Matthew Bucknor, MD

Associate Professor
Associate Chair, Wellbeing and Professional Climate
Chair, Diversity Committee
Co-Director of Focused Ultrasound
Associate Professor In Res.

Biography

Matthew Bucknor, MD, is an Associate Professor in Residence in the Musculoskeletal Imaging subspecialty section, and the Inaugural Associate Chair for Wellbeing and Professional Climate in the UCSF Department of Radiology and Biomedical Imaging. He is also the Chair of the Radiology and Biomedical Imaging Diversity Committee in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He received his medical degree from Stanford School of Medicine and his four-year residency in Diagnostic Radiology at UCSF, followed by a clinical fellowship in Musculoskeletal Imaging and Intervention at Stanford Medical Center. After completing his fellowship, Dr. Bucknor joined the Musculoskeletal Imaging faculty as an Assistant Professor in Residence at UCSF.

Dr. Bucknor’s main research interest is developing new musculoskeletal applications of MR-guided high intensity focused ultrasound (MRgHIFU), including new treatments of bone metastases, desmoid tumors, and osteoid osteomas. He is also interested in minimally invasive interventions as well as novel techniques for evaluating bone/soft tissue tumors, along with arthropathies, and sports injuries.

Dr. Bucknor has published 30 peer-reviewed articles, including 12 first author publications.

Expertise:
Musculoskeletal Radiology

Specialty:
MR-guided high intensity focused ultrasound and minimally invasive interventions

Professional Interests:
MR-guided high intensity focused ultrasound, minimally invasive interventions, cartilage imaging, and musculoskeletal applications of PET/MR

Education and Training:
• Medical School: Stanford School of Medicine, Stanford, CA
• Internship: Kaiser Permanente, San Francisco, CA - Preliminary Internal Medicine
• Residency: University of California, San Francisco
• Fellowship: Stanford University, Stanford, CA – Musculoskeletal Imaging and Intervention

Education

2017 - Diversity, Equity, and Inclusion Champion Training, University of California
Residency, 2013 - School of Medicine - Radiology, University of California, San Francisco
M.D., 2008 - , Stanford School of Medicine
B.A., 2003 - , Harvard College

Honors and Awards

Andrew J. Lockhart Memorial Prize, Focused Ultrasound Foundation, 2020
Chancellor Award for Dr. Martin Luther King Jr. Leadership, UCSF, 2019
John A. Watson Faculty Scholar, UCSF, 2015
Trainee Research Prize, RSNA, 2013
Resident-in-Training Scholarship, Society of Interventional Radiology, 2011

