Michael Hope, MD

Associate Professor
Chief of Radiology at the SFVAMC
Professor in Residence

Biography

Michael D. Hope, MD, is a Professor in Residence and Vice-Chair in the Department of Radiology and Biomedical Imaging at UCSF. He is Chief of Radiology at the San Francisco VA Health Care System (SFVAHCS). Dr. Hope obtained his medical degree from Stanford. He did a Medicine internship at California Pacific Medical Center, and then completed both his Diagnostic Radiology residency and fellowship in Cardiopulmonary Imaging at UCSF.

My principal research interest is studying the drivers of cardiovascular disease. My focus has been the application of advanced imaging techniques to better understand progressive aortic disease. These techniques include hemodynamic imaging with 4D Flow MRI, imaging of inflammation with a hybrid PET/MRI approach, and vessel lumen and wall imaging with novel MRI contrast agents. The overall goal is to target challenging and incompletely understood cardiovascular issues as detailed below, and use innovative imaging-derived analyses to better inform their clinical management.

Since assuming the role of Chief of Radiology at SFVAHCS in 2018, I have worked to organize, diversify and reinvigorate imaging research at the VA. We have established a new research leadership group called the VA Advanced Imaging Research Center (VAARC), which is intended to mirror the research structure of the UCSF Radiology Department and to clearly define responsibilities in a democratic leadership framework. The overarching goal is to promote teamwork as we strengthen and broaden our unique VA research program. We established a Steering Committee for VAARC that meets monthly and is composed of Directors for the 5 research domains (i.e., Neuro, CV, Body, AI and Informatics, Advanced Imaging), Key Investigators (M. Weiner) and the Chief of Radiology, who chairs the committee and facilitates discussion.

With our colleagues in Orthopedic Surgery at SFVAHCS, we established a VISN 21 Anatomic 3D Visualization/Printing Service in 2020 called Translational Radiology and Surgical Technologies, or TRST, that will provide 3D advanced visualization and printed to models of radiology exams to improve surgical planning for Veterans and concurrently improve resource utilization of VHA OR suites. This center will be based out of San Francisco. To develop this program, we have been granted FTE for two 3D technologists and a Biomedical Engineer, in addition to generous start up funds for hardware and software resources to enable routine 3D printing and/or visualization of cross-sectional studies, including capabilities for virtual and augmented reality.

Along with my colleague Travis Henry, I have taken on the issue of the judicious use of imaging during the COVID-19 pandemic. We have published in leading journals (Lancet, Annals of Internal Medicine) about the importance of careful and critical review of literature as we collectively better understand the role that CT may play in the management of COVID-19.

*Abnormal systolic blood flow with valve-related aortic disease.* My early cardiovascular research investigated hemodynamic alterations seen with aortic valve disease, a common clinical issue with relevance for up to 4% of people. Using 4D Flow MR imaging, I was the first to describe the helical systolic blood flow in the ascending thoracic aorta of patients with bicuspid aortic valves (BAV), and relate it to different aortic valve leaflet fusion patterns and the valve-related aortic disease seen in this population.

*Quantifying eccentric blood flow.* I hypothesized that the abnormal valve-related aortic flow we observed with BAV was directly related to asymmetrically elevated aortic wall shear stress, and as a consequence, that eccentric flow is associated with increased aortic growth rates. To better evaluate this, we explored a range of quantitative approaches to describe eccentric systolic blood flow and correlated them with growth.

*Advanced cardiovascular imaging with 4D Flow.* Our group at UCSF has pioneered the use of 4D Flow imaging for neurovascular and aortic evaluation. We have focused on practical, noninvasive clinical applications for challenging cardiovascular issues that may otherwise need invasive tests. We have expanded our investigation of hemodynamics with sequences that allow quantification of flow turbulence.

*Advanced aortic imaging.* I believe that a combined hemodynamic and inflammatory assessment using functional aortic imaging techniques will have the greatest impact in the evaluation of abdominal aortic aneurysms (AAA). We have explored new functional techniques including vessel wall strain analysis, inflammatory imaging, and combined PET/MRI. We seek to meaningfully advance the assessment of risk in patients who do not meet current intervention thresholds and improve outcomes by refining surveillance imaging regimens and decisions regarding early intervention for AAAs.

