link TM. Meniscal T1rho and T2 measured with 3.0T MRI increases directly after running a marathon. Skeletal Radiol. 2011 Jun; 40(6):725-35.
Burghardt AJ, Issever AS, Schwartz AV, Davis KA, Masharani U, Majumdar S, Link TM. High-resolution peripheral quantitative computed tomographic imaging of cortical and trabecular bone microarchitecture in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab. 2010 Nov; 95(11):5045-55.
Virayavanich W, Singh R, O'Donnell RJ, Horvai AE, Goldsby RE, Link TM. Osteoid osteoma of the femur in a 7-month-old infant treated with radiofrequency ablation. Skeletal Radiol. 2010 Nov; 39(11):1145-9.
Issever AS, Link TM, Newitt D, Munoz T, Majumdar S. Interrelationships between 3-T-MRI-derived cortical and trabecular bone structure parameters and quantitative-computed-tomography-derivedbone mineral density. Magn Reson Imaging. 2010 Nov; 28(9):1299-305.
Luke AC, Stehling C, Stahl R, Li X, Kay T, Takamoto S, Ma B, Majumdar S, Link T. High-field magnetic resonance imaging assessment of articular cartilage before and after marathon running: does long-distance running lead to cartilage damage? Am J Sports Med. 2010 Nov; 38(11):2273-80.
Link TM. The Founder's Lecture 2009: advances in imaging of osteoporosis and osteoarthritis. Skeletal Radiol. 2010 Oct; 39(10):943-55.
Burghardt AJ, Kazakia GJ, Sode M, de Papp AE, Link TM, Majumdar S. A longitudinal HR-pQCT study of alendronate treatment in postmenopausal women with low bone density: Relations among density, cortical and trabecular microarchitecture, biomechanics, and bone turnover. J Bone Miner Res. 2010 Dec; 25(12):2558-71.
Damilakis J, Adams JE, Guglielmi G, Link TM. Radiation exposure in X-ray-based imaging techniques used in osteoporosis. Eur Radiol. 2010 Nov; 20(11):2707-14.
Burghardt AJ, Kazakia GJ, Ramachandran S, Link TM, Majumdar S. Age- and gender-related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibia. J Bone Miner Res. 2010 May; 25(5):983-93.
Krug R, Burghardt AJ, Majumdar S, Link TM. High-resolution imaging techniques for the assessment of osteoporosis. Radiol Clin North Am. 2010 May; 48(3):601-21.
Blumenkrantz G, Zuo J, Li X, Kornak J, Link TM, Majumdar S. In vivo 3.0-tesla magnetic resonance T1rho and T2 relaxation mapping in subjects with intervertebral disc degeneration and clinical symptoms. Magn Reson Med. 2010 May; 63(5):1193-200.
Tham SC, Horvai AE, Link T, Steinbach L. Soft tissue mass at the infrascapular fossa. Skeletal Radiol. 2010 Apr 15.
Tham SC, Horvai AE, Link T, Steinbach L. Soft tissue mass at the infrascapular fossa. Skeletal Radiol. 2010 Apr 14.
Ristow O, Stehling C, Krug R, Steinbach L, Sabo G, Ambekar A, Huber M, Link TM. Isotropic 3-dimensional fast spin echo imaging versus standard 2-dimensional imaging at 3.0 T of the knee: artificial cartilage and meniscal lesions in a porcine model. J Comput Assist Tomogr. 2010 Mar-Apr; 34(2):260-9.
Zhao J, Li X, Bolbos RI, Link TM, Majumdar S. Longitudinal assessment of bone marrow edema-like lesions and cartilage degeneration in osteoarthritis using 3 T MR T1rho quantification. Skeletal Radiol. 2010 Jun; 39(6):523-31.
Sode M, Burghardt AJ, Kazakia GJ, Link TM, Majumdar S. Regional variations of gender-specific and age-related differences in trabecular bone structure of the distal radius and tibia. Bone. 2010 Jun; 46(6):1652-60.
Carballido-Gamio J, Blumenkrantz G, Lynch JA, Link TM, Majumdar S. Longitudinal analysis of MRI T(2) knee cartilage laminar organization in a subset of patients from the osteoarthritis initiative. Magn Reson Med. 2010 Feb; 63(2):465-72.
Link TM. MR imaging in osteoarthritis: hardware, coils, and sequences. Magn Reson Imaging Clin N Am. 2010 Feb; 18(1):95-110.