Publications

Bucknor MD, Hope T. Reply: "Disparities in PET imaging for prostate cancer at a tertiary academic medical center". J Nucl Med. 2021 Mar 19.
Bruno Astuto, Io Flament, Nikan K. Namiri, Rutwik Shah, Upasana Bharadwaj, Thomas M. Link, Matthew D. Bucknor, Valentina Pedoia, Sharmila Majumdar. Automatic Deep Learning Assisted Detection and Grading of Abnormalities in Knee MRI Studies. Radiology Artificial Intelligence. 2021 Jan 20; e200165.
Zhang W, Trivedi H, Adams M, Losey AD, Diederich CJ, Ozhinsky E, Rieke V, Bucknor MD. Anatomic thermochromic tissue-mimicking phantom of the lumbar spine for pre-clinical evaluation of MR-guided focused ultrasound (MRgFUS) ablation of the facet joint. Int J Hyperthermia. 2021; 38(1):130-135.
Warnert EAH, Kasper L, Meltzer CC, Lightfoote JB, Bucknor MD, Haroon H, Duggan G, Gowland P, Wald L, Miller KL, Morris EA, Anazodo UC. Resonate: Reaching Excellence Through Equity, Diversity, and Inclusion in ISMRM. J Magn Reson Imaging. 2020 Dec 21.
Bucknor MD, Chan FP, Matuoka JY, Curl PK, Kahn JG. Cost-effectiveness analysis of magnetic resonance-guided focused ultrasound ablation for palliation of refractory painful bone metastases. Int J Technol Assess Health Care. 2020 Dec 03; 1-7.
Borno HT, Kuo Lin T, Odisho AY, Desai A, Koshkin V, Werner K, Legaspi N, Bucknor M, Bell A, Zhang S, Hope TA. Evaluating determinants of receipt of molecular imaging in biochemical recurrent prostate cancer. Cancer Med. 2020 Nov 28.
Smith SE, Chang EY, Ha AS, Bartolotta RJ, Bucknor M, Chandra T, Chen KC, Gorbachova T, Khurana B, Klitzke AK, Lee KS, Mooar PA, Ross AB, Shih RD, Singer AD, Taljanovic MS, Thomas JM, Tynus KM, Kransdorf MJ. ACR Appropriateness Criteria® Acute Trauma to the Ankle. J Am Coll Radiol. 2020 Nov; 17(11S):S355-S366.
Radhika Tibrewala, Valentina Pedoia, Matthew Bucknor, Sharmila Majumdar. Principal Component Analysis of Simultaneous PET-MRI Reveals Patterns of Bone–Cartilage Interactions in Osteoarthritis. Journal of Magnetic Resonance Imaging. 2020 Nov 1; 52(5).
Bucknor MD, Lichtensztajn DY, Lin TK, Borno HT, Gomez SL, Hope TA. Disparities in PET imaging for prostate cancer at a tertiary academic medical center. J Nucl Med. 2020 Sep 25.
Ramezanpour S, Horvai AE, Zimel M, Bucknor M, Link TM. Fibroma-like perivascular epithelioid cell tumor: a rare case in a long bone. Skeletal Radiol. 2020 Sep 18.
Glastonbury CM, Bucknor M, Wall SD, Hess CP. Hiring Through the Lens of Diversity: Strategies to Create Diverse Departments. Acad Radiol. 2020 Aug 27.
Taljanovic MS, Chang EY, Ha AS, Bartolotta RJ, Bucknor M, Chen KC, Gorbachova T, Khurana B, Klitzke AK, Lee KS, Mooar PA, Nguyen JC, Ross AB, Shih RD, Singer AD, Smith SE, Thomas JM, Yost WJ, Kransdorf MJ. ACR Appropriateness Criteria® Acute Trauma to the Knee. J Am Coll Radiol. 2020 May; 17(5S):S12-S25.
Chiu LW, Lawhn-Heath C, Behr SC, Juarez R, Perez PM, Lobach I, Bucknor MD, Hope TA, Flavell RR. Factors Predicting Metastatic Disease in 68Ga-PSMA-11 PET-Positive Osseous Lesions in Prostate Cancer. J Nucl Med. 2020 Dec; 61(12):1779-1785.
Tibrewala R, Pedoia V, Bucknor M, Majumdar S. Principal Component Analysis of Simultaneous PET-MRI Reveals Patterns of Bone-Cartilage Interactions in Osteoarthritis. J Magn Reson Imaging. 2020 11; 52(5):1462-1474.
Webb EM, Kallianos KG, Vella M, Straus CM, Bucknor MD, Galvan J, Scoutt LM. Are Women Disproportionately Represented in Education Compared to Other Roles in Academic Radiology? Acad Radiol. 2020 12; 27(12):1767-1773.
Schirò S, Foreman SC, Bucknor M, Chin CT, Joseph GB, Link TM. Diagnostic Performance of CT-Guided Bone Biopsies in Patients with Suspected Osteomyelitis of the Appendicular and Axial Skeleton with a Focus on Clinical and Technical Factors Associated with Positive Microbiology Culture Results. J Vasc Interv Radiol. 2020 Mar; 31(3):464-472.
