Killing Cancer Tumors with Ablation Therapy
Available Ablative Therapies
Variables
- Routes (percutaneous, laparoscopic, open surgical)
- Mechanism (chemotoxicity, thermal destruction, membrane alteration)
- Endpoints (imaging, temperature, impedence, time)
SAEs: Pain, Bleeding, Non-target ablation (bile duct, diaphragm, GI tract, gallbladder), Sepsis, Pleural effusion/ascites
All tumors respond to ablation: By virtue of the technique, there is no “tumor resistance”
Only appropriate for limited tumor burden
- Maximum is no more than five tumors, none exceeding five centimeters in size
- Optimum is three or fewer tumors, none of which exceed three centimeters in size