Thomas Link, MD, PhD

Professor, & Division Chief, Musculoskeletal Radiology
Clinical Director of MQIR
Director, T32 Program
Professor in Residence

Biography

Thomas M. Link, MD, PhD, is Chief of the Musculoskeletal Imaging Section and Clinical Director of the Musculoskeletal and Quantitative Imaging Research (MQIR) Group in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Dr. Link completed his medical residency in Muenster, Germany. He performed a research fellowship at the University of California, San Francisco in 1996 and was a Visiting Associate Professor at UCSF from 1999-2001. Before joining the Department of Radiology and Biomedical Imaging in 2003 he was a Vice-Chair of the Department of Radiology at the Technical University of Munich.

As Clinical Director of the Musculoskeletal and Quantitative Imaging Research (MQIR) Group, Dr. Link’s main interest is translational research. He wants to provide clinical background to basic science researchers, assessing clinical feasibility of research projects and to apply new imaging techniques in clinical studies.

Dr. Link's research program in MQIR has three main focuses: imaging of osteoporosis, particularly developing new imaging techniques for assessment of bone quality and density, application on new imaging techniques for the clinical assessment of osteoarthritis, cartilage and prevention of cartilage degeneration, and interventional techniques for diagnosis and treatment of bone tumors. Dr. Link has published extensively with more than 400 peer-reviewed articles, 48 review articles, 47 book chapters and 3 books.Dr. Link has published extensively with more than 400 peer-reviewed articles, 48 review articles, 47 book chapters, and 3 books.

Expertise:
Musculoskeletal Radiology

Specialty:
Bone tumors and interventional procedures, osteoporosis and osteoarthritis

Professional Interests:
New techniques for musculoskeletal imaging, osteoporosis, osteoarthritis, cartilage imaging, high field musculoskeletal MRI at 3.0 and 7.0T, MR-guided focused ultrasound

Education and Training:
• Medical School: Johannes-Gutenberg University, Mainz, Germany
• Medical School: Groote Schuur Hospital University of Cape Town, Cape Town, RSA
• Internship: City Hospital Idar-Oberstein, Teaching Hospital of the Johannes-Gutenberg, Mainz Germany
• Residency: Department of Radiology Center for Rheumatic Diseases of the State of Rheinland-Pfalz, Bad Kreuznach, Germany
• Residency: Department of Radiology, KKH Hellersen, Teaching Hospital of the University of Bonn, Germany
• Residency: Department of Radiology, University Hospital, Muenster
• Fellowship: University of California, San Francisco Department of Radiology
• Doctor of Philosophy: University Hospital, Muenster Department of Radiology
• Board Examination in Radiology (including Radiation Therapy), Muenster, Germany
• Board Examination in Diagnostic Radiology, Muenster, Germany
• ECFMG (USMLE, Step 1 and 2)
• Temporary California License
• USMLE Step 3
• DEA License
• Permanent California License
• Fluoroscopy Supervisor License
• Equivalence certification of Doctor of Philosophy (Ph.D.) degree in Medicine (for German qualifications) by Center for Educational Documentation, Boston
• Diagnostic Radiology Core Exam, American Board of Radiology
• Board Certification Diagnostic Radiology, American Board of Radiology

Education

2019 - Diversity, Equity, and Inclusion Champion Training, University of California
1996 - fellowship, University of California
1995 - radiology residency, University of Muenster
M.D., 1987 - medical school, Johannes Gutenberg University

Honors and Awards

Election and Induction to AIMBE College of Fellows, AIMBE (American Institute for Medical and Biological Engineering), 2019
Outstanding Faculty Mentoring Award, Department of Radiology and Biomedical Imaging, UCSF, 2019
16th Annual Lodwick Award, Massachusetts General Hospital/Harvard University, 2019
2017-2018 Long-Term Mentor Award, Pathways to Discovery Board of Directors, UCSF, 2018
Senior Fellow Award, International Society for Magnetic Resonance in Medicine, 2017
Outstanding Reviewer Award, Osteoarthritis&Cartilage, 2017
Distinguished Investigator Award, Academy of Radiology Research, 2016
Certificate of Special Distinction, Skeletal Radiology, 2014
Editor-in-Chief, Current Radiology Reports, 2012
George J. Davies - James A. Gould, Excellence in Clinical Inquiry Award, The Journal of Othopaedic and Sports Physical Therapy, 2012
Editor’s Recognition Award with Distinction, Radiology, 2011
The Founder's Lecturer, International Skeletal Society, Washington, 2009
Editors Recognition, European Journal of Radiology, 2007-2008
Plenary Lecturer, World Congress on Osteoarthritis, Prague. Czech Republic, 2007
Top Cited Award, Osteoarthritis and Cartilage, 2006-2008
Appointed Chairman, Osteoporosis Group of the European Society of Skeletal Radiology (ESSR), 2006
Teaching Award, Medical School of the Technical University of Munich, Germany, 2000
Caffey Award, Society of Pediatric Radiology, 1997

