Dr. Oliver Schmitt - Modeling brain connectivity: Connectomics and connectoms of the nervous systems of rats
Date
Dr. Oliver Schmitt will be giving a presentation this Wednesday, September 18, 2013 at 4pm in the CIND Conference Room (SFVA).
Oliver Schmitt, M.D., Ph.D.
Professor, Department of Anatomy
University of Rostock, Germany
Title: “Modeling brain connectivity: Connectomics and connectoms of the nervous systems of rats”
Info:
A connectome is a formal representation of connections between parts of a nervous system. Connectomics provides methods to generate and analyze these formal presentations. A really short overview of connectomics will be given to introduce the pros and cons of micro-, meso-, macroconnectomes generated by DTI, viral and non-viral tract tracing as well as high-throughput approaches. The neuroVIISAS framework is a generic platform allowing to work with different connectomes of different species and of nervous systems generated by the aforementioned methods. Using this generic framework the directed connections of most of the peer-reviewed tract tracing studies have collated in the rat connectome project. In contrast to comparable work a hierarchically organized bilateral connectome of the peripheral and central nervous system of the rat will be described with regard to structural features and quantitative properties. The third part of the talk characterizes the connectome of the cerebral cortex of the rat. Especially, those cerebral regions and their connectivity that are affected by experimental cerebral infarcts will be outlined. An out view of multivariate methods of analyzing connectoms, advanced visualization of multiscale connectomes and population-based simulations using connectoms will complete this talk.
Background:
Dr. Oliver Schmitt studied medicine at the University of Lübeck. In his thesis he investigated spatial relations of different types of neuron populations in the human putamen. Since 1991 he was a reasearch assistant at the Department of Anatomy of the University of Lübeck. In his postdoctoral research he developed methods to integrate multimodal cytoarchitectonical data of the human brain (2001). 2004 he starts to study the connectome of the rat nervous system. 2007 he was nominated as an adjunct professor in the Department of Anatomy of the University of Rostock. His research interests are neurodegenerative diseases, neuroinformatics, neurocomputing and population modelling using connectome data, neuroimaging, image registration, computer vision for the recognition of cell populations in histological sections.
Please come and enjoy Dr. Schmitt’s talk!
Time Duration
Dr. Oliver Schmitt will be giving a presentation this Wednesday, September 18, 2013 at 4pm in the CIND Conference Room (SFVA).
Oliver Schmitt, M.D., Ph.D.
Professor, Department of Anatomy
University of Rostock, Germany
Title: “Modeling brain connectivity: Connectomics and connectoms of the nervous systems of rats”
Info:
A connectome is a formal representation of connections between parts of a nervous system. Connectomics provides methods to generate and analyze these formal presentations. A really short overview of connectomics will be given to introduce the pros and cons of micro-, meso-, macroconnectomes generated by DTI, viral and non-viral tract tracing as well as high-throughput approaches. The neuroVIISAS framework is a generic platform allowing to work with different connectomes of different species and of nervous systems generated by the aforementioned methods. Using this generic framework the directed connections of most of the peer-reviewed tract tracing studies have collated in the rat connectome project. In contrast to comparable work a hierarchically organized bilateral connectome of the peripheral and central nervous system of the rat will be described with regard to structural features and quantitative properties. The third part of the talk characterizes the connectome of the cerebral cortex of the rat. Especially, those cerebral regions and their connectivity that are affected by experimental cerebral infarcts will be outlined. An out view of multivariate methods of analyzing connectoms, advanced visualization of multiscale connectomes and population-based simulations using connectoms will complete this talk.
Background:
Dr. Oliver Schmitt studied medicine at the University of Lübeck. In his thesis he investigated spatial relations of different types of neuron populations in the human putamen. Since 1991 he was a reasearch assistant at the Department of Anatomy of the University of Lübeck. In his postdoctoral research he developed methods to integrate multimodal cytoarchitectonical data of the human brain (2001). 2004 he starts to study the connectome of the rat nervous system. 2007 he was nominated as an adjunct professor in the Department of Anatomy of the University of Rostock. His research interests are neurodegenerative diseases, neuroinformatics, neurocomputing and population modelling using connectome data, neuroimaging, image registration, computer vision for the recognition of cell populations in histological sections.
Please come and enjoy Dr. Schmitt’s talk!