Bucknor MD, Villanueva-Meyer JE, Kumar V, Talbott JF, Wall SD, Glastonbury CM, Dillon WP, Arenson RL, Wilson MW, Hess CP. Diversity and Inclusion Efforts in University of California, San Francisco Radiology: Reflections on 3 Years of Pipeline, Selection, and Education Initiatives. J Am Coll Radiol. 2019 Dec; 16(12):1716-1719.
Kallianos KG, Webb EM, Hess CP, Talbott J, Bucknor MD. Use of the Implicit Association Test to Improve Diversity in Radiology. J Am Coll Radiol. 2019 Jul; 16(7):976-979.
B. Astuto Arouche Nunes, I. Flament, R. Shah, M. Bucknor, T. Link, V. Pedoia, S. Majumdar. MRI-based multi-task deep learning for cartilage lesion severity staging in knee osteoarthritis. Osteoarthritis and Cartilage. 2019 Apr 1; 27:s398-s399.
L. Chen, R. Shah, T. Link, M. Bucknor, S. Majumdar, V. Pedoia. Text sentiment analysis for cartilage abnormalities detection from radiology reports. Osteoarthritis and Cartilage. 2019 Apr 1; 27:s400-s401.
Bucknor MD, Beroukhim G, Rieke V, Ozhinsky E, Lobach I. The impact of technical parameters on ablation volume during MR-guided focused ultrasound of desmoid tumors. Int J Hyperthermia. 2019; 36(1):473-476.
Beroukhim G, Shah R, Bucknor MD. Factors Predicting Positive Culture in CT-Guided Bone Biopsy Performed for Suspected Osteomyelitis. AJR Am J Roentgenol. 2019 03; 212(3):620-624.
Morochnik S, Ozhinsky E, Rieke V, Bucknor MD. T2 mapping as a predictor of nonperfused volume in MRgFUS treatment of desmoid tumors. Int J Hyperthermia. 2019; 36(1):1272-1277.
Lee AY, Navarro R, Busby LP, Greenwood HI, Bucknor MD, Ray KM, Joe BN. Characterization of Metastatic Sternal Lesions on Dynamic Contrast-Enhanced Breast MRI in Women with Invasive Breast Cancer. Acad Radiol. 2019 10; 26(10):1358-1362.
Bucknor MD, Goel H, Pasco C, Horvai AE, Kazakia GJ. Bone remodeling following MR-guided focused ultrasound: Evaluation with HR-pQCT and FTIR. Bone. 2019 03; 120:347-353.
Pedoia V, Norman B, Mehany SN, Bucknor MD, Link TM, Majumdar S. 3D convolutional neural networks for detection and severity staging of meniscus and PFJ cartilage morphological degenerative changes in osteoarthritis and anterior cruciate ligament subjects. J Magn Reson Imaging. 2019 02; 49(2):400-410.
M. Bucknor, J. Matuoka, F. Chan, S.R. Secoli, J. Kahn. PMD81 - COST EFFECTIVENESS ANALYSIS OF MAGNETIC RESONANCE-GUIDED FOCUSED ULTRASOUND FOR REFRACTORY PAINFUL BONE METASTASES. Value in Health. 2018 Oct 1; 21:s257.
Webb EM, Bucknor MD, Naeger DM. Diversity and Inclusion: Now Radiology Must Walk the Walk. J Am Coll Radiol. 2018 04; 15(4):687-688.
Guimaraes JB, Nevitt MC, McCulloch CE, Schwaiger BJ, Gersing AS, Facchetti L, Bucknor MD, Chanchek N, Liu F, Joseph GB, Link TM. Association of weight change with progression of meniscal intrasubstance degeneration over 48 months: Data from the Osteoarthritis Initiative. Eur Radiol. 2018 Mar; 28(3):953-962.
Varenika V, Lutz AM, Beaulieu CF, Bucknor MD. Detection and prevalence of variant sciatic nerve anatomy in relation to the piriformis muscle on MRI. Skeletal Radiol. 2017 Jun; 46(6):751-757.
Jafri K, Zahed H, Wysham KD, Patterson S, Nolan AL, Bucknor MD, Chaganti RK. Antimalarial myopathy in a systemic lupus erythematosus patient with quadriparesis and seizures: a case-based review. Clin Rheumatol. 2017 Jun; 36(6):1437-1444.
Bucknor MD, Ozhinsky E, Shah R, Krug R, Rieke V. Effect of Sonication Duration and Power on Ablation Depth During MR-Guided Focused Ultrasound of Bone. J Magn Reson Imaging. 2017 11; 46(5):1418-1422.
Bucknor MD, Rieke V. MRgFUS for desmoid tumors within the thigh: early clinical experiences. J Ther Ultrasound. 2017; 5:4.
Ozhinsky E, Han M, Bucknor M, Krug R, Rieke V. T2-based temperature monitoring in bone marrow for MR-guided focused ultrasound. J Ther Ultrasound. 2016; 4:26.
Bucknor MD, Stevens KJ, Steinbach LS. Elbow Imaging in Sport: Sports Imaging Series. Radiology. 2016 07; 280(1):328.