Publications

Shao MM, White TG, Bassett JB, Dowlati E, Mehta SH, Werner C, Golub D, Shah KA, Dehdashti AR, Teron I, Link T, Patsalides A, Woo HH. Intrasaccular Treatment of Intracranial Aneurysms: A Comprehensive Review. J Clin Med. 2024 Oct 16; 13(20).
Luitjens J, Ziegeler K, Yoon D, Gassert F, Bhattacharjee R, Manatrakul R, Ngarmsrikam C, Becker A, Yang Y, Joseph GB, Su P, Itriago-Leon P, Majumdar S, Link TM. Improved metal suppression using new generation low-field MRI: a biophantom feasibility study. Skeletal Radiol. 2024 Oct 04.
Serfaty A, Link TM. Introduction to the special issue on imaging of infection. Skeletal Radiol. 2024 Oct; 53(10):1955-1956.
Spaanderman DJ, Hakkesteegt SN, Hanff DF, Schut ARW, Schiphouwer LM, Vos M, Messiou C, Doran SJ, Jones RL, Hayes AJ, Nardo L, Abdelhafez YG, Moawad AW, Elsayes KM, Lee S, Link TM, Niessen WJ, van Leenders GJLH, Visser JJ, Klein S, Grünhagen DJ, Verhoef C, Starmans MPA. Multi-center external validation of an automated method segmenting and differentiating atypical lipomatous tumors from lipomas using radiomics and deep-learning on MRI. EClinicalMedicine. 2024 Oct; 76:102802.
Sinha Gregory N, Burghardt AJ, Backlund JC, Rubin MR, Bebu I, Braffett BH, Kenny DJ, Link TM, Kazakia GJ, Barnie A, Lachin JM, Gubitosi-Klug R, de Boer IH, Schwartz AV, DCCT/EDIC Research Group. Diabetes Risk Factors and Bone Microarchitecture as Assessed by High-Resolution Peripheral Quantitative Computed Tomography in Adults With Long-standing Type 1 Diabetes. Diabetes Care. 2024 Sep 01; 47(9):1548-1558.
Link TM, Palmer WE, Guermazi A. Introduction to the International Skeletal Society 50-Year Anniversary Special Issue-50 years of labor, adaptation, and success. Skeletal Radiol. 2024 Sep; 53(9):1665-1666.
Akkaya Z, Giesler PJ, Roach KE, Joseph GB, McCulloch CE, Bharadwaj UU, Souza RB, Majumdar S, Link TM. Ligamentum teres lesions are associated with compositional and structural hip cartilage degenerative change: region-specific cartilage degeneration. Eur Radiol. 2024 Aug 23.
Flores SE, Manatrakul R, Anigwe C, Ngarmsrikam C, Feeley BT, Ma CB, Link TM, Lansdown DA. Prognostic Factors on Preoperative MRI for Patient-Reported Outcomes After Posterior Medial Meniscus Root Repair. Orthop J Sports Med. 2024 Aug; 12(8):23259671241263648.
Distefano G, Harrison S, Lynch J, Link TM, Kramer PA, Ramos SV, Mau T, Coen PM, Sparks LM, Goodpaster BH, Cawthon PM, Cauley JA, Lane NE. Skeletal Muscle Composition, Power, and Mitochondrial Energetics in Older Men and Women With Knee Osteoarthritis. Arthritis Rheumatol. 2024 Jul 17.
Griebler R, Schütze D, Link T, Schindler K. Brief instruments for measuring nutrition literacy - the Nutrition Health Literacy Scale and the Self-Perceived Food Literacy Scale Short Form. Nutr J. 2024 Jul 11; 23(1):73.
Li X, Kim J, Yang M, Ok AH, Zbýn Š, Link TM, Majumdar S, Ma CB, Spindler KP, Winalski CS. Cartilage compositional MRI-a narrative review of technical development and clinical applications over the past three decades. Skeletal Radiol. 2024 Sep; 53(9):1761-1781.
Gassert FG, Joseph GB, Lynch JA, Luitjens J, Nevitt MC, McCulloch CE, Lane NE, Majumdar S, Link TM. Clinical and imaging findings associated with preservation of knee joint health over 8 years in individuals aged 65 and over: data from the OAI. BMC Musculoskelet Disord. 2024 Jun 26; 25(1):495.
Guimaraes JB, Manatrakul R, Joseph GB, Feeley B, Lansdown DA, Chen JV, Baal JD, Link TM. Degenerative medial and lateral menisci root tears: demographics, clinical presentation, imaging features, and associated findings. Skeletal Radiol. 2024 Jun 25.
Moradi K, Mohajer B, Mohammadi S, Guermazi A, Ibad HA, Roemer FW, Cao X, Link TM, Demehri S. Thigh muscle composition changes in knee osteoarthritis patients during weight loss: Sex-specific analysis using data from osteoarthritis initiative. Osteoarthritis Cartilage. 2024 Sep; 32(9):1154-1162.
Ashmeik W, Schirò S, Joseph GB, Link TM. Associations of cumulative voriconazole dose, treatment duration, and alkaline phosphatase with voriconazole-induced periostitis. Skeletal Radiol. 2024 May 17.
Filley A, Baldwin A, Ben-Natan AR, Hansen K, Arora A, Xiao A, Hammond D, Chen C, Tweedt I, Rohde J, Link T, Berven S, Sawyer A. The influence of osteoporosis on mechanical complications in lumbar fusion surgery: a systematic review. N Am Spine Soc J. 2024 Jun; 18:100327.
Coburn SL, Crossley KM, Kemp JL, Gassert F, Luitjens J, Warden SJ, Culvenor AG, Scholes MJ, King MG, Lawrenson P, Link TM, Heerey JJ. Association between hip muscle strength/function and hip cartilage defects in sub-elite football players with hip/groin pain. Osteoarthritis Cartilage. 2024 Jul; 32(7):943-951.
Löffler MT, Ngarmsrikam C, Giesler P, Joseph GB, Akkaya Z, Lynch JA, Lane NE, Nevitt M, McCulloch CE, Link TM. Effect of weight loss on knee joint synovitis over 48 months and mediation by subcutaneous fat around the knee: data from the Osteoarthritis Initiative. BMC Musculoskelet Disord. 2024 Apr 17; 25(1):300.
Manatrakul R, Loeffler M, Bharadwaj UU, Joseph GB, Lansdown D, Feeley B, Baal JD, Guimaraes JB, Link TM. Clinical and radiologic outcomes in patients with meniscal root tears. BMC Musculoskelet Disord. 2024 Mar 23; 25(1):232.
Heerey JJ, Souza RB, Link TM, Luitjens J, Gassert F, Kemp JL, Scholes MJ, Crossley KM. Defining hip osteoarthritis feature prevalence, severity, and change using the Scoring of Hip Osteoarthritis with MRI (SHOMRI). Skeletal Radiol. 2024 Aug; 53(8):1599-1609.
Löffler MT, Wu PH, Pirmoazen AM, Joseph GB, Stewart JM, Saeed I, Liu J, Schafer AL, Schwartz AV, Link TM, Kazakia GJ. Microvascular disease not type 2 diabetes is associated with increased cortical porosity: A study of cortical bone microstructure and intracortical vessel characteristics. Bone Rep. 2024 Mar; 20:101745.
Löffler MT, Akkaya Z, Bhattacharjee R, Link TM. Biomarkers of Cartilage Composition. Semin Musculoskelet Radiol. 2024 Feb; 28(1):26-38.
Kanthawang T, Wudhikulprapan W, Phinyo P, Settakorn J, Pruksakorn D, Link TM, Pattamapaspong N. Can conventional magnetic resonance imaging at presentation predict chemoresistance in osteosarcoma? Br J Radiol. 2024 Feb 02; 97(1154):451-461.
Manatrakul R, Pirmoazen AM, Bharadwaj UU, Akkaya Z, Giesler PJ, Lynch JA, Nevitt MC, McCulloch CE, Joseph GB, Link TM. Thigh muscle and fat volumes are associated with knee cartilage abnormalities and bone marrow edema-like lesions: data from the osteoarthritis initiative. Skeletal Radiol. 2024 Jul; 53(7):1279-1286.
Luitjens J, Gassert FG, Patwardhan V, Bhattacharjee R, Joseph GB, Zhang AL, Souza RB, Majumdar S, Link TM. Is hip capsule morphology associated with hip pain in patients without another structural correlate? Eur Radiol. 2024 Jul; 34(7):4321-4330.
Boone SL, Horvai AE, Zimel MN, Brown R, Link TM, McGill KC. Botryomycosis: a rare mimic of sarcoma as an initial presentation of acquired immunodeficiency syndrome. Skeletal Radiol. 2024 Oct; 53(10):2315-2320.
Wu PH, Joseph G, Saeed I, Pirmoazen AM, Kenny K, Kim TY, Schafer AL, Schwartz AV, Li X, Link TM, Kazakia GJ. Bone Marrow Adiposity Alterations in Type 2 Diabetes Are Sex-Specific and Associated with Serum Lipid Levels. J Bone Miner Res. 2023 12; 38(12):1877-1884.
White TG, Santhumayor BA, Turpin J, Shah K, Toscano D, Teron I, Link T, Patsalides A, Woo HH. Flow diverter surface modifications for aneurysm treatment: A review of the mechanisms and data behind existing technologies. Interv Neuroradiol. 2023 Oct 29; 15910199231207550.
Kazmi M, Zhang WR, Hsiao E, Gross A, Grouse K, Link TM, Tetzlaff M, Theodosopoulos P, Haemel A. Frontal bone loss following coronal brow lift: A mimicker of head variant linear morphea. JAAD Case Rep. 2023 Nov; 41:4-6.
Joseph GB, Takakusagi M, Arcilla G, Lynch JA, Pedoia V, Majumdar S, Lane NE, Nevitt MC, McCulloch CE, Link TM. Associations between weight change, knee subcutaneous fat and cartilage thickness in overweight and obese individuals: 4-Year data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2023 11; 31(11):1515-1523.
Sollmann N, Fields AJ, O'Neill C, Nardo L, Majumdar S, Chin CT, Tosun D, Han M, Vu AT, Ozhinsky E, Shah LM, Harris RE, Lobo R, Anderst W, Herzog R, Psioda MA, Standaert CJ, Price RT, Lotz JC, Link TM, Krug R. Magnetic Resonance Imaging of the Lumbar Spine: Recommendations for Acquisition and Image Evaluation from the BACPAC Spine Imaging Working Group. Pain Med. 2023 08 04; 24(Suppl 1):S81-S94.
Han M, Bahroos E, Hess ME, Chin CT, Gao KT, Shin DD, Villanueva-Meyer JE, Link TM, Pedoia V, Majumdar S. Technology and Tool Development for BACPAC: Qualitative and Quantitative Analysis of Accelerated Lumbar Spine MRI with Deep-Learning Based Image Reconstruction at 3T. Pain Med. 2023 08 04; 24(Suppl 1):S149-S159.
Link TM, Schafer AL. Bariatric Surgery Negatively Impacts Bone Health in Adolescents. Radiology. 2023 06; 307(5):e231260.
McGill KC, Link TM. Introduction to the special issue on image-guided joint interventions. Skeletal Radiol. 2023 05; 52(5):815.
Tolpadi AA, Luitjens J, Gassert FG, Li X, Link TM, Majumdar S, Pedoia V. Synthetic Inflammation Imaging with PatchGAN Deep Learning Networks. Bioengineering (Basel). 2023 Apr 25; 10(5).
da Silva LNM, Guimarães JB, Link TM, da Cruz IAN, Silva FD, Nico MAC, Filho AGO. Prevalence of phalangeal bone marrow edema on MRI before and during the COVID-19 pandemic and correlation with chilblain skin lesions. Skeletal Radiol. 2023 Sep; 52(9):1721-1728.
Link TM, Joseph GB, Li X. MRI-based T1rho and T2 cartilage compositional imaging in osteoarthritis: what have we learned and what is needed to apply it clinically and in a trial setting? Skeletal Radiol. 2023 Nov; 52(11):2137-2147.
Bharadwaj UU, Christine M, Li S, Chou D, Pedoia V, Link TM, Chin CT, Majumdar S. Deep learning for automated, interpretable classification of lumbar spinal stenosis and facet arthropathy from axial MRI. Eur Radiol. 2023 May; 33(5):3435-3443.
Li X, Roemer FW, Cicuttini F, MacKay JW, Turmezei T, Link TM. Early knee OA definition-what do we know at this stage? An imaging perspective. Ther Adv Musculoskelet Dis. 2023; 15:1759720X231158204.
Liu CC, Abdelhafez YG, Yap SP, Acquafredda F, Schirò S, Wong AL, Sarohia D, Bateni C, Darrow MA, Guindani M, Lee S, Zhang M, Moawad AW, Ng QK, Shere L, Elsayes KM, Maroldi R, Link TM, Nardo L, Qi J. AI-Based Automated Lipomatous Tumor Segmentation in MR Images: Ensemble Solution to Heterogeneous Data. J Digit Imaging. 2023 06; 36(3):1049-1059.
Bonnheim NB, Lazar AA, Kumar A, Akkaya Z, Zhou J, Guo X, O'Neill C, Link TM, Lotz JC, Krug R, Fields AJ. ISSLS Prize in Bioengineering Science 2023: Age- and sex-related differences in lumbar intervertebral disc degeneration between patients with chronic low back pain and asymptomatic controls. Eur Spine J. 2023 05; 32(5):1517-1524.
Bharadwaj UU, Akkaya Z, Horvai AE, Link TM, Gassert FG. Calcifying fibrous tumor: a rare case in the foot. Skeletal Radiol. 2023 Aug; 52(8):1619-1623.
Joseph GB, McCulloch CE, Nevitt MC, Lynch J, Lane NE, Pedoia V, Majumdar S, Link TM. The effect of interactions between BMI and sustained depressive symptoms on knee osteoarthritis over 4 years: data from the osteoarthritis initiative. BMC Musculoskelet Disord. 2023 Jan 12; 24(1):27.
Hayashi D, Roemer FW, Link T, Li X, Kogan F, Segal NA, Omoumi P, Guermazi A. Latest advancements in imaging techniques in OA. Ther Adv Musculoskelet Dis. 2022; 14:1759720X221146621.
Baal JD, Cecil KL, Patel R, O'Brien M, McGill K, Link TM. Imaging of Overuse Injuries of the Hip. Radiol Clin North Am. 2023 Mar; 61(2):191-201.
Lee JJ, Namiri NK, Astuto B, Link TM, Majumdar S, Pedoia V. Personalized Risk Model and Leveraging of Magnetic Resonance Imaging-Based Structural Phenotypes and Clinical Factors to Predict Incidence of Radiographic Osteoarthritis. Arthritis Care Res (Hoboken). 2023 03; 75(3):501-508.
Shah R, Astuto Arouche Nunes B, Gleason T, Fletcher W, Banaga J, Sweetwood K, Ye A, Patel R, McGill K, Link T, Crane J, Pedoia V, Majumdar S. Utilizing a Digital Swarm Intelligence Platform to Improve Consensus Among Radiologists and Exploring Its Applications. J Digit Imaging. 2023 04; 36(2):401-413.
Joseph GB, McCulloch CE, Nevitt MC, Lynch J, Lane NE, Link TM. Effects of Weight Change on Knee and Hip Radiographic Measurements and Pain Over Four Years: Data From the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2023 04; 75(4):860-868.
Lartey R, Nanavati A, Kim J, Li M, Xu K, Nakamura K, Shin W, Winalski CS, Obuchowski N, Bahroos E, Link TM, Hardy PA, Peng Q, Kim J, Liu K, Fung M, Wu C, Li X. Reproducibility of T1ρ and T2 quantification in a multi-vendor multi-site study. Osteoarthritis Cartilage. 2023 02; 31(2):249-257.
Xie D, Tanaka M, Pedoia V, Li AK, Facchetti L, Neumann J, Lartey R, Souza RB, Link TM, Benjamin Ma C, Li X. Baseline cartilage T1ρ and T2 predicted patellofemoral joint cartilage lesion progression and patient-reported outcomes after ACL reconstruction. J Orthop Res. 2023 06; 41(6):1310-1319.
Bharadwaj UU, Ben-Natan AR, Huang J, Pedoia V, Chou D, Majumdar S, Link TM, Chin CT. Evaluation of 2 Novel Ratio-Based Metrics for Lumbar Spinal Stenosis. AJNR Am J Neuroradiol. 2022 10; 43(10):1530-1538.
Bazzocchi A, Isaac A, Dalili D, Fotiadou A, Kariki EP, Kirschke JS, Krestan CR, Messina C, Oei EHG, Phan CM, Prakash M, Sabir N, Tagliafico A, Aparisi F, Baum T, Link TM, Guglielmi G, Aparisi Gómez MP. Imaging of Metabolic Bone Diseases: The Spine View, Part I. Semin Musculoskelet Radiol. 2022 Aug; 26(4):478-490.
Aparisi Gómez MP, Isaac A, Dalili D, Fotiadou A, Kariki EP, Kirschke JS, Krestan CR, Messina C, Oei EHG, Phan CM, Prakash M, Sabir N, Tagliafico A, Aparisi F, Baum T, Link TM, Guglielmi G, Bazzocchi A. Imaging of Metabolic Bone Diseases: The Spine View, Part II. Semin Musculoskelet Radiol. 2022 Aug; 26(4):491-500.
Finbråten HS, Nowak P, Griebler R, Bíró É, Vrdelja M, Charafeddine R, Griese L, Bøggild H, Schaeffer D, Link T, Kucera Z, Mancini J, Pelikan JM. The HLS19-COM-P, a New Instrument for Measuring Communicative Health Literacy in Interaction with Physicians: Development and Validation in Nine European Countries. Int J Environ Res Public Health. 2022 09 14; 19(18).
Neumann J, Zhang AL, Bucknor M, Majumdar S, Souza R, Joseph GB, Link TM. Acetabular cartilage delamination: performance of MRI using arthroscopy as the standard of reference. Acta Radiol. 2023 Mar; 64(3):1122-1129.
Liao TC, Pedoia V, Link TM, Majumdar S, Souza RB. Association of patella alignment with cartilage relaxation times and self-reported symptoms in individuals with patellofemoral degeneration. J Orthop Res. 2023 03; 41(3):562-569.
Gao KT, Tibrewala R, Hess M, Bharadwaj UU, Inamdar G, Link TM, Chin CT, Pedoia V, Majumdar S. Automatic detection and voxel-wise mapping of lumbar spine Modic changes with deep learning. JOR Spine. 2022 Jun; 5(2):e1204.
Ramezanpour S, Kanthawang T, Lynch J, McCulloch CE, Nevitt MC, Link TM, Joseph GB. Impact of Sustained Synovitis on Knee Joint Structural Degeneration: 4-Year MRI Data from the Osteoarthritis Initiative. J Magn Reson Imaging. 2023 01; 57(1):153-164.
Sollmann N, Kirschke JS, Kronthaler S, Boehm C, Dieckmeyer M, Vogele D, Kloth C, Lisson CG, Carballido-Gamio J, Link TM, Karampinos DC, Karupppasamy S, Beer M, Krug R, Baum T. Imaging of the Osteoporotic Spine - Quantitative Approaches in Diagnostics and for the Prediction of the Individual Fracture Risk. Rofo. 2022 10; 194(10):1088-1099.
Carballido-Gamio J, Posadzy M, Wu PH, Kenny K, Saeed I, Link TM, Tien PC, Krug R, Kazakia GJ. People living with HIV have low trabecular bone mineral density, high bone marrow adiposity, and poor trabecular bone microarchitecture at the proximal femur. Osteoporos Int. 2022 Aug; 33(8):1739-1753.
Bonnheim NB, Wang L, Lazar AA, Zhou J, Chachad R, Sollmann N, Guo X, Iriondo C, O'Neill C, Lotz JC, Link TM, Krug R, Fields AJ. The contributions of cartilage endplate composition and vertebral bone marrow fat to intervertebral disc degeneration in patients with chronic low back pain. Eur Spine J. 2022 07; 31(7):1866-1872.
Scholes MJ, Kemp JL, Mentiplay BF, Heerey JJ, Agricola R, Semciw AI, Souza RB, Link TM, Majumdar S, King MG, Lawrenson PR, Crossley KM. Does Femoroacetabular Impingement Syndrome Affect Self-Reported Burden in Football Players With Hip and Groin Pain? Sports Health. 2022 Nov-Dec; 14(6):920-931.
Guimarães JB, Chemin RN, Araujo FF, Link TM, Silva FD, Bitar A, Nico MAC, Filho AGO. Meniscal Root Tears: An Update Focused on Preoperative and Postoperative MRI Findings. AJR Am J Roentgenol. 2022 08; 219(2):269-278.
Sollmann N, Bonnheim NB, Joseph GB, Chachad R, Zhou J, Akkaya Z, Pirmoazen AM, Bailey JF, Guo X, Lazar AA, Link TM, Fields AJ, Krug R. Paraspinal Muscle in Chronic Low Back Pain: Comparison Between Standard Parameters and Chemical Shift Encoding-Based Water-Fat MRI. J Magn Reson Imaging. 2022 11; 56(5):1600-1608.
Chang CY, Link TM. Introduction to the special issue on artificial intelligence in musculoskeletal radiology. Skeletal Radiol. 2022 Feb; 51(2):233.
Bharadwaj UU, Coy A, Motamedi D, Sun D, Joseph GB, Krug R, Link TM. CT-like MRI: a qualitative assessment of ZTE sequences for knee osseous abnormalities. Skeletal Radiol. 2022 Aug; 51(8):1585-1594.
Heilmeier U, Hackl M, Schroeder F, Torabi S, Kapoor P, Vierlinger K, Eiriksdottir G, Gudmundsson EF, Harris TB, Gudnason V, Link TM, Grillari J, Schwartz AV. Circulating serum microRNAs including senescent miR-31-5p are associated with incident fragility fractures in older postmenopausal women with type 2 diabetes mellitus. Bone. 2022 05; 158:116308.
Sollmann N, Becherucci EA, Boehm C, Husseini ME, Ruschke S, Burian E, Kirschke JS, Link TM, Subburaj K, Karampinos DC, Krug R, Baum T, Dieckmeyer M. Texture Analysis Using CT and Chemical Shift Encoding-Based Water-Fat MRI Can Improve Differentiation Between Patients With and Without Osteoporotic Vertebral Fractures. Front Endocrinol (Lausanne). 2021; 12:778537.
Bucknor MD, Baal JD, McGill KC, Infosino A, Link TM. Musculoskeletal Applications of Magnetic Resonance-Guided Focused Ultrasound. Semin Musculoskelet Radiol. 2021 Dec; 25(6):725-734.
Link TM, Pedoia V. Using AI to Improve Radiographic Fracture Detection. Radiology. 2022 03; 302(3):637-638.
Heerey J, Kemp J, Agricola R, Srinivasan R, Smith A, Pizzari T, King M, Lawrenson P, Scholes M, Link T, Souza R, Majumdar S, Crossley K. Cam morphology is associated with MRI-defined cartilage defects and labral tears: a case-control study of 237 young adult football players with and without hip and groin pain. BMJ Open Sport Exerc Med. 2021; 7(4):e001199.
Bolcos PO, Mononen ME, Roach KE, Tanaka MS, Suomalainen JS, Mikkonen S, Nissi MJ, Töyräs J, Link TM, Souza RB, Majumdar S, Ma CB, Li X, Korhonen RK. Subject-specific biomechanical analysis to estimate locations susceptible to osteoarthritis-Finite element modeling and MRI follow-up of ACL reconstructed patients. J Orthop Res. 2022 08; 40(8):1744-1755.
Joseph GB, McCulloch CE, Nevitt MC, Link TM, Sohn JH. Machine learning to predict incident radiographic knee osteoarthritis over 8 Years using combined MR imaging features, demographics, and clinical factors: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2022 02; 30(2):270-279.
Joseph GB, McCulloch CE, Sohn JH, Pedoia V, Majumdar S, Link TM. AI MSK clinical applications: cartilage and osteoarthritis. Skeletal Radiol. 2022 Feb; 51(2):331-343.
Chang CY, Guimares JB, Joseph G, de Toledo Petrilli M, Lozano-Calderon S, Bredella MA, Link TM. Percutaneous CT-guided corticosteroid injection for the treatment of osseous Langerhans cell histocytosis: a three institution retrospective analysis. Skeletal Radiol. 2022 May; 51(5):1037-1046.
Orozco GA, Eskelinen ASA, Kosonen JP, Tanaka MS, Yang M, Link TM, Ma B, Li X, Grodzinsky AJ, Korhonen RK, Tanska P. Shear strain and inflammation-induced fixed charge density loss in the knee joint cartilage following ACL injury and reconstruction: A computational study. J Orthop Res. 2022 07; 40(7):1505-1522.
Chalian M, Li X, Guermazi A, Obuchowski NA, Carrino JA, Oei EH, Link TM, RSNA QIBA MSK Biomarker Committee, SNA QIBA MSK Biomarker Committee Members. The QIBA Profile for MRI-based Compositional Imaging of Knee Cartilage. Radiology. 2021 11; 301(2):423-432.
Ryu B, White TG, Shah KA, Turpin J, Link T, Dehdashti AR, Katz JM, Black K, Woo HH. Utility of quantitative magnetic resonance angiography and non-invasive optimal vessel analysis for identification of complications and long-term hemodynamic changes in post-pipeline embolization patients. Interv Neuroradiol. 2022 Aug; 28(4):396-403.
Kumar D, Link TM, Jafarzadeh SR, LaValley MP, Majumdar S, Souza RB. Association of Quadriceps Adiposity With an Increase in Knee Cartilage, Meniscus, or Bone Marrow Lesions Over Three Years. Arthritis Care Res (Hoboken). 2021 08; 73(8):1134-1139.
Nguyen KH, Shaw C, Link TM, Majumdar S, Souza RB, Vail TP, Zhang AL. Changes in Hip Capsule Morphology after Arthroscopic Treatment for Femoroacetabular Impingement Syndrome with Periportal Capsulotomy are Correlated With Improvements in Patient-Reported Outcomes. Arthroscopy. 2022 02; 38(2):394-403.
Bodden J, Joseph GB, Schirò S, Lynch JA, Lane NE, McCulloch CE, Nevitt MC, Link TM. Opioid users show worse baseline knee osteoarthritis and faster progression of degenerative changes: a retrospective case-control study based on data from the Osteoarthritis Initiative (OAI). Arthritis Res Ther. 2021 05 22; 23(1):146.
Baal JD, Chen WC, Baal U, Wagle S, Baal JH, Link TM, Bucknor MD. Efficacy and safety of magnetic resonance-guided focused ultrasound for the treatment of painful bone metastases: a systematic review and meta-analysis. Skeletal Radiol. 2021 Dec; 50(12):2459-2469.
Astuto B, Flament I, Namiri NK, Shah R, Bharadwaj U, Link TM, Bucknor MD, Pedoia V, Majumdar S. Erratum: Automatic Deep Learning-assisted Detection and Grading of Abnormalities in Knee MRI Studies. Radiol Artif Intell. 2021 May; 3(3):e219001.
Kanthawang T, Bodden J, Joseph GB, Vail T, Ward D, Patel R, Link TM. Diagnostic value of fluoroscopy-guided hip aspiration for periprosthetic joint infection. Skeletal Radiol. 2021 Nov; 50(11):2245-2254.
Aivazoglou LU, Guimarães JB, Link TM, Costa MAF, Cardoso FN, de Mattos Lombardi Badia B, Farias IB, de Rezende Pinto WBV, de Souza PVS, Oliveira ASB, de Siqueira Carvalho AA, Aihara AY, da Rocha Corrêa Fernandes A. MR imaging of inherited myopathies: a review and proposal of imaging algorithms. Eur Radiol. 2021 Nov; 31(11):8498-8512.