Folkesson J, Carballido-Gamio J, Eckstein F, Link TM, Majumdar S. Local bone enhancement fuzzy clustering for segmentation of MR trabecular bone images. Med Phys. 2010 Jan; 37(1):295-302.
Stehling C, Liebl H, Krug R, Lane NE, Nevitt MC, Lynch J, McCulloch CE, Link TM. Patellar cartilage: T2 values and morphologic abnormalities at 3.0-T MR imaging in relation to physical activity in asymptomatic subjects from the osteoarthritis initiative. Radiology. 2010 Feb; 254(2):509-20.
Zuo J, Saadat E, Romero A, Loo K, Li X, Link TM, Kurhanewicz J, Majumdar S. Assessment of intervertebral disc degeneration with magnetic resonance single-voxel spectroscopy. Magn Reson Med. 2009 Nov; 62(5):1140-6.
Krug R, Stehling C, Kelley DA, Majumdar S, Link TM. Imaging of the musculoskeletal system in vivo using ultra-high field magnetic resonance at 7 T. Invest Radiol. 2009 Sep; 44(9):613-8.
Issever AS, Link TM, Kentenich M, Rogalla P, Burghardt AJ, Kazakia GJ, Majumdar S, Diederichs G. Assessment of trabecular bone structure using MDCT: comparison of 64- and 320-slice CT using HR-pQCT as the reference standard. Eur Radiol. 2010 Feb; 20(2):458-68.
Bauer JS, Link TM. Advances in osteoporosis imaging. Eur J Radiol. 2009 Sep; 71(3):440-9.
Link TM. MR imaging in osteoarthritis: hardware, coils, and sequences. Radiol Clin North Am. 2009 Jul; 47(4):617-32.
Li X, Pai A, Blumenkrantz G, Carballido-Gamio J, Link T, Ma B, Ries M, Majumdar S. Spatial distribution and relationship of T1rho and T2 relaxation times in knee cartilage with osteoarthritis. Magn Reson Med. 2009 Jun; 61(6):1310-8.
Daldrup-Link HE, Mohanty A, Cuenod C, Pichler B, Link T. New perspectives on bone marrow contrast agents and molecular imaging. Semin Musculoskelet Radiol. 2009 Jun; 13(2):145-56.
Wong S, Steinbach L, Zhao J, Stehling C, Ma CB, Link TM. Comparative study of imaging at 3.0 T versus 1.5 T of the knee. Skeletal Radiol. 2009 Aug; 38(8):761-9.
Folkesson J, Krug R, Goldenstein J, Issever AS, Fang C, Link TM, Majumdar S. Evaluation of correction methods for coil-induced intensity inhomogeneities and their influence on trabecular bone structure parameters from MR images. Med Phys. 2009 Apr; 36(4):1267-74.
Zhao J, Krug R, Xu D, Lu Y, Link TM. MRI of the spine: image quality and normal-neoplastic bone marrow contrast at 3 T versus 1.5 T. AJR Am J Roentgenol. 2009 Apr; 192(4):873-80.
Stahl R, Krug R, Kelley DA, Zuo J, Ma CB, Majumdar S, Link TM. Assessment of cartilage-dedicated sequences at ultra-high-field MRI: comparison of imaging performance and diagnostic confidence between 3.0 and 7.0 T with respect to osteoarthritis-induced changes at the knee joint. Skeletal Radiol. 2009 Aug; 38(8):771-83.
Guglielmi G, Adams J, Link TM. Quantitative ultrasound in the assessment of skeletal status. Eur Radiol. 2009 Aug; 19(8):1837-48.
Link TM. Correlations between joint morphology and pain and between magnetic resonance imaging, histology, and micro-computed tomography. J Bone Joint Surg Am. 2009 Feb; 91 Suppl 1:30-2.
Carballido-Gamio J, Krug R, Huber MB, Hyun B, Eckstein F, Majumdar S, Link TM. Geodesic topological analysis of trabecular bone microarchitecture from high-spatial resolution magnetic resonance images. Magn Reson Med. 2009 Feb; 61(2):448-56.
Zhao J, Link TM. MRI in degenerative arthritides: structural and clinical aspects. Ann N Y Acad Sci. 2009 Feb; 1154:115-35.
Ristow O, Steinbach L, Sabo G, Krug R, Huber M, Rauscher I, Ma B, Link TM. Isotropic 3D fast spin-echo imaging versus standard 2D imaging at 3.0 T of the knee--image quality and diagnostic performance. Eur Radiol. 2009 May; 19(5):1263-72.
