Yusuke Yagi, MD



Yagi Y, Kimura H, Okuda H, Ono M, Nakamoto Y, Togashi K, Saji H. Evaluation of [18F]pitavastatin as a positron emission tomography tracer for in vivo organic transporter polypeptide function. Nucl Med Biol. 2019 Aug 14; 74-75:25-31.
Mori D, Kimura H, Kawashima H, Yagi Y, Arimitsu K, Ono M, Saji H. Development of 99mTc radiolabeled A85380 derivatives targeting cerebral nicotinic acetylcholine receptor: Novel radiopharmaceutical ligand 99mTc-A-YN-IDA-C4. Bioorg Med Chem. 2019 Jul 31.
Chen X, Fritz A, Werner RA, Nose N, Yagi Y, Kimura H, Rowe SP, Koshino K, Decker M, Higuchi T. Initial Evaluation of AF78: a Rationally Designed Fluorine-18-Labelled PET Radiotracer Targeting Norepinephrine Transporter. Mol Imaging Biol. 2019 Jul 22.
Kimura H, Yagi Y, Mikamo M, Kazuya M, Kagawa S, Arimitsu K, Higashi T, Nishii R, Ono M, Nakamoto Y, Togashi K, Kusuhara H, Saji H. Evaluation of transporter-mediated hepatobiliary transport of newly developed 18F-labeled pitavastatin derivative, PTV-F1, in rats by PET imaging. Drug Metab Pharmacokinet. 2019 Jun 04.
Kimura H, Ueda M, Kawashima H, Arimitsu K, Yagi Y, Saji H. Synthesis and biological evaluation of Tc-99m-cyclopentadienyltricarbonyl-technetium-labeled A-85380: An imaging probe for single-photon emission computed tomography investigation of nicotinic acetylcholine receptors in the brain. Bioorg Med Chem. 2019 Jun 01; 27(11):2245-2252.
Yagi Y, Shimizu Y, Arimitsu K, Nakamoto Y, Higuchi T, Togashi K, Kimura H. Efficient gallium-68 radiolabeling reaction of DOTA derivatives using a resonant-type microwave reactor. J Labelled Comp Radiopharm. 2019 Mar; 62(3):132-138.
Kobayashi T, Yagi Y, Nakamura T. Comprehensive prediction of target RNA editing sites for PLS-class PPR proteins in Arabidopsis thaliana. Plant Cell Physiol. 2019 Jan 03.
Ishida T, Iizuka M, Ou Y, Morisawa S, Hirata A, Yagi Y, Jobu K, Morita Y, Miyamura M. Juzentaihoto Suppresses Muscle Atrophy in Streptozotocin-Induced Diabetic Mice. Biol Pharm Bull. 2019; 42(7):1128-1133.
Ishida T, Iizuka M, Ou Y, Morisawa S, Hirata A, Yagi Y, Jobu K, Morita Y, Miyamura M. Juzentaihoto hot water extract alleviates muscle atrophy and improves motor function in streptozotocin-induced diabetic oxidative stress mice. J Nat Med. 2019 Jan; 73(1):202-209.
Matsumoto K, Takeuchi S, Uehara Y, Matsushita M, Arise K, Morimoto N, Yagi Y, Seo H. Transmission of methicillin-resistant Staphylococcus aureus in an acute care hospital in Japan. J Gen Fam Med. 2019 Jan; 20(1):13-18.
Matsuura S, Katsumi H, Suzuki H, Hirai N, Hayashi H, Koshino K, Higuchi T, Yagi Y, Kimura H, Sakane T, Yamamoto A. l-Serine-modified polyamidoamine dendrimer as a highly potent renal targeting drug carrier. Proc Natl Acad Sci U S A. 2018 10 09; 115(41):10511-10516.
Kimura H, Yamauchi S, Kawashima H, Arimitsu K, Yagi Y, Nakamoto Y, Togashi K, Ono M, Saji H. Synthesis and evaluation of a [18F]formyl-Met-Leu-Phe derivative: A positron emission tomography imaging probe for bacterial infections. Bioorg Med Chem Lett. 2018 09 15; 28(17):2949-2952.
Matsuoka D, Watanabe H, Shimizu Y, Kimura H, Yagi Y, Kawai R, Ono M, Saji H. Structure-activity relationships of succinimidyl-Cys-C(O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen. Bioorg Med Chem. 2018 05 15; 26(9):2291-2301.
Yagi Y, Matono T, Nakamura K, Imura H. Postherpetic abdominal pseudohernia: A diagnostic pitfall. J Gen Fam Med. 2018 01; 19(1):36-37.
