Jaewon Yang, PhD

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Biography

Jaewon Yang, PhD, is an Associate Specialist in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Dr. Yang's particular research interest is to develop practical and robust imaging techniques for quantitative PET and SPECT, providing a solution for the unmet needs of the current nuclear imaging systems.

Dr. Yang has extensively experienced quantitative data analysis using PET/MR data, developing PET quantitative imaging techniques readily applicable to daily clinics for attenuation correction and motion management.

Recently, he has completed the initial investigation of a direct image-to-image deep learning (DL) solution for simultaneous correction of attenuation and scatter in quantitative PET imaging. He continues to develop and validate the DL solution for clinical applications in commercial scanners that need practical and robust methods for quantitative PET and SPECT imaging.

Education

Ph.D., 04/2014 - Radiation Oncology and Electrical Engineering, Stanford University
M.S., 09/2010 - Electrical Engineering, Stanford University
B.S., 08/2007 - Electrical Engineering, Yonsei University
Postdoc, - Radiology and Biomedical Imaging, University of California, San Francisco (UCSF)

Honors and Awards

Fellowship, Kwanjeong Educational Foundation (KEF), 2007-2013
Graduation with Highest Honors, Electrical and Electronic Engineering, Yonsei University, 2007

Publications

Abioye AI, Okuneye TA, Odesanya AO, Adisa O, Abioye AI, Soipe AI, Ismail KA, Yang JF, Fasehun LK, Omotayo MO. Calcium Intake and Iron Status in Human Studies: A Systematic Review and Dose-Response Meta-Analysis of Randomized Trials and Crossover Studies. J Nutr. 2021 05 11; 151(5):1084-1101.
Yang J, Shi L, Wang R, Miller EJ, Sinusas AJ, Liu C, Gullberg GT, Seo Y. Direct Attenuation Correction Using Deep Learning for Cardiac SPECT: A Feasibility Study. J Nucl Med. 2021 11; 62(11):1645-1652.
Mahsa Torkaman, Jaewon Yang, Luyao Shi, Rui Wang, Edward J. Miller, Albert J. Sinusas, Chi Liu, Grant T. Gullberg, Youngho Seo. Data Management and Network Architecture Effect on Performance Variability in Direct Attenuation Correction via Deep Learning for Cardiac SPECT: A Feasibility Study. IEEE Transactions on Radiation and Plasma Medical Sciences. 2021 Jan 1; PP(99):1-1.
Jaewon Yang, Jae Ho Sohn, Spencer C. Behr, Grant T. Gullberg, Youngho Seo. CT-Less Direct Correction of Attenuation and Scatter in Image Space Using Deep Learning for Whole-Body FDG PET: Potential Benefits and Pitfalls. Radiology Artificial Intelligence. 2020 Dec 2; e200137.
Kuang Gong, Jaewon Yang, Peder E.Z. Larson, Spencer C. Behr, Thomas A. Hope, Youngho Seo, Quanzheng Li. MR-based Attenuation Correction for Brain PET Using 3D Cycle-Consistent Adversarial Network. IEEE Transactions on Radiation and Plasma Medical Sciences. 2020 Jan 1; PP(99):1-1.
Yang J, Park D, Gullberg GT, Seo Y. Joint correction of attenuation and scatter in image space using deep convolutional neural networks for dedicated brain 18F-FDG PET. Phys Med Biol. 2019 04 04; 64(7):075019.
Kim K, Kim D, Yang J, El Fakhri G, Seo Y, Fessler JA, Li Q. Time of flight PET reconstruction using nonuniform update for regional recovery uniformity. Med Phys. 2019 Feb; 46(2):649-664.
El Fakhri G. Iterative PET Image Reconstruction Using Convolutional Neural Network Representation. IEEE Trans Med Imaging. 2019 03; 38(3):675-685.
Yang J, Liu J, Wiesinger F, Menini A, Zhu X, Hope TA, Seo Y, Larson PEZ. Developing an efficient phase-matched attenuation correction method for quiescent period PET in abdominal PET/MRI. Phys Med Biol. 2018 09 10; 63(18):185002.
Gong K, Yang J, Kim K, El Fakhri G, Seo Y, Li Q. Attenuation correction for brain PET imaging using deep neural network based on Dixon and ZTE MR images. Phys Med Biol. 2018 06 13; 63(12):125011.
Wiesinger F, Bylund M, Yang J, Kaushik S, Shanbhag D, Ahn S, Jonsson JH, Lundman JA, Hope T, Nyholm T, Larson P, Cozzini C. Zero TE-based pseudo-CT image conversion in the head and its application in PET/MR attenuation correction and MR-guided radiation therapy planning. Magn Reson Med. 2018 10; 80(4):1440-1451.
Leynes AP, Yang J, Wiesinger F, Kaushik SS, Shanbhag DD, Seo Y, Hope TA, Larson PEZ. Zero-Echo-Time and Dixon Deep Pseudo-CT (ZeDD CT): Direct Generation of Pseudo-CT Images for Pelvic PET/MRI Attenuation Correction Using Deep Convolutional Neural Networks with Multiparametric MRI. J Nucl Med. 2018 05; 59(5):852-858.