*Improved risk stratification of abdominal aortic aneurysm (AAA) disease.* Currently maximum aortic diameter is the principal metric used to manage AAA disease clinically, but this approach misses much of the complexity of the disease process, including intraluminal thrombus (ILT) and wall stress. We have focused on better defining the relationship between a range of anatomic and hemodynamic parameters and disease progression.

Education

Fellowship, 2010 - Cardiopulmonary Imaging, University of California, San Francisco
Residency, 2009 - Radiology, University of California, San Francisco
M.D., 2004 - School of Medicine, Stanford University

Honors and Awards

VA Merit Award, VA Office of Research and Development (ORD) Clinical Science Research and Development (CSR&D), 2020
Certificate of Excellence, San Francisco VA Health Care System, 2019
Outstanding Teacher Award, International Society for Magnetic Resonance in Medicine (ISMRM), 2017
Charles A. Dobry Visiting Professor, University of Nebraska Medical Center, 2017
Excellence in Teaching Award, Haile T. Debas Academy of Medical Educators, UCSF, 2015
R01 Grant, NIH/NHLBI, 2015
Distinguished Reviewer, Magnetic Resonance in Medicine, 2013
Research Scholar Grant, Radiological Society of North America (RSNA), 2012
1st Prize Young Investigator Award, North American Society for Cardiovascular Imaging (NASCI), 2009
1st Prize Bayer Poster Competition, North American Society for Cardiovascular Imaging (NASCI), 2008
Resident Research Grant, Radiological Society of North America (RSNA), 2008
Lauterbur Award Young Investigator Research Abstract Awards, Society of Computeed Body Tomography and Magnetic Resonance (SCBT/MR), 2004