Joseph GB, Ramezanpour S, McCulloch CE, Nevitt MC, Lynch J, Lane NE, Pedoia V, Majumdar S, Link TM. Weight Cycling and Knee Joint Degeneration in Individuals with Overweight or Obesity: Four-Year Magnetic Resonance Imaging Data from the Osteoarthritis Initiative. Obesity (Silver Spring). 2021 05; 29(5):909-918.
Gersing AS, Schwaiger BJ, Nevitt MC, Joseph GB, Feuerriegel G, Jungmann PM, Guimaraes JB, Facchetti L, McCulloch CE, Makowski MR, Link TM. Anterior cruciate ligament abnormalities are associated with accelerated progression of knee joint degeneration in knees with and without structural knee joint abnormalities: 96-month data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2021 07; 29(7):995-1005.
Heilmeier U, Joseph GB, Pasco C, Dinh N, Torabi S, Darakananda K, Youm J, Carballido-Gamio J, Burghardt AJ, Link TM, Kazakia GJ. Longitudinal Evolution of Bone Microarchitecture and Bone Strength in Type 2 Diabetic Postmenopausal Women With and Without History of Fragility Fractures-A 5-Year Follow-Up Study Using High Resolution Peripheral Quantitative Computed Tomography. Front Endocrinol (Lausanne). 2021; 12:599316.
Huang LW, Sun D, Link TM, Lang T, Ai W, Kaplan LD, Steinman MA, Andreadis C. High incidence of fractures after R-CHOP-like chemotherapy for aggressive B-cell non-Hodgkin lymphomas. Support Care Cancer. 2021 Sep; 29(9):5399-5408.
Bodden J, Ok AH, Joseph GB, Nevitt MC, McCulloch CE, Lane NE, Link TM. Joint-adjacent Adipose Tissue by MRI is Associated With Prevalence and Progression of Knee Degenerative Changes: Data from the Osteoarthritis Initiative. J Magn Reson Imaging. 2021 07; 54(1):155-165.
Ramezanpour S, Horvai AE, Piawah S, Link TM. Primary osteosarcoma of the parietal bone. Skeletal Radiol. 2021 Aug; 50(8):1729-1733.
Zorzenoni FO, Link TM, de Biase Cabral de Sousa B, de Menezes Y, Guimarães JB. Histoplasmosis tenosynovitis of the forearm and wrist: imaging, surgical and pathologic findings. Skeletal Radiol. 2021 Aug; 50(8):1723-1728.
Garita B, Maligro J, Sadoughi S, Wu PH, Liebenberg E, Horvai A, Link TM, Kazakia GJ. Microstructural abnormalities are evident by histology but not HR-pQCT at the periosteal cortex of the human tibia under CVD and T2D conditions. Med Nov Technol Devices. 2021 Jun; 10.
Tibrewala R, Pedoia V, Lee J, Kinnunen C, Popovic T, Zhang AL, Link TM, Souza RB, Majumdar S. Automatic hip abductor muscle fat fraction estimation and association with early OA cartilage degeneration biomarkers. J Orthop Res. 2021 11; 39(11):2376-2387.
Shah KA, White TG, Teron I, Link T, Dehdashti AR, Katz JM, Woo HH. Volume-based sizing of the Woven EndoBridge (WEB) device: A preliminary assessment of a novel method for device size selection. Interv Neuroradiol. 2021 Aug; 27(4):473-480.
Schirò S, Foreman SC, Joseph GB, Souza RB, McCulloch CE, Nevitt MC, Link TM. Impact of different physical activity types on knee joint structural degeneration assessed with 3-T MRI in overweight and obese subjects: data from the osteoarthritis initiative. Skeletal Radiol. 2021 Jul; 50(7):1427-1440.
Heerey JJ, Srinivasan R, Agricola R, Smith A, Kemp JL, Pizzari T, King MG, Lawrenson PR, Scholes MJ, Souza RB, Link T, Majumdar S, Crossley KM. Prevalence of early hip OA features on MRI in high-impact athletes. The femoroacetabular impingement and hip osteoarthritis cohort (FORCe) study. Osteoarthritis Cartilage. 2021 03; 29(3):323-334.
Roach KE, Pedoia V, Lee JJ, Popovic T, Link TM, Majumdar S, Souza RB. Multivariate functional principal component analysis identifies waveform features of gait biomechanics related to early-to-moderate hip osteoarthritis. J Orthop Res. 2021 08; 39(8):1722-1731.
Kanthawang T, Lee A, Baal JD, Joseph GB, Vail T, Link TM, Patel R. Predicting outcomes in patients undergoing intra-articular corticosteroid hip injections. Skeletal Radiol. 2021 Jul; 50(7):1347-1357.
Pishgar F, Guermazi A, Roemer FW, Link TM, Demehri S. Conventional MRI-based subchondral trabecular biomarkers as predictors of knee osteoarthritis progression: data from the Osteoarthritis Initiative. Eur Radiol. 2021 Jun; 31(6):3564-3573.
Patel R, Link TM. Abbreviated Musculoskeletal MRI Protocols: Counterpoint-Worsened Patient Care and Radiologist Burnout. AJR Am J Roentgenol. 2021 01; 216(1):35-36.
Liao TC, Jergas H, Tibrewala R, Bahroos E, Link TM, Majumdar S, Souza RB, Pedoia V. Longitudinal analysis of the contribution of 3D patella and trochlear bone shape on patellofemoral joint osteoarthritic features. J Orthop Res. 2021 03; 39(3):506-515.
Ramezanpour S, Horvai AE, Zimel M, Bucknor M, Link TM. Fibroma-like perivascular epithelioid cell tumor: a rare case in a long bone. Skeletal Radiol. 2021 Apr; 50(4):821-825.
Guimaraes JB, Schwaiger BJ, Gersing AS, Neumann J, Facchetti L, Li X, Joseph GB, Link TM. Meniscal ramp lesions: frequency, natural history, and the effect on knee cartilage over 2 years in subjects with anterior cruciate ligament tears. Skeletal Radiol. 2021 Mar; 50(3):551-558.
Zhou J, Damasceno PF, Chachad R, Cheung JR, Ballatori A, Lotz JC, Lazar AA, Link TM, Fields AJ, Krug R. Automatic Vertebral Body Segmentation Based on Deep Learning of Dixon Images for Bone Marrow Fat Fraction Quantification. Front Endocrinol (Lausanne). 2020; 11:612.
Joseph GB, McCulloch CE, Nevitt MC, Neumann J, Lynch JA, Lane NE, Link TM. Associations Between Vitamins C and D Intake and Cartilage Composition and Knee Joint Morphology Over 4 Years: Data From the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2020 09; 72(9):1239-1247.
Bodden J, Sun D, Joseph GB, Huang LW, Andreadis C, Hughes-Fulford M, Lang TF, Link TM. Identification of non-Hodgkin lymphoma patients at risk for treatment-related vertebral density loss and fractures. Osteoporos Int. 2021 Feb; 32(2):281-291.
Ashmeik W, Baal JD, Foreman SC, Joseph GB, Bahroos E, Han M, Krug R, Link TM. Investigating the Association of Metabolic Biomarkers With Knee Cartilage Composition and Structural Abnormalities Using MRI: A Pilot Study. Cartilage. 2021 12; 13(1_suppl):630S-638S.
Kim J, Mamoto K, Lartey R, Xu K, Nakamura K, Shin W, Winalski CS, Obuchowski N, Tanaka M, Bahroos E, Link TM, Hardy PA, Peng Q, Reddy R, Botto-van Bemden A, Liu K, Peters RD, Wu C, Li X. Multi-vendor multi-site T1ρ and T2 quantification of knee cartilage. Osteoarthritis Cartilage. 2020 12; 28(12):1539-1550.
Namiri NK, Flament I, Astuto B, Shah R, Tibrewala R, Caliva F, Link TM, Pedoia V, Majumdar S. Deep Learning for Hierarchical Severity Staging of Anterior Cruciate Ligament Injuries from MRI. Radiol Artif Intell. 2020 Jul 29; 2(4):e190207.
Liu Y, Joseph GB, Foreman SC, Li X, Lane NE, Nevitt MC, McCulloch CE, Link TM. Determining a Threshold of Medial Meniscal Extrusion for Prediction of Knee Pain and Cartilage Damage Progression Over 4 Years: Data From the Osteoarthritis Initiative. AJR Am J Roentgenol. 2021 05; 216(5):1318-1328.
Razmjoo A, Caliva F, Lee J, Liu F, Joseph GB, Link TM, Majumdar S, Pedoia V. T2 analysis of the entire osteoarthritis initiative dataset. J Orthop Res. 2021 01; 39(1):74-85.
Kanthawang T, Bodden J, Joseph GB, Lane NE, Nevitt M, McCulloch CE, Link TM. Obese and overweight individuals have greater knee synovial inflammation and associated structural and cartilage compositional degeneration: data from the osteoarthritis initiative. Skeletal Radiol. 2021 Jan; 50(1):217-229.
Orozco GA, Bolcos P, Mohammadi A, Tanaka MS, Yang M, Link TM, Ma B, Li X, Tanska P, Korhonen RK. Prediction of local fixed charge density loss in cartilage following ACL injury and reconstruction: A computational proof-of-concept study with MRI follow-up. J Orthop Res. 2021 05; 39(5):1064-1081.
Shaw C, Warwick H, Nguyen KH, Link TM, Majumdar S, Souza RB, Vail TP, Zhang AL. Correlation of hip capsule morphology with patient symptoms from femoroacetabular impingement. J Orthop Res. 2021 03; 39(3):590-596.
Liao TC, Martinez AGM, Pedoia V, Ma BC, Li X, Link TM, Majumdar S, Souza RB. Patellar Malalignment Is Associated With Patellofemoral Lesions and Cartilage Relaxation Times After Hamstring Autograft Anterior Cruciate Ligament Reconstruction. Am J Sports Med. 2020 07; 48(9):2242-2251.
Posadzy M, Joseph GB, McCulloch CE, Nevitt MC, Lynch JA, Lane NE, Link TM. Natural history of new horizontal meniscal tears in individuals at risk for and with mild to moderate osteoarthritis: data from osteoarthritis initiative. Eur Radiol. 2020 Nov; 30(11):5971-5980.
Foreman SC, Liu Y, Nevitt MC, Neumann J, Joseph GB, Lane NE, McCulloch CE, Link TM. Meniscal Root Tears and Extrusion Are Significantly Associated with the Development of Accelerated Knee Osteoarthritis: Data from the Osteoarthritis Initiative. Cartilage. 2021 12; 13(1_suppl):239S-248S.
Popovic T, Samaan MA, Link TM, Majumdar S, Souza RB. Patients with Symptomatic Hip Osteoarthritis Have Altered Kinematics during Stair Ambulation. PM R. 2021 02; 13(2):128-136.
Kransdorf MJ, Link TM, Palmer WE, Fitzhugh VA. Skeletal Radiology: the year in review 2019. Skeletal Radiol. 2020 Aug; 49(8):1179-1181.
Roemer FW, Demehri S, Omoumi P, Link TM, Kijowski R, Saarakkala S, Crema MD, Guermazi A. State of the Art: Imaging of Osteoarthritis-Revisited 2020. Radiology. 2020 07; 296(1):5-21.
Tibrewala R, Ozhinsky E, Shah R, Flament I, Crossley K, Srinivasan R, Souza R, Link TM, Pedoia V, Majumdar S. Computer-Aided Detection AI Reduces Interreader Variability in Grading Hip Abnormalities With MRI. J Magn Reson Imaging. 2020 10; 52(4):1163-1172.
Link TM, Kazakia G. Update on Imaging-Based Measurement of Bone Mineral Density and Quality. Curr Rheumatol Rep. 2020 04 09; 22(5):13.
Ashmeik W, Joseph GB, Nevitt MC, Lane NE, McCulloch CE, Link TM. Association of blood pressure with knee cartilage composition and structural knee abnormalities: data from the osteoarthritis initiative. Skeletal Radiol. 2020 Sep; 49(9):1359-1368.
von Schacky CE, Sohn JH, Liu F, Ozhinsky E, Jungmann PM, Nardo L, Posadzy M, Foreman SC, Nevitt MC, Link TM, Pedoia V. Development and Validation of a Multitask Deep Learning Model for Severity Grading of Hip Osteoarthritis Features on Radiographs. Radiology. 2020 04; 295(1):136-145.
Gutierrez LB, Link TM, Horvai AE, Joseph GB, O'Donnell RJ, Motamedi D. Secondary aneurysmal bone cysts and associated primary lesions: imaging features of 49 cases. Clin Imaging. 2020 Jun; 62:23-32.
Schirò S, Foreman SC, Bucknor M, Chin CT, Joseph GB, Link TM. Diagnostic Performance of CT-Guided Bone Biopsies in Patients with Suspected Osteomyelitis of the Appendicular and Axial Skeleton with a Focus on Clinical and Technical Factors Associated with Positive Microbiology Culture Results. J Vasc Interv Radiol. 2020 Mar; 31(3):464-472.
Nardo L, Abdelhafez YG, Acquafredda F, Schirò S, Wong AL, Sarohia D, Maroldi R, Darrow MA, Guindani M, Lee S, Zhang M, Moawad AW, Elsayes KM, Badawi RD, Link TM. Qualitative evaluation of MRI features of lipoma and atypical lipomatous tumor: results from a multicenter study. Skeletal Radiol. 2020 Jun; 49(6):1005-1014.
Foreman SC, Wu PH, Kuang R, John MD, Tien PC, Link TM, Krug R, Kazakia GJ. Factors associated with bone microstructural alterations assessed by HR-pQCT in long-term HIV-infected individuals. Bone. 2020 04; 133:115210.
Joseph GB, McCulloch CE, Nevitt MC, Foreman S, Liu F, Lane NE, Link TM. Associations between alcohol, smoking, and cartilage composition and knee joint morphology: Data from the Osteoarthritis Initiative. Osteoarthr Cartil Open. 2019 Nov-Dec; 1(1-2):100006.
Foreman SC, Zhang AL, Neumann J, von Schacky CE, Souza RB, Majumdar S, Link TM. Postoperative MRI Findings and Associated Pain Changes After Arthroscopic Surgery for Femoroacetabular Impingement. AJR Am J Roentgenol. 2020 01; 214(1):177-184.
Foreman SC, Gersing AS, von Schacky CE, Joseph GB, Neumann J, Lane NE, McCulloch CE, Nevitt MC, Link TM. Chondrocalcinosis is associated with increased knee joint degeneration over 4 years: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2020 02; 28(2):201-207.
Liao TC, Pedoia V, Neumann J, Link TM, Souza RB, Majumdar S. Extracting Voxel-Based Cartilage Relaxometry Features in Hip Osteoarthritis Subjects Using Principal Component Analysis. J Magn Reson Imaging. 2020 06; 51(6):1708-1719.
Liao TC, Samaan MA, Popovic T, Neumann J, Zhang AL, Link TM, Majumdar S, Souza RB. Abnormal Joint Loading During Gait in Persons With Hip Osteoarthritis Is Associated With Symptoms and Cartilage Lesions. J Orthop Sports Phys Ther. 2019 12; 49(12):917-924.
Heilmeier U, Mamoto K, Amano K, Eck B, Tanaka M, Bullen JA, Schwaiger BJ, Huebner JL, Stabler TV, Kraus VB, Ma CB, Link TM, Li X. Infrapatellar fat pad abnormalities are associated with a higher inflammatory synovial fluid cytokine profile in young adults following ACL tear. Osteoarthritis Cartilage. 2020 01; 28(1):82-91.
Tibrewala R, Bahroos E, Mehrabian H, Foreman SC, Link TM, Pedoia V, Majumdar S. [18 F]-Sodium Fluoride PET/MR Imaging for Bone-Cartilage Interactions in Hip Osteoarthritis: A Feasibility Study. J Orthop Res. 2019 12; 37(12):2671-2680.
Foreman SC, Ashmeik W, Baal JD, Han M, Bahroos E, von Schacky CE, Carl M, Krug R, Joseph GB, Link TM. Patients with Type 2 Diabetes Exhibit a More Mineralized Deep Cartilage Layer Compared with Nondiabetic Controls: A Pilot Study. Cartilage. 2021 12; 13(1_suppl):428S-436S.
Fields AJ, Battié MC, Herzog RJ, Jarvik JG, Krug R, Link TM, Lotz JC, O'Neill CW, Sharma A, ISSLS Degenerative Spinal Phenotypes Group. Measuring and reporting of vertebral endplate bone marrow lesions as seen on MRI (Modic changes): recommendations from the ISSLS Degenerative Spinal Phenotypes Group. Eur Spine J. 2019 10; 28(10):2266-2274.
Liao TC, Teng HL, Link TM, Majumdar S, Souza RB. Association Between Gait Kinetics and Symptomatic Progression in Persons With Patellofemoral With/Without Concurrent Tibiofemoral Osteoarthritis. J Orthop Res. 2019 12; 37(12):2593-2600.
Neumann J, Kern K, Sun D, Foreman SC, Joseph GB, Gersing AS, Nevitt MC, McCulloch CE, Quitzke A, Link TM. Cartilage degeneration post-meniscectomy performed for degenerative disease versus trauma: data from the Osteoarthritis Initiative. Skeletal Radiol. 2020 Feb; 49(2):231-240.
Foreman SC, Neumann J, Joseph GB, Nevitt MC, McCulloch CE, Lane NE, Link TM. Longitudinal MRI structural findings observed in accelerated knee osteoarthritis: data from the Osteoarthritis Initiative. Skeletal Radiol. 2019 Dec; 48(12):1949-1959.
Norman B, Pedoia V, Noworolski A, Link TM, Majumdar S. Applying Densely Connected Convolutional Neural Networks for Staging Osteoarthritis Severity from Plain Radiographs. J Digit Imaging. 2019 06; 32(3):471-477.
Wu PH, Gibbons M, Foreman SC, Carballido-Gamio J, Han M, Krug R, Liu J, Link TM, Kazakia GJ. Cortical bone vessel identification and quantification on contrast-enhanced MR images. Quant Imaging Med Surg. 2019 Jun; 9(6):928-941.
Liu Y, Foreman SC, Joseph GB, Neumann J, Tien PC, Li X, Lane NE, Nevitt MC, McCulloch CE, Link TM. Is treated HIV infection associated with knee cartilage degeneration and structural changes? A longitudinal study using data from the osteoarthritis initiative. BMC Musculoskelet Disord. 2019 May 04; 20(1):190.
Pedoia V, Lee J, Norman B, Link TM, Majumdar S. Diagnosing osteoarthritis from T2 maps using deep learning: an analysis of the entire Osteoarthritis Initiative baseline cohort. Osteoarthritis Cartilage. 2019 07; 27(7):1002-1010.
Baal JD, Pai JS, Chen WC, Joseph GB, O'Donnell RJ, Link TM. Factors Associated with Osteoid Osteoma Recurrence after CT-Guided Radiofrequency Ablation. J Vasc Interv Radiol. 2019 May; 30(5):744-751.
Gersing AS, Schwaiger BJ, Nevitt MC, Zarnowski J, Joseph GB, Feuerriegel G, Jungmann PM, Guimaraes JB, Facchetti L, McCulloch CE, Link TM. Weight loss regimen in obese and overweight individuals is associated with reduced cartilage degeneration: 96-month data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2019 06; 27(6):863-870.
Zhong Q, Pedoia V, Tanaka M, Neumann J, Link TM, Ma B, Lin J, Li X. 3D bone-shape changes and their correlations with cartilage T1ρ and T2 relaxation times and patient-reported outcomes over 3-years after ACL reconstruction. Osteoarthritis Cartilage. 2019 06; 27(6):915-921.
Kretzschmar M, Nevitt MC, Schwaiger BJ, Joseph GB, McCulloch CE, Link TM. Spatial distribution and temporal progression of T2 relaxation time values in knee cartilage prior to the onset of cartilage lesions - data from the Osteoarthritis Initiative (OAI). Osteoarthritis Cartilage. 2019 05; 27(5):737-745.
Shimizu T, Cruz A, Tanaka M, Mamoto K, Pedoia V, Burghardt AJ, Heilmeier U, Link TM, Graf J, Imboden JB, Li X. Structural Changes over a Short Period Are Associated with Functional Assessments in Rheumatoid Arthritis. J Rheumatol. 2019 07; 46(7):676-684.
Kretzschmar M, Heilmeier U, Foreman SC, Joseph GB, McCulloch CE, Nevitt MC, Link TM. Central osteophytes develop in cartilage with abnormal structure and composition: data from the Osteoarthritis Initiative cohort. Skeletal Radiol. 2019 Sep; 48(9):1357-1365.
Krug R, Joseph GB, Han M, Fields A, Cheung J, Mundada M, Bailey J, Rochette A, Ballatori A, McCulloch CE, McCormick Z, O'Neill C, Link TM, Lotz J. Associations between vertebral body fat fraction and intervertebral disc biochemical composition as assessed by quantitative MRI. J Magn Reson Imaging. 2019 10; 50(4):1219-1226.
Zaid M, Chavez MR, Carrasco AE, Zimel MN, Zhang AL, Horvai AE, Link TM, O'Donnell RJ. Cutibacterium (formerly Propionibacterium) acnes clavicular infection. J Bone Jt Infect. 2019; 4(1):40-49.
Link TM, Patel R. The need for short MRI examinations: A musculoskeletal perspective. J Magn Reson Imaging. 2019 Jun; 49(7):e49-e50.
Sun D, Neumann J, Joseph GB, Foreman S, Nevitt MC, McCulloch CE, Li X, Link TM. Introduction of an MR-based semi-quantitative score for assessing partial meniscectomy and relation to knee joint degenerative disease: data from the Osteoarthritis Initiative. Eur Radiol. 2019 Jun; 29(6):3262-3272.
Jungmann PM, Gersing AS, Baumann F, Holwein C, Braun S, Neumann J, Zarnowski J, Hofmann FC, Imhoff AB, Rummeny EJ, Link TM. Cartilage repair surgery prevents progression of knee degeneration. Knee Surg Sports Traumatol Arthrosc. 2019 Sep; 27(9):3001-3013.
Neumann J, Guimaraes JB, Heilmeier U, Joseph GB, Nevitt MC, McCulloch CE, Link TM. Diabetics show accelerated progression of knee cartilage and meniscal lesions: data from the osteoarthritis initiative. Skeletal Radiol. 2019 Jun; 48(6):919-930.
Inamdar G, Pedoia V, Rossi-Devries J, Samaan MA, Link TM, Souza RB, Majumdar S. MR study of longitudinal variations in proximal femur 3D morphological shape and associations with cartilage health in hip osteoarthritis. J Orthop Res. 2019 01; 37(1):161-170.
Pedoia V, Norman B, Mehany SN, Bucknor MD, Link TM, Majumdar S. 3D convolutional neural networks for detection and severity staging of meniscus and PFJ cartilage morphological degenerative changes in osteoarthritis and anterior cruciate ligament subjects. J Magn Reson Imaging. 2019 02; 49(2):400-410.
Berg-Johansen B, Jain D, Liebenberg EC, Fields AJ, Link TM, O'Neill CW, Lotz JC. Tidemark Avulsions are a Predominant Form of Endplate Irregularity. Spine (Phila Pa 1976). 2018 08; 43(16):1095-1101.
Grace T, Neumann J, Samaan MA, Souza RB, Majumdar S, Link TM, Zhang AL. Using the Scoring Hip Osteoarthritis with Magnetic Resonance Imaging (SHOMRI) system to assess intra-articular pathology in femoroacetabular impingement. J Orthop Res. 2018 11; 36(11):3064-3070.
Neumann J, Zhang AL, Schwaiger BJ, Samaan MA, Souza R, Foreman SC, Joseph GB, Grace T, Majumdar S, Link TM. Validation of scoring hip osteoarthritis with MRI (SHOMRI) scores using hip arthroscopy as a standard of reference. Eur Radiol. 2019 Feb; 29(2):578-587.
Heilmeier U, Wamba JM, Joseph GB, Darakananda K, Callan J, Neumann J, Link TM. Baseline knee joint effusion and medial femoral bone marrow edema, in addition to MRI-based T2 relaxation time and texture measurements of knee cartilage, can help predict incident total knee arthroplasty 4-7 years later: data from the Osteoarthritis Initiative. Skeletal Radiol. 2019 Jan; 48(1):89-101.
Baal JD, Horvai AE, Link TM. Progression of dialysis-related amyloidoma towards pathologic fracture. Skeletal Radiol. 2019 Feb; 48(2):301-306.
Grace T, Samaan MA, Souza RB, Link TM, Majumdar S, Zhang AL. Correlation of Patient Symptoms With Labral and Articular Cartilage Damage in Femoroacetabular Impingement. Orthop J Sports Med. 2018 Jun; 6(6):2325967118778785.
Joseph GB, Nevitt MC, McCulloch CE, Neumann J, Lynch JA, Heilmeier U, Lane NE, Link TM. Associations between molecular biomarkers and MR-based cartilage composition and knee joint morphology: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2018 08; 26(8):1070-1077.
Link TM. Editorial comment: the future of compositional MRI for cartilage. Eur Radiol. 2018 07; 28(7):2872-2873.
Teng HL, Pedoia V, Link TM, Majumdar S, Souza RB. Local associations between knee cartilage T1ρ and T2 relaxation times and patellofemoral joint stress during walking: A voxel-based relaxometry analysis. Knee. 2018 Jun; 25(3):406-416.
Neumann J, Hofmann FC, Heilmeier U, Ashmeik W, Tang K, Gersing AS, Schwaiger BJ, Nevitt MC, Joseph GB, Lane NE, McCulloch CE, Link TM. Type 2 diabetes patients have accelerated cartilage matrix degeneration compared to diabetes free controls: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2018 06; 26(6):751-761.
Link TM, Li X. Establishing compositional MRI of cartilage as a biomarker for clinical practice. Osteoarthritis Cartilage. 2018 09; 26(9):1137-1139.
Rosenthal DI, Kransdorf MJ, Link TM, Astrom G. Skeletal Radiology: The Year in Review 2017. Skeletal Radiol. 2018 03; 47(3):303-305.
Guimaraes JB, Facchetti L, Schwaiger BJ, Gersing AS, Li X, Link TM. Natural evolution of popliteomeniscal fascicle tears over 2 years and its association with lateral articular knee cartilage degeneration in patients with traumatic anterior cruciate ligament tear. Eur Radiol. 2018 Aug; 28(8):3542-3549.
Mok A, Rhead B, Holingue C, Shao X, Quach HL, Quach D, Sinclair E, Graf J, Imboden J, Link T, Harrison R, Chernitskiy V, Barcellos LF, Criswell LA. Hypomethylation of CYP2E1 and DUSP22 Promoters Associated With Disease Activity and Erosive Disease Among Rheumatoid Arthritis Patients. Arthritis Rheumatol. 2018 04; 70(4):528-536.
