Eric Mastria, MD, PhD



06/2018 - General Surgery Internship, UCSF
MD, 05/2017 - Medicine, Duke University
PhD, 06/2016 - Biomedical Engineering, Duke University
BSE, 05/2009 - Chemical Engineering, University of Michigan


Kumar P, Yee C, Blecha JE, Hayes TR, Kilbride BF, Stillson C, Losey AD, Mastria E, Jordan CD, Huynh TL, Moore T, Wilson MW, VanBrocklin HF, Hetts SW. Evaluating Radioactive Analogs of Doxorubicin to Quantify ChemoFilter Binding and Whole-Body Positron Emission Tomography/Magnetic Resonance Imaging for Drug Biodistribution. J Vasc Interv Radiol. 2022 Jun; 33(6):687-694.
Kelly G, Milligan JJ, Mastria EM, Kim S, Zelenetz SR, Dobbins J, Cai LY, Li X, Nair SK, Chilkoti A. Intratumoral delivery of brachytherapy and immunotherapy by a thermally triggered polypeptide depot. J Control Release. 2022 03; 343:267-276.
Dodd RD, Scherer A, Huang W, McGivney GR, Gutierrez WR, Laverty EA, Ashcraft KA, Stephens VR, Yousefpour P, Saha S, Knepper-Adrian V, Floyd W, Chen M, Ma Y, Mastria EM, Cardona DM, Eward WC, Chilkoti A, Kirsch DG. Tumor Subtype Determines Therapeutic Response to Chimeric Polypeptide Nanoparticle-based Chemotherapy in Pten-deleted Mouse Models of Sarcoma. Clin Cancer Res. 2020 09 15; 26(18):5036-5047.
Mastria EM, Cai LY, Kan MJ, Li X, Schaal JL, Fiering S, Gunn MD, Dewhirst MW, Nair SK, Chilkoti A. Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity. J Control Release. 2018 01 10; 269:364-373.
Luginbuhl KM, Schaal JL, Umstead B, Mastria EM, Li X, Banskota S, Arnold S, Feinglos M, D'Alessio D, Chilkoti A. One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer. Nat Biomed Eng. 2017; 1.
Wang J, Bhattacharyya J, Mastria E, Chilkoti A. A quantitative study of the intracellular fate of pH-responsive doxorubicin-polypeptide nanoparticles. J Control Release. 2017 08 28; 260:100-110.
Schaal JL, Li X, Mastria E, Bhattacharyya J, Zalutsky MR, Chilkoti A, Liu W. Injectable polypeptide micelles that form radiation crosslinked hydrogels in situ for intratumoral radiotherapy. J Control Release. 2016 Apr 28; 228:58-66.
Mastria EM, Chen M, McDaniel JR, Li X, Hyun J, Dewhirst MW, Chilkoti A. Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma. J Control Release. 2015 Jun 28; 208:52-8.
Thompson AJ, Mastria EM, Eniola-Adefeso O. The margination propensity of ellipsoidal micro/nanoparticles to the endothelium in human blood flow. Biomaterials. 2013 Jul; 34(23):5863-71.
Heslinga MJ, Mastria EM, Eniola-Adefeso O. Fabrication of biodegradable spheroidal microparticles for drug delivery applications. J Control Release. 2009 Sep 15; 138(3):235-42.