Publications

Isikbay M, Henry TS, Frank JA, Hope MD. When to rule out COVID-19: How many negative RT-PCR tests are needed? Respir Med Case Rep. 2020; 31:101192.
Raptis CA, Hammer MM, Henry TS, Hope MD, Bhalla S. Reply to Letters Addressing "Chest CT and Coronavirus Disease (COVID-19): A Critical Review of the Literature to Date". AJR Am J Roentgenol. 2020 Jul 13; W1-W2.
Raptis CA, Hammer MM, Henry TS, Hope MD, Schiebler ML, van Beek EJR. What Do We Really Know About Pulmonary Thrombosis in COVID-19 Infection? J Thorac Imaging. 2020 Jun 29.
Adams HJA, Kwee TC, Yakar D, Hope MD, Kwee RM. Chest CT Imaging Signature of Coronavirus Disease 2019 Infection: In Pursuit of the Scientific Evidence. Chest. 2020 Jun 25.
Waller JV, Allen IE, Lin KK, Diaz MJ, Henry TS, Hope MD. The Limited Sensitivity of Chest Computed Tomography Relative to Reverse Transcription Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus-2 Infection: A Systematic Review on COVID-19 Diagnostics. Invest Radiol. 2020 Jun 16.
Adams HJA, Kwee TC, Yakar D, Hope MD, Kwee RM. Systematic Review and Meta-Analysis on the Value of Chest CT in the Diagnosis of Coronavirus Disease (COVID-19): Sol Scientiae, Illustra Nos. AJR Am J Roentgenol. 2020 Jun 01; 1-9.
Hammer MM, Raptis CA, Henry TS, Shah A, Bhalla S, Hope MD. Challenges in the interpretation and application of typical imaging features of COVID-19. Lancet Respir Med. 2020 06; 8(6):534-536.
Waller JV, Kaur P, Tucker A, Lin KK, Diaz MJ, Henry TS, Hope M. Diagnostic Tools for Coronavirus Disease (COVID-19): Comparing CT and RT-PCR Viral Nucleic Acid Testing. AJR Am J Roentgenol. 2020 10; 215(4):834-838.
van Hout MJ, Scholte AJ, Juffermans JF, Westenberg JJ, Zhong L, Zhou X, Schalla SM, Hope MD, Bremerich J, Kramer CM, Dewey M, Ordovas KG, Bluemke DA, Lamb HJ. How to Measure the Aorta Using MRI: A Practical Guide. J Magn Reson Imaging. 2020 Oct; 52(4):971-977.
Raptis CA, Hammer MM, Short RG, Shah A, Bhalla S, Bierhals AJ, Filev PD, Hope MD, Jeudy J, Kligerman SJ, Henry TS. Chest CT and Coronavirus Disease (COVID-19): A Critical Review of the Literature to Date. AJR Am J Roentgenol. 2020 10; 215(4):839-842.
Hope MD, Raptis CA, Henry TS. Chest Computed Tomography for Detection of Coronavirus Disease 2019 (COVID-19): Don't Rush the Science. Ann Intern Med. 2020 07 21; 173(2):147-148.
Hope MD, Raptis CA, Shah A, Hammer MM, Henry TS. A role for CT in COVID-19? What data really tell us so far. Lancet. 2020 04 11; 395(10231):1189-1190.
Ellis R, Ellestad E, Elicker B, Hope MD, Tosun D. Impact of hybrid supervision approaches on the performance of artificial intelligence for the classification of chest radiographs. Comput Biol Med. 2020 May; 120:103699.
Gomez A, Wang Z, Xuan Y, Wisneski AD, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng EE. Wall Stress Distribution in Bicuspid Aortic Valve-Associated Ascending Thoracic Aortic Aneurysms. Ann Thorac Surg. 2020 09; 110(3):807-814.
Wang Y, Zhu C, Leach J, Gasper W, Saloner D, Hope M. Growth of common iliac artery aneurysms coexisting with abdominal aortic aneurysms: associated factors and potential role of intraluminal thrombus. Quant Imaging Med Surg. 2020 Mar; 10(3):703-712.
Wang Z, Flores N, Lum M, Wisneski AD, Xuan Y, Inman J, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng EE. Wall stress analyses in patients with =5 cm versus <5 cm ascending thoracic aortic aneurysm. J Thorac Cardiovasc Surg. 2020 Feb 19.
Zhu C, Leach JR, Wang Y, Gasper W, Saloner D, Hope MD. Intraluminal Thrombus Predicts Rapid Growth of Abdominal Aortic Aneurysms. Radiology. 2020 03; 294(3):707-713.
Kallianos KG, Hope MD, Henry TS. Approach to Abnormal Chest Computed Tomography Contrast Enhancement in the Hospitalized Patient. Radiol Clin North Am. 2020 Jan; 58(1):93-103.
