Kondapa Naidu Bobba, PhD

Associate Professional Researcher
Assoc Professional Researcher

Publications

Meher N, Ashley GW, Bobba KN, Wadhwa A, Bidkar AP, Dasari C, Mu C, Sankaranarayanan RA, Serrano JAC, Raveendran A, Bulkley DP, Aggarwal R, Greenland NY, Oskowitz A, Wilson DM, Seo Y, Santi DV, VanBrocklin HF, Flavell RR. Prostate-Specific Membrane Antigen Targeted StarPEG Nanocarrier for Imaging and Therapy of Prostate Cancer. Adv Healthc Mater. 2024 May 03; e2304618.
Wadhwa A, Wang S, Patiño-Escobar B, Bidkar AP, Bobba KN, Chan E, Meher N, Bidlingmaier S, Su Y, Dhrona S, Geng H, Sarin V, VanBrocklin HF, Wilson DM, He J, Zhang L, Steri V, Wong SW, Martin TG, Seo Y, Liu B, Wiita AP, Flavell RR. CD46-Targeted Theranostics for PET and 225Ac-Radiopharmaceutical Therapy of Multiple Myeloma. Clin Cancer Res. 2024 03 01; 30(5):1009-1021.
Sorlin AM, López-Álvarez M, Biboy J, Gray J, Rabbitt SJ, Rahim JU, Lee SH, Bobba KN, Blecha J, Parker MFL, Flavell RR, Engel J, Ohliger M, Vollmer W, Wilson DM. Peptidoglycan-Targeted [18F]3,3,3-Trifluoro-d-alanine Tracer for Imaging Bacterial Infection. JACS Au. 2024 Mar 25; 4(3):1039-1047.
Bobba KN, Bidkar AP, Wadhwa A, Meher N, Drona S, Sorlin AM, Bidlingmaier S, Zhang L, Wilson DM, Chan E, Greenland NY, Aggarwal R, VanBrocklin HF, He J, Chou J, Seo Y, Liu B, Flavell RR. Development of CD46 targeted alpha theranostics in prostate cancer using 134Ce/225Ac-Macropa-PEG4-YS5. Theranostics. 2024; 14(4):1344-1360.
Lee SH, Kim JM, López-Álvarez M, Wang C, Sorlin AM, Bobba KN, Pichardo-González PA, Blecha J, Seo Y, Flavell RR, Engel J, Ohliger MA, Wilson DM. Imaging the Bacterial Cell Wall Using N-Acetyl Muramic Acid-Derived Positron Emission Tomography Radiotracers. ACS Sens. 2023 Dec 22; 8(12):4554-4565.
Frame E, Bobba K, Gunter D, Mihailescu L, Bidkar A, Flavell R, Vetter K. Coded aperture and Compton imaging for the development of 225 Ac-based radiopharmaceuticals. Med Phys. 2023 Oct; 50(10):6454-6468.
Sorlin AM, López-Álvarez M, Rabbitt SJ, Alanizi AA, Shuere R, Bobba KN, Blecha J, Sakhamuri S, Evans MJ, Bayles KW, Flavell RR, Rosenberg OS, Sriram R, Desmet T, Nidetzky B, Engel J, Ohliger MA, Fraser JS, Wilson DM. Chemoenzymatic Syntheses of Fluorine-18-Labeled Disaccharides from [18F] FDG Yield Potent Sensors of Living Bacteria In Vivo. J Am Chem Soc. 2023 08 16; 145(32):17632-17642.
Klauser PC, Chopra S, Cao L, Bobba KN, Yu B, Seo Y, Chan E, Flavell RR, Evans MJ, Wang L. Covalent Proteins as Targeted Radionuclide Therapies Enhance Antitumor Effects. ACS Cent Sci. 2023 Jun 28; 9(6):1241-1251.
Sorlin AM, López-Álvarez M, Rabbitt SJ, Alanizi AA, Shuere R, Bobba KN, Blecha J, Sakhamuri S, Evans MJ, Bayles KW, Flavell RR, Rosenberg OS, Sriram R, Desmet T, Nidetzky B, Engel J, Ohliger MA, Fraser JS, Wilson DM. Chemoenzymatic syntheses of fluorine-18-labeled disaccharides from [ 18 F]FDG yield potent sensors of living bacteria in vivo. bioRxiv. 2023 May 20.
Bobba KN, Bidkar AP, Meher N, Fong C, Wadhwa A, Dhrona S, Sorlin A, Bidlingmaier S, Shuere B, He J, Wilson DM, Liu B, Seo Y, VanBrocklin HF, Flavell RR. Evaluation of 134Ce/134La as a PET Imaging Theranostic Pair for 225Ac α-Radiotherapeutics. J Nucl Med. 2023 07; 64(7):1076-1082.
Bidkar AP, Wang S, Bobba KN, Chan E, Bidlingmaier S, Egusa EA, Peter R, Ali U, Meher N, Wadhwa A, Dhrona S, Dasari C, Beckford-Vera D, Su Y, Tang R, Zhang L, He J, Wilson DM, Aggarwal R, VanBrocklin HF, Seo Y, Chou J, Liu B, Flavell RR. Treatment of Prostate Cancer with CD46-targeted 225Ac Alpha Particle Radioimmunotherapy. Clin Cancer Res. 2023 05 15; 29(10):1916-1928.