Bolbos RI, Ma CB, Link TM, Majumdar S, Li X. In vivo T1rho quantitative assessment of knee cartilage after anterior cruciate ligament injury using 3 Tesla magnetic resonance imaging. Invest Radiol. 2008 Nov; 43(11):782-8.
Rauscher I, Stahl R, Cheng J, Li X, Huber MB, Luke A, Majumdar S, Link TM. Meniscal measurements of T1rho and T2 at MR imaging in healthy subjects and patients with osteoarthritis. Radiology. 2008 Nov; 249(2):591-600.
Cabarrus MC, Ambekar A, Lu Y, Link TM. MRI and CT of insufficiency fractures of the pelvis and the proximal femur. AJR Am J Roentgenol. 2008 Oct; 191(4):995-1001.
Blumenfeld J, Studholme C, Carballido-Gamio J, Carpenter D, Link TM, Majumdar S. Three-dimensional image registration of MR proximal femur images for the analysis of trabecular bone parameters. Med Phys. 2008 Oct; 35(10):4630-9.
Link TM. In vivo quantification of cortical bone water with ultrashort echo-time MR imaging: a new parameter to measure bone quality? Radiology. 2008 Sep; 248(3):705-6.
Stahl R, Luke A, Li X, Carballido-Gamio J, Ma CB, Majumdar S, Link TM. T1rho, T2 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients--a 3.0-Tesla MRI study. Eur Radiol. 2009 Jan; 19(1):132-43.
Li X, Ma BC, Bolbos RI, Stahl R, Lozano J, Zuo J, Lin K, Link TM, Safran M, Majumdar S. Quantitative assessment of bone marrow edema-like lesion and overlying cartilage in knees with osteoarthritis and anterior cruciate ligament tear using MR imaging and spectroscopic imaging at 3 Tesla. J Magn Reson Imaging. 2008 Aug; 28(2):453-61.
Carballido-Gamio J, Link TM, Li X, Han ET, Krug R, Ries MD, Majumdar S. Feasibility and reproducibility of relaxometry, morphometric, and geometrical measurements of the hip joint with magnetic resonance imaging at 3T. J Magn Reson Imaging. 2008 Jul; 28(1):227-35.
Carballido-Gamio J, Link TM, Majumdar S. New techniques for cartilage magnetic resonance imaging relaxation time analysis: texture analysis of flattened cartilage and localized intra- and inter-subject comparisons. Magn Reson Med. 2008 Jun; 59(6):1472-7.
Saadat E, Jobke B, Chu B, Lu Y, Cheng J, Li X, Ries MD, Majumdar S, Link TM. Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference. Eur Radiol. 2008 Oct; 18(10):2292-302.
Stahl R, Luke A, Ma CB, Krug R, Steinbach L, Majumdar S, Link TM. Prevalence of pathologic findings in asymptomatic knees of marathon runners before and after a competition in comparison with physically active subjects-a 3.0 T magnetic resonance imaging study. Skeletal Radiol. 2008 Jul; 37(7):627-38.
Huber MB, Carballido-Gamio J, Bauer JS, Baum T, Eckstein F, Lochmüller EM, Majumdar S, Link TM. Proximal femur specimens: automated 3D trabecular bone mineral density analysis at multidetector CT--correlation with biomechanical strength measurement. Radiology. 2008 May; 247(2):472-81.
Müller D, Bauer JS, Zeile M, Rummeny EJ, Link TM. Significance of sagittal reformations in routine thoracic and abdominal multislice CT studies for detecting osteoporotic fractures and other spine abnormalities. Eur Radiol. 2008 Aug; 18(8):1696-702.
Bolbos RI, Zuo J, Banerjee S, Link TM, Ma CB, Li X, Majumdar S. Relationship between trabecular bone structure and articular cartilage morphology and relaxation times in early OA of the knee joint using parallel MRI at 3 T. Osteoarthritis Cartilage. 2008 Oct; 16(10):1150-9.
Kazakia GJ, Hyun B, Burghardt AJ, Krug R, Newitt DC, de Papp AE, Link TM, Majumdar S. In vivo determination of bone structure in postmenopausal women: a comparison of HR-pQCT and high-field MR imaging. J Bone Miner Res. 2008 Apr; 23(4):463-74.