Knox J, Pedoia V, Wang A, Tanaka M, Joseph GB, Neumann J, Link TM, Li X, Ma CB. Longitudinal changes in MR T1ρ/T2 signal of meniscus and its association with cartilage T1p/T2 in ACL-injured patients. Osteoarthritis Cartilage. 2018 05; 26(5):689-696.
Crossley KM, Pandy MG, Majumdar S, Smith AJ, Agricola R, Semciw AI, Kemp JL, Heerey JJ, King MG, Lawrenson PR, Lin YC, Souza RB, Mosler AB, Link TM, Srinivasan R, Schache AG. Femoroacetabular impingement and hip OsteoaRthritis Cohort (FORCe): protocol for a prospective study. J Physiother. 2018 01; 64(1):55.
Joseph GB, McCulloch CE, Nevitt MC, Neumann J, Gersing AS, Kretzschmar M, Schwaiger BJ, Lynch JA, Heilmeier U, Lane NE, Link TM. Tool for osteoarthritis risk prediction (TOARP) over 8 years using baseline clinical data, X-ray, and MRI: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2018 06; 47(6):1517-1526.
Kumar D, Wyatt C, Lee S, Okazaki N, Chiba K, Link TM, Souza RB, Majumdar S. Sagittal plane walking patterns are related to MRI changes over 18-months in people with and without mild-moderate hip osteoarthritis. J Orthop Res. 2018 05; 36(5):1472-1477.
Guimaraes JB, Nevitt MC, McCulloch CE, Schwaiger BJ, Gersing AS, Facchetti L, Bucknor MD, Chanchek N, Liu F, Joseph GB, Link TM. Association of weight change with progression of meniscal intrasubstance degeneration over 48 months: Data from the Osteoarthritis Initiative. Eur Radiol. 2018 Mar; 28(3):953-962.
Shimizu T, Choi HJ, Heilmeier U, Tanaka M, Burghardt AJ, Gong J, Chanchek N, Link TM, Graf J, Imboden JB, Li X. Assessment of 3-month changes in bone microstructure under anti-TNFα therapy in patients with rheumatoid arthritis using high-resolution peripheral quantitative computed tomography (HR-pQCT). Arthritis Res Ther. 2017 Oct 04; 19(1):222.
Guimaraes JB, Zanoteli E, Link TM, de Camargo LV, Facchetti L, Nardo L, Fernandes ADRC. Sporadic Inclusion Body Myositis: MRI Findings and Correlation With Clinical and Functional Parameters. AJR Am J Roentgenol. 2017 Dec; 209(6):1340-1347.
Schwaiger BJ, Mbapte Wamba J, Gersing AS, Nevitt MC, Facchetti L, McCulloch CE, Link TM. Hyperintense signal alteration in the suprapatellar fat pad on MRI is associated with degeneration of the patellofemoral joint over 48 months: data from the Osteoarthritis Initiative. Skeletal Radiol. 2018 Mar; 47(3):329-339.
Hofmann FC, Neumann J, Heilmeier U, Joseph GB, Nevitt MC, McCulloch CE, Link TM. Conservatively treated knee injury is associated with knee cartilage matrix degeneration measured with MRI-based T2 relaxation times: data from the osteoarthritis initiative. Skeletal Radiol. 2018 Jan; 47(1):93-106.
Samaan MA, Pedoia V, Zhang AL, Gallo MC, Link TM, Souza RB, Majumdar S. A novel mr-based method for detection of cartilage delamination in femoroacetabular impingement patients. J Orthop Res. 2018 03; 36(3):971-978.
Chanchek N, Gersing AS, Schwaiger BJ, Nevitt MC, Neumann J, Joseph GB, Lane NE, Zarnowski J, Hofmann FC, Heilmeier U, McCulloch CE, Link TM. Association of diabetes mellitus and biochemical knee cartilage composition assessed by T2 relaxation time measurements: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2018 02; 47(2):380-390.
Holmes MG, Foss E, Joseph G, Foye A, Beckett B, Motamedi D, Youngren J, Thomas GV, Huang J, Aggarwal R, Alumkal JJ, Beer TM, Small EJ, Link TM. CT-Guided Bone Biopsies in Metastatic Castration-Resistant Prostate Cancer: Factors Predictive of Maximum Tumor Yield. J Vasc Interv Radiol. 2017 Aug; 28(8):1073-1081.e1.
Morgan TA, Piper SL, Lattanza LL, Goldstein RB, Link T, Motamedi D. Distal Forearm Fracture Open Reduction-Internal Fixation: Sonographic Detection of Hardware Malalignment and Associated Tendon Injuries Missed by Radiography. J Ultrasound Med. 2017 Oct; 36(10):2173-2177.
Gersing AS, Schwaiger BJ, Nevitt MC, Joseph GB, Chanchek N, Guimaraes JB, Mbapte Wamba J, Facchetti L, McCulloch CE, Link TM. Is Weight Loss Associated with Less Progression of Changes in Knee Articular Cartilage among Obese and Overweight Patients as Assessed with MR Imaging over 48 Months? Data from the Osteoarthritis Initiative. Radiology. 2017 08; 284(2):508-520.
Schwaiger BJ, Kopperdahl DL, Nardo L, Facchetti L, Gersing AS, Neumann J, Lee KJ, Keaveny TM, Link TM. Vertebral and femoral bone mineral density and bone strength in prostate cancer patients assessed in phantomless PET/CT examinations. Bone. 2017 Aug; 101:62-69.
Joseph GB, McCulloch CE, Nevitt MC, Gersing AS, Schwaiger BJ, Kretzschmar M, Heilmeier U, Link TM. Medial femur T2 Z-scores predict the probability of knee structural worsening over 4-8 years: Data from the osteoarthritis initiative. J Magn Reson Imaging. 2017 10; 46(4):1128-1136.
Samaan MA, Facchetti L, Pedoia V, Tanaka MS, Link TM, Souza RB, Ma CB, Li X. Cyclops lesions are associated with altered gait patterns and medial knee joint cartilage degeneration at 1 year after ACL-reconstruction. J Orthop Res. 2017 10; 35(10):2275-2281.
Amano K, Li AK, Pedoia V, Koff MF, Krych AJ, Link TM, Potter H, Rodeo S, Li X, Ma CB, Majumdar S, Arthritis Foundation-ACL Consortium. Effects of Surgical Factors on Cartilage Can Be Detected Using Quantitative Magnetic Resonance Imaging After Anterior Cruciate Ligament Reconstruction. Am J Sports Med. 2017 Apr; 45(5):1075-1084.
Garwood ER, Souza RB, Zhang A, Zhang AL, Ma CB, Link TM, Motamedi D. Axial traction magnetic resonance imaging (MRI) of the glenohumeral joint in healthy volunteers: initial experience. Clin Imaging. 2017 Mar - Apr; 42:178-182.
Link TM, Neumann J, Li X. Prestructural cartilage assessment using MRI. J Magn Reson Imaging. 2017 04; 45(4):949-965.
Samaan MA, Schwaiger BJ, Gallo MC, Sada K, Link TM, Zhang AL, Majumdar S, Souza RB. Joint Loading in the Sagittal Plane During Gait Is Associated With Hip Joint Abnormalities in Patients With Femoroacetabular Impingement. Am J Sports Med. 2017 Mar; 45(4):810-818.
Facchetti L, Schwaiger BJ, Gersing AS, Guimaraes JB, Nardo L, Majumdar S, Ma BC, Link TM, Li X, UCSF-P50-ACL Consortium, AF-ACL Consortium. Cyclops lesions detected by MRI are frequent findings after ACL surgical reconstruction but do not impact clinical outcome over 2 years. Eur Radiol. 2017 Aug; 27(8):3499-3508.
Jungmann PM, Baum T, Nevitt MC, Nardo L, Gersing AS, Lane NE, McCulloch CE, Rummeny EJ, Link TM. Degeneration in ACL Injured Knees with and without Reconstruction in Relation to Muscle Size and Fat Content-Data from the Osteoarthritis Initiative. PLoS One. 2016; 11(12):e0166865.
Gong J, Pedoia V, Facchetti L, Link TM, Ma CB, Li X. Bone marrow edema-like lesions (BMELs) are associated with higher T1ρ and T2 values of cartilage in anterior cruciate ligament (ACL)-reconstructed knees: a longitudinal study. Quant Imaging Med Surg. 2016 Dec; 6(6):661-670.
Guimaraes JB, Facchetti L, Schwaiger BJ, Gersing AS, Majumdar S, Ma BC, Li X, Link TM. Evolution of Intrameniscal Signal-Intensity Alterations Detected on MRI Over 24 Months in Patients With Traumatic Anterior Cruciate Ligament Tear. AJR Am J Roentgenol. 2017 Feb; 208(2):386-392.
Link TM, Heilmeier U. Bone Quality-Beyond Bone Mineral Density. Semin Musculoskelet Radiol. 2016 Jul; 20(3):269-278.
Samaan MA, Schwaiger BJ, Gallo MC, Link TM, Zhang AL, Majumdar S, Souza RB. Abnormal Joint Moment Distributions and Functional Performance During Sit-to-Stand in Femoroacetabular Impingement Patients. PM R. 2017 Jun; 9(6):563-570.
Gersing AS, Schwaiger BJ, Heilmeier U, Joseph GB, Facchetti L, Kretzschmar M, Lynch JA, McCulloch CE, Nevitt MC, Steinbach LS, Link TM. Evaluation of Chondrocalcinosis and Associated Knee Joint Degeneration Using MR Imaging: Data from the Osteoarthritis Initiative. Eur Radiol. 2017 Jun; 27(6):2497-2506.
Heilmeier U, Hackl M, Skalicky S, Weilner S, Schroeder F, Vierlinger K, Patsch JM, Baum T, Oberbauer E, Lobach I, Burghardt AJ, Schwartz AV, Grillari J, Link TM. Serum miRNA Signatures Are Indicative of Skeletal Fractures in Postmenopausal Women With and Without Type 2 Diabetes and Influence Osteogenic and Adipogenic Differentiation of Adipose Tissue-Derived Mesenchymal Stem Cells In Vitro. J Bone Miner Res. 2016 12; 31(12):2173-2192.
Ku E, Pedoia V, Tanaka M, Heilmeier U, Imboden J, Graf J, Link T, Li X. Evaluating radiocarpal cartilage matrix changes 3-months after anti-TNF treatment for rheumatoid arthritis using MR T1ρ imaging. J Magn Reson Imaging. 2017 05; 45(5):1514-1522.
Pedoia V, Su F, Amano K, Li Q, McCulloch CE, Souza RB, Link TM, Ma BC, Li X. Analysis of the articular cartilage T1ρ and T2 relaxation times changes after ACL reconstruction in injured and contralateral knees and relationships with bone shape. J Orthop Res. 2017 03; 35(3):707-717.
Kansagra AP, Wan JJ, Devulapalli KK, Horvai AE, O'Donnell RJ, Link TM. Malignant Transformation of an Aneurysmal Bone Cyst to Fibroblastic Osteosarcoma. Am J Orthop (Belle Mead NJ). 2016 Sep/Oct; 45(6):E367-E372.
Trivedi H, Link TM, O'Donnell RJ, Horvai AE, Motamedi D. Multiple hereditary exostoses: A pseudoaneurysm masquerading as tumor. J Radiol Case Rep. 2016 Aug; 10(8):50-59.
Gutierrez LB, Link T, Chaganti K, Motamedi D. Arterial calcification due to CD73 deficiency (ACDC): imaging manifestations of ectopic mineralization. Skeletal Radiol. 2016 Nov; 45(11):1583-7.
Burke C, Link T, O'Donnell RJ, Cho SJ, Motamedi D. Giant Cell Tumor of Bone: Documented Progression over 4 Years from Its Origin at the Metaphysis to the Articular Surface. Case Rep Radiol. 2016; 2016:9786925.
Li Q, Amano K, Link TM, Ma CB. Advanced Imaging in Osteoarthritis. Sports Health. 2016 Sep; 8(5):418-28.
Goldman LH, Tang K, Facchetti L, Heilmeier U, Joseph GB, Nevitt MC, McCulloch CE, Souza RB, Link TM. Role of thigh muscle cross-sectional area and strength in progression of knee cartilage degeneration over 48 months - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2016 12; 24(12):2082-2091.
Leeman JJ, Motamedi D, Wildman-Tobriner B, O'Donnell RJ, Link TM. Intra-articular osteoid osteoma at the femoral trochlea treated with osteochondral autograft transplantation. J Radiol Case Rep. 2016 Jun; 10(6):22-29.
Patel R, Eltgroth M, Souza R, Zhang CA, Majumdar S, Link TM, Motamedi D. Loaded versus unloaded magnetic resonance imaging (MRI) of the knee: Effect on meniscus extrusion in healthy volunteers and patients with osteoarthritis. Eur J Radiol Open. 2016; 3:100-7.
Samaan MA, Zhang AL, Gallo MC, Schwaiger BJ, Link TM, Souza RB, Majumdar S. Quantitative magnetic resonance arthrography in patients with femoroacetabular impingement. J Magn Reson Imaging. 2016 12; 44(6):1539-1545.
Heilmeier U, Cheng K, Pasco C, Parrish R, Nirody J, Patsch JM, Zhang CA, Joseph GB, Burghardt AJ, Schwartz AV, Link TM, Kazakia G. Cortical bone laminar analysis reveals increased midcortical and periosteal porosity in type 2 diabetic postmenopausal women with history of fragility fractures compared to fracture-free diabetics. Osteoporos Int. 2016 09; 27(9):2791-2802.
Schwaiger BJ, Gersing AS, Mbapte Wamba J, Nevitt MC, McCulloch CE, Link TM. Can Signal Abnormalities Detected with MR Imaging in Knee Articular Cartilage Be Used to Predict Development of Morphologic Cartilage Defects? 48-Month Data from the Osteoarthritis Initiative. Radiology. 2016 10; 281(1):158-67.
Teng HL, Calixto NE, MacLeod TD, Nardo L, Link TM, Majumdar S, Souza RB. Associations between patellofemoral joint cartilage T1ρ and T2 and knee flexion moment and impulse during gait in individuals with and without patellofemoral joint osteoarthritis. Osteoarthritis Cartilage. 2016 09; 24(9):1554-64.
Schwaiger BJ, Gersing AS, Lee S, Nardo L, Samaan MA, Souza RB, Link TM, Majumdar S. Longitudinal assessment of MRI in hip osteoarthritis using SHOMRI and correlation with clinical progression. Semin Arthritis Rheum. 2016 06; 45(6):648-55.
Kretzschmar M, Heilmeier U, Yu A, Joseph GB, Liu F, Solka M, McCulloch CE, Nevitt MC, Link TM. Longitudinal analysis of cartilage T2 relaxation times and joint degeneration in African American and Caucasian American women over an observation period of 6 years - data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2016 08; 24(8):1384-91.
Gallo MC, Wyatt C, Pedoia V, Kumar D, Lee S, Nardo L, Link TM, Souza RB, Majumdar S. T1ρ and T2 relaxation times are associated with progression of hip osteoarthritis. Osteoarthritis Cartilage. 2016 08; 24(8):1399-407.
Joseph GB, Hou SW, Nardo L, Heilmeier U, Nevitt MC, McCulloch CE, Link TM. MRI findings associated with development of incident knee pain over 48 months: data from the osteoarthritis initiative. Skeletal Radiol. 2016 May; 45(5):653-60.
Pedoia V, Majumdar S, Link TM. Segmentation of joint and musculoskeletal tissue in the study of arthritis. MAGMA. 2016 Apr; 29(2):207-21.
Heilmeier U, Youm J, Torabi S, Link TM. Osteoporosis Imaging in the Geriatric Patient. Curr Radiol Rep. 2016 Apr; 4(4).
Su F, Pedoia V, Teng HL, Kretzschmar M, Lau BC, McCulloch CE, Link TM, Ma CB, Li X. The association between MR T1ρ and T2 of cartilage and patient-reported outcomes after ACL injury and reconstruction. Osteoarthritis Cartilage. 2016 07; 24(7):1180-9.
Gersing AS, Solka M, Joseph GB, Schwaiger BJ, Heilmeier U, Feuerriegel G, Nevitt MC, McCulloch CE, Link TM. Progression of cartilage degeneration and clinical symptoms in obese and overweight individuals is dependent on the amount of weight loss: 48-month data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2016 07; 24(7):1126-34.
Gersing AS, Link TM. Imaging of Osteoarthritis in Geriatric Patients. Curr Radiol Rep. 2016 Jan; 4(1).
Kim C, Nevitt MC, Niu J, Clancy MM, Lane NE, Link TM, Vlad S, Tolstykh I, Jungmann PM, Felson DT, Guermazi A. Association of hip pain with radiographic evidence of hip osteoarthritis: diagnostic test study. BMJ. 2015 Dec 02; 351:h5983.
Wang A, Pedoia V, Su F, Abramson E, Kretzschmar M, Nardo L, Link TM, McCulloch CE, Jin C, Ma CB, Li X. MR T1ρ and T2 of meniscus after acute anterior cruciate ligament injuries. Osteoarthritis Cartilage. 2016 Apr; 24(4):631-9.
Liu J, Pedoia V, Heilmeier U, Ku E, Su F, Khanna S, Imboden J, Graf J, Link T, Li X. High-temporospatial-resolution dynamic contrast-enhanced (DCE) wrist MRI with variable-density pseudo-random circular Cartesian undersampling (CIRCUS) acquisition: evaluation of perfusion in rheumatoid arthritis patients. NMR Biomed. 2016 Jan; 29(1):15-23.
Nardo L, Han M, Kretzschmar M, Guindani M, Koch K, Vail T, Krug R, Link TM. Erratum to: Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla. Skeletal Radiol. 2015 Nov; 44(11):1617.
Joseph GB, Hilton JF, Jungmann PM, Lynch JA, Lane NE, Liu F, McCulloch CE, Tolstykh I, Link TM, Nevitt MC. Do persons with asymmetric hip pain or radiographic hip OA have worse pain and structure outcomes in the knee opposite the more affected hip? Data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2016 Mar; 24(3):427-35.
Wyatt C, Guha A, Venkatachari A, Li X, Krug R, Kelley DE, Link T, Majumdar S. Improved differentiation between knees with cartilage lesions and controls using 7T relaxation time mapping. J Orthop Translat. 2015 Oct; 3(4):197-204.
Hackney LA, Lee MH, Joseph GB, Vail TP, Link TM. Subchondral insufficiency fractures of the femoral head: associated imaging findings and predictors of clinical progression. Eur Radiol. 2016 Jun; 26(6):1929-41.
Kretzschmar M, Lin W, Nardo L, Joseph GB, Dunlop DD, Heilmeier U, Nevitt MC, Alizai H, McCulloch CE, Lynch JA, Link TM. Association of Physical Activity Measured by Accelerometer, Knee Joint Abnormalities, and Cartilage T2 Measurements Obtained From 3T Magnetic Resonance Imaging: Data From the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2015 Sep; 67(9):1272-1280.
Link TM, Schwaiger BJ, Zhang AL. Regional Articular Cartilage Abnormalities of the Hip. AJR Am J Roentgenol. 2015 Sep; 205(3):502-12.
Plett SK, Hackney LA, Heilmeier U, Nardo L, Yu A, Zhang CA, Link TM. Femoral condyle insufficiency fractures: associated clinical and morphological findings and impact on outcome. Skeletal Radiol. 2015 Dec; 44(12):1785-94.
Calixto NE, Kumar D, Subburaj K, Singh J, Schooler J, Nardo L, Li X, Souza RB, Link TM, Majumdar S. Zonal differences in meniscus MR relaxation times in response to in vivo static loading in knee osteoarthritis. J Orthop Res. 2016 Feb; 34(2):249-61.
Samaan MA, Teng HL, Kumar D, Lee S, Link TM, Majumdar S, Souza RB. Acetabular cartilage defects cause altered hip and knee joint coordination variability during gait. Clin Biomech (Bristol, Avon). 2015 Dec; 30(10):1202-9.
Kumar D, Souza RB, Subburaj K, MacLeod TD, Singh J, Calixto NE, Nardo L, Link TM, Li X, Lane NE, Majumdar S. Are There Sex Differences in Knee Cartilage Composition and Walking Mechanics in Healthy and Osteoarthritis Populations? Clin Orthop Relat Res. 2015 Aug; 473(8):2548-58.
Nardo L, Parimi N, Liu F, Lee S, Jungmann PM, Nevitt MC, Link TM, Lane NE, Osteoporotic Fractures in Men (MrOS) Research Group. Femoroacetabular Impingement: Prevalent and Often Asymptomatic in Older Men: The Osteoporotic Fractures in Men Study. Clin Orthop Relat Res. 2015 Aug; 473(8):2578-86.
Nardo L, Han M, Kretzschmar M, Kretschmar M, Guindani M, Koch K, Vail T, Krug R, Link TM. Metal artifact suppression at the hip: diagnostic performance at 3.0 T versus 1.5 Tesla. Skeletal Radiol. 2015 Nov; 44(11):1609-16.
Teng HL, MacLeod TD, Link TM, Majumdar S, Souza RB. Higher Knee Flexion Moment During the Second Half of the Stance Phase of Gait Is Associated With the Progression of Osteoarthritis of the Patellofemoral Joint on Magnetic Resonance Imaging. J Orthop Sports Phys Ther. 2015 Sep; 45(9):656-64.
Guha A, Wyatt C, Karampinos DC, Nardo L, Link TM, Majumdar S. Spatial variations in magnetic resonance-based diffusion of articular cartilage in knee osteoarthritis. Magn Reson Imaging. 2015 Nov; 33(9):1051-1058.
Jungmann PM, Brucker PU, Baum T, Link TM, Foerschner F, Minzlaff P, Banke IJ, Saier T, Imhoff AB, Rummeny EJ, Bauer JS. Bilateral cartilage T2 mapping 9 years after Mega-OATS implantation at the knee: a quantitative 3T MRI study. Osteoarthritis Cartilage. 2015 Dec; 23(12):2119-2128.
Link TM. Radiology of Osteoporosis. Can Assoc Radiol J. 2016 Feb; 67(1):28-40.
Wyatt C, Kumar D, Subburaj K, Lee S, Nardo L, Narayanan D, Lansdown D, Vail T, Link TM, Souza RB, Majumdar S. Cartilage T1ρ and T2 Relaxation Times in Patients With Mild-to-Moderate Radiographic Hip Osteoarthritis. Arthritis Rheumatol. 2015 Jun; 67(6):1548-56.
Gold GE, Cicuttini F, Crema MD, Eckstein F, Guermazi A, Kijowski R, Link TM, Maheu E, Martel-Pelletier J, Miller CG, Pelletier JP, Peterfy CG, Potter HG, Roemer FW, Hunter DJ. OARSI Clinical Trials Recommendations: Hip imaging in clinical trials in osteoarthritis. Osteoarthritis Cartilage. 2015 May; 23(5):716-31.
Hunter DJ, Altman RD, Cicuttini F, Crema MD, Duryea J, Eckstein F, Guermazi A, Kijowski R, Link TM, Martel-Pelletier J, Miller CG, Mosher TJ, Ochoa-Albíztegui RE, Pelletier JP, Peterfy C, Raynauld JP, Roemer FW, Totterman SM, Gold GE. OARSI Clinical Trials Recommendations: Knee imaging in clinical trials in osteoarthritis. Osteoarthritis Cartilage. 2015 May; 23(5):698-715.
Yu A, Heilmeier U, Kretzschmar M, Joseph GB, Liu F, Liebl H, McCulloch CE, Nevitt MC, Lane NE, Link TM. Racial differences in biochemical knee cartilage composition between African-American and Caucasian-American women with 3 T MR-based T2 relaxation time measurements--data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2015 Sep; 23(9):1595-604.
Yang H, Yu A, Burghardt AJ, Virayavanich W, Link TM, Imboden JB, Li X. Quantitative characterization of metacarpal and radial bone in rheumatoid arthritis using high resolution- peripheral quantitative computed tomography. Int J Rheum Dis. 2017 Mar; 20(3):353-362.
Lee S, Lucas RM, Lansdown DA, Nardo L, Lai A, Link TM, Krug R, Ma CB. Magnetic resonance rotator cuff fat fraction and its relationship with tendon tear severity and subject characteristics. J Shoulder Elbow Surg. 2015 Sep; 24(9):1442-51.
Jungmann PM, Nevitt MC, Baum T, Liebl H, Nardo L, Liu F, Lane NE, McCulloch CE, Link TM. Relationship of unilateral total hip arthroplasty (THA) to contralateral and ipsilateral knee joint degeneration - a longitudinal 3T MRI study from the Osteoarthritis Initiative (OAI). Osteoarthritis Cartilage. 2015 Jul; 23(7):1144-53.
Hong CW, Hsiao EC, Horvai AE, Link TM. Chronic recurrent multifocal osteomyelitis with an atypical presentation in an adult man. Skeletal Radiol. 2015 Sep; 44(9):1359-64.
Teng HL, MacLeod TD, Kumar D, Link TM, Majumdar S, Souza RB. Individuals with isolated patellofemoral joint osteoarthritis exhibit higher mechanical loading at the knee during the second half of the stance phase. Clin Biomech (Bristol, Avon). 2015 May; 30(4):383-90.
Nirody JA, Cheng KP, Parrish RM, Burghardt AJ, Majumdar S, Link TM, Kazakia GJ. Spatial distribution of intracortical porosity varies across age and sex. Bone. 2015 Jun; 75:88-95.
Kretzschmar M, Nardo L, Han MM, Heilmeier U, Sam C, Joseph GB, Koch KM, Krug R, Link TM. Metal artefact suppression at 3 T MRI: comparison of MAVRIC-SL with conventional fast spin echo sequences in patients with Hip joint arthroplasty. Eur Radiol. 2015 Aug; 25(8):2403-11.
Kumar D, Wyatt C, Chiba K, Lee S, Nardo L, Link TM, Majumdar S, Souza RB. Anatomic correlates of reduced hip extension during walking in individuals with mild-moderate radiographic hip osteoarthritis. J Orthop Res. 2015 Apr; 33(4):527-34.
Joseph GB, McCulloch CE, Nevitt MC, Heilmeier U, Nardo L, Lynch JA, Liu F, Baum T, Link TM. A reference database of cartilage 3 T MRI T2 values in knees without diagnostic evidence of cartilage degeneration: data from the osteoarthritis initiative. Osteoarthritis Cartilage. 2015 Jun; 23(6):897-905.
Heilmeier U, Carpenter DR, Patsch JM, Harnish R, Joseph GB, Burghardt AJ, Baum T, Schwartz AV, Lang TF, Link TM. Volumetric femoral BMD, bone geometry, and serum sclerostin levels differ between type 2 diabetic postmenopausal women with and without fragility fractures. Osteoporos Int. 2015 Apr; 26(4):1283-93.
Bucknor MD, Nardo L, Joseph GB, Alizai H, Srikhum W, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Association of cartilage degeneration with four year weight gain--3T MRI data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2015 Apr; 23(4):525-31.
Yang H, Rivoire J, Hoppe M, Srikhum W, Imboden J, Link TM, Li X. Computer-aided and manual quantifications of MRI synovitis, bone marrow edema-like lesions, erosion and cartilage loss in rheumatoid arthritis of the wrist. Skeletal Radiol. 2015 Apr; 44(4):539-47.
