Drs. Ofer Pasternak and Martha Shenton Talk
Date
Microstructural alterations in brain disorders revealed by free-water imaging
Drs. Ofer Pasternak and Martha Shenton will be giving a presentation today (3/19) at 2pm in the CIND Conference Room (SFVAMC – Building 13).
Ofer Pasternak, PhD
Instructor, Psychiatry
Brigham and Women's Hospital
Harvard Medical School
Martha Shenton, PhD
Professor and Director,
Psychiatry Neuroimaging Laboratory,
Brigham and Women's Hospital,
Harvard Medical School
Title: “Microstructural alterations in brain disorders revealed by free-water imaging”
Abstract:
Diffusion MRI has been a powerful tool in the study of microstructural pathologies related to various brain disorders. We have recently proposed free-water imaging as an analysis method for diffusion MRI, which reduces partial volume effects of brain tissue and extracellular free-water. The volume of free-water is immerging as a new and clinically important marker, which may indicate neuroinflammation in early stages of brain disorders, and atrophy in latter stages. Diffusivities corrected for free-water appear to show better separation between patients and controls, and increase our ability to relate underlying pathologies with diffusion MRI changes. This talk will present the free-water methodology, and its applications to various brain disorders, including schizophrenia, Alzheimer’s disease, and brain injuries.
Bio:
Ofer Pasternak, PhD, is an Instructor in Psychiatry, Brigham and Women’s Hospital, Harvard Medical School. He graduated from the Interdisciplinary Program for Outstanding Students at Tel-Aviv University, Israel, where he obtained his BSc and PhD in computer science. Dr. Pasternak joined Harvard Medical School on October 2009 as a Fulbright post-doctoral fellow working under the joint supervision of Dr. Martha Shenton at the Psychiatry Neuroimaging Laboratory and Dr. Carl-Fredrik Westin at the Laboratory for Mathematics in Imaging. On 2012 he was awarded the NARSAD young investigator award from the Brain and Behavior Research Foundation.
Please come by and enjoy their talk!
Type
Time Duration
Microstructural alterations in brain disorders revealed by free-water imaging
Drs. Ofer Pasternak and Martha Shenton will be giving a presentation today (3/19) at 2pm in the CIND Conference Room (SFVAMC – Building 13).
Ofer Pasternak, PhD
Instructor, Psychiatry
Brigham and Women's Hospital
Harvard Medical School
Martha Shenton, PhD
Professor and Director,
Psychiatry Neuroimaging Laboratory,
Brigham and Women's Hospital,
Harvard Medical School
Title: “Microstructural alterations in brain disorders revealed by free-water imaging”
Abstract:
Diffusion MRI has been a powerful tool in the study of microstructural pathologies related to various brain disorders. We have recently proposed free-water imaging as an analysis method for diffusion MRI, which reduces partial volume effects of brain tissue and extracellular free-water. The volume of free-water is immerging as a new and clinically important marker, which may indicate neuroinflammation in early stages of brain disorders, and atrophy in latter stages. Diffusivities corrected for free-water appear to show better separation between patients and controls, and increase our ability to relate underlying pathologies with diffusion MRI changes. This talk will present the free-water methodology, and its applications to various brain disorders, including schizophrenia, Alzheimer’s disease, and brain injuries.
Bio:
Ofer Pasternak, PhD, is an Instructor in Psychiatry, Brigham and Women’s Hospital, Harvard Medical School. He graduated from the Interdisciplinary Program for Outstanding Students at Tel-Aviv University, Israel, where he obtained his BSc and PhD in computer science. Dr. Pasternak joined Harvard Medical School on October 2009 as a Fulbright post-doctoral fellow working under the joint supervision of Dr. Martha Shenton at the Psychiatry Neuroimaging Laboratory and Dr. Carl-Fredrik Westin at the Laboratory for Mathematics in Imaging. On 2012 he was awarded the NARSAD young investigator award from the Brain and Behavior Research Foundation.
Please come by and enjoy their talk!