Garg P, Swift AJ, Zhong L, Carlhäll CJ, Ebbers T, Westenberg J, Hope MD, Bucciarelli-Ducci C, Bax JJ, Myerson SG. Assessment of mitral valve regurgitation by cardiovascular magnetic resonance imaging. Nat Rev Cardiol. 2020 05; 17(5):298-312.
Vella M, Meyer CS, Zhang N, Cohen BE, Whooley MA, Wang S, Hope MD. Association of Receipt of Positron Emission Tomography-Computed Tomography With Non-Small Cell Lung Cancer Mortality in the Veterans Affairs Health Care System. JAMA Netw Open. 2019 11 01; 2(11):e1915828.
Zhu C, Cao L, Wen Z, Ahn S, Raithel E, Forman C, Hope M, Saloner D. Surveillance of abdominal aortic aneurysm using accelerated 3D non-contrast black-blood cardiovascular magnetic resonance with compressed sensing (CS-DANTE-SPACE). J Cardiovasc Magn Reson. 2019 10 28; 21(1):66.
Nguyen KL, Yoshida T, Kathuria-Prakash N, Zaki IH, Varallyay CG, Semple SI, Saouaf R, Rigsby CK, Stoumpos S, Whitehead KK, Griffin LM, Saloner D, Hope MD, Prince MR, Fogel MA, Schiebler ML, Roditi GH, Radjenovic A, Newby DE, Neuwelt EA, Bashir MR, Hu P, Finn JP. Multicenter Safety and Practice for Off-Label Diagnostic Use of Ferumoxytol in MRI. Radiology. 2019 12; 293(3):554-564.
Mitsouras D, Hope MD. A Radiologist's Excursion in Four-dimensional Flow and the Bicuspid Aortic Valve: Vorticity, Helicity, Wall Shear Stress, and All That. Radiology. 2019 12; 293(3):551-553.
Leach J, Kao E, Zhu C, Saloner D, Hope MD. On the relative impact of intraluminal thrombus heterogeneity on abdominal aortic aneurysm mechanics. J Biomech Eng. 2019 Jun 29.
Zhu C, Leach JR, Tian B, Cao L, Wen Z, Wang Y, Liu X, Liu Q, Lu J, Saloner D, Hope MD. Evaluation of the distribution and progression of intraluminal thrombus in abdominal aortic aneurysms using high-resolution MRI. J Magn Reson Imaging. 2019 09; 50(3):994-1001.
Borger MA, Fedak PWM, Stephens EH, Gleason TG, Girdauskas E, Ikonomidis JS, Khoynezhad A, Siu SC, Verma S, Hope MD, Cameron DE, Hammer DF, Coselli JS, Moon MR, Sundt TM, Barker AJ, Markl M, Della Corte A, Michelena HI, Elefteriades JA. The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Executive summary. J Thorac Cardiovasc Surg. 2018 08; 156(2):473-480.
Borger MA, Fedak PWM, Stephens EH, Gleason TG, Girdauskas E, Ikonomidis JS, Khoynezhad A, Siu SC, Verma S, Hope MD, Cameron DE, Hammer DF, Coselli JS, Moon MR, Sundt TM, Barker AJ, Markl M, Della Corte A, Michelena HI, Elefteriades JA. The American Association for Thoracic Surgery consensus guidelines on bicuspid aortic valve-related aortopathy: Full online-only version. J Thorac Cardiovasc Surg. 2018 08; 156(2):e41-e74.
Burris NS, Patel HJ, Hope MD. Retrograde flow in the false lumen: Marker of a false lumen under stress? J Thorac Cardiovasc Surg. 2019 02; 157(2):488-491.
Merritt BA, Henry TS, Cha S, Ordovas KG, Kallianos KG, Elicker BM, Hope MD, Naeger DM. Tailoring Radiology Resident Education Using Aggregated Missed-Cases Data. J Am Coll Radiol. 2018 Jul; 15(7):1013-1015.
Zhu C, Kallianos K, Henry T, Hope MD. Ferumoxtyol-enhanced MR Angiography for Transcatheter Aortic Valve Replacement Planning in Patients with Renal Failure. Radiology. 2018 04; 287(1):362-363.
Zhu C, Saloner D, Hope MD. Letter by Zhu et al Regarding Article, "Aortic Wall Inflammation Predicts Abdominal Aortic Aneurysm Expansion, Rupture, and Need for Surgical Repair". Circulation. 2018 03 20; 137(12):1293-1294.
Xuan Y, Wang Z, Liu R, Haraldsson H, Hope MD, Saloner DA, Guccione JM, Ge L, Tseng E. Wall stress on ascending thoracic aortic aneurysms with bicuspid compared with tricuspid aortic valve. J Thorac Cardiovasc Surg. 2018 08; 156(2):492-500.
Burris NS, Lima APS, Hope MD, Ordovas KG. Feature Tracking Cardiac MRI Reveals Abnormalities in Ventricular Function in Patients With Bicuspid Aortic Valve and Preserved Ejection Fraction. Tomography. 2018 Mar; 4(1):26-32.