Lance V, Heilmeier UR, Joseph GB, Steinbach L, Ma B, Link TM. MR imaging characteristics and clinical symptoms related to displaced meniscal flap tears. Skeletal Radiol. 2015 Mar; 44(3):375-84.
Kumar D, Souza RB, Singh J, Calixto NE, Nardo L, Link TM, Li X, Majumdar S. Physical activity and spatial differences in medial knee T1rho and t2 relaxation times in knee osteoarthritis. J Orthop Sports Phys Ther. 2014 Dec; 44(12):964-72.
Bucknor MD, Rieke V, Seo Y, Horvai AE, Hawkins RA, Majumdar S, Link TM, Saeed M. Bone remodeling after MR imaging-guided high-intensity focused ultrasound ablation: evaluation with MR imaging, CT, Na(18)F-PET, and histopathologic examination in a swine model. Radiology. 2015 Feb; 274(2):387-94.
Lee CH, Srikhum W, Burghardt AJ, Virayavanich W, Imboden JB, Link TM, Li X. Correlation of structural abnormalities of the wrist and metacarpophalangeal joints evaluated by high-resolution peripheral quantitative computed tomography, 3 Tesla magnetic resonance imaging and conventional radiographs in rheumatoid arthritis. Int J Rheum Dis. 2015 Jul; 18(6):628-39.
Lee S, Nardo L, Kumar D, Wyatt CR, Souza RB, Lynch J, McCulloch CE, Majumdar S, Lane NE, Link TM. Scoring hip osteoarthritis with MRI (SHOMRI): A whole joint osteoarthritis evaluation system. J Magn Reson Imaging. 2015 Jun; 41(6):1549-57.
Gupta R, Virayavanich W, Kuo D, Su F, Link T, Ma B, Li X. MR T(1)ρ quantification of cartilage focal lesions in acutely injured knees: correlation with arthroscopic evaluation. Magn Reson Imaging. 2014 Dec; 32(10):1290-6.
Teruel JR, Burghardt AJ, Rivoire J, Srikhum W, Noworolski SM, Link TM, Imboden JB, Li X. Bone structure and perfusion quantification of bone marrow edema pattern in the wrist of patients with rheumatoid arthritis: a multimodality study. J Rheumatol. 2014 Sep; 41(9):1766-73.
Zhang AL, Gates CH, Link TM, Ma CB. Abnormal origins of the long head of the biceps tendon can lead to rotator cuff pathology: a report of two cases. Skeletal Radiol. 2014 Nov; 43(11):1621-6.
Liebl H, Heilmeier U, Lee S, Nardo L, Patsch J, Schuppert C, Han M, Rondak IC, Banerjee S, Koch K, Link TM, Krug R. In vitro assessment of knee MRI in the presence of metal implants comparing MAVRIC-SL and conventional fast spin echo sequences at 1.5 and 3 T field strength. J Magn Reson Imaging. 2015 May; 41(5):1291-9.
Link TM, Lang TF. Axial QCT: clinical applications and new developments. J Clin Densitom. 2014 Oct-Dec; 17(4):438-48.
Jungmann PM, Baum T, Bauer JS, Karampinos DC, Erdle B, Link TM, Li X, Trattnig S, Rummeny EJ, Woertler K, Welsch GH. Cartilage repair surgery: outcome evaluation by using noninvasive cartilage biomarkers based on quantitative MRI techniques? Biomed Res Int. 2014; 2014:840170.
Souza RB, Kumar D, Calixto N, Singh J, Schooler J, Subburaj K, Li X, Link TM, Majumdar S. Response of knee cartilage T1rho and T2 relaxation times to in vivo mechanical loading in individuals with and without knee osteoarthritis. Osteoarthritis Cartilage. 2014 Oct; 22(10):1367-76.
Eckstein F, Kwoh CK, Link TM, OAI investigators. Imaging research results from the osteoarthritis initiative (OAI): a review and lessons learned 10 years after start of enrolment. Ann Rheum Dis. 2014 Jul; 73(7):1289-300.
Serebrakian AT, Poulos T, Liebl H, Joseph GB, Lai A, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Weight loss over 48 months is associated with reduced progression of cartilage T2 relaxation time values: data from the osteoarthritis initiative. J Magn Reson Imaging. 2015 May; 41(5):1272-1280.
Yang CC, Nagarajan MB, Huber MB, Carballido-Gamio J, Bauer JS, Baum T, Eckstein F, Lochmüller EM, Link TM, Wismüller A. Predicting the Biomechanical Strength of Proximal Femur Specimens with Minkowski Functionals and Support Vector Regression. Proc SPIE Int Soc Opt Eng. 2014 Mar 13; 9038.
Liebl H, Joseph G, Nevitt MC, Singh N, Heilmeier U, Subburaj K, Jungmann PM, McCulloch CE, Lynch JA, Lane NE, Link TM. Early T2 changes predict onset of radiographic knee osteoarthritis: data from the osteoarthritis initiative. Ann Rheum Dis. 2015 Jul; 74(7):1353-9.
Kazakia GJ, Tjong W, Nirody JA, Burghardt AJ, Carballido-Gamio J, Patsch JM, Link T, Feeley BT, Ma CB. The influence of disuse on bone microstructure and mechanics assessed by HR-pQCT. Bone. 2014 Jun; 63:132-40.
Kumar D, Dillon A, Nardo L, Link TM, Majumdar S, Souza RB. Differences in the association of hip cartilage lesions and cam-type femoroacetabular impingement with movement patterns: a preliminary study. PM R. 2014 Aug; 6(8):681-9.
Alizai H, Virayavanich W, Joseph GB, Nardo L, Liu F, Liebl H, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Cartilage lesion score: comparison of a quantitative assessment score with established semiquantitative MR scoring systems. Radiology. 2014 May; 271(2):479-87.
Yang CC, Nagarajan MB, Huber MB, Carballido-Gamio J, Bauer JS, Baum T, Eckstein F, Lochmüller E, Majumdar S, Link TM, Wismüller A. Improving bone strength prediction in human proximal femur specimens through geometrical characterization of trabecular bone microarchitecture and support vector regression. J Electron Imaging. 2014 Feb 04; 23(1):013013.
Kumar D, Karampinos DC, MacLeod TD, Lin W, Nardo L, Li X, Link TM, Majumdar S, Souza RB. Quadriceps intramuscular fat fraction rather than muscle size is associated with knee osteoarthritis. Osteoarthritis Cartilage. 2014 Feb; 22(2):226-34.
Subburaj K, Souza RB, Wyman BT, Le Graverand-Gastineau MP, Li X, Link TM, Majumdar S. Changes in MR relaxation times of the meniscus with acute loading: an in vivo pilot study in knee osteoarthritis. J Magn Reson Imaging. 2015 Feb; 41(2):536-43.
Jungmann PM, Liu F, Link TM. What has imaging contributed to the epidemiological understanding of osteoarthritis? Skeletal Radiol. 2014 Mar; 43(3):271-5.
Jungmann PM, Kraus MS, Alizai H, Nardo L, Baum T, Nevitt MC, McCulloch CE, Joseph GB, Lynch JA, Link TM. Association of metabolic risk factors with cartilage degradation assessed by T2 relaxation time at the knee: data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2013 Dec; 65(12):1942-50.
Thevenot J, Hirvasniemi J, Finnilä M, Pulkkinen P, Kuhn V, Link T, Eckstein F, Jämsä T, Saarakkala S. Trabecular homogeneity index derived from plain radiograph to evaluate bone quality. J Bone Miner Res. 2013 Dec; 28(12):2584-91.
Bauer JS, Sidorenko I, Mueller D, Baum T, Issever AS, Eckstein F, Rummeny EJ, Link TM, Raeth CW. Prediction of bone strength by μCT and MDCT-based finite-element-models: how much spatial resolution is needed? Eur J Radiol. 2014 Jan; 83(1):e36-42.
Bucknor MD, Rieke V, Do L, Majumdar S, Link TM, Saeed M. MRI-guided high-intensity focused ultrasound ablation of bone: evaluation of acute findings with MR and CT imaging in a swine model. J Magn Reson Imaging. 2014 Nov; 40(5):1174-80.
Schooler J, Kumar D, Nardo L, McCulloch C, Li X, Link TM, Majumdar S. Longitudinal evaluation of T1ρ and T2 spatial distribution in osteoarthritic and healthy medial knee cartilage. Osteoarthritis Cartilage. 2014 Jan; 22(1):51-62.
Kumar D, Subburaj K, Lin W, Karampinos DC, McCulloch CE, Li X, Link TM, Souza RB, Majumdar S. Quadriceps and hamstrings morphology is related to walking mechanics and knee cartilage MRI relaxation times in young adults. J Orthop Sports Phys Ther. 2013 Dec; 43(12):881-90.
Solomon DA, Antonescu CR, Link TM, O'Donnell RJ, Folpe AL, Horvai AE. Hemosiderotic fibrolipomatous tumor, not an entirely benign entity. Am J Surg Pathol. 2013 Oct; 37(10):1627-30.
Marsh M, Souza RB, Wyman BT, Hellio Le Graverand MP, Subburaj K, Link TM, Majumdar S. Differences between X-ray and MRI-determined knee cartilage thickness in weight-bearing and non-weight-bearing conditions. Osteoarthritis Cartilage. 2013 Dec; 21(12):1876-85.
Nardo L, Karampinos DC, Lansdown DA, Carballido-Gamio J, Lee S, Maroldi R, Ma CB, Link TM, Krug R. Quantitative assessment of fat infiltration in the rotator cuff muscles using water-fat MRI. J Magn Reson Imaging. 2014 May; 39(5):1178-85.
Räth C, Baum T, Monetti R, Sidorenko I, Wolf P, Eckstein F, Matsuura M, Lochmüller EM, Zysset PK, Rummeny EJ, Link TM, Bauer JS. Scaling relations between trabecular bone volume fraction and microstructure at different skeletal sites. Bone. 2013 Dec; 57(2):377-83.
Jungmann PM, Kraus MS, Nardo L, Liebl H, Alizai H, Joseph GB, Liu F, Lynch J, McCulloch CE, Nevitt MC, Link TM. T(2) relaxation time measurements are limited in monitoring progression, once advanced cartilage defects at the knee occur: longitudinal data from the osteoarthritis initiative. J Magn Reson Imaging. 2013 Dec; 38(6):1415-24.
Virayavanich W, Alizai H, Baum T, Nardo L, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Association of frequent knee bending activity with focal knee lesions detected with 3T magnetic resonance imaging: data from the osteoarthritis initiative. Arthritis Care Res (Hoboken). 2013 Sep; 65(9):1441-8.
Chaichana KL, Gadkaree S, Rao K, Link T, Rigamonti D, Purtell M, Browner I, Weingart J, Olivi A, Gallia G, Bettegowda C, Brem H, Lim M, Quinones-Hinojosa A. Patients undergoing surgery of intracranial metastases have different outcomes based on their primary pathology. Neurol Res. 2013 Dec; 35(10):1059-69.
Patsch JM, Zulliger MA, Vilayphou N, Samelson EJ, Cejka D, Diarra D, Berzaczy G, Burghardt AJ, Link TM, Weber M, Loewe C. Quantification of lower leg arterial calcifications by high-resolution peripheral quantitative computed tomography. Bone. 2014 Jan; 58:42-7.
Kumar D, Wyatt CR, Lee S, Nardo L, Link TM, Majumdar S, Souza RB. Association of cartilage defects, and other MRI findings with pain and function in individuals with mild-moderate radiographic hip osteoarthritis and controls. Osteoarthritis Cartilage. 2013 Nov; 21(11):1685-92.
Patsch JM, Li X, Baum T, Yap SP, Karampinos DC, Schwartz AV, Link TM. Bone marrow fat composition as a novel imaging biomarker in postmenopausal women with prevalent fragility fractures. J Bone Miner Res. 2013 Aug; 28(8):1721-8.
Bucknor MD, Gross AJ, Link TM. Voriconazole-induced periostitis in two post-transplant patients. J Radiol Case Rep. 2013 Aug; 7(8):10-7.
Baum T, Joseph GB, Karampinos DC, Jungmann PM, Link TM, Bauer JS. Cartilage and meniscal T2 relaxation time as non-invasive biomarker for knee osteoarthritis and cartilage repair procedures. Osteoarthritis Cartilage. 2013 Oct; 21(10):1474-84.
Burghardt AJ, Lee CH, Kuo D, Majumdar S, Imboden JB, Link TM, Li X. Quantitative in vivo HR-pQCT imaging of 3D wrist and metacarpophalangeal joint space width in rheumatoid arthritis. Ann Biomed Eng. 2013 Dec; 41(12):2553-64.
Nardo L, Sandman DN, Virayavanich W, Zhang L, Souza RB, Steinbach L, Guindani M, Link TM. Bone marrow changes related to disuse. Eur Radiol. 2013 Dec; 23(12):3422-31.
Lin W, Alizai H, Joseph GB, Srikhum W, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Physical activity in relation to knee cartilage T2 progression measured with 3 T MRI over a period of 4 years: data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2013 Oct; 21(10):1558-66.
Jungmann PM, Tham SC, Liebl H, Nevitt MC, McCulloch CE, Lynch J, Link TM. Association of trochlear dysplasia with degenerative abnormalities in the knee: data from the Osteoarthritis Initiative. Skeletal Radiol. 2013 Oct; 42(10):1383-92.
Su F, Hilton JF, Nardo L, Wu S, Liang F, Link TM, Ma CB, Li X. Cartilage morphology and T1ρ and T2 quantification in ACL-reconstructed knees: a 2-year follow-up. Osteoarthritis Cartilage. 2013 Aug; 21(8):1058-67.
Subburaj K, Valentinitsch A, Dillon AB, Joseph GB, Li X, Link TM, Vail TP, Majumdar S. Regional variations in MR relaxation of hip joint cartilage in subjects with and without femoralacetabular impingement. Magn Reson Imaging. 2013 Sep; 31(7):1129-36.
Baum T, Gräbeldinger M, Räth C, Garcia EG, Burgkart R, Patsch JM, Rummeny EJ, Link TM, Bauer JS. Trabecular bone structure analysis of the spine using clinical MDCT: can it predict vertebral bone strength? J Bone Miner Metab. 2014 Jan; 32(1):56-64.
Chundru R, Baum T, Nardo L, Nevitt MC, Lynch J, McCulloch CE, Link TM. Focal knee lesions in knee pairs of asymptomatic and symptomatic subjects with OA risk factors--data from the Osteoarthritis Initiative. Eur J Radiol. 2013 Aug; 82(8):e367-73.
Yang CC, Nagarajan MB, Huber MB, Carballido-Gamio J, Bauer JS, Baum T, Eckstein F, Lochmüller E, Majumdar S, Link TM, Wismüller A. Predicting the Biomechanical Strength of Proximal Femur Specimens through High Dimensional Geometric Features and Support Vector Regression. Proc SPIE Int Soc Opt Eng. 2013 Mar; 8672.
Srikhum W, Virayavanich W, Burghardt AJ, Yu A, Link TM, Imboden JB, Li X. Quantitative and semiquantitative bone erosion assessment on high-resolution peripheral quantitative computed tomography in rheumatoid arthritis. J Rheumatol. 2013 Apr; 40(4):408-16.
Patsch JM, Burghardt AJ, Yap SP, Baum T, Schwartz AV, Joseph GB, Link TM. Increased cortical porosity in type 2 diabetic postmenopausal women with fragility fractures. J Bone Miner Res. 2013 Feb; 28(2):313-24.
Theologis AA, Haughom B, Liang F, Zhang Y, Majumdar S, Link TM, Ma CB, Li X. Comparison of T1rho relaxation times between ACL-reconstructed knees and contralateral uninjured knees. Knee Surg Sports Traumatol Arthrosc. 2014 Feb; 22(2):298-307.
Valentinitsch A, Patsch JM, Burghardt AJ, Link TM, Majumdar S, Fischer L, Schueller-Weidekamm C, Resch H, Kainberger F, Langs G. Computational identification and quantification of trabecular microarchitecture classes by 3-D texture analysis-based clustering. Bone. 2013 May; 54(1):133-40.
Baum T, Joseph GB, Nardo L, Virayavanich W, Arulanandan A, Alizai H, Carballido-Gamio J, Nevitt MC, Lynch J, McCulloch CE, Link TM. Correlation of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with body mass index: thirty-six-month followup data from a longitudinal, observational multicenter study. Arthritis Care Res (Hoboken). 2013 Jan; 65(1):23-33.
Ries MD, Link TM. Monitoring and risk of progression of osteolysis after total hip arthroplasty. Instr Course Lect. 2013; 62:207-14.
Nejadnik H, Henning TD, Do T, Sutton EJ, Baehner F, Horvai A, Sennino B, McDonald D, Meier R, Misselwitz B, Link TM, Daldrup-Link HE. MR imaging features of gadofluorine-labeled matrix-associated stem cell implants in cartilage defects. PLoS One. 2012; 7(12):e49971.
Srikhum W, Nardo L, Karampinos DC, Melkus G, Poulos T, Steinbach LS, Link TM. Magnetic resonance imaging of ankle tendon pathology: benefits of additional axial short-tau inversion recovery imaging to reduce magic angle effects. Skeletal Radiol. 2013 Apr; 42(4):499-510.
Karampinos DC, Melkus G, Shepherd TM, Banerjee S, Saritas EU, Shankaranarayanan A, Hess CP, Link TM, Dillon WP, Majumdar S. Diffusion tensor imaging and T2 relaxometry of bilateral lumbar nerve roots: feasibility of in-plane imaging. NMR Biomed. 2013 Jun; 26(6):630-7.
Baum T, Kutscher M, Müller D, Räth C, Eckstein F, Lochmüller EM, Rummeny EJ, Link TM, Bauer JS. Cortical and trabecular bone structure analysis at the distal radius-prediction of biomechanical strength by DXA and MRI. J Bone Miner Metab. 2013 Mar; 31(2):212-21.
Ries MD, Link TM. Monitoring and risk of progression of osteolysis after total hip arthroplasty. J Bone Joint Surg Am. 2012 Nov 21; 94(22):2097-105.
Souza RB, Feeley BT, Zarins ZA, Link TM, Li X, Majumdar S. T1rho MRI relaxation in knee OA subjects with varying sizes of cartilage lesions. Knee. 2013 Mar; 20(2):113-9.
Jungmann PM, Li X, Nardo L, Subburaj K, Lin W, Ma CB, Majumdar S, Link TM. Do cartilage repair procedures prevent degenerative meniscus changes?: longitudinal t1ρ and morphological evaluation with 3.0-T MRI. Am J Sports Med. 2012 Dec; 40(12):2700-8.
Valentinitsch A, Karampinos DC, Alizai H, Subburaj K, Kumar D, Link TM, Majumdar S. Automated unsupervised multi-parametric classification of adipose tissue depots in skeletal muscle. J Magn Reson Imaging. 2013 Apr; 37(4):917-27.
Prasad AP, Nardo L, Schooler J, Joseph GB, Link TM. T₁ρ and T₂ relaxation times predict progression of knee osteoarthritis. Osteoarthritis Cartilage. 2013 Jan; 21(1):69-76.
Kumar D, Schooler J, Zuo J, McCulloch CE, Nardo L, Link TM, Li X, Majumdar S. Trabecular bone structure and spatial differences in articular cartilage MR relaxation times in individuals with posterior horn medial meniscal tears. Osteoarthritis Cartilage. 2013 Jan; 21(1):86-93.
Nardo L, Alizai H, Virayavanich W, Liu F, Hernandez A, Lynch JA, Nevitt MC, McCulloch CE, Lane NE, Link TM. Lumbosacral transitional vertebrae: association with low back pain. Radiology. 2012 Nov; 265(2):497-503.
Baum T, Dütsch Y, Müller D, Monetti R, Sidorenko I, Räth C, Rummeny EJ, Link TM, Bauer JS. Reproducibility of trabecular bone structure measurements of the distal radius at 1.5 and 3.0 T magnetic resonance imaging. J Comput Assist Tomogr. 2012 Sep-Oct; 36(5):623-6.
Stehling C, Souza RB, Hellio Le Graverand MP, Wyman BT, Li X, Majumdar S, Link TM. Loading of the knee during 3.0T MRI is associated with significantly increased medial meniscus extrusion in mild and moderate osteoarthritis. Eur J Radiol. 2012 Aug; 81(8):1839-45.
Koivumäki JE, Thevenot J, Pulkkinen P, Kuhn V, Link TM, Eckstein F, Jämsä T. Cortical bone finite element models in the estimation of experimentally measured failure loads in the proximal femur. Bone. 2012 Oct; 51(4):737-40.
Subburaj K, Kumar D, Souza RB, Alizai H, Li X, Link TM, Majumdar S. The acute effect of running on knee articular cartilage and meniscus magnetic resonance relaxation times in young healthy adults. Am J Sports Med. 2012 Sep; 40(9):2134-41.
Henning TD, Gawande R, Khurana A, Tavri S, Mandrussow L, Golovko D, Horvai A, Sennino B, McDonald D, Meier R, Wendland M, Derugin N, Link TM, Daldrup-Link HE. Magnetic resonance imaging of ferumoxide-labeled mesenchymal stem cells in cartilage defects: in vitro and in vivo investigations. Mol Imaging. 2012 Jun; 11(3):197-209.
Joseph GB, Baum T, Alizai H, Carballido-Gamio J, Nardo L, Virayavanich W, Lynch JA, Nevitt MC, McCulloch CE, Majumdar S, Link TM. Baseline mean and heterogeneity of MR cartilage T2 are associated with morphologic degeneration of cartilage, meniscus, and bone marrow over 3 years--data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2012 Jul; 20(7):727-35.
Baum T, Müller D, Dobritz M, Wolf P, Rummeny EJ, Link TM, Bauer JS. Converted lumbar BMD values derived from sagittal reformations of contrast-enhanced MDCT predict incidental osteoporotic vertebral fractures. Calcif Tissue Int. 2012 Jun; 90(6):481-7.
Link TM. Osteoporosis imaging: state of the art and advanced imaging. Radiology. 2012 Apr; 263(1):3-17.
Alizai H, Nardo L, Karampinos DC, Joseph GB, Yap SP, Baum T, Krug R, Majumdar S, Link TM. Comparison of clinical semi-quantitative assessment of muscle fat infiltration with quantitative assessment using chemical shift-based water/fat separation in MR studies of the calf of post-menopausal women. Eur Radiol. 2012 Jul; 22(7):1592-600.
Souza RB, Baum T, Wu S, Feeley BT, Kadel N, Li X, Link TM, Majumdar S. Effects of unloading on knee articular cartilage T1rho and T2 magnetic resonance imaging relaxation times: a case series. J Orthop Sports Phys Ther. 2012 Jun; 42(6):511-20.
Hovis KK, Alizai H, Tham SC, Souza RB, Nevitt MC, McCulloch CE, Link TM. Non-traumatic anterior cruciate ligament abnormalities and their relationship to osteoarthritis using morphological grading and cartilage T2 relaxation times: data from the Osteoarthritis Initiative (OAI). Skeletal Radiol. 2012 Nov; 41(11):1435-43.
Lee T, Rammohan AV, Chan A, Tan VB, Das De S, Link TM, Eckstein F, Schafer BW. The susceptibility of the femoral neck to fracture: an assessment incorporating the effects of age-remodeling and stress reduction. J Biomech. 2012 Apr 05; 45(6):931-7.
Baum T, Joseph GB, Arulanandan A, Nardo L, Virayavanich W, Carballido-Gamio J, Nevitt MC, Lynch J, McCulloch CE, Link TM. Association of magnetic resonance imaging-based knee cartilage T2 measurements and focal knee lesions with knee pain: data from the Osteoarthritis Initiative. Arthritis Care Res (Hoboken). 2012 Feb; 64(2):248-55.
Zuo J, Joseph GB, Li X, Link TM, Hu SS, Berven SH, Kurhanewitz J, Majumdar S. In vivo intervertebral disc characterization using magnetic resonance spectroscopy and T1ρ imaging: association with discography and Oswestry Disability Index and Short Form-36 Health Survey. Spine (Phila Pa 1976). 2012 Feb 01; 37(3):214-21.
Koivumäki JE, Thevenot J, Pulkkinen P, Kuhn V, Link TM, Eckstein F, Jämsä T. Ct-based finite element models can be used to estimate experimentally measured failure loads in the proximal femur. Bone. 2012 Apr; 50(4):824-9.
Karampinos DC, Yu H, Shimakawa A, Link TM, Majumdar S. Chemical shift-based water/fat separation in the presence of susceptibility-induced fat resonance shift. Magn Reson Med. 2012 Nov; 68(5):1495-505.
Subburaj K, Souza RB, Stehling C, Wyman BT, Le Graverand-Gastineau MP, Link TM, Li X, Majumdar S. Association of MR relaxation and cartilage deformation in knee osteoarthritis. J Orthop Res. 2012 Jun; 30(6):919-26.
Prasad AP, George V, Porzig A, Horvai AE, Gross A, Shoback D, Link TM. Progressive craniofacial bone loss after cosmetic surgery at the forehead. Skeletal Radiol. 2012 Apr; 41(4):477-81.
Karampinos DC, Baum T, Nardo L, Alizai H, Yu H, Carballido-Gamio J, Yap SP, Shimakawa A, Link TM, Majumdar S. Characterization of the regional distribution of skeletal muscle adipose tissue in type 2 diabetes using chemical shift-based water/fat separation. J Magn Reson Imaging. 2012 Apr; 35(4):899-907.
Link TM. Screening: Assessing bone structure in the prediction of osteoporotic fractures. Nat Rev Rheumatol. 2011 Nov 15; 8(1):6-8.
Karampinos DC, Banerjee S, King KF, Link TM, Majumdar S. Considerations in high-resolution skeletal muscle diffusion tensor imaging using single-shot echo planar imaging with stimulated-echo preparation and sensitivity encoding. NMR Biomed. 2012 May; 25(5):766-78.
Pialat JB, Burghardt AJ, Sode M, Link TM, Majumdar S. Visual grading of motion induced image degradation in high resolution peripheral computed tomography: impact of image quality on measures of bone density and micro-architecture. Bone. 2012 Jan; 50(1):111-8.