Kimura H, Ogawa Y, Fujimoto H, Mukai E, Kawashima H, Arimitsu K, Toyoda K, Fujita N, Yagi Y, Hamamatsu K, Murakami T, Murakami A, Ono M, Nakamoto Y, Togashi K, Inagaki N, Saji H. Evaluation of 18F-labeled exendin(9-39) derivatives targeting glucagon-like peptide-1 receptor for pancreatic ß-cell imaging. Bioorg Med Chem. 2018 01 15; 26(2):463-469.
Ishida N, Iizuka M, Kataoka K, Okazaki M, Shiraishi K, Yagi Y, Jobu K, Yokota J, Oishi M, Moriyama H, Shimamura T, Matsumura Y, Ukeda H, Miyamura M. Improvement of blood lipid profiles by Goishi tea polyphenols in a randomised, double-blind, placebo-controlled clinical study. Int J Food Sci Nutr. 2018 Aug; 69(5):598-607.
Kimura H, Fujita N, Kanbe K, Matsuda H, Watanabe H, Arimitsu K, Fujimoto H, Hamamatsu K, Yagi Y, Ono M, Inagaki N, Saji H. Synthesis and biological evaluation of an 111In-labeled exendin-4 derivative as a single-photon emission computed tomography probe for imaging pancreatic ß-cells. Bioorg Med Chem. 2017 10 15; 25(20):5772-5778.
Kurokawa Y, Sone H, Win-Shwe TT, Zeng Y, Kimura H, Koyama Y, Yagi Y, Matsui Y, Yamazaki M, Hirano S. Aggregation is a critical cause of poor transfer into the brain tissue of intravenously administered cationic PAMAM dendrimer nanoparticles. Int J Nanomedicine. 2017; 12:3967-3975.
Mori Y, Miyata K, Ono T, Yagi Y, Kamiya K, Amano S. Comparison of laser in situ ketatomileusis and photorefractive keratectomy for myopia using a mixed-effects model. PLoS One. 2017; 12(3):e0174810.
Kimura H, Okuda H, Ishiguro M, Arimitsu K, Makino A, Nishii R, Miyazaki A, Yagi Y, Watanabe H, Kawasaki I, Ono M, Saji H. 18F-Labeled Pyrido[3,4-d]pyrimidine as an Effective Probe for Imaging of L858R Mutant Epidermal Growth Factor Receptor. ACS Med Chem Lett. 2017 Apr 13; 8(4):418-422.
Kimura H, Matsuda H, Ogawa Y, Fujimoto H, Toyoda K, Fujita N, Arimitsu K, Hamamatsu K, Yagi Y, Ono M, Inagaki N, Saji H. Development of 111In-labeled exendin(9-39) derivatives for single-photon emission computed tomography imaging of insulinoma. Bioorg Med Chem. 2017 02 15; 25(4):1406-1412.
Arise K, Nishizaki S, Morita T, Yagi Y, Takeuchi S. Continued direct observation and feedback of hand hygiene adherence can result in long-term improvement. Am J Infect Control. 2016 11 01; 44(11):e211-e214.
Kimura H, Yagi Y, Arimitsu K, Maeda K, Ikejiri K, Takano JI, Kusuhara H, Kagawa S, Ono M, Sugiyama Y, Saji H. Radiosynthesis of novel pitavastatin derivative ([18 F]PTV-F1) as a tracer for hepatic OATP using a one-pot synthetic procedure. J Labelled Comp Radiopharm. 2016 11; 59(13):565-575.
Nakai M, Iizuka M, Matsui N, Hosogi K, Imai A, Abe N, Shiraishi H, Hirata A, Yagi Y, Jobu K, Yokota J, Kato E, Hosoda S, Yoshioka S, Harada K, Kubo M, Fukuyama Y, Miyamura M. Bangle (Zingiber purpureum) Improves Spatial Learning, Reduces Deficits in Memory, and Promotes Neurogenesis in the Dentate Gyrus of Senescence-Accelerated Mouse P8. J Med Food. 2016 May; 19(5):435-41.
Kobayashi T, Yagi Y, Nakamura T. Development of Genome Engineering Tools from Plant-Specific PPR Proteins Using Animal Cultured Cells. Methods Mol Biol. 2016; 1469:147-55.
Hirata A, Funato H, Nakai M, Iizuka M, Abe N, Yagi Y, Shiraishi H, Jobu K, Yokota J, Hirose K, Hyodo M, Miyamura M. Ginger Orally Disintegrating Tablets to Improve Swallowing in Older People. Biol Pharm Bull. 2016; 39(7):1107-11.
Abe N, Funato H, Hirata A, Nakai M, Iizuka M, Shiraishi H, Jobu K, Yagi Y, Kadota A, Ogi K, Yokota J, Miyamura M. [Evaluation of Gastric Mucosal Injury Model Animals of Rebamipide Formulation--Study of Therapeutic Equivalence]. Yakugaku Zasshi. 2016; 136(4):677-84.