Zhu C, Haraldsson H, Kallianos K, Ge L, Tseng E, Henry T, Saloner D, Hope MD. Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast. Int J Cardiovasc Imaging. 2018 Mar; 34(3):475-483.
Mukai K, Burris NS, Mahadevan VS, Foster ED, Ordovas KG, Hope MD. 4D flow image quality with blood pool contrast: a comparison of gadofosveset trisodium and ferumoxytol. Int J Cardiovasc Imaging. 2018 Feb; 34(2):273-279.
Burris NS, Hope MD. Evolving treatment options for valve and aortic disease with bicuspid aortic valve. Ann Transl Med. 2017 Aug; 5(16):333.
Wang Y, Seguro F, Kao E, Zhang Y, Faraji F, Zhu C, Haraldsson H, Hope M, Saloner D, Liu J. Segmentation of lumen and outer wall of abdominal aortic aneurysms from 3D black-blood MRI with a registration based geodesic active contour model. Med Image Anal. 2017 Aug; 40:1-10.
Villanueva-Meyer JE, Naeger DM, Courtier JL, Hope MD, Lambert JW, MacKenzie JD, Phelps AS. Pediatric chest CT at chest radiograph doses: when is the ultralow-dose chest CT clinically appropriate? Emerg Radiol. 2017 Aug; 24(4):369-376.
Kallianos K, Henry TS, Yeghiazarians Y, Zimmet J, Shunk KA, Tseng EE, Mahadevan V, Hope MD. Ferumoxytol MRA for transcatheter aortic valve replacement planning with renal insufficiency. Int J Cardiol. 2017 Mar 15; 231:255-257.
Zhu C, Tian B, Leach JR, Liu Q, Lu J, Chen L, Saloner D, Hope MD. Non-contrast 3D black blood MRI for abdominal aortic aneurysm surveillance: comparison with CT angiography. Eur Radiol. 2017 May; 27(5):1787-1794.
Ge L, Haraldsson H, Hope MD, Saloner D, Guccione JM, Ratcliffe MB, Tseng EE. Suture Forces for Closure of Transapical Transcatheter Aortic Valve Replacement: A Mathematical Model. J Heart Valve Dis. 2016 07; 25(4):424-429.
Ordovas KG, Keedy A, Naeger DM, Kallianos K, Foster E, Liu J, Saloner D, Hope MD. Dilatation of the ascending aorta is associated with presence of aortic regurgitation in patients after repair of tetralogy of Fallot. Int J Cardiovasc Imaging. 2016 Aug; 32(8):1265-72.
Burris NS, Dyverfeldt P, Hope MD. Ascending Aortic Stiffness with Bicuspid Aortic Valve is Variable and Not Predicted by Conventional Parameters in Young Patients. J Heart Valve Dis. 2016 05; 25(3):270-280.
Vasanawala SS, Nguyen KL, Hope MD, Bridges MD, Hope TA, Reeder SB, Bashir MR. Safety and technique of ferumoxytol administration for MRI. Magn Reson Med. 2016 May; 75(5):2107-11.
Wisneski AD, Mookhoek A, Chitsaz S, Hope MD, Guccione JM, Ge L, Tseng EE. Bicuspid Aortic Valve-Associated Ascending Thoracic Aortic Aneurysm: Patient-Specific Finite Element Analysis. J Heart Valve Dis. 2015 Nov; 24(6):714-721.
Conrad MB, Ishaque BM, Surman AM, Kerlan RK, Hope MD, Dickey MA, Hetts SW, Wilson MW. Intraprocedural Safety and Technical Success of the MVP Micro Vascular Plug for Embolization of Pulmonary Arteriovenous Malformations. J Vasc Interv Radiol. 2015 Nov; 26(11):1735-9.
Zhu C, Haraldsson H, Faraji F, Owens C, Gasper W, Ahn S, Liu J, Laub G, Hope MD, Saloner D. Isotropic 3D black blood MRI of abdominal aortic aneurysm wall and intraluminal thrombus. Magn Reson Imaging. 2016 Jan; 34(1):18-25.
Kathiria NN, Devcic Z, Chen JS, Naeger DM, Hope MD, Higgins CB, Ordovas KG. Assessment of Left Ventricular Enlargement at Multidetector Computed Tomography. J Comput Assist Tomogr. 2015 Sep-Oct; 39(5):794-6.
Dyverfeldt P, Bissell M, Barker AJ, Bolger AF, Carlhäll CJ, Ebbers T, Francios CJ, Frydrychowicz A, Geiger J, Giese D, Hope MD, Kilner PJ, Kozerke S, Myerson S, Neubauer S, Wieben O, Markl M. 4D flow cardiovascular magnetic resonance consensus statement. J Cardiovasc Magn Reson. 2015 Aug 10; 17:72.
Krishnan K, Ge L, Haraldsson H, Hope MD, Saloner DA, Guccione JM, Tseng EE. Ascending thoracic aortic aneurysm wall stress analysis using patient-specific finite element modeling of in vivo magnetic resonance imaging. Interact Cardiovasc Thorac Surg. 2015 Oct; 21(4):471-80.