Baum T, Stehling C, Joseph GB, Carballido-Gamio J, Schwaiger BJ, Müller-Höcker C, Nevitt MC, Lynch J, McCulloch CE, Link TM. Changes in knee cartilage T2 values over 24 months in subjects with and without risk factors for knee osteoarthritis and their association with focal knee lesions at baseline: data from the osteoarthritis initiative. J Magn Reson Imaging. 2012 Feb; 35(2):370-8.
Li X, Yu A, Virayavanich W, Noworolski SM, Link TM, Imboden J. Quantitative characterization of bone marrow edema pattern in rheumatoid arthritis using 3 Tesla MRI. J Magn Reson Imaging. 2012 Jan; 35(1):211-7.
Majumdar S, Link TM, Steinbach LS, Hu S, Kurhanewicz J. Diagnostic tools and imaging methods in intervertebral disk degeneration. Orthop Clin North Am. 2011 Oct; 42(4):501-11, viii.
Shin CS, Souza RB, Kumar D, Link TM, Wyman BT, Majumdar S. In vivo tibiofemoral cartilage-to-cartilage contact area of females with medial osteoarthritis under acute loading using MRI. J Magn Reson Imaging. 2011 Dec; 34(6):1405-13.
Joseph GB, Baum T, Carballido-Gamio J, Nardo L, Virayavanich W, Alizai H, Lynch JA, McCulloch CE, Majumdar S, Link TM. Texture analysis of cartilage T2 maps: individuals with risk factors for OA have higher and more heterogeneous knee cartilage MR T2 compared to normal controls--data from the osteoarthritis initiative. Arthritis Res Ther. 2011; 13(5):R153.
Pan J, Pialat JB, Joseph T, Kuo D, Joseph GB, Nevitt MC, Link TM. Knee cartilage T2 characteristics and evolution in relation to morphologic abnormalities detected at 3-T MR imaging: a longitudinal study of the normal control cohort from the Osteoarthritis Initiative. Radiology. 2011 Nov; 261(2):507-15.
Laberge MA, Baum T, Virayavanich W, Nardo L, Nevitt MC, Lynch J, McCulloch CE, Link TM. Obesity increases the prevalence and severity of focal knee abnormalities diagnosed using 3T MRI in middle-aged subjects--data from the Osteoarthritis Initiative. Skeletal Radiol. 2012 Jun; 41(6):633-41.
Baum T, Yap SP, Karampinos DC, Nardo L, Kuo D, Burghardt AJ, Masharani UB, Schwartz AV, Li X, Link TM. Does vertebral bone marrow fat content correlate with abdominal adipose tissue, lumbar spine bone mineral density, and blood biomarkers in women with type 2 diabetes mellitus? J Magn Reson Imaging. 2012 Jan; 35(1):117-24.
Burghardt AJ, Link TM, Majumdar S. High-resolution computed tomography for clinical imaging of bone microarchitecture. Clin Orthop Relat Res. 2011 Aug; 469(8):2179-93.
Hovis KK, Stehling C, Souza RB, Haughom BD, Baum T, Nevitt M, McCulloch C, Lynch JA, Link TM. Physical activity is associated with magnetic resonance imaging-based knee cartilage T2 measurements in asymptomatic subjects with and those without osteoarthritis risk factors. Arthritis Rheum. 2011 Aug; 63(8):2248-56.
Krug R, Larson PE, Wang C, Burghardt AJ, Kelley DA, Link TM, Zhang X, Vigneron DB, Majumdar S. Ultrashort echo time MRI of cortical bone at 7 tesla field strength: a feasibility study. J Magn Reson Imaging. 2011 Sep; 34(3):691-5.
Mills PH, Hitchens TK, Foley LM, Link T, Ye Q, Weiss CR, Thompson JD, Gilson WD, Arepally A, Melick JA, Kochanek PM, Ho C, Bulte JW, Ahrens ET. Automated detection and characterization of SPIO-labeled cells and capsules using magnetic field perturbations. Magn Reson Med. 2012 Jan; 67(1):278-89.
Link TM, Li X. Bone marrow changes in osteoarthritis. Semin Musculoskelet Radiol. 2011 Jul; 15(3):238-46.
Jobke B, Muche B, Burghardt AJ, Semler J, Link TM, Majumdar S. Teriparatide in bisphosphonate-resistant osteoporosis: microarchitectural changes and clinical results after 6 and 18 months. Calcif Tissue Int. 2011 Aug; 89(2):130-9.
Virayavanich W, Ringler MD, Chin CT, Baum T, Giaconi JC, O'Donnell RJ, Horvai AE, Jones KD, Link TM. CT-guided biopsy of bone and soft-tissue lesions: role of on-site immediate cytologic evaluation. J Vasc Interv Radiol. 2011 Jul; 22(7):1024-30.
Stehling C, Baum T, Mueller-Hoecker C, Liebl H, Carballido-Gamio J, Joseph GB, Majumdar S, Link TM. A novel fast knee cartilage segmentation technique for T2 measurements at MR imaging--data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2011 Aug; 19(8):984-9.
Stahl R, Jain SK, Lutz J, Wyman BT, Le Graverand-Gastineau MP, Vignon E, Majumdar S, Link TM. Osteoarthritis of the knee at 3.0 T: comparison of a quantitative and a semi-quantitative score for the assessment of the extent of cartilage lesion and bone marrow edema pattern in a 24-month longitudinal study. Skeletal Radiol. 2011 Oct; 40(10):1315-27.
Giaconi JC, Link TM, Vail TP, Fisher Z, Hong R, Singh R, Steinbach LS. Morbidity of direct MR arthrography. AJR Am J Roentgenol. 2011 Apr; 196(4):868-74.
Li X, Kuo D, Schafer AL, Porzig A, Link TM, Black D, Schwartz AV. Quantification of vertebral bone marrow fat content using 3 Tesla MR spectroscopy: reproducibility, vertebral variation, and applications in osteoporosis. J Magn Reson Imaging. 2011 Apr; 33(4):974-9.
Cotofana S, Eckstein F, Wirth W, Souza RB, Li X, Wyman B, Hellio-Le Graverand MP, Link T, Majumdar S. In vivo measures of cartilage deformation: patterns in healthy and osteoarthritic female knees using 3T MR imaging. Eur Radiol. 2011 Jun; 21(6):1127-35.
Karampinos DC, Yu H, Shimakawa A, Link TM, Majumdar S. T₁-corrected fat quantification using chemical shift-based water/fat separation: application to skeletal muscle. Magn Reson Med. 2011 Nov; 66(5):1312-26.
Carballido-Gamio J, Folkesson J, Karampinos DC, Baum T, Link TM, Majumdar S, Krug R. Generation of an atlas of the proximal femur and its application to trabecular bone analysis. Magn Reson Med. 2011 Oct; 66(4):1181-91.
Sode M, Burghardt AJ, Pialat JB, Link TM, Majumdar S. Quantitative characterization of subject motion in HR-pQCT images of the distal radius and tibia. Bone. 2011 Jun 01; 48(6):1291-7.
Cheung S, Dillon E, Tham SC, Feeley BT, Link TM, Steinbach L, Ma CB. The presence of fatty infiltration in the infraspinatus: its relation with the condition of the supraspinatus tendon. Arthroscopy. 2011 Apr; 27(4):463-70.
Issever AS, Link TM. [Radiological diagnosis of osteoporosis]. Z Rheumatol. 2011 Feb; 70(2):135-44, quiz 145.
Tham SC, Horvai AE, Link T, Steinbach L. Soft tissue mass at the infrascapular fossa. Skeletal Radiol. 2011 Jan; 40(1):105-6, 123-4.
Li X, Kuo D, Theologis A, Carballido-Gamio J, Stehling C, Link TM, Ma CB, Majumdar S. Cartilage in anterior cruciate ligament-reconstructed knees: MR imaging T1{rho} and T2--initial experience with 1-year follow-up. Radiology. 2011 Feb; 258(2):505-14.
Li X, Cheng J, Lin K, Saadat E, Bolbos RI, Jobke B, Ries MD, Horvai A, Link TM, Majumdar S. Quantitative MRI using T1ρ and T2 in human osteoarthritic cartilage specimens: correlation with biochemical measurements and histology. Magn Reson Imaging. 2011 Apr; 29(3):324-34.
Carballido-Gamio J, Joseph GB, Lynch JA, Link TM, Majumdar S. Longitudinal analysis of MRI T2 knee cartilage laminar organization in a subset of patients from the osteoarthritis initiative: a texture approach. Magn Reson Med. 2011 Apr; 65(4):1184-94.
Kazakia GJ, Burghardt AJ, Link TM, Majumdar S. Variations in morphological and biomechanical indices at the distal radius in subjects with identical BMD. J Biomech. 2011 Jan 11; 44(2):257-66.
Folkesson J, Goldenstein J, Carballido-Gamio J, Kazakia G, Burghardt AJ, Rodriguez A, Krug R, de Papp AE, Link TM, Majumdar S. Longitudinal evaluation of the effects of alendronate on MRI bone microarchitecture in postmenopausal osteopenic women. Bone. 2011 Mar 01; 48(3):611-21.
Rodríguez-Soto AE, Fritscher KD, Schuler B, Issever AS, Roth T, Kamelger F, Kammerlander C, Blauth M, Schubert R, Link TM. Texture analysis, bone mineral density, and cortical thickness of the proximal femur: fracture risk prediction. J Comput Assist Tomogr. 2010 Nov-Dec; 34(6):949-57.
Pan J, Stehling C, Muller-Hocker C, Schwaiger BJ, Lynch J, McCulloch CE, Nevitt MC, Link TM. Vastus lateralis/vastus medialis cross-sectional area ratio impacts presence and degree of knee joint abnormalities and cartilage T2 determined with 3T MRI - an analysis from the incidence cohort of the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2011 Jan; 19(1):65-73.
Stehling C, Luke A, Stahl R, Baum T, Joseph G, Pan J, Link TM. Meniscal T1rho and T2 measured with 3.0T MRI increases directly after running a marathon. Skeletal Radiol. 2011 Jun; 40(6):725-35.
Souza RB, Stehling C, Wyman BT, Hellio Le Graverand MP, Li X, Link TM, Majumdar S. The effects of acute loading on T1rho and T2 relaxation times of tibiofemoral articular cartilage. Osteoarthritis Cartilage. 2010 Dec; 18(12):1557-63.
Diederichs G, Engelken F, Marshall LM, Peters K, Black DM, Issever AS, Barrett-Connor E, Orwoll E, Hamm B, Link TM, Osteoporotic Fractures in Men Research Group. Diffuse idiopathic skeletal hyperostosis (DISH): relation to vertebral fractures and bone density. Osteoporos Int. 2011 Jun; 22(6):1789-97.
Baum T, Müller D, Dobritz M, Rummeny EJ, Link TM, Bauer JS. BMD measurements of the spine derived from sagittal reformations of contrast-enhanced MDCT without dedicated software. Eur J Radiol. 2011 Nov; 80(2):e140-5.
Burghardt AJ, Issever AS, Schwartz AV, Davis KA, Masharani U, Majumdar S, Link TM. High-resolution peripheral quantitative computed tomographic imaging of cortical and trabecular bone microarchitecture in patients with type 2 diabetes mellitus. J Clin Endocrinol Metab. 2010 Nov; 95(11):5045-55.
Virayavanich W, Singh R, O'Donnell RJ, Horvai AE, Goldsby RE, Link TM. Osteoid osteoma of the femur in a 7-month-old infant treated with radiofrequency ablation. Skeletal Radiol. 2010 Nov; 39(11):1145-9.
Zarins ZA, Bolbos RI, Pialat JB, Link TM, Li X, Souza RB, Majumdar S. Cartilage and meniscus assessment using T1rho and T2 measurements in healthy subjects and patients with osteoarthritis. Osteoarthritis Cartilage. 2010 Nov; 18(11):1408-16.
Issever AS, Link TM, Newitt D, Munoz T, Majumdar S. Interrelationships between 3-T-MRI-derived cortical and trabecular bone structure parameters and quantitative-computed-tomography-derivedbone mineral density. Magn Reson Imaging. 2010 Nov; 28(9):1299-305.
Luke AC, Stehling C, Stahl R, Li X, Kay T, Takamoto S, Ma B, Majumdar S, Link T. High-field magnetic resonance imaging assessment of articular cartilage before and after marathon running: does long-distance running lead to cartilage damage? Am J Sports Med. 2010 Nov; 38(11):2273-80.
Link TM. The Founder's Lecture 2009: advances in imaging of osteoporosis and osteoarthritis. Skeletal Radiol. 2010 Oct; 39(10):943-55.
Burghardt AJ, Kazakia GJ, Sode M, de Papp AE, Link TM, Majumdar S. A longitudinal HR-pQCT study of alendronate treatment in postmenopausal women with low bone density: Relations among density, cortical and trabecular microarchitecture, biomechanics, and bone turnover. J Bone Miner Res. 2010 Dec; 25(12):2558-71.
Damilakis J, Adams JE, Guglielmi G, Link TM. Radiation exposure in X-ray-based imaging techniques used in osteoporosis. Eur Radiol. 2010 Nov; 20(11):2707-14.
Schuler B, Fritscher KD, Kuhn V, Eckstein F, Link TM, Schubert R. Assessment of the individual fracture risk of the proximal femur by using statistical appearance models. Med Phys. 2010 Jun; 37(6):2560-71.
Koivumäki JE, Thevenot J, Pulkkinen P, Salmi JA, Kuhn V, Lochmüller EM, Link TM, Eckstein F, Jämsä T. Does femoral strain distribution coincide with the occurrence of cervical versus trochanteric hip fractures? An experimental finite element study. Med Biol Eng Comput. 2010 Jul; 48(7):711-7.
Wirth W, Frobell RB, Souza RB, Li X, Wyman BT, Le Graverand MP, Link TM, Majumdar S, Eckstein F. A three-dimensional quantitative method to measure meniscus shape, position, and signal intensity using MR images: a pilot study and preliminary results in knee osteoarthritis. Magn Reson Med. 2010 May; 63(5):1162-71.
Burghardt AJ, Kazakia GJ, Ramachandran S, Link TM, Majumdar S. Age- and gender-related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibia. J Bone Miner Res. 2010 May; 25(5):983-93.
Krug R, Burghardt AJ, Majumdar S, Link TM. High-resolution imaging techniques for the assessment of osteoporosis. Radiol Clin North Am. 2010 May; 48(3):601-21.
Blumenkrantz G, Zuo J, Li X, Kornak J, Link TM, Majumdar S. In vivo 3.0-tesla magnetic resonance T1rho and T2 relaxation mapping in subjects with intervertebral disc degeneration and clinical symptoms. Magn Reson Med. 2010 May; 63(5):1193-200.
Issever AS, Link TM. [Radiological diagnosis of osteoporosis]. Radiologe. 2010 May; 50(5):471-81.
Tham SC, Horvai AE, Link T, Steinbach L. Soft tissue mass at the infrascapular fossa. Skeletal Radiol. 2010 Apr 15.
Tham SC, Horvai AE, Link T, Steinbach L. Soft tissue mass at the infrascapular fossa. Skeletal Radiol. 2010 Apr 14.
Ristow O, Stehling C, Krug R, Steinbach L, Sabo G, Ambekar A, Huber M, Link TM. Isotropic 3-dimensional fast spin echo imaging versus standard 2-dimensional imaging at 3.0 T of the knee: artificial cartilage and meniscal lesions in a porcine model. J Comput Assist Tomogr. 2010 Mar-Apr; 34(2):260-9.
Zhao J, Li X, Bolbos RI, Link TM, Majumdar S. Longitudinal assessment of bone marrow edema-like lesions and cartilage degeneration in osteoarthritis using 3 T MR T1rho quantification. Skeletal Radiol. 2010 Jun; 39(6):523-31.
Sode M, Burghardt AJ, Kazakia GJ, Link TM, Majumdar S. Regional variations of gender-specific and age-related differences in trabecular bone structure of the distal radius and tibia. Bone. 2010 Jun; 46(6):1652-60.
Stehling C, Lane NE, Nevitt MC, Lynch J, McCulloch CE, Link TM. Subjects with higher physical activity levels have more severe focal knee lesions diagnosed with 3T MRI: analysis of a non-symptomatic cohort of the osteoarthritis initiative. Osteoarthritis Cartilage. 2010 Jun; 18(6):776-86.
Carballido-Gamio J, Blumenkrantz G, Lynch JA, Link TM, Majumdar S. Longitudinal analysis of MRI T(2) knee cartilage laminar organization in a subset of patients from the osteoarthritis initiative. Magn Reson Med. 2010 Feb; 63(2):465-72.
Link TM. MR imaging in osteoarthritis: hardware, coils, and sequences. Magn Reson Imaging Clin N Am. 2010 Feb; 18(1):95-110.
Le Graverand MP, Buck RJ, Wyman BT, Vignon E, Mazzuca SA, Brandt KD, Piperno M, Charles HC, Hudelmaier M, Hunter DJ, Jackson C, Kraus VB, Link TM, Majumdar S, Prasad PV, Schnitzer TJ, Vaz A, Wirth W, Eckstein F. Change in regional cartilage morphology and joint space width in osteoarthritis participants versus healthy controls: a multicentre study using 3.0 Tesla MRI and Lyon-Schuss radiography. Ann Rheum Dis. 2010 Jan; 69(1):155-62.
Folkesson J, Carballido-Gamio J, Eckstein F, Link TM, Majumdar S. Local bone enhancement fuzzy clustering for segmentation of MR trabecular bone images. Med Phys. 2010 Jan; 37(1):295-302.
Stehling C, Liebl H, Krug R, Lane NE, Nevitt MC, Lynch J, McCulloch CE, Link TM. Patellar cartilage: T2 values and morphologic abnormalities at 3.0-T MR imaging in relation to physical activity in asymptomatic subjects from the osteoarthritis initiative. Radiology. 2010 Feb; 254(2):509-20.
Zuo J, Saadat E, Romero A, Loo K, Li X, Link TM, Kurhanewicz J, Majumdar S. Assessment of intervertebral disc degeneration with magnetic resonance single-voxel spectroscopy. Magn Reson Med. 2009 Nov; 62(5):1140-6.
Huber MB, Carballido-Gamio J, Fritscher K, Schubert R, Haenni M, Hengg C, Majumdar S, Link TM. Development and testing of texture discriminators for the analysis of trabecular bone in proximal femur radiographs. Med Phys. 2009 Nov; 36(11):5089-98.
Baum T, Carballido-Gamio J, Huber MB, Müller D, Monetti R, Räth C, Eckstein F, Lochmüller EM, Majumdar S, Rummeny EJ, Link TM, Bauer JS. Automated 3D trabecular bone structure analysis of the proximal femur--prediction of biomechanical strength by CT and DXA. Osteoporos Int. 2010 Sep; 21(9):1553-64.
Krug R, Stehling C, Kelley DA, Majumdar S, Link TM. Imaging of the musculoskeletal system in vivo using ultra-high field magnetic resonance at 7 T. Invest Radiol. 2009 Sep; 44(9):613-8.
Carballido-Gamio J, Stahl R, Blumenkrantz G, Romero A, Majumdar S, Link TM. Spatial analysis of magnetic resonance T1rho and T2 relaxation times improves classification between subjects with and without osteoarthritis. Med Phys. 2009 Sep; 36(9):4059-67.
Issever AS, Link TM, Kentenich M, Rogalla P, Schwieger K, Huber MB, Burghardt AJ, Majumdar S, Diederichs G. Trabecular bone structure analysis in the osteoporotic spine using a clinical in vivo setup for 64-slice MDCT imaging: comparison to microCT imaging and microFE modeling. J Bone Miner Res. 2009 Sep; 24(9):1628-37.
Issever AS, Link TM, Kentenich M, Rogalla P, Burghardt AJ, Kazakia GJ, Majumdar S, Diederichs G. Assessment of trabecular bone structure using MDCT: comparison of 64- and 320-slice CT using HR-pQCT as the reference standard. Eur Radiol. 2010 Feb; 20(2):458-68.
Link TM, Adams JE. The radiologist's important roles and responsibilities in osteoporosis. Eur J Radiol. 2009 Sep; 71(3):385-7.
Bauer JS, Link TM. Advances in osteoporosis imaging. Eur J Radiol. 2009 Sep; 71(3):440-9.
Link TM. MR imaging in osteoarthritis: hardware, coils, and sequences. Radiol Clin North Am. 2009 Jul; 47(4):617-32.
Li X, Pai A, Blumenkrantz G, Carballido-Gamio J, Link T, Ma B, Ries M, Majumdar S. Spatial distribution and relationship of T1rho and T2 relaxation times in knee cartilage with osteoarthritis. Magn Reson Med. 2009 Jun; 61(6):1310-8.
Daldrup-Link HE, Mohanty A, Cuenod C, Pichler B, Link T. New perspectives on bone marrow contrast agents and molecular imaging. Semin Musculoskelet Radiol. 2009 Jun; 13(2):145-56.
Wong S, Steinbach L, Zhao J, Stehling C, Ma CB, Link TM. Comparative study of imaging at 3.0 T versus 1.5 T of the knee. Skeletal Radiol. 2009 Aug; 38(8):761-9.
Folkesson J, Krug R, Goldenstein J, Issever AS, Fang C, Link TM, Majumdar S. Evaluation of correction methods for coil-induced intensity inhomogeneities and their influence on trabecular bone structure parameters from MR images. Med Phys. 2009 Apr; 36(4):1267-74.
Zhao J, Krug R, Xu D, Lu Y, Link TM. MRI of the spine: image quality and normal-neoplastic bone marrow contrast at 3 T versus 1.5 T. AJR Am J Roentgenol. 2009 Apr; 192(4):873-80.
Burghardt AJ, Kazakia GJ, Link TM, Majumdar S. Automated simulation of areal bone mineral density assessment in the distal radius from high-resolution peripheral quantitative computed tomography. Osteoporos Int. 2009 Dec; 20(12):2017-24.
Hellio Le Graverand MP, Buck RJ, Wyman BT, Vignon E, Mazzuca SA, Brandt KD, Piperno M, Charles HC, Hudelmaier M, Hunter DJ, Jackson C, Kraus VB, Link TM, Majumdar S, Prasad PV, Schnitzer TJ, Vaz A, Wirth W, Eckstein F. Subregional femorotibial cartilage morphology in women--comparison between healthy controls and participants with different grades of radiographic knee osteoarthritis. Osteoarthritis Cartilage. 2009 Sep; 17(9):1177-85.
Stahl R, Krug R, Kelley DA, Zuo J, Ma CB, Majumdar S, Link TM. Assessment of cartilage-dedicated sequences at ultra-high-field MRI: comparison of imaging performance and diagnostic confidence between 3.0 and 7.0 T with respect to osteoarthritis-induced changes at the knee joint. Skeletal Radiol. 2009 Aug; 38(8):771-83.
Guglielmi G, Adams J, Link TM. Quantitative ultrasound in the assessment of skeletal status. Eur Radiol. 2009 Aug; 19(8):1837-48.
Link TM. Correlations between joint morphology and pain and between magnetic resonance imaging, histology, and micro-computed tomography. J Bone Joint Surg Am. 2009 Feb; 91 Suppl 1:30-2.
Carballido-Gamio J, Krug R, Huber MB, Hyun B, Eckstein F, Majumdar S, Link TM. Geodesic topological analysis of trabecular bone microarchitecture from high-spatial resolution magnetic resonance images. Magn Reson Med. 2009 Feb; 61(2):448-56.
Zhao J, Link TM. MRI in degenerative arthritides: structural and clinical aspects. Ann N Y Acad Sci. 2009 Feb; 1154:115-35.
Diederichs G, Link TM, Kentenich M, Schwieger K, Huber MB, Burghardt AJ, Majumdar S, Rogalla P, Issever AS. Assessment of trabecular bone structure of the calcaneus using multi-detector CT: correlation with microCT and biomechanical testing. Bone. 2009 May; 44(5):976-83.
Ristow O, Steinbach L, Sabo G, Krug R, Huber M, Rauscher I, Ma B, Link TM. Isotropic 3D fast spin-echo imaging versus standard 2D imaging at 3.0 T of the knee--image quality and diagnostic performance. Eur Radiol. 2009 May; 19(5):1263-72.
Bauer JS, Monetti R, Krug R, Matsuura M, Mueller D, Eckstein F, Rummeny EJ, Lochmueller EM, Raeth CW, Link TM. Advances of 3T MR imaging in visualizing trabecular bone structure of the calcaneus are partially SNR-independent: analysis using simulated noise in relation to micro-CT, 1.5T MRI, and biomechanical strength. J Magn Reson Imaging. 2009 Jan; 29(1):132-40.
Lochmüller EM, Matsuura M, Bauer J, Hitzl W, Link TM, Müller R, Eckstein F. Site-specific deterioration of trabecular bone architecture in men and women with advancing age. J Bone Miner Res. 2008 Dec; 23(12):1964-73.
Diederichs G, Seim H, Meyer H, Issever AS, Link TM, Schröder RJ, Scheibel M. CT-based patient-specific modeling of glenoid rim defects: a feasibility study. AJR Am J Roentgenol. 2008 Nov; 191(5):1406-11.
Bolbos RI, Ma CB, Link TM, Majumdar S, Li X. In vivo T1rho quantitative assessment of knee cartilage after anterior cruciate ligament injury using 3 Tesla magnetic resonance imaging. Invest Radiol. 2008 Nov; 43(11):782-8.
Rauscher I, Stahl R, Cheng J, Li X, Huber MB, Luke A, Majumdar S, Link TM. Meniscal measurements of T1rho and T2 at MR imaging in healthy subjects and patients with osteoarthritis. Radiology. 2008 Nov; 249(2):591-600.
Diederichs G, Link T, Marie K, Huber M, Rogalla P, Burghardt A, Majumdar S, Issever A. Feasibility of measuring trabecular bone structure of the proximal femur using 64-slice multidetector computed tomography in a clinical setting. Calcif Tissue Int. 2008 Nov; 83(5):332-41.
Lochmüller EM, Kristin J, Matsuura M, Kuhn V, Hudelmaier M, Link TM, Eckstein F. Measurement of trabecular bone microstructure does not improve prediction of mechanical failure loads at the distal radius compared with bone mass alone. Calcif Tissue Int. 2008 Oct; 83(4):293-9.
Gündüz K, Pulido JS, Pulido JE, Link T. Correlation of fundus autofluorescence with fluorescein and indocyanine green angiography in choroidal melanocytic lesions. Retina. 2008 Oct; 28(9):1257-64.
Collet LC, Pulido JS, Gündüz K, Diago T, McCannel C, Blodi C, Link T. Fundus autofluorescence in choroidal metastatic lesions: a pilot study. Retina. 2008 Oct; 28(9):1251-6.