Krug R, Carballido-Gamio J, Banerjee S, Burghardt AJ, Link TM, Majumdar S. In vivo ultra-high-field magnetic resonance imaging of trabecular bone microarchitecture at 7 T. J Magn Reson Imaging. 2008 Apr; 27(4):854-9.
Keshari KR, Lotz JC, Link TM, Hu S, Majumdar S, Kurhanewicz J. Lactic acid and proteoglycans as metabolic markers for discogenic back pain. Spine (Phila Pa 1976). 2008 Feb 01; 33(3):312-7.
Krug R, Carballido-Gamio J, Banerjee S, Stahl R, Carvajal L, Xu D, Vigneron D, Kelley DA, Link TM, Majumdar S. In vivo bone and cartilage MRI using fully-balanced steady-state free-precession at 7 tesla. Magn Reson Med. 2007 Dec; 58(6):1294-8.
Carballido-Gamio J, Bauer JS, Stahl R, Lee KY, Krause S, Link TM, Majumdar S. Inter-subject comparison of MRI knee cartilage thickness. Med Image Anal. 2008 Apr; 12(2):120-35.
Patel PV, Eckstein F, Carballido-Gamio J, Phan C, Matsuura M, Lochmüller EM, Majumdar S, Link TM. Fuzzy logic structure analysis of trabecular bone of the calcaneus to estimate proximal femur fracture load and discriminate subjects with and without vertebral fractures using high-resolution magnetic resonance imaging at 1.5 T and 3 T. Calcif Tissue Int. 2007 Oct; 81(4):294-304.
Link TM, de Mayo R, O'Donnell RJ. Radiofrequency ablation-an alternative for definitive treatment of solitary bone metastases. Eur Radiol. 2007 Nov; 17(11):3012-3.
Bauer JS, Banerjee S, Henning TD, Krug R, Majumdar S, Link TM. Fast high-spatial-resolution MRI of the ankle with parallel imaging using GRAPPA at 3 T. AJR Am J Roentgenol. 2007 Jul; 189(1):240-5.
Bauer JS, Link TM, Burghardt A, Henning TD, Mueller D, Majumdar S, Prevrhal S. Analysis of trabecular bone structure with multidetector spiral computed tomography in a simulated soft-tissue environment. Calcif Tissue Int. 2007 Jun; 80(6):366-73.
Link TM, Stahl R, Woertler K. Cartilage imaging: motivation, techniques, current and future significance. Eur Radiol. 2007 May; 17(5):1135-46.
Bauer JS, Krause SJ, Ross CJ, Krug R, Carballido-Gamio J, Ozhinsky E, Majumdar S, Link TM. Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracy. Radiology. 2006 Nov; 241(2):399-406.
Barr C, Bauer JS, Malfair D, Ma B, Henning TD, Steinbach L, Link TM. MR imaging of the ankle at 3 Tesla and 1.5 Tesla: protocol optimization and application to cartilage, ligament and tendon pathology in cadaver specimens. Eur Radiol. 2007 Jun; 17(6):1518-28.
Daldrup-Link HE, Henning T, Link TM. MR imaging of therapy-induced changes of bone marrow. Eur Radiol. 2007 Mar; 17(3):743-61.
Blumenkrantz G, Li X, Han ET, Newitt DC, Crane JC, Link TM, Majumdar S. A feasibility study of in vivo T1rho imaging of the intervertebral disc. Magn Reson Imaging. 2006 Oct; 24(8):1001-7.
Lozano J, Li X, Link TM, Safran M, Majumdar S, Ma CB. Detection of posttraumatic cartilage injury using quantitative T1rho magnetic resonance imaging. A report of two cases with arthroscopic findings. J Bone Joint Surg Am. 2006 Jun; 88(6):1349-52.
Carballido-Gamio J, Phan C, Link TM, Majumdar S. Characterization of trabecular bone structure from high-resolution magnetic resonance images using fuzzy logic. Magn Reson Imaging. 2006 Oct; 24(8):1023-9.
Phan CM, Matsuura M, Bauer JS, Dunn TC, Newitt D, Lochmueller EM, Eckstein F, Majumdar S, Link TM. Trabecular bone structure of the calcaneus: comparison of MR imaging at 3.0 and 1.5 T with micro-CT as the standard of reference. Radiology. 2006 May; 239(2):488-96.