Burris NS, Johnson KM, Larson PE, Hope MD, Nagle SK, Behr SC, Hope TA. Detection of Small Pulmonary Nodules with Ultrashort Echo Time Sequences in Oncology Patients by Using a PET/MR System. Radiology. 2016 Jan; 278(1):239-46.
Hope MD, Hope TA, Zhu C, Faraji F, Haraldsson H, Ordovas KG, Saloner D. Vascular Imaging With Ferumoxytol as a Contrast Agent. AJR Am J Roentgenol. 2015 Sep; 205(3):W366-73.
Hope MD, Gasper WJ, Rapp J, Owens CD, Haraldsson H, Saloner D. Vascular inflammation in a growing iliac artery aneurysm. Clin Nucl Med. 2015 Jun; 40(6):e323-4.
Sohrabi S, Hope M, Saloner D, Keedy A, Naeger D, Lorca MC, Ordovas KG. Left atrial transverse diameter on computed tomography angiography can accurately diagnose left atrial enlargement in patients with atrial fibrillation. J Thorac Imaging. 2015 May; 30(3):214-7.
Burris NS, Hope MD. Bicuspid valve-related aortic disease: flow assessment with conventional phase-contrast MRI. Acad Radiol. 2015 Jun; 22(6):690-6.
Sigovan M, Dyverfeldt P, Wrenn J, Tseng EE, Saloner D, Hope MD. Extended 3D approach for quantification of abnormal ascending aortic flow. Magn Reson Imaging. 2015 Jun; 33(5):695-700.
Kari FA, Kocher N, Beyersdorf F, Tscheuschler A, Meffert P, Rylski B, Siepe M, Russe MF, Hope MD. Four-dimensional magnetic resonance imaging-derived ascending aortic flow eccentricity and flow compression are linked to aneurysm morphology†. Interact Cardiovasc Thorac Surg. 2015 May; 20(5):582-7; discussion 587-8.
Benedetti N, Hope MD. Prevalence and significance of incidentally noted dilation of the ascending aorta on routine chest computed tomography in older patients. J Comput Assist Tomogr. 2015 Jan-Feb; 39(1):109-11.
Hope MD, Sigovan M, Dyverfeldt P. Letter by Hope et al regarding article, "Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy". Circulation. 2014 Nov 04; 130(19):e170.
Wisneski AD, Mookhoek A, Chitsaz S, Hope MD, Guccione JM, Ge L, Tseng EE. Patient-specific finite element analysis of ascending thoracic aortic aneurysm. J Heart Valve Dis. 2014 Nov; 23(6):765-72.
Burris NS, Hope MD. 4D flow MRI applications for aortic disease. Magn Reson Imaging Clin N Am. 2015 Feb; 23(1):15-23.
Velez E, Boyer N, Acevedo-Bolton G, Hope MD, Boyle A. CT-reconstructed three-dimensional printed models of the right subclavian artery and aorta define age-related changes and facilitate benchtop catheter testing. J Invasive Cardiol. 2014 Oct; 26(10):E141-4.
Burris NS, Sigovan M, Knauer HA, Tseng EE, Saloner D, Hope MD. Systolic flow displacement correlates with future ascending aortic growth in patients with bicuspid aortic valves undergoing magnetic resonance surveillance. Invest Radiol. 2014 Oct; 49(10):635-9.
Dusch MN, Thadani SR, Dhillon GS, Hope MD. Diastolic function assessed by cardiac MRI using longitudinal left ventricular fractional shortening. Clin Imaging. 2014 Sep-Oct; 38(5):666-8.
Thadani SR, Dyverfeldt P, Gin A, Chitsaz S, Rao RK, Hope MD. Comprehensive evaluation of culture-negative endocarditis with use of cardiac and 4-dimensional-flow magnetic resonance imaging. Tex Heart Inst J. 2014 Jun; 41(3):351-2.
Liu J, Dyverfeldt P, Acevedo-Bolton G, Hope M, Saloner D. Highly accelerated aortic 4D flow MR imaging with variable-density random undersampling. Magn Reson Imaging. 2014 Oct; 32(8):1012-20.
Haraldsson H, Hope M, Acevedo-Bolton G, Tseng E, Zhong X, Epstein FH, Ge L, Saloner D. Feasibility of asymmetric stretch assessment in the ascending aortic wall with DENSE cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2014 Jan 09; 16:6.
Hope MD, Hope TA. Functional and molecular imaging techniques in aortic aneurysm disease. Curr Opin Cardiol. 2013 Nov; 28(6):609-18.