Cabarrus MC, Ambekar A, Lu Y, Link TM. MRI and CT of insufficiency fractures of the pelvis and the proximal femur. AJR Am J Roentgenol. 2008 Oct; 191(4):995-1001.
Blumenfeld J, Studholme C, Carballido-Gamio J, Carpenter D, Link TM, Majumdar S. Three-dimensional image registration of MR proximal femur images for the analysis of trabecular bone parameters. Med Phys. 2008 Oct; 35(10):4630-9.
Link TM. In vivo quantification of cortical bone water with ultrashort echo-time MR imaging: a new parameter to measure bone quality? Radiology. 2008 Sep; 248(3):705-6.
Bauer JS, Barr C, Henning TD, Malfair D, Ma CB, Steinbach L, Link TM. Magnetic resonance imaging of the ankle at 3.0 Tesla and 1.5 Tesla in human cadaver specimens with artificially created lesions of cartilage and ligaments. Invest Radiol. 2008 Sep; 43(9):604-11.
Stahl R, Luke A, Li X, Carballido-Gamio J, Ma CB, Majumdar S, Link TM. T1rho, T2 and focal knee cartilage abnormalities in physically active and sedentary healthy subjects versus early OA patients--a 3.0-Tesla MRI study. Eur Radiol. 2009 Jan; 19(1):132-43.
Li X, Ma BC, Bolbos RI, Stahl R, Lozano J, Zuo J, Lin K, Link TM, Safran M, Majumdar S. Quantitative assessment of bone marrow edema-like lesion and overlying cartilage in knees with osteoarthritis and anterior cruciate ligament tear using MR imaging and spectroscopic imaging at 3 Tesla. J Magn Reson Imaging. 2008 Aug; 28(2):453-61.
Bolbos RI, Link TM, Ma CB, Majumdar S, Li X. T1rho relaxation time of the meniscus and its relationship with T1rho of adjacent cartilage in knees with acute ACL injuries at 3 T. Osteoarthritis Cartilage. 2009 Jan; 17(1):12-8.
Carballido-Gamio J, Link TM, Li X, Han ET, Krug R, Ries MD, Majumdar S. Feasibility and reproducibility of relaxometry, morphometric, and geometrical measurements of the hip joint with magnetic resonance imaging at 3T. J Magn Reson Imaging. 2008 Jul; 28(1):227-35.
Mazzuca SA, Hellio Le Graverand MP, Vignon E, Hunter DJ, Jackson CG, Kraus VB, Link TM, Schnitzer TJ, Vaz A, Charles HC. Performance of a non-fluoroscopically assisted substitute for the Lyon schuss knee radiograph: quality and reproducibility of positioning and sensitivity to joint space narrowing in osteoarthritic knees. Osteoarthritis Cartilage. 2008 Dec; 16(12):1555-9.
Carballido-Gamio J, Link TM, Majumdar S. New techniques for cartilage magnetic resonance imaging relaxation time analysis: texture analysis of flattened cartilage and localized intra- and inter-subject comparisons. Magn Reson Med. 2008 Jun; 59(6):1472-7.
Saadat E, Jobke B, Chu B, Lu Y, Cheng J, Li X, Ries MD, Majumdar S, Link TM. Diagnostic performance of in vivo 3-T MRI for articular cartilage abnormalities in human osteoarthritic knees using histology as standard of reference. Eur Radiol. 2008 Oct; 18(10):2292-302.
Stahl R, Luke A, Ma CB, Krug R, Steinbach L, Majumdar S, Link TM. Prevalence of pathologic findings in asymptomatic knees of marathon runners before and after a competition in comparison with physically active subjects-a 3.0 T magnetic resonance imaging study. Skeletal Radiol. 2008 Jul; 37(7):627-38.
Huber MB, Carballido-Gamio J, Bauer JS, Baum T, Eckstein F, Lochmüller EM, Majumdar S, Link TM. Proximal femur specimens: automated 3D trabecular bone mineral density analysis at multidetector CT--correlation with biomechanical strength measurement. Radiology. 2008 May; 247(2):472-81.
Müller D, Bauer JS, Zeile M, Rummeny EJ, Link TM. Significance of sagittal reformations in routine thoracic and abdominal multislice CT studies for detecting osteoporotic fractures and other spine abnormalities. Eur Radiol. 2008 Aug; 18(8):1696-702.
Bolbos RI, Zuo J, Banerjee S, Link TM, Ma CB, Li X, Majumdar S. Relationship between trabecular bone structure and articular cartilage morphology and relaxation times in early OA of the knee joint using parallel MRI at 3 T. Osteoarthritis Cartilage. 2008 Oct; 16(10):1150-9.
Kazakia GJ, Hyun B, Burghardt AJ, Krug R, Newitt DC, de Papp AE, Link TM, Majumdar S. In vivo determination of bone structure in postmenopausal women: a comparison of HR-pQCT and high-field MR imaging. J Bone Miner Res. 2008 Apr; 23(4):463-74.
Krug R, Carballido-Gamio J, Banerjee S, Burghardt AJ, Link TM, Majumdar S. In vivo ultra-high-field magnetic resonance imaging of trabecular bone microarchitecture at 7 T. J Magn Reson Imaging. 2008 Apr; 27(4):854-9.
Guglielmi G, Diacinti D, van Kuijk C, Aparisi F, Krestan C, Adams JE, Link TM. Vertebral morphometry: current methods and recent advances. Eur Radiol. 2008 Jul; 18(7):1484-96.
Blumenkrantz G, Stahl R, Carballido-Gamio J, Zhao S, Lu Y, Munoz T, Hellio Le Graverand-Gastineau MP, Jain SK, Link TM, Majumdar S. The feasibility of characterizing the spatial distribution of cartilage T(2) using texture analysis. Osteoarthritis Cartilage. 2008 May; 16(5):584-90.
Eckstein F, Buck RJ, Burstein D, Charles HC, Crim J, Hudelmaier M, Hunter DJ, Hutchins G, Jackson C, Kraus VB, Lane NE, Link TM, Majumdar LS, Mazzuca S, Prasad PV, Schnitzer TJ, Taljanovic MS, Vaz A, Wyman B, Le Graverand MP, A9001140 Study Group. Precision of 3.0 Tesla quantitative magnetic resonance imaging of cartilage morphology in a multicentre clinical trial. Ann Rheum Dis. 2008 Dec; 67(12):1683-8.
Le Graverand MP, Vignon EP, Brandt KD, Mazzuca SA, Piperno M, Buck R, Charles HC, Hunter DJ, Jackson CG, Kraus VB, Link TM, Schnitzer TJ, Vaz A, Wyman B. Head-to-head comparison of the Lyon Schuss and fixed flexion radiographic techniques. Long-term reproducibility in normal knees and sensitivity to change in osteoarthritic knees. Ann Rheum Dis. 2008 Nov; 67(11):1562-6.
Keshari KR, Lotz JC, Link TM, Hu S, Majumdar S, Kurhanewicz J. Lactic acid and proteoglycans as metabolic markers for discogenic back pain. Spine (Phila Pa 1976). 2008 Feb 01; 33(3):312-7.
Fritscher K, Schuler B, Link T, Eckstein F, Suhm N, Hänni M, Hengg C, Schubert R. Prediction of biomechanical parameters of the proximal femur using statistical appearance models and support vector regression. Med Image Comput Comput Assist Interv. 2008; 11(Pt 1):568-75.
Krug R, Carballido-Gamio J, Banerjee S, Stahl R, Carvajal L, Xu D, Vigneron D, Kelley DA, Link TM, Majumdar S. In vivo bone and cartilage MRI using fully-balanced steady-state free-precession at 7 tesla. Magn Reson Med. 2007 Dec; 58(6):1294-8.
Krug R, Carballido-Gamio J, Burghardt AJ, Kazakia G, Hyun BH, Jobke B, Banerjee S, Huber M, Link TM, Majumdar S. Assessment of trabecular bone structure comparing magnetic resonance imaging at 3 Tesla with high-resolution peripheral quantitative computed tomography ex vivo and in vivo. Osteoporos Int. 2008 May; 19(5):653-61.
Davis KA, Burghardt AJ, Link TM, Majumdar S. The effects of geometric and threshold definitions on cortical bone metrics assessed by in vivo high-resolution peripheral quantitative computed tomography. Calcif Tissue Int. 2007 Nov; 81(5):364-71.
Amselem L, Pulido JS, Gunduz K, Bakri SJ, Diaz-Llopis M, Dolan JW, Morgan K, De Souza S, Link T, Rosvold J. Changes in fundus autofluorescence of choroidal melanomas following treatment. Eye (Lond). 2009 Feb; 23(2):428-34.
Lochmüller EM, Pöschl K, Würstlin L, Matsuura M, Müller R, Link TM, Eckstein F. Does thoracic or lumbar spine bone architecture predict vertebral failure strength more accurately than density? Osteoporos Int. 2008 Apr; 19(4):537-45.
Carballido-Gamio J, Bauer JS, Stahl R, Lee KY, Krause S, Link TM, Majumdar S. Inter-subject comparison of MRI knee cartilage thickness. Med Image Anal. 2008 Apr; 12(2):120-35.
Patel PV, Eckstein F, Carballido-Gamio J, Phan C, Matsuura M, Lochmüller EM, Majumdar S, Link TM. Fuzzy logic structure analysis of trabecular bone of the calcaneus to estimate proximal femur fracture load and discriminate subjects with and without vertebral fractures using high-resolution magnetic resonance imaging at 1.5 T and 3 T. Calcif Tissue Int. 2007 Oct; 81(4):294-304.
Link TM, de Mayo R, O'Donnell RJ. Radiofrequency ablation-an alternative for definitive treatment of solitary bone metastases. Eur Radiol. 2007 Nov; 17(11):3012-3.
Bauer JS, Banerjee S, Henning TD, Krug R, Majumdar S, Link TM. Fast high-spatial-resolution MRI of the ankle with parallel imaging using GRAPPA at 3 T. AJR Am J Roentgenol. 2007 Jul; 189(1):240-5.
Stahl R, Blumenkrantz G, Carballido-Gamio J, Zhao S, Munoz T, Hellio Le Graverand-Gastineau MP, Li X, Majumdar S, Link TM. MRI-derived T2 relaxation times and cartilage morphometry of the tibio-femoral joint in subjects with and without osteoarthritis during a 1-year follow-up. Osteoarthritis Cartilage. 2007 Nov; 15(11):1225-34.
Eckstein F, Matsuura M, Kuhn V, Priemel M, Müller R, Link TM, Lochmüller EM. Sex differences of human trabecular bone microstructure in aging are site-dependent. J Bone Miner Res. 2007 Jun; 22(6):817-24.
Bauer JS, Link TM, Burghardt A, Henning TD, Mueller D, Majumdar S, Prevrhal S. Analysis of trabecular bone structure with multidetector spiral computed tomography in a simulated soft-tissue environment. Calcif Tissue Int. 2007 Jun; 80(6):366-73.
Bauer JS, Henning TD, Müeller D, Lu Y, Majumdar S, Link TM. Volumetric quantitative CT of the spine and hip derived from contrast-enhanced MDCT: conversion factors. AJR Am J Roentgenol. 2007 May; 188(5):1294-301.
Li X, Benjamin Ma C, Link TM, Castillo DD, Blumenkrantz G, Lozano J, Carballido-Gamio J, Ries M, Majumdar S. In vivo T(1rho) and T(2) mapping of articular cartilage in osteoarthritis of the knee using 3 T MRI. Osteoarthritis Cartilage. 2007 Jul; 15(7):789-97.
Gündüz K, Pulido JS, Bakri SJ, Amselem L, Petit-Fond E, Link T. Fundus autofluorescence of choroidal melanocytic lesions and the effect of treatment. Trans Am Ophthalmol Soc. 2007; 105:172-8; discussion 178-9.
Link TM, Stahl R, Woertler K. Cartilage imaging: motivation, techniques, current and future significance. Eur Radiol. 2007 May; 17(5):1135-46.
Eckstein F, Burstein D, Link TM. Quantitative MRI of cartilage and bone: degenerative changes in osteoarthritis. NMR Biomed. 2006 Nov; 19(7):822-54.
Bauer JS, Krause SJ, Ross CJ, Krug R, Carballido-Gamio J, Ozhinsky E, Majumdar S, Link TM. Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracy. Radiology. 2006 Nov; 241(2):399-406.
Barr C, Bauer JS, Malfair D, Ma B, Henning TD, Steinbach L, Link TM. MR imaging of the ankle at 3 Tesla and 1.5 Tesla: protocol optimization and application to cartilage, ligament and tendon pathology in cadaver specimens. Eur Radiol. 2007 Jun; 17(6):1518-28.
Majumdar S, Li X, Blumenkrantz G, Saldanha K, Ma CB, Kim H, Lozano J, Link T. MR imaging and early cartilage degeneration and strategies for monitoring regeneration. J Musculoskelet Neuronal Interact. 2006 Oct-Dec; 6(4):382-4.
Bauer JS, Müller D, Rummeny EJ, Link TM. [Fracture diagnosis in osteoporosis]. Radiologe. 2006 Oct; 46(10):839-46.
Link TM, Imhof H. [Introduction to the topic: diagnosis of osteoporosis - a paradigm shift]. Radiologe. 2006 Oct; 46(10):829-30.
Issever AS, Link TM. [New techniques for the diagnosis of osteoporosis]. Radiologe. 2006 Oct; 46(10):870, 872-80.
Daldrup-Link HE, Henning T, Link TM. MR imaging of therapy-induced changes of bone marrow. Eur Radiol. 2007 Mar; 17(3):743-61.
Metz S, Kuhn V, Kettler M, Hudelmaier M, Bonel HM, Waldt S, Hollweck R, Renger B, Rummeny EJ, Link TM. Comparison of different radiography systems in an experimental study for detection of forearm fractures and evaluation of the Müller-AO and Frykman classification for distal radius fractures. Invest Radiol. 2006 Sep; 41(9):681-90.
Mueller D, Link TM, Monetti R, Bauer J, Boehm H, Seifert-Klauss V, Rummeny EJ, Morfill GE, Raeth C. The 3D-based scaling index algorithm: a new structure measure to analyze trabecular bone architecture in high-resolution MR images in vivo. Osteoporos Int. 2006 Oct; 17(10):1483-93.
Blumenkrantz G, Li X, Han ET, Newitt DC, Crane JC, Link TM, Majumdar S. A feasibility study of in vivo T1rho imaging of the intervertebral disc. Magn Reson Imaging. 2006 Oct; 24(8):1001-7.
Seifert-Klauss V, Link T, Heumann C, Luppa P, Haseitl M, Laakmann J, Rattenhuber J, Kiechle M. Influence of pattern of menopausal transition on the amount of trabecular bone loss. Results from a 6-year prospective longitudinal study. Maturitas. 2006 Nov 20; 55(4):317-24.
Lozano J, Li X, Link TM, Safran M, Majumdar S, Ma CB. Detection of posttraumatic cartilage injury using quantitative T1rho magnetic resonance imaging. A report of two cases with arthroscopic findings. J Bone Joint Surg Am. 2006 Jun; 88(6):1349-52.
Carballido-Gamio J, Phan C, Link TM, Majumdar S. Characterization of trabecular bone structure from high-resolution magnetic resonance images using fuzzy logic. Magn Reson Imaging. 2006 Oct; 24(8):1023-9.
Eckstein F, Ateshian G, Burgkart R, Burstein D, Cicuttini F, Dardzinski B, Gray M, Link TM, Majumdar S, Mosher T, Peterfy C, Totterman S, Waterton J, Winalski CS, Felson D. Proposal for a nomenclature for magnetic resonance imaging based measures of articular cartilage in osteoarthritis. Osteoarthritis Cartilage. 2006 Oct; 14(10):974-83.
Phan CM, Matsuura M, Bauer JS, Dunn TC, Newitt D, Lochmueller EM, Eckstein F, Majumdar S, Link TM. Trabecular bone structure of the calcaneus: comparison of MR imaging at 3.0 and 1.5 T with micro-CT as the standard of reference. Radiology. 2006 May; 239(2):488-96.
Bauer JS, Kohlmann S, Eckstein F, Mueller D, Lochmüller EM, Link TM. Structural analysis of trabecular bone of the proximal femur using multislice computed tomography: a comparison with dual X-ray absorptiometry for predicting biomechanical strength in vitro. Calcif Tissue Int. 2006 Feb; 78(2):78-89.
Bauer JS, Müller D, Ambekar A, Dobritz M, Matsuura M, Eckstein F, Rummeny EJ, Link TM. Detection of osteoporotic vertebral fractures using multidetector CT. Osteoporos Int. 2006; 17(4):608-15.
Wiener E, Pautke C, Link TM, Neff A, Kolk A. Comparison of 16-slice MSCT and MRI in the assessment of squamous cell carcinoma of the oral cavity. Eur J Radiol. 2006 Apr; 58(1):113-8.
Phan CM, Link TM, Blumenkrantz G, Dunn TC, Ries MD, Steinbach LS, Majumdar S. MR imaging findings in the follow-up of patients with different stages of knee osteoarthritis and the correlation with clinical symptoms. Eur Radiol. 2006 Mar; 16(3):608-18.
Li X, Han ET, Ma CB, Link TM, Newitt DC, Majumdar S. In vivo 3T spiral imaging based multi-slice T(1rho) mapping of knee cartilage in osteoarthritis. Magn Reson Med. 2005 Oct; 54(4):929-36.
Link TM, Sell CA, Masi JN, Phan C, Newitt D, Lu Y, Steinbach L, Majumdar S. 3.0 vs 1.5 T MRI in the detection of focal cartilage pathology--ROC analysis in an experimental model. Osteoarthritis Cartilage. 2006 Jan; 14(1):63-70.
Lee KY, Masi JN, Sell CA, Schier R, Link TM, Steinbach LS, Safran M, Ma B, Majumdar S. Computer-aided quantification of focal cartilage lesions using MRI: accuracy and initial arthroscopic comparison. Osteoarthritis Cartilage. 2005 Aug; 13(8):728-37.
Link TM, Mischung J, Wörtler K, Burkart A, Rummeny EJ, Imhoff AB. Normal and pathological MR findings in osteochondral autografts with longitudinal follow-up. Eur Radiol. 2006 Jan; 16(1):88-96.
Krug R, Banerjee S, Han ET, Newitt DC, Link TM, Majumdar S. Feasibility of in vivo structural analysis of high-resolution magnetic resonance images of the proximal femur. Osteoporos Int. 2005 Nov; 16(11):1307-14.
Masi JN, Sell CA, Phan C, Han E, Newitt D, Steinbach L, Majumdar S, Link TM. Cartilage MR imaging at 3.0 versus that at 1.5 T: preliminary results in a porcine model. Radiology. 2005 Jul; 236(1):140-50.
Masi JN, Newitt D, Sell CA, Daldrup-Link H, Steinbach L, Majumdar S, Link TM. Optimization of gadodiamide concentration for MR arthrography at 3 T. AJR Am J Roentgenol. 2005 Jun; 184(6):1754-61.
Sell CA, Masi JN, Burghardt A, Newitt D, Link TM, Majumdar S. Quantification of trabecular bone structure using magnetic resonance imaging at 3 Tesla--calibration studies using microcomputed tomography as a standard of reference. Calcif Tissue Int. 2005 May; 76(5):355-64.
Link TM, Guglielmi G, van Kuijk C, Adams JE. Radiologic assessment of osteoporotic vertebral fractures: diagnostic and prognostic implications. Eur Radiol. 2005 Aug; 15(8):1521-32.
Simon G, Link TM, Wörtler K, Doebereiner F, Schulte-Frohlinde E, Daldrup-Link H, Settles M, Rummeny EJ. Detection of hepatocellular carcinoma: comparison of Gd-DTPA- and ferumoxides-enhanced MR imaging. Eur Radiol. 2005 May; 15(5):895-903.
Hudelmaier M, Kollstedt A, Lochmüller EM, Kuhn V, Eckstein F, Link TM. Gender differences in trabecular bone architecture of the distal radius assessed with magnetic resonance imaging and implications for mechanical competence. Osteoporos Int. 2005 Sep; 16(9):1124-33.
Metz S, Damoser P, Hollweck R, Roggel R, Engelke C, Woertler K, Renger B, Rummeny EJ, Link TM. Chest radiography with a digital flat-panel detector: experimental receiver operating characteristic analysis. Radiology. 2005 Mar; 234(3):776-84.
Patel PV, Prevrhal S, Bauer JS, Phan C, Eckstein F, Lochmüller EM, Majumdar S, Link TM. Trabecular bone structure obtained from multislice spiral computed tomography of the calcaneus predicts osteoporotic vertebral deformities. J Comput Assist Tomogr. 2005 Mar-Apr; 29(2):246-53.
Waldt S, Bruegel M, Ganter K, Kuhn V, Link TM, Rummeny EJ, Woertler K. Comparison of multislice CT arthrography and MR arthrography for the detection of articular cartilage lesions of the elbow. Eur Radiol. 2005 Apr; 15(4):784-91.
Boehm HF, Eckstein F, Wunderer C, Kuhn V, Lochmueller EM, Schreiber K, Mueller D, Rummeny EJ, Link TM. Improved performance of hip DXA using a novel region of interest in the upper part of the femoral neck: in vitro study using bone strength as a standard of reference. J Clin Densitom. 2005; 8(4):488-94.
Daldrup-Link HE, Rudelius M, Piontek G, Metz S, Bräuer R, Debus G, Corot C, Schlegel J, Link TM, Peschel C, Rummeny EJ, Oostendorp RA. Migration of iron oxide-labeled human hematopoietic progenitor cells in a mouse model: in vivo monitoring with 1.5-T MR imaging equipment. Radiology. 2005 Jan; 234(1):197-205.
Blumenkrantz G, Lindsey CT, Dunn TC, Jin H, Ries MD, Link TM, Steinbach LS, Majumdar S. A pilot, two-year longitudinal study of the interrelationship between trabecular bone and articular cartilage in the osteoarthritic knee. Osteoarthritis Cartilage. 2004 Dec; 12(12):997-1005.
Beer A, Saar B, Zantl N, Link TM, Roggel R, Hwang SL, Schwaibold H, Rummeny EJ. MR cystography for bladder tumor detection. Eur Radiol. 2004 Dec; 14(12):2311-9.
Eckstein F, Fischbeck M, Kuhn V, Link TM, Priemel M, Lochmüller EM. Determinants and heterogeneity of mechanical competence throughout the thoracolumbar spine of elderly women and men. Bone. 2004 Aug; 35(2):364-74.
Link TM, Bauer J, Kollstedt A, Stumpf I, Hudelmaier M, Settles M, Majumdar S, Lochmüller EM, Eckstein F. Trabecular bone structure of the distal radius, the calcaneus, and the spine: which site predicts fracture status of the spine best? Invest Radiol. 2004 Aug; 39(8):487-97.
Nägele E, Kuhn V, Vogt H, Link TM, Müller R, Lochmüller EM, Eckstein F. Technical considerations for microstructural analysis of human trabecular bone from specimens excised from various skeletal sites. Calcif Tissue Int. 2004 Jul; 75(1):15-22.
Boehm HF, Link TM. Bone imaging: traditional techniques and their interpretation. Curr Osteoporos Rep. 2004 Jun; 2(2):41-6.
Link TM, Majumdar S. Current diagnostic techniques in the evaluation of bone architecture. Curr Osteoporos Rep. 2004 Jun; 2(2):47-52.
Bauer JS, Issever AS, Fischbeck M, Burghardt A, Eckstein F, Rummeny EJ, Majumdar S, Link TM. [Multislice-CT for structure analysis of trabecular bone - a comparison with micro-CT and biomechanical strength]. Rofo. 2004 May; 176(5):709-18.
Link TM, Koppers BB, Licht T, Bauer J, Lu Y, Rummeny EJ. In vitro and in vivo spiral CT to determine bone mineral density: initial experience in patients at risk for osteoporosis. Radiology. 2004 Jun; 231(3):805-11.
Brügel M, Link TM, Rummeny EJ, Lange P, Theisen J, Dobritz M. Assessment of vascular invasion in pancreatic head cancer with multislice spiral CT: value of multiplanar reconstructions. Eur Radiol. 2004 Jul; 14(7):1188-95.
Lindsey CT, Narasimhan A, Adolfo JM, Jin H, Steinbach LS, Link T, Ries M, Majumdar S. Magnetic resonance evaluation of the interrelationship between articular cartilage and trabecular bone of the osteoarthritic knee. Osteoarthritis Cartilage. 2004 Feb; 12(2):86-96.
Hudelmaier M, Kuhn V, Lochmüller EM, Well H, Priemel M, Link TM, Eckstein F. Can geometry-based parameters from pQCT and material parameters from quantitative ultrasound (QUS) improve the prediction of radial bone strength over that by bone mass (DXA)? Osteoporos Int. 2004 May; 15(5):375-81.
Eckstein F, Wunderer C, Boehm H, Kuhn V, Priemel M, Link TM, Lochmüller EM. Reproducibility and side differences of mechanical tests for determining the structural strength of the proximal femur. J Bone Miner Res. 2004 Mar; 19(3):379-85.
Ott K, Fink U, Becker K, Stahl A, Dittler HJ, Busch R, Stein H, Lordick F, Link T, Schwaiger M, Siewert JR, Weber WA. Prediction of response to preoperative chemotherapy in gastric carcinoma by metabolic imaging: results of a prospective trial. J Clin Oncol. 2003 Dec 15; 21(24):4604-10.
Daldrup-Link HE, Kaiser A, Helbich T, Werner M, Bjørnerud A, Link TM, Rummeny EJ. Macromolecular contrast medium (feruglose) versus small molecular contrast medium (gadopentetate) enhanced magnetic resonance imaging: differentiation of benign and malignant breast lesions. Acad Radiol. 2003 Nov; 10(11):1237-46.
Daldrup-Link HE, Rydland J, Helbich TH, Bjørnerud A, Turetschek K, Kvistad KA, Kaindl E, Link TM, Staudacher K, Shames D, Brasch RC, Haraldseth O, Rummeny EJ. Quantification of breast tumor microvascular permeability with feruglose-enhanced MR imaging: initial phase II multicenter trial. Radiology. 2003 Dec; 229(3):885-92.
Daldrup-Link HE, Rudelius M, Oostendorp RA, Settles M, Piontek G, Metz S, Rosenbrock H, Keller U, Heinzmann U, Rummeny EJ, Schlegel J, Link TM. Targeting of hematopoietic progenitor cells with MR contrast agents. Radiology. 2003 Sep; 228(3):760-7.
Weber WA, Petersen V, Schmidt B, Tyndale-Hines L, Link T, Peschel C, Schwaiger M. Positron emission tomography in non-small-cell lung cancer: prediction of response to chemotherapy by quantitative assessment of glucose use. J Clin Oncol. 2003 Jul 15; 21(14):2651-7.
Link TM, Majumdar S. Osteoporosis imaging. Radiol Clin North Am. 2003 Jul; 41(4):813-39.