Yang J, Wiesinger F, Kaushik S, Shanbhag D, Hope TA, Larson PEZ, Seo Y. Evaluation of Sinus/Edge-Corrected Zero-Echo-Time-Based Attenuation Correction in Brain PET/MRI. J Nucl Med. 2017 11; 58(11):1873-1879.
Yang J, Khalighi M, Hope TA, Ordovas K, Seo Y. Technical Note: Fast respiratory motion estimation using sorted singles without unlist processing: A feasibility study. Med Phys. 2017 May; 44(5):1632-1637.
Leynes AP, Yang J, Shanbhag DD, Kaushik SS, Seo Y, Hope TA, Wiesinger F, Larson PE. Hybrid ZTE/Dixon MR-based attenuation correction for quantitative uptake estimation of pelvic lesions in PET/MRI. Med Phys. 2017 Mar; 44(3):902-913.
Yang J, Jian Y, Jenkins N, Behr SC, Hope TA, Larson PEZ, Vigneron D, Seo Y. Quantitative Evaluation of Atlas-based Attenuation Correction for Brain PET in an Integrated Time-of-Flight PET/MR Imaging System. Radiology. 2017 07; 284(1):169-179.
Behr SC, Mollard BJ, Yang J, Flavell RR, Hawkins RA, Seo Y. Effect of Time-of-Flight and Regularized Reconstructions on Quantitative Measurements and Qualitative Assessments in Newly Diagnosed Prostate Cancer With 18F-Fluorocholine Dual Time Point PET/MRI. Mol Imaging. 2017 Jan-Dec; 16:1536012117736703.
Choi JY, Yang J, Noworolski SM, Behr S, Chang AJ, Simko JP, Nguyen HG, Carroll PR, Kurhanewicz J, Seo Y. 18F Fluorocholine Dynamic Time-of-Flight PET/MR Imaging in Patients with Newly Diagnosed Intermediate- to High-Risk Prostate Cancer: Initial Clinical-Pathologic Comparisons. Radiology. 2017 Feb; 282(2):429-436.
Yang J, Yamamoto T, Pollock S, Berger J, Diehn M, Graves EE, Loo BW, Keall PJ. The impact of audiovisual biofeedback on 4D functional and anatomic imaging: Results of a lung cancer pilot study. Radiother Oncol. 2016 08; 120(2):267-72.
Savic D, Pedoia V, Seo Y, Yang J, Bucknor M, Franc BL, Majumdar S. Imaging Bone-Cartilage Interactions in Osteoarthritis Using [18F]-NaF PET-MRI. Mol Imaging. 2016 01 01; 15:1-12.
P Keall, J Yang, T Yamamoto, S Pollock, M Diehn, J Berger, E Graves, B Loo. SU-D-17A-04: The Impact of Audiovisual Biofeedback On Image Quality During 4D Functional and Anatomic Imaging: Results of a Prospective Clinical Trial. Medical Physics. 2014 Jun 1; 41(6Part3):117-117.
A Nanduri, Q Fan, J Yang, T Yamamoto, E Graves, B Loo, S Mazin. TH-E-BRF-11: Dynamic Treatment of Clinical Margins Beyond the PET-Avid Target in Emission Guided Radiation Therapy: A Retrospective Patient Study. Medical Physics. 2014 Jun 1; 41(6Part33):571-571.
Yang J, Yamamoto T, Mazin SR, Graves EE, Keall PJ. The potential of positron emission tomography for intratreatment dynamic lung tumor tracking: a phantom study. Med Phys. 2014 Feb; 41(2):021718.
Q. Fan, A. Nanduri, J. Yang, T. Yamamoto, B. Loo, E. Graves, L. Zhu, S. Mazin. Simultaneous Tracking of Multiple Metastases Using FDG-PET Emission-Guided Radiation Therapy (EGRT) in a Breast Cancer Patient. International Journal of Radiation Oncology • Biology • Physics. 2013 Oct 1; 87(2):s95.
Fan Q, Nanduri A, Yang J, Yamamoto T, Loo B, Graves E, Zhu L, Mazin S. Toward a planning scheme for emission guided radiation therapy (EGRT): FDG based tumor tracking in a metastatic breast cancer patient. Med Phys. 2013 Aug; 40(8):081708.
Q Fan, A Nanduri, J Yang, T Yamamoto, B Loo, E Graves, L Zhu, S Mazin. SU-F-500-06: Demonstration of a Planning Scheme for Emission Guided Radiation Therapy (EGRT) in a Metastatic Breast Cancer Patient. Medical Physics. 2013 Jun 1; 40(6Part23):383-384.
J Yang, T Yamamoto, S Mazin, J Cui, E Graves, P Keall. TH-A-WAB-09: The Potential of Positron Emission Tomography (PET) for Intra-Treatment Dynamic Tumor Tracking During Radiotherapy: A Phantom Study. Medical Physics. 2013 Jun 1; 40(6Part31):521-521.
J Yang, T Yamamoto, S Gopalan, J Berger, E Johnston, M Chung, N Eclov, M Diehn, B Loo, E Graves, P Keall. TU-G-141-08: Impact of Audiovisual Biofeedback Respiratory Training On 4D-PET Image Quality. Medical Physics. 2013 Jun 1; 40(6Part27):457-458.
S Mazin, A Nanduri, J Yang, T Yamamoto, B Loo, E Graves. TU-A-BRA-05: Lung Cancer Patient Feasibility Study for Emission Guided Radiation Therapy. Medical Physics. 2012 Jun 1; 39(6Part22):3888-3889.
Yang J, Yamamoto T, Cho B, Seo Y, Keall PJ. The impact of audio-visual biofeedback on 4D PET images: results of a phantom study. Med Phys. 2012 Feb; 39(2):1046-57.
S Mazin, J Yang, T Yamamoto, A Nanduri. SU-E-J-154: Free Breathing Motion Tracking in Emission Guided Radiation Therapy. Medical Physics. 2011 Jun 1; 38(6Part9):3478-3478.
J Yang, T Yamamoto, K Thielemans, S Mazin, E Graves, P Keall. SU-E-J-156: A Feasibility Study for Real-Time Tumor Tracking Using Positron Emission Tomography (PET). Medical Physics. 2011 Jun 1; 38(6Part9):3479-3479.