Hope MD, Sigovan M, Wrenn SJ, Saloner D, Dyverfeldt P. MRI hemodynamic markers of progressive bicuspid aortic valve-related aortic disease. J Magn Reson Imaging. 2014 Jul; 40(1):140-5.
Hope MD, Sedlic T, Dyverfeldt P. Cardiothoracic magnetic resonance flow imaging. J Thorac Imaging. 2013 Jul; 28(4):217-30.
Ordovas KG, Muzzarelli S, Hope MD, Naeger DM, Karl T, Reddy GP, Marchiori E, Higgins CB. Cardiovascular MR imaging after surgical correction of tetralogy of Fallot: approach based on understanding of surgical procedures. Radiographics. 2013 Jul-Aug; 33(4):1037-52.
Azadani AN, Chitsaz S, Mannion A, Mookhoek A, Wisneski A, Guccione JM, Hope MD, Ge L, Tseng EE. Biomechanical properties of human ascending thoracic aortic aneurysms. Ann Thorac Surg. 2013 Jul; 96(1):50-8.
Hope TA, Kvitting JP, Hope MD, Miller DC, Markl M, Herfkens RJ. Evaluation of Marfan patients status post valve-sparing aortic root replacement with 4D flow. Magn Reson Imaging. 2013 Nov; 31(9):1479-84.
Hope MD, Wrenn SJ, Dyverfeldt P. Clinical Applications of Aortic 4D Flow Imaging. Curr Cardiovasc Imaging Rep. 2013; 6(2):128-39.
Dyverfeldt P, Hope MD, Tseng EE, Saloner D. Magnetic resonance measurement of turbulent kinetic energy for the estimation of irreversible pressure loss in aortic stenosis. JACC Cardiovasc Imaging. 2013 Jan; 6(1):64-71.
Markl M, Frydrychowicz A, Kozerke S, Hope M, Wieben O. 4D flow MRI. J Magn Reson Imaging. 2012 Nov; 36(5):1015-36.
Lu MT, Thadani SR, Hope MD. Quantitative assessment of asymmetric aortic dilation with valve-related aortic disease. Acad Radiol. 2013 Jan; 20(1):10-5.
Hope MD, Wrenn J, Sigovan M, Foster E, Tseng EE, Saloner D. Imaging biomarkers of aortic disease: increased growth rates with eccentric systolic flow. J Am Coll Cardiol. 2012 Jul 24; 60(4):356-7.
Yildiz S, Boyaci N, Karakas O, Karakas E, Cece H. Re: bovine aortic arch: a novel association with thoracic aortic dilation. Clin Radiol. 2012 Jun; 67(6):618; author reply 618.
Chitsaz S, Gundiah N, Blackshear C, Tegegn N, Yan KS, Azadani AN, Hope M, Tseng EE. Correlation of calcification on excised aortic valves by micro-computed tomography with severity of aortic stenosis. J Heart Valve Dis. 2012 May; 21(3):320-7.
Cannavale G, Hope MD, Crook SE, Elicker BM. Dynamic evaluation of a quadricuspid aortic valve with coronary computed tomography angiography. J Thorac Imaging. 2012 May; 27(3):W46-7.
Mallik M, Callaghan CJ, Hope M, Gibbs P, Davies S, Gimson AE, Griffiths WJ, Pettigrew GJ. Comparison of liver transplantation outcomes from adult split liver and circulatory death donors. Br J Surg. 2012 Jun; 99(6):839-47.
Hope TA, Hope MD. Improved risk assessment for abdominal aortic aneurysm rupture: off-the-wall imaging. J Am Coll Cardiol. 2011 Dec 06; 58(24):2531-2.
Hope MD, Urbania TH, Yu JP, Chitsaz S, Tseng E. Incidental aortic valve calcification on CT scans: significance for bicuspid and tricuspid valve disease. Acad Radiol. 2012 May; 19(5):542-7.
Malone CD, Urbania TH, Crook SE, Hope MD. Bovine aortic arch: a novel association with thoracic aortic dilation. Clin Radiol. 2012 Jan; 67(1):28-31.
Ordovas KG, Carlsson M, Lease KE, Foster E, Meadows AK, Martin AJ, Hope M, Do L, Higgins CB, Saeed M. Impaired regional left ventricular strain after repair of tetralogy of Fallot. J Magn Reson Imaging. 2012 Jan; 35(1):79-85.
Sigovan M, Hope MD, Dyverfeldt P, Saloner D. Comparison of four-dimensional flow parameters for quantification of flow eccentricity in the ascending aorta. J Magn Reson Imaging. 2011 Nov; 34(5):1226-30.
Hope MD, Dyverfeldt P, Acevedo-Bolton G, Wrenn J, Foster E, Tseng E, Saloner D. Post-stenotic dilation: evaluation of ascending aortic dilation with 4D flow MR imaging. Int J Cardiol. 2012 Apr 19; 156(2):e40-2.