Bettin D, Böhm H, Clatworthy M, Zurakowski D, Link TM. Regeneration of the donor side after autogenous fibula transplantation in 53 patients: evaluation by dual x-ray absorptiometry. Acta Orthop Scand. 2003 Jun; 74(3):332-6.
Metz S, Daldrup-Unk HE, Richter T, Räth C, Ebert W, Settles M, Rummeny EJ, Link TM, Piert M. Detection and quantification of breast tumor necrosis with MR imaging: value of the necrosis-avid contrast agent Gadophrin-3. Acad Radiol. 2003 May; 10(5):484-90.
Boehm HF, Raeth C, Monetti RA, Mueller D, Newitt D, Majumdar S, Rummeny E, Morfill G, Link TM. Local 3D scaling properties for the analysis of trabecular bone extracted from high-resolution magnetic resonance imaging of human trabecular bone: comparison with bone mineral density in the prediction of biomechanical strength in vitro. Invest Radiol. 2003 May; 38(5):269-80.
Rudelius M, Daldrup-Link HE, Heinzmann U, Piontek G, Settles M, Link TM, Schlegel J. Highly efficient paramagnetic labelling of embryonic and neuronal stem cells. Eur J Nucl Med Mol Imaging. 2003 Jul; 30(7):1038-44.
Link TM, Steinbach LS, Ghosh S, Ries M, Lu Y, Lane N, Majumdar S. Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findings. Radiology. 2003 Feb; 226(2):373-81.
Issever AS, Vieth V, Lotter A, Meier N, Laib A, Newitt D, Majumdar S, Link TM. Local differences in the trabecular bone structure of the proximal femur depicted with high-spatial-resolution MR imaging and multisection CT. Acad Radiol. 2002 Dec; 9(12):1395-406.
Stahl A, Ott K, Weber WA, Becker K, Link T, Siewert JR, Schwaiger M, Fink U. FDG PET imaging of locally advanced gastric carcinomas: correlation with endoscopic and histopathological findings. Eur J Nucl Med Mol Imaging. 2003 Feb; 30(2):288-95.
Link TM, Vieth V, Langenberg R, Meier N, Lotter A, Newitt D, Majumdar S. Structure analysis of high resolution magnetic resonance imaging of the proximal femur: in vitro correlation with biomechanical strength and BMD. Calcif Tissue Int. 2003 Feb; 72(2):156-65.
Link TM. High-resolution magnetic resonance imaging to assess trabecular bone structure in patients after transplantation: a review. Top Magn Reson Imaging. 2002 Oct; 13(5):365-75.
Link TM, Vieth V, Stehling C, Lotter A, Beer A, Newitt D, Majumdar S. High-resolution MRI vs multislice spiral CT: which technique depicts the trabecular bone structure best? Eur Radiol. 2003 Apr; 13(4):663-71.
van Rijn RR, van der Sluis IM, Link TM, Grampp S, Guglielmi G, Imhof H, Glüer C, Adams JE, van Kuijk C. Bone densitometry in children: a critical appraisal. Eur Radiol. 2003 Apr; 13(4):700-10.
Link TM, Bauer JS. Imaging of trabecular bone structure. Semin Musculoskelet Radiol. 2002 Sep; 6(3):253-61.
Daldrup-Link HE, Kaiser A, Link TM, Settles M, Helbich T, Werner M, Roberts TP, Rummeny EJ. Comparison between gadopentetate and feruglose (Clariscan)-enhanced MR-mammography: preliminary clinical experience. Acad Radiol. 2002 Aug; 9 Suppl 2:S343-7.
Ludwig K, Diederich S, Wormanns D, Link TM, Lenzen H, Heindel W. [Selenium-based digital radiography of the cervical spine: comparison with screen-film radiography for the depiction of anatomic details]. Rofo. 2002 Aug; 174(8):1028-32.
Hellerhoff KJ, Helmberger H, Rösch T, Settles MR, Link TM, Rummeny EJ. Dynamic MR pancreatography after secretin administration: image quality and diagnostic accuracy. AJR Am J Roentgenol. 2002 Jul; 179(1):121-9.
Hackenberg L, Link T, Liljenqvist U. Axial and tangential fixation strength of pedicle screws versus hooks in the thoracic spine in relation to bone mineral density. Spine (Phila Pa 1976). 2002 May 01; 27(9):937-42.
Liljenqvist UR, Allkemper T, Hackenberg L, Link TM, Steinbeck J, Halm HF. Analysis of vertebral morphology in idiopathic scoliosis with use of magnetic resonance imaging and multiplanar reconstruction. J Bone Joint Surg Am. 2002 Mar; 84(3):359-68.
Daldrup-Link HE, Rummeny EJ, Ihssen B, Kienast J, Link TM. Iron-oxide-enhanced MR imaging of bone marrow in patients with non-Hodgkin's lymphoma: differentiation between tumor infiltration and hypercellular bone marrow. Eur Radiol. 2002 Jun; 12(6):1557-66.
Beuf O, Ghosh S, Newitt DC, Link TM, Steinbach L, Ries M, Lane N, Majumdar S. Magnetic resonance imaging of normal and osteoarthritic trabecular bone structure in the human knee. Arthritis Rheum. 2002 Feb; 46(2):385-93.
Ludwig K, Lenzen H, Kamm KF, Link TM, Diederich S, Wormanns D, Heindel W. Performance of a flat-panel detector in detecting artificial bone lesions: comparison with conventional screen-film and storage-phosphor radiography. Radiology. 2002 Feb; 222(2):453-9.
Link TM, Kisters K, Kempkes M, Kosch M, Newitt D, Lu Y, Waldt S, Majumdar S. Changes in calcaneal trabecular bone structure assessed with high-resolution MR imaging in patients with kidney transplantation. Osteoporos Int. 2002; 13(2):119-29.
Beer A, Saar B, Link TM, Settles M, Drews C, Schwaibold H, Rummeny EJ. [Virtual endoscopy of the urinary tract from T(2)-weighted and gadolinium-enhanced T(1)-weighted MR urographic images]. Rofo. 2001 Nov; 173(11):997-1005.
Link TM, Vieth V, Matheis J, Newitt D, Lu Y, Rummeny EJ, Majumdar S. Bone structure of the distal radius and the calcaneus vs BMD of the spine and proximal femur in the prediction of osteoporotic spine fractures. Eur Radiol. 2002 Feb; 12(2):401-8.
Daldrup-Link HE, Franzius C, Link TM, Laukamp D, Sciuk J, Jürgens H, Schober O, Rummeny EJ. Whole-body MR imaging for detection of bone metastases in children and young adults: comparison with skeletal scintigraphy and FDG PET. AJR Am J Roentgenol. 2001 Jul; 177(1):229-36.
Daldrup-Link HE, Reinländer C, Link TM, Richter KJ, Könemann S, Rummeny EJ. [Experimental studies of the value of SPIO for MRI of bone marrow before and after whole body irradiation]. Rofo. 2001 Jun; 173(6):547-53.
Woertler K, Blasius S, Brinkschmidt C, Hillmann A, Link TM, Heindel W. Periosteal chondroma: MR characteristics. J Comput Assist Tomogr. 2001 May-Jun; 25(3):425-30.
Sandherr M, von Schilling C, Link T, Stock K, von Bubnoff N, Peschel C, Avril N. Pitfalls in imaging Hodgkin's disease with computed tomography and positron emission tomography using fluorine-18-fluorodeoxyglucose. Ann Oncol. 2001 May; 12(5):719-22.
Vieth V, Link TM, Lotter A, Persigehl T, Newitt D, Heindel W, Majumdar S. Does the trabecular bone structure depicted by high-resolution MRI of the calcaneus reflect the true bone structure? Invest Radiol. 2001 Apr; 36(4):210-7.
Liljenqvist U, Hackenberg L, Link T, Halm H. Pullout strength of pedicle screws versus pedicle and laminar hooks in the thoracic spine. Acta Orthop Belg. 2001 Apr; 67(2):157-63.
Hillmann A, Link TM, Ozaki T, Vestring T, Winkelmann W. Computed direct magnification radiography of bone tumors. J Cancer Res Clin Oncol. 2001 Feb; 127(2):116-22.
Wormanns D, Diederich S, Lenzen H, Lange P, Link TM, Ludwig K, Papke K, Hagedorn C, Heindel W. Abdominal spiral CT in children: which radiation exposure is required? Eur Radiol. 2001; 11(11):2262-6.
Daldrup-Link HE, Link TM, Möller HE, Wiedermann D, Bonnemain B, Corot C, Rummeny EJ. Carboxymethyldextran-A2-Gd-DOTA enhancement patterns in the abdomen and pelvis in an animal model. Eur Radiol. 2001; 11(7):1276-84.
Link TM. Changes in trabecular bone structure assessed by high-resolution MRI in patients after transplantation. Adv Exp Med Biol. 2001; 496:31-6.
Juergens KU, Bullmann V, Link TM, Brinkschmidt C, Heindel W. Desmoplastic fibroma in the thoracic spine: an unusual localization of a rare primary bone tumor. Eur Radiol. 2001; 11(2):273-5.
Diederich S, Link TM, Zühlsdorf H, Steinmeyer E, Wormanns D, Heindel W. Pulmonary manifestations of Hodgkin's disease: radiographic and CT findings. Eur Radiol. 2001; 11(11):2295-305.
Link TM, Lotter A, Beyer F, Christiansen S, Newitt D, Lu Y, Schmid C, Majumdar S. Changes in calcaneal trabecular bone structure after heart transplantation: an MR imaging study. Radiology. 2000 Dec; 217(3):855-62.
Majumdar S, Link TM, Millard J, Lin JC, Augat P, Newitt D, Lane N, Genant HK. In vivo assessment of trabecular bone structure using fractal analysis of distal radius radiographs. Med Phys. 2000 Nov; 27(11):2594-9.
Kosch M, Hausberg M, Link T, Kemkes M, Barenbrock M, Dietl KH, Matzkies F, Rahn KH, Kisters K. Measurement of skeletal status after renal transplantation by quantitative ultrasound. Clin Nephrol. 2000 Jul; 54(1):15-21.
Ludwig K, Link TM, Fiebich M, Renger B, Diederich S, Oelerich M, Lenzen H, Heindel W. Selenium-based digital radiography in the detection of bone lesions: preliminary experience with experimentally created defects. Radiology. 2000 Jul; 216(1):220-4.
Halm H, Niemeyer T, Link T, Liljenqvist U. Segmental pedicle screw instrumentation in idiopathic thoracolumbar and lumbar scoliosis. Eur Spine J. 2000 Jun; 9(3):191-7.
Liljenqvist UR, Link TM, Halm HF. Morphometric analysis of thoracic and lumbar vertebrae in idiopathic scoliosis. Spine (Phila Pa 1976). 2000 May 15; 25(10):1247-53.
Böttner F, Wörtler K, Link T. Osteoid osteoma. J Bone Joint Surg Br. 2000 Mar; 82(2):306-7.
Genant HK, Gordon C, Jiang Y, Link TM, Hans D, Majumdar S, Lang TF. Advanced imaging of the macrostructure and microstructure of bone. Horm Res. 2000; 54 Suppl 1:24-30.
Daldrup-Link HE, Link TM, Rummeny EJ, August C, Könemann S, Jürgens H, Heindel W. Assessing permeability alterations of the blood-bone marrow barrier due to total body irradiation: in vivo quantification with contrast enhanced magnetic resonance imaging. Bone Marrow Transplant. 2000 Jan; 25(1):71-8.
Link TM, Berning W, Scherf S, Joosten U, Joist A, Engelke K, Daldrup-Link HE. CT of metal implants: reduction of artifacts using an extended CT scale technique. J Comput Assist Tomogr. 2000 Jan-Feb; 24(1):165-72.
Link TM, Dören M, Lewing G, Meier N, Heinecke A, Rummeny E. Cross-sectional area of lumbar vertebrae in peri- and postmenopausal patients with and without osteoporosis. Osteoporos Int. 2000; 11(4):304-9.
Stäbler A, Schneider P, Link TM, Schöps P, Springer OS, Dürr HR, Reiser M. Intravertebral vacuum phenomenon following fractures: CT study on frequency and etiology. J Comput Assist Tomogr. 1999 Nov-Dec; 23(6):976-80.
Böttner F, Link T, Wörtler K. [Primary non-Hodgkin lymphoma of the knee joint involving the synovial membrane]. Rofo. 1999 Sep; 171(3):266-7.
Waldt S, Meier N, Renger B, Lenzen H, Fiebich M, Rummeny EJ, Link TM. [The texture-analysis of high-resolution computed tomograms as an additional procedure in osteoporosis diagnosis: in-vitro studies on vertebral segments]. Rofo. 1999 Aug; 171(2):136-42.
Genant HK, Gordon C, Jiang Y, Lang TF, Link TM, Majumdar S. Advanced imaging of bone macro and micro structure. Bone. 1999 Jul; 25(1):149-52.
Majumdar S, Lin J, Link T, Millard J, Augat P, Ouyang X, Newitt D, Gould R, Kothari M, Genant H. Fractal analysis of radiographs: assessment of trabecular bone structure and prediction of elastic modulus and strength. Med Phys. 1999 Jul; 26(7):1330-40.
Daldrup HE, Link TM, Blasius S, Strozyk A, Könemann S, Jürgens H, Rummeny EJ. Monitoring radiation-induced changes in bone marrow histopathology with ultra-small superparamagnetic iron oxide (USPIO)-enhanced MRI. J Magn Reson Imaging. 1999 May; 9(5):643-52.
Konermann W, Stubbe F, Link T, Meier N. [Axial compressive strength of thoraco-lumbar vertebrae--an experimental biomechanical study]. Z Orthop Ihre Grenzgeb. 1999 May-Jun; 137(3):223-31.
Link TM, Brinkschmidt C, Lindner N, Wörtler K, Heindel W. [Primary bone tumors and "tumor-like lesions" of the shoulder. Their histopathology and imaging]. Rofo. 1999 May; 170(5):507-13.
Lin JC, Grampp S, Link T, Kothari M, Newitt DC, Felsenberg D, Majumdar S. Fractal analysis of proximal femur radiographs: correlation with biomechanical properties and bone mineral density. Osteoporos Int. 1999; 9(6):516-24.
Link TM, Majumdar S, Grampp S, Guglielmi G, van Kuijk C, Imhof H, Glueer C, Adams JE. Imaging of trabecular bone structure in osteoporosis. Eur Radiol. 1999; 9(9):1781-8.
Majumdar S, Link TM, Augat P, Lin JC, Newitt D, Lane NE, Genant HK. Trabecular bone architecture in the distal radius using magnetic resonance imaging in subjects with fractures of the proximal femur. Magnetic Resonance Science Center and Osteoporosis and Arthritis Research Group. Osteoporos Int. 1999; 10(3):231-9.
Hans D, Wu C, Njeh CF, Zhao S, Augat P, Newitt D, Link T, Lu Y, Majumdar S, Genant HK. Ultrasound velocity of trabecular cubes reflects mainly bone density and elasticity. Calcif Tissue Int. 1999 Jan; 64(1):18-23.
Millard J, Augat P, Link TM, Kothari M, Newitt DC, Genant HK, Majumdar S. Power spectral analysis of vertebral trabecular bone structure from radiographs: orientation dependence and correlation with bone mineral density and mechanical properties. Calcif Tissue Int. 1998 Dec; 63(6):482-9.
Link TM, Majumdar S, Augat P, Lin JC, Newitt D, Lane NE, Genant HK. Proximal femur: assessment for osteoporosis with T2* decay characteristics at MR imaging. Radiology. 1998 Nov; 209(2):531-6.
Daldrup H, Shames DM, Wendland M, Okuhata Y, Link TM, Rosenau W, Lu Y, Brasch RC. Correlation of dynamic contrast-enhanced MR imaging with histologic tumor grade: comparison of macromolecular and small-molecular contrast media. AJR Am J Roentgenol. 1998 Oct; 171(4):941-9.
Link TM, Haeussler MD, Poppek S, Woertler K, Blasius S, Lindner N, Rummeny EJ. Malignant fibrous histiocytoma of bone: conventional X-ray and MR imaging features. Skeletal Radiol. 1998 Oct; 27(10):552-8.
Ouyang X, Majumdar S, Link TM, Lu Y, Augat P, Lin J, Newitt D, Genant HK. Morphometric texture analysis of spinal trabecular bone structure assessed using orthogonal radiographic projections. Med Phys. 1998 Oct; 25(10):2037-45.
Link TM, Lin JC, Newitt D, Meier N, Waldt S, Majumdar S. [Computer-assisted structure analysis of trabecular bone in the diagnosis of osteoporosis]. Radiologe. 1998 Oct; 38(10):853-9.
Link TM, Majumdar S, Augat P, Lin JC, Newitt D, Lu Y, Lane NE, Genant HK. In vivo high resolution MRI of the calcaneus: differences in trabecular structure in osteoporosis patients. J Bone Miner Res. 1998 Jul; 13(7):1175-82.
Daldrup HE, Link TM, Wörtler K, Reimer P, Rummeny EJ. MR imaging of thoracic tumors in pediatric patients. AJR Am J Roentgenol. 1998 Jun; 170(6):1639-44.
Majumdar S, Kothari M, Augat P, Newitt DC, Link TM, Lin JC, Lang T, Lu Y, Genant HK. High-resolution magnetic resonance imaging: three-dimensional trabecular bone architecture and biomechanical properties. Bone. 1998 May; 22(5):445-54.
Ozaki T, Hillmann A, Blasius S, Link T, Winkelmann W. Multicentric malignant transformation of multiple exostoses. Skeletal Radiol. 1998 Apr; 27(4):233-6.
Wörtler K, Link TM, Blasius S, Rödl R, Vestring T. [Pigmented villonodular synovitis of the hip]. Rofo. 1998 Apr; 168(4):410-2.
Augat P, Link T, Lang TF, Lin JC, Majumdar S, Genant HK. Anisotropy of the elastic modulus of trabecular bone specimens from different anatomical locations. Med Eng Phys. 1998 Mar; 20(2):124-31.
Daldrup H, Shames DM, Wendland M, Okuhata Y, Link TM, Rosenau W, Lu Y, Brasch RC. Correlation of dynamic contrast-enhanced magnetic resonance imaging with histologic tumor grade: comparison of macromolecular and small-molecular contrast media. Pediatr Radiol. 1998 Feb; 28(2):67-78.
Link TM, Majumdar S, Lin JC, Newitt D, Augat P, Ouyang X, Mathur A, Genant HK. A comparative study of trabecular bone properties in the spine and femur using high resolution MRI and CT. J Bone Miner Res. 1998 Jan; 13(1):122-32.
Link TM, Majumdar S, Lin JC, Augat P, Gould RG, Newitt D, Ouyang X, Lang TF, Mathur A, Genant HK. Assessment of trabecular structure using high resolution CT images and texture analysis. J Comput Assist Tomogr. 1998 Jan-Feb; 22(1):15-24.
Leifke E, Körner HC, Link TM, Behre HM, Peters PE, Nieschlag E. Effects of testosterone replacement therapy on cortical and trabecular bone mineral density, vertebral body area and paraspinal muscle area in hypogonadal men. Eur J Endocrinol. 1998 Jan; 138(1):51-8.
Link TM, Majumdar S, Peterfy C, Daldrup HE, Uffmann M, Dowling C, Steinbach L, Genant HK. High resolution MRI of small joints: impact of spatial resolution on diagnostic performance and SNR. Magn Reson Imaging. 1998; 16(2):147-55.
Veenland JF, Link TM, Konermann W, Meier N, Grashuis JL, Gelsema ES. Unraveling the role of structure and density in determining vertebral bone strength. Calcif Tissue Int. 1997 Dec; 61(6):474-9.
Liljenqvist UR, Halm HF, Link TM. Pedicle screw instrumentation of the thoracic spine in idiopathic scoliosis. Spine (Phila Pa 1976). 1997 Oct 01; 22(19):2239-45.
Behre HM, Kliesch S, Leifke E, Link TM, Nieschlag E. Long-term effect of testosterone therapy on bone mineral density in hypogonadal men. J Clin Endocrinol Metab. 1997 Aug; 82(8):2386-90.
Ozaki T, Lindner N, Hillmann A, Link T, Winkelmann W. Transarticular invasion of iliopelvic sarcomas into the sacrum. Radiological analysis of 47 cases. Acta Orthop Scand. 1997 Aug; 68(4):381-3.
Link TM, Majumdar S, Konermann W, Meier N, Lin JC, Newitt D, Ouyang X, Peters PE, Genant HK. Texture analysis of direct magnification radiographs of vertebral specimens: correlation with bone mineral density and biomechanical properties. Acad Radiol. 1997 Mar; 4(3):167-76.
Link TM, Lindner N, Haeussler M, Reimer P, Allkemper T, Jerosch J, Peterfy C, Majumdar S, Peters PE. Artificially produced cartilage lesions in small joints: detection with optimized MRI-sequences. Magn Reson Imaging. 1997; 15(8):949-56.
Daldrup HE, Schuierer G, Link TM, Moeller H, Bick U, Kurlemann G, Peters PE. Evaluation of myelination and myelination disorders with turbo inversion recovery magnetic resonance imaging. Eur Radiol. 1997; 7(9):1478-84.
Müller-Miny H, Link T, Braun-Anhalt I, Dietl KH, Peters PE. [Comparison between direct radiographic enlargement and mammography technique in detection of osseous changes of the hand skeleton in hyperparathyroidism]. Radiologe. 1996 Oct; 36(10):834-9.
Link TM, Hillmann A, Erlemann R, Grönefeld A, Häussler M, Heppe AE, Vestring T, Peters PE. Imaging of bone tumors: evaluation of direct magnification radiography. Skeletal Radiol. 1996 Jul; 25(5):441-7.
Blasius S, Link TM, Hillmann A, Rödl R, Edel G, Winkelmann W. Intracortical low grade osteosarcoma. A unique case and review of the literature on intracortical osteosarcoma. Gen Diagn Pathol. 1996 Mar; 141(3-4):273-8.
Link TM, Meier N, Rummeny EJ, Garmann S, Steinbeck J, Schröder M, Oelerich M, Häussler MD. Artificial spine fractures: detection with helical and conventional CT. Radiology. 1996 Feb; 198(2):515-9.
Link TM, Bongartz GM, Böger K, Daldrup H, Schmitz-Linneweber B, Peters PE. [Use of gadoteridol in MR diagnosis of rheumatoid changes in the joints]. Radiologe. 1996 Feb; 36(2):141-7.
Ozaki T, Lindner N, Hoffmann C, Hillmann A, Rödl R, Blasius S, Link T, Winkelmann W, Jürgens H. Ewing's sarcoma of the ribs. A report from the cooperative Ewing's sarcoma study. Eur J Cancer. 1995 Dec; 31A(13-14):2284-8.
Link TM, Reimer P, Rummeny EJ, Schuierer G, Grenzebach U, Peters PE. [The MRT of the orbit: the value of T1-weighted frequency-selective fat saturation at 1.0 and 1.5 tesla]. Rofo. 1995 Nov; 163(5):406-10.
Link TM, Schuierer G, Hufendiek A, Horch C, Peters PE. Substantial head trauma: value of routine CT examination of the cervicocranium. Radiology. 1995 Sep; 196(3):741-5.
Marx C, Link TM, Blasius S, Rödl R. [Tumorous space-occupying lesion of the ilium]. Radiologe. 1995 Sep; 35(9):617-9.
Kerber S, Link TM, Kleinen T, Martinez-Rubio A, Meier N, Fahrenkamp A, Bongartz G, Block M, Peters PE, Breithardt G. [In vitro validation of intravascular ultrasound, computerized and magnetic resonance tomography in diagnosis of atherosclerotic vascular segments in comparison with direct magnification radiography]. Z Kardiol. 1995 Jun; 84(6):423-35.
Link TM, Sciuk J, Fründt H, Konermann W, Schober O, Peters PE. [Spinal metastases. Value of diagnostic procedures in the initial diagnosis and follow-up]. Radiologe. 1995 Jan; 35(1):21-7.
Kessler T, Link TM, Overbeck J, Lange T, Klein W. [Follow-up of fracture healing--indications and clinical relevance of direct radiographic magnification in comparison with conventional roentgen imaging]. Unfallchirurg. 1994 Dec; 97(12):619-24.
Link TM, Schuierer G, Hufendiek A, Peters PE. [Fractures of the cervical spine. Diagnosis in multiple trauma patients]. Radiologe. 1994 Dec; 34(12):721-7.
Link TM, Kerber S, Fechtrup C, Pöppelmann M, Kleinen T, Blasius S, Budde T, Breithardt G, Peters PE. [Significance of intravascular ultrasound in arteriosclerotic calcified intima plaques: in vitro comparison of 20 and 12.5 MHz transducers]. Rofo. 1994 Dec; 161(6):540-6.
Link TM, Rummeny EJ, Lenzen H, Reuter I, Roos N, Peters PE. Artificial bone erosions: detection with magnification radiography versus conventional high-resolution radiography. Radiology. 1994 Sep; 192(3):861-4.
Link TM, Fiebich M, Gaubitz M, Krause F, Vestring T, Schneider M, Peters PE. [Value of direct radiographic enlargement (DIMA) in early detection of rheumatic inflammatory lesions. Comparative evaluation with high resolution conventional imaging technique]. Radiologe. 1994 Jul; 34(7):405-10.
Link TM, Kerber S, Pöppelmann M, Kleinen T, Krings W, Breithardt G, Blasius S, Peters PE. In vitro correlation of intravascular ultrasound and direct magnification radiography for calcified arterial lesions. Invest Radiol. 1994 Apr; 29(4):420-6.
Kerber S, Link TM, Fechtrup C, Krings W, Pöppelmann M, Fahrenkamp A, Budde T, Peters PE, Böcker W, Breithardt G. [Intravascular ultrasound in peripheral calcified vascular lesions: comparison with direct magnification radiography]. Z Kardiol. 1993 Oct; 82(10):610-7.
Link TM, Koc F, Peters PE. [State of the art of selective small bowel enema. Indications and results]. Radiologe. 1993 Jun; 33(6):343-6.
Link TM, Gaubitz M, Lenzen H, Müller-Miny H, Schneider M, Peters PE. [Clinical use of magnification radiography in rheumatologic differential diagnosis]. Z Rheumatol. 1993 May-Jun; 52(3):161-6.
Link TM, Greiner C, Peters PE. [Mediastinal spread in a brain tumor]. Radiologe. 1992 Dec; 32(12):619-20.
Link TM, Anger K, Hebestreit HP, Bade J. [The lung and mediastinal metastases of a hepatocellular carcinoma. Enhancement in the liver function scintigram with 99mTc-IODIDA]. Rofo. 1992 Jul; 157(1):101-2.
Thomas Link, MD, PhD | UCSF Radiology

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