Rajendran G, Bhanu D, Aruchamy B, Ramani P, Pandurangan N, Bobba KN, Oh EJ, Chung HY, Gangadaran P, Ahn BC. Chalcone: A Promising Bioactive Scaffold in Medicinal Chemistry. Pharmaceuticals (Basel). 2022 Oct 11; 15(10).
Lee W, Bobba KN, Kim JY, Park H, Bhise A, Kim W, Lee K, Rajkumar S, Nam B, Lee KC, Lee SH, Ko S, Lee HJ, Jung ST, Yoo J. Correction: A short PEG linker alters the in vivo pharmacokinetics of trastuzumab to yield high-contrast immuno-PET images. J Mater Chem B. 2021 Aug 04; 9(30):6092.
Lee W, Bobba KN, Kim JY, Park H, Bhise A, Kim W, Lee K, Rajkumar S, Nam B, Lee KC, Lee SH, Ko S, Lee HJ, Jung ST, Yoo J. A short PEG linker alters the in vivo pharmacokinetics of trastuzumab to yield high-contrast immuno-PET images. J Mater Chem B. 2021 04 07; 9(13):2993-2997.
Lee W, Sarkar S, Pal R, Kim JY, Park H, Huynh PT, Bhise A, Bobba KN, Kim KI, Ha YS, Soni N, Kim W, Lee K, Jung JM, Rajkumar S, Lee KC, Yoo J. Successful Application of CuAAC Click Reaction in Constructing 64Cu-Labeled Antibody Conjugates for Immuno-PET Imaging. ACS Appl Bio Mater. 2021 03 15; 4(3):2544-2557.
Koo S, Bobba KN, Cho MY, Park HS, Won M, Velusamy N, Hong KS, Bhuniya S, Kim JS. Molecular Theranostic Agent with Programmed Activation for Hypoxic Tumors. ACS Appl Bio Mater. 2019 Oct 21; 2(10):4648-4655.
Kim JY, Sarkar S, Bobba KN, Huynh PT, Bhise A, Yoo J. Development of dansyl based copper(ii) complex to detect hydrogen sulfide in hypoxia. Org Biomol Chem. 2019 07 24; 17(29):7088-7094.
Bobba KN, Binoy A, Koo S, Nedungadi D, Podder A, Sharma A, Mishra N, Kim JS, Bhuniya S. Direct readout protonophore induced selective uncoupling and dysfunction of individual mitochondria within cancer cells. Chem Commun (Camb). 2019 May 30; 55(45):6429-6432.
Bobba KN, Saranya G, Sujai PT, Joseph MM, Velusamy N, Podder A, Maiti KK, Bhuniya S. Endogenous H2S-Assisted Cancer-Cell-Specific Activation of Theranostics with Emission Readout. ACS Appl Bio Mater. 2019 Mar 18; 2(3):1322-1330.
Velusamy N, Thirumalaivasan N, Bobba KN, Podder A, Wu SP, Bhuniya S. FRET-based dual channel fluorescent probe for detecting endogenous/exogenous H2O2/H2S formation through multicolor images. J Photochem Photobiol B. 2019 Feb; 191:99-106.
Zhou Y, Maiti M, Sharma A, Won M, Yu L, Miao LX, Shin J, Podder A, Bobba KN, Han J, Bhuniya S, Kim JS. Azo-based small molecular hypoxia responsive theranostic for tumor-specific imaging and therapy. J Control Release. 2018 10 28; 288:14-22.
Velusamy N, Binoy A, Bobba KN, Nedungadi D, Mishra N, Bhuniya S. A bioorthogonal fluorescent probe for mitochondrial hydrogen sulfide: new strategy for cancer cell labeling. Chem Commun (Camb). 2017 Aug 11; 53(62):8802-8805.
Sunwoo K, Bobba KN, Lim JY, Park T, Podder A, Heo JS, Lee SG, Bhuniya S, Kim JS. A bioorthogonal 'turn-on' fluorescent probe for tracking mitochondrial nitroxyl formation. Chem Commun (Camb). 2017 Feb 04; 53(10):1723-1726.
Zhou Y, Bobba KN, Lv XW, Yang D, Velusamy N, Zhang JF, Bhuniya S. A biotinylated piperazine-rhodol derivative: a 'turn-on' probe for nitroreductase triggered hypoxia imaging. Analyst. 2017 01 16; 142(2):345-350.
Dutta D, Alex SM, Bobba KN, Maiti KK, Bhuniya S. New Insight into a Cancer Theranostic Probe: Efficient Cell-Specific Delivery of SN-38 Guided by Biotinylated Poly(vinyl alcohol). ACS Appl Mater Interfaces. 2016 Dec 14; 8(49):33430-33438.