Yagi Y, Kimura H, Arimitsu K, Ono M, Maeda K, Kusuhara H, Kajimoto T, Sugiyama Y, Saji H. The synthesis of [18F]pitavastatin as a tracer for hOATP using the Suzuki coupling. Org Biomol Chem. 2015 Jan 28; 13(4):1113-21.
Kimura H, Yagi Y, Ohneda N, Odajima H, Ono M, Saji H. Development of a resonant-type microwave reactor and its application to the synthesis of positron emission tomography radiopharmaceuticals. J Labelled Comp Radiopharm. 2014 Oct; 57(12):680-6.
Shiga T, Hase Y, Yagi Y, Takahashi N, Takechi K. Catalytic Cycle Employing a TEMPO-Anion Complex to Obtain a Secondary Mg-O2 Battery. J Phys Chem Lett. 2014 May 15; 5(10):1648-52.
Yagi Y, Okazaki M, Higaki H, Nakai M, Hirata A, Miyamura M. Outcome evaluation of an intervention to improve the effective and safe use of meropenem. Int J Clin Pharm. 2014 Jun; 36(3):648-56.
Yagi Y, Shiina T. Recent advances in the study of chloroplast gene expression and its evolution. Front Plant Sci. 2014; 5:61.
Yagi Y, Nakamura T, Small I. The potential for manipulating RNA with pentatricopeptide repeat proteins. Plant J. 2014 Jun; 78(5):772-82.
Kazama T, Yagi Y, Toriyama K, Nakamura T. Heterogeneity of the 5'-end in plant mRNA may be involved in mitochondrial translation. Front Plant Sci. 2013; 4:517.
Ichinose M, Sugita C, Yagi Y, Nakamura T, Sugita M. Two DYW subclass PPR proteins are involved in RNA editing of ccmFc and atp9 transcripts in the moss Physcomitrella patens: first complete set of PPR editing factors in plant mitochondria. Plant Cell Physiol. 2013 Nov; 54(11):1907-16.
Yagi Y, Tachikawa M, Noguchi H, Satoh S, Obokata J, Nakamura T. Pentatricopeptide repeat proteins involved in plant organellar RNA editing. RNA Biol. 2013; 10(9):1419-25.
Yagi Y, Hayashi S, Kobayashi K, Hirayama T, Nakamura T. Elucidation of the RNA recognition code for pentatricopeptide repeat proteins involved in organelle RNA editing in plants. PLoS One. 2013; 8(3):e57286.
Yamasaki K, Motomura Y, Yagi Y, Nomura H, Kikuchi S, Nakai M, Shiina T. Chloroplast envelope localization of EDS5, an essential factor for salicylic acid biosynthesis in Arabidopsis thaliana. Plant Signal Behav. 2013 Apr; 8(4):e23603.
Yagi Y, Shiina T. Evolutionary aspects of plastid proteins involved in transcription: the transcription of a tiny genome is mediated by a complicated machinery. Transcription. 2012 Nov-Dec; 3(6):290-4.
Murayama M, Hayashi S, Nishimura N, Ishide M, Kobayashi K, Yagi Y, Asami T, Nakamura T, Shinozaki K, Hirayama T. Isolation of Arabidopsis ahg11, a weak ABA hypersensitive mutant defective in nad4 RNA editing. J Exp Bot. 2012 Sep; 63(14):5301-10.
Nakamura T, Yagi Y, Kobayashi K. Mechanistic insight into pentatricopeptide repeat proteins as sequence-specific RNA-binding proteins for organellar RNAs in plants. Plant Cell Physiol. 2012 Jul; 53(7):1171-9.
Yagi Y, Ishizaki Y, Nakahira Y, Tozawa Y, Shiina T. Eukaryotic-type plastid nucleoid protein pTAC3 is essential for transcription by the bacterial-type plastid RNA polymerase. Proc Natl Acad Sci U S A. 2012 May 08; 109(19):7541-6.
Nakano T, Yagi Y, Miyahara M, Kaminura A, Kawatsura M, Itoh T. Chemo-enzymatic synthesis of a multi-useful chiral building block molecule for the synthesis of medicinal compounds. Molecules. 2011 Aug 09; 16(8):6747-57.
Onda Y, Yagi Y, Saito Y, Takenaka N, Toyoshima Y. Light induction of Arabidopsis SIG1 and SIG5 transcripts in mature leaves: differential roles of cryptochrome 1 and cryptochrome 2 and dual function of SIG5 in the recognition of plastid promoters. Plant J. 2008 Sep; 55(6):968-78.