Phan CM, Link TM, Blumenkrantz G, Dunn TC, Ries MD, Steinbach LS, Majumdar S. MR imaging findings in the follow-up of patients with different stages of knee osteoarthritis and the correlation with clinical symptoms. Eur Radiol. 2006 Mar; 16(3):608-18.
Li X, Han ET, Ma CB, Link TM, Newitt DC, Majumdar S. In vivo 3T spiral imaging based multi-slice T(1rho) mapping of knee cartilage in osteoarthritis. Magn Reson Med. 2005 Oct; 54(4):929-36.
Lee KY, Masi JN, Sell CA, Schier R, Link TM, Steinbach LS, Safran M, Ma B, Majumdar S. Computer-aided quantification of focal cartilage lesions using MRI: accuracy and initial arthroscopic comparison. Osteoarthritis Cartilage. 2005 Aug; 13(8):728-37.
Link TM, Mischung J, Wörtler K, Burkart A, Rummeny EJ, Imhoff AB. Normal and pathological MR findings in osteochondral autografts with longitudinal follow-up. Eur Radiol. 2006 Jan; 16(1):88-96.
Masi JN, Sell CA, Phan C, Han E, Newitt D, Steinbach L, Majumdar S, Link TM. Cartilage MR imaging at 3.0 versus that at 1.5 T: preliminary results in a porcine model. Radiology. 2005 Jul; 236(1):140-50.
Masi JN, Newitt D, Sell CA, Daldrup-Link H, Steinbach L, Majumdar S, Link TM. Optimization of gadodiamide concentration for MR arthrography at 3 T. AJR Am J Roentgenol. 2005 Jun; 184(6):1754-61.
Link TM, Guglielmi G, van Kuijk C, Adams JE. Radiologic assessment of osteoporotic vertebral fractures: diagnostic and prognostic implications. Eur Radiol. 2005 Aug; 15(8):1521-32.
Blumenkrantz G, Lindsey CT, Dunn TC, Jin H, Ries MD, Link TM, Steinbach LS, Majumdar S. A pilot, two-year longitudinal study of the interrelationship between trabecular bone and articular cartilage in the osteoarthritic knee. Osteoarthritis Cartilage. 2004 Dec; 12(12):997-1005.
Beer A, Saar B, Zantl N, Link TM, Roggel R, Hwang SL, Schwaibold H, Rummeny EJ. MR cystography for bladder tumor detection. Eur Radiol. 2004 Dec; 14(12):2311-9.
Link TM, Majumdar S. Current diagnostic techniques in the evaluation of bone architecture. Curr Osteoporos Rep. 2004 Jun; 2(2):47-52.
Brügel M, Link TM, Rummeny EJ, Lange P, Theisen J, Dobritz M. Assessment of vascular invasion in pancreatic head cancer with multislice spiral CT: value of multiplanar reconstructions. Eur Radiol. 2004 Jul; 14(7):1188-95.
Link TM, Steinbach LS, Ghosh S, Ries M, Lu Y, Lane N, Majumdar S. Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findings. Radiology. 2003 Feb; 226(2):373-81.
Issever AS, Vieth V, Lotter A, Meier N, Laib A, Newitt D, Majumdar S, Link TM. Local differences in the trabecular bone structure of the proximal femur depicted with high-spatial-resolution MR imaging and multisection CT. Acad Radiol. 2002 Dec; 9(12):1395-406.
Link TM, Vieth V, Stehling C, Lotter A, Beer A, Newitt D, Majumdar S. High-resolution MRI vs multislice spiral CT: which technique depicts the trabecular bone structure best? Eur Radiol. 2003 Apr; 13(4):663-71.
Daldrup-Link HE, Rummeny EJ, Ihssen B, Kienast J, Link TM. Iron-oxide-enhanced MR imaging of bone marrow in patients with non-Hodgkin's lymphoma: differentiation between tumor infiltration and hypercellular bone marrow. Eur Radiol. 2002 Jun; 12(6):1557-66.
Beuf O, Ghosh S, Newitt DC, Link TM, Steinbach L, Ries M, Lane N, Majumdar S. Magnetic resonance imaging of normal and osteoarthritic trabecular bone structure in the human knee. Arthritis Rheum. 2002 Feb; 46(2):385-93.
Link TM, Vieth V, Matheis J, Newitt D, Lu Y, Rummeny EJ, Majumdar S. Bone structure of the distal radius and the calcaneus vs BMD of the spine and proximal femur in the prediction of osteoporotic spine fractures. Eur Radiol. 2002 Feb; 12(2):401-8.