Temple MJ, Waspe AC, Amaral JG, Napoli A, LeBlang S, Ghanouni P, Bucknor MD, Campbell F, Drake JM. Establishing a clinical service for the treatment of osteoid osteoma using magnetic resonance-guided focused ultrasound: overview and guidelines. J Ther Ultrasound. 2016; 4:16.
Ghanouni P, Dobrotwir A, Bazzocchi A, Bucknor M, Bitton R, Rosenberg J, Telischak K, Busacca M, Ferrari S, Albisinni U, Walters S, Gold G, Ganjoo K, Napoli A, Pauly KB, Avedian R. Magnetic resonance-guided focused ultrasound treatment of extra-abdominal desmoid tumors: a retrospective multicenter study. Eur Radiol. 2017 Feb; 27(2):732-740.
Bucknor MD, Stevens KJ, Steinbach LS. Elbow Imaging in Sport: Sports Imaging Series. Radiology. 2016 Apr; 279(1):12-28.
Savic D, Pedoia V, Seo Y, Yang J, Bucknor M, Franc BL, Majumdar S. Imaging Bone-Cartilage Interactions in Osteoarthritis Using [18F]-NaF PET-MRI. Mol Imaging. 2016 01 01; 15:1-12.
Pejman Ghanouni, Kim Butts Pauly, Rachelle Bitton, Raffi Avedian, Matthew Bucknor, Garry Gold. MR guided focused ultrasound treatment of soft tissue tumors of the extremities — preliminary experience. Journal of Therapeutic Ultrasound. 2015 Dec 1; 3(Suppl 1):o69.
Bucknor MD, Nardo L, Joseph GB, Alizai H, Srikhum W, Nevitt MC, Lynch JA, McCulloch CE, Link TM. Association of cartilage degeneration with four year weight gain--3T MRI data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2015 Apr; 23(4):525-31.
Bucknor MD, Rieke V, Seo Y, Horvai AE, Hawkins RA, Majumdar S, Link TM, Saeed M. Bone remodeling after MR imaging-guided high-intensity focused ultrasound ablation: evaluation with MR imaging, CT, Na(18)F-PET, and histopathologic examination in a swine model. Radiology. 2015 Feb; 274(2):387-94.
Bucknor MD, Steinbach LS, Saloner D, Chin CT. Magnetic resonance neurography evaluation of chronic extraspinal sciatica after remote proximal hamstring injury: a preliminary retrospective analysis. J Neurosurg. 2014 Aug; 121(2):408-14.
Bucknor MD, Rieke V, Do L, Majumdar S, Link TM, Saeed M. MRI-guided high-intensity focused ultrasound ablation of bone: evaluation of acute findings with MR and CT imaging in a swine model. J Magn Reson Imaging. 2014 Nov; 40(5):1174-80.
Bucknor MD, Goo JS, Coppolino ML. The risk of potential thromboembolic, renal and cardiac complications of sickle cell trait. Hemoglobin. 2014; 38(1):28-32.
Bucknor MD, Gross AJ, Link TM. Voriconazole-induced periostitis in two post-transplant patients. J Radiol Case Rep. 2013 Aug; 7(8):10-7.
Coakley FV, Hanley-Knutson K, Mongan J, Barajas R, Bucknor M, Qayyum A. Pancreatic imaging mimics: part 1, imaging mimics of pancreatic adenocarcinoma. AJR Am J Roentgenol. 2012 Aug; 199(2):301-8.
Maythem Saeed, Alastair Martin, Loi Do, Matthew Bucknor, David Saloner, Charles Higgins. 309 MR assessment of myocardial perfusion, viability and function after intramyocardial transfer of plasmid expressing two isoforms of hepatocyte growth factor in swine model. Critical Reviews in Computed Tomography. 2008 Oct 1; 10(Suppl 1):a112.
Saeed M, Martin A, Jacquier A, Bucknor M, Saloner D, Do L, Ursell P, Su H, Kan YW, Higgins CB. Permanent coronary artery occlusion: cardiovascular MR imaging is platform for percutaneous transendocardial delivery and assessment of gene therapy in canine model. Radiology. 2008 Nov; 249(2):560-71.
Saeed M, Martin A, Ursell P, Do L, Bucknor M, Higgins CB, Saloner D. MR assessment of myocardial perfusion, viability, and function after intramyocardial transfer of VM202, a new plasmid human hepatocyte growth factor in ischemic swine myocardium. Radiology. 2008 Oct; 249(1):107-18.
Jacquier A, Bucknor M, Do L, Robert P, Corot C, Higgins CB, Saeed M. P846, a new gadolinium based low diffusion magnetic resonance contrast agent, in characterizing occlusive infarcts, reperfused ischemic myocardium and reperfused infarcts in rats. MAGMA. 2008 May; 21(3):207-18.
Hepworth EJ, Bucknor M, Patel A, Vaughan WC. Nationwide survey on the use of image-guided functional endoscopic sinus surgery. Otolaryngol Head Neck Surg. 2006 Jul; 135(1):68-73.