Muzzarelli S, Meadows AK, Ordovas KG, Hope MD, Higgins CB, Nielsen JC, Geva T, Meadows JJ. Prediction of hemodynamic severity of coarctation by magnetic resonance imaging. Am J Cardiol. 2011 Nov 01; 108(9):1335-40.
Hope MD, Hope TA, Crook SE, Ordovas KG, Urbania TH, Alley MT, Higgins CB. 4D flow CMR in assessment of valve-related ascending aortic disease. JACC Cardiovasc Imaging. 2011 Jul; 4(7):781-7.
Crook SE, Hope MD. Arch hypoplasia and aneurysm after aortic coarctation repair: abnormal flow may be the link. JACC Cardiovasc Imaging. 2011 Jun; 4(6):685-6.
Muzzarelli S, Ordovas KG, Hope MD, Meadows JJ, Higgins CB, Meadows AK. Diagnostic value of the flow profile in the distal descending aorta by phase-contrast magnetic resonance for predicting severe coarctation of the aorta. J Magn Reson Imaging. 2011 Jun; 33(6):1440-6.
Bogren HG, Buonocore MH. Helical-shaped streamlines do not represent helical flow. Radiology. 2010 Dec; 257(3):895-6; author reply 896.
Hope MD, Hope TA, Urbania TH, Higgins CB. Four-dimensional flow magnetic resonance imaging with wall shear stress analysis before and after repair of aortopulmonary fistula. Circ Cardiovasc Imaging. 2010 Nov; 3(6):766-8.
Girdauskas E, Borger MA, Kuntze T, Hope MD. Aortopathy in bicuspid aortic valve disease: is it really congenital? Radiology. 2010 Sep; 256(3):1015-6; author reply 1016.
Hope MD, Hope TA, Meadows AK, Ordovas KG, Urbania TH, Alley MT, Higgins CB. Bicuspid aortic valve: four-dimensional MR evaluation of ascending aortic systolic flow patterns. Radiology. 2010 Apr; 255(1):53-61.
Hope MD, Meadows AK, Hope TA, Ordovas KG, Saloner D, Reddy GP, Alley MT, Higgins CB. Clinical evaluation of aortic coarctation with 4D flow MR imaging. J Magn Reson Imaging. 2010 Mar; 31(3):711-8.
Hope TA, Hope MD, Purcell DD, von Morze C, Vigneron DB, Alley MT, Dillon WP. Evaluation of intracranial stenoses and aneurysms with accelerated 4D flow. Magn Reson Imaging. 2010 Jan; 28(1):41-6.
Urbania TH, Hope MD, Huffaker SD, Reddy GP. Role of computed tomography in the evaluation of acute chest pain. J Cardiovasc Comput Tomogr. 2009 Jan-Feb; 3(1 Suppl):S13-22.
Hope MD, Purcell DD, Hope TA, von Morze C, Vigneron DB, Alley MT, Dillon WP. Complete intracranial arterial and venous blood flow evaluation with 4D flow MR imaging. AJNR Am J Neuroradiol. 2009 Feb; 30(2):362-6.
Hope MD, Meadows AK, Hope TA, Ordovas KG, Reddy GP, Alley MT, Higgins CB. Images in cardiovascular medicine. Evaluation of bicuspid aortic valve and aortic coarctation with 4D flow magnetic resonance imaging. Circulation. 2008 May 27; 117(21):2818-9.
Markl M, Draney MT, Hope MD, Levin JM, Chan FP, Alley MT, Pelc NJ, Herfkens RJ. Time-resolved 3-dimensional velocity mapping in the thoracic aorta: visualization of 3-directional blood flow patterns in healthy volunteers and patients. J Comput Assist Tomogr. 2004 Jul-Aug; 28(4):459-68.
Hope MD, Levin JM, Markl M, Draney MT, Alley M, Herfkens RJ. Images in cardiovascular medicine. Four-dimensional magnetic resonance velocity mapping in a healthy volunteer with pseudocoarctation of the thoracic aorta. Circulation. 2004 Jun 29; 109(25):3221-2.
Hope MD. Everyday amnesia. The curious effects of a common drug. Pharos Alpha Omega Alpha Honor Med Soc. 2004; 67(1):18-21.
Hope MD, de la Pena E, Yang PC, Liang DH, McConnell MV, Rosenthal DN. A visual approach for the accurate determination of echocardiographic left ventricular ejection fraction by medical students. J Am Soc Echocardiogr. 2003 Aug; 16(8):824-31.
Hope MD. MSJAMA. Pain and forgetting. JAMA. 2003 Feb 05; 289(5):617.
Pravenec M, Kren V, Hope M, Wang JM, St Lezin E. Linkage mapping of the interleukin 1beta converting enzyme (Il1bc) and the glutamate receptor subunit KA1 (Grik4) genes to rat chromosome 8. Folia Biol (Praha). 1998; 44(3):107-9.