Joseph Leach, MD, PhD
Assistant Professor in Residence
Assistant Professor in Res
Biography
Joseph Leach, MD, PhD obtained his PhD from the joint UCSF-UC Berkeley Bioengineering program in 2009. In 2013 Dr. Leach earned his medical degree at UCSF, followed by a one-year internship at California Pacific Medical Center of San Francisco. Dr. Leach completed a four-year Diagnostic Radiology residency at UCSF in 2018. During 2017-2018 Dr. Leach was a NIH T32 Training Grant research fellow at UCSF Radiology, where he focused his research on the development of methodologies by which to study the biomechanics of abdominal aortic aneurysms (AAA) on a patient-specific basis, incorporating data from both routine clinical and more advanced imaging modalities. Dr. Leach completed a clinical fellowship in Abdominal Imaging/Ultrasound at UCSF in 2019.
Dr. Leach joined the department as an assistant professor in residence in the section of Abdominal Imaging in July 2019.
Education
Fellowship, 2019 - Abdominal Imaging; Ultrasound, UCSF, Department of Radiology & Biomedical Imaging
NIH T32 Research Fellowship, 2018 - , UCSF, Department of Radiology & Biomedical Imaging
Residency, 2018 - Diagnostic Radiology, UCSF, Department of Radiology & Biomedical Imaging
Internship, 2014 - , California Pacific Medical Center
MD, 2013 - Medicine, UCSF, School of Medicine
PhD, 2009 - Bioengineering, UCSF-UC Berkeley Joint Bioengineering Program
Honors and Awards
Outstanding Resident Research Award, Margulis Society, UCSF Radiology & Biomedical Imaging, 2018
Publications
Leach JR, Zhu C, Mitsouras D, Saloner D, Hope MD. Abdominal aortic aneurysm measurement at CT/MRI: potential clinical ramifications of non-standardized measurement technique and importance of multiplanar reformation. Quant Imaging Med Surg. 2021 Feb; 11(2):823-830.
Leach JR, Manoukian B, Stewart L. Mesh on the move: a case report of total transmural surgical mesh migration causing bowel obstruction. Clin J Gastroenterol. 2020 Nov 25.
Wang Y, Tian B, Xiong F, Kao E, Zhang Y, Liu X, Tian X, Haraldsson H, Zhu C, Leach J, Liu J, Hope MD, Mitsouras D, Saloner D. Computer-aided quantification of non-contrast 3D black blood MRI as an efficient alternative to reference standard manual CT angiography measurements of abdominal aortic aneurysms. Eur J Radiol. 2020 Nov 05; 134:109396.
Yan Wang, Bing Tian, Fei Xiong, Evan Kao, Yue Zhang, Xinke Liu, Xia Tian, Henrik Haraldsson, Chengcheng Zhu, Joseph Leach, Jing Liu, Michael D. Hope, Dimitrios Mitsouras, David Saloner. Computer-Aided Quantification of Non-contrast 3D Black Blood MRI As An Efficient Alternative to Reference Standard Manual CT Angiography Measurements of Abdominal Aortic Aneurysms. European Journal of Radiology. 2020 Nov 1; 109396.
Arushi Gulati, Zhongjie Wang, Yue Xuan, Joseph Leach, David A. Saloner, Julius M. Guccione, Liang Ge, Elaine E. Tseng. Wall Stress Changes in Ascending Thoracic Aortic Aneurysms Do Not Correlate with Changes in Diameter over Time. Journal of the American College of Surgeons. 2020 Oct 1; 231(4):s49.
Mitsouras D, Leach JR. Expanding the Radiologist's Arsenal against Abdominal Aortic Aneurysms, a Versatile Adversary. Radiology. 2020 06; 295(3):730-732.
Zhu C, Leach JR, Wang Y, Gasper W, Saloner D, Hope MD. Intraluminal Thrombus Predicts Rapid Growth of Abdominal Aortic Aneurysms. Radiology. 2020 03; 294(3):707-713.
Keerthi Valluru, James Parkhill, Ayushi Gautam, Henrik Haraldsson, Evan Kao, Joseph Leach, Alexandra Wright, Megan Ballweber, Karl Meisel, David Saloner, Matthew Amans. Sound Measurement in Patient-Specific 3D Printed Bench Models of Venous Pulsatile Tinnitus. Otology & Neurotology. 2020 Jan 1; 41(1):e7-e14.
M Amans, K Valluru, H Haraldsson, E Kao, J Leach, A Wright, M Ballweber, K Meisel, D Saloner. O-025 Sound measurement in patient-specific 3D printed bench models for venous pulsatile tinnitus. Journal of NeuroInterventional Surgery. 2019 Jul 1; 11(Suppl 1):a17.
Leach J, Kao E, Zhu C, Saloner D, Hope MD. On the relative impact of intraluminal thrombus heterogeneity on abdominal aortic aneurysm mechanics. J Biomech Eng. 2019 Jun 29.
JOSEPH R. LEACH, CHENGCHENG ZHU, DAVID SALONER, MICHAEL D. HOPE. COMPARISON OF TWO METHODS FOR ESTIMATING THE UNLOADED STATE FOR ABDOMINAL AORTIC ANEURYSM STRESS CALCULATIONS. Journal of Mechanics in Medicine and Biology. 2019 May 1; 19(03):1950015.
Zhu C, Leach JR, Tian B, Cao L, Wen Z, Wang Y, Liu X, Liu Q, Lu J, Saloner D, Hope MD. Evaluation of the distribution and progression of intraluminal thrombus in abdominal aortic aneurysms using high-resolution MRI. J Magn Reson Imaging. 2019 09; 50(3):994-1001.
Zhu C, Tian B, Leach JR, Liu Q, Lu J, Chen L, Saloner D, Hope MD. Non-contrast 3D black blood MRI for abdominal aortic aneurysm surveillance: comparison with CT angiography. Eur Radiol. 2017 May; 27(5):1787-1794.
Leach JR, Elicker B, Yee J, Puppula S, Wisneski JA, Yeh BM. Clot Through the Heart: Paradoxical Embolism With Thrombus-in-Transit at Multidetector Computed Tomography. J Comput Assist Tomogr. 2015 Jul-Aug; 39(4):598-600.
Leach JR, Rayz VL, Soares B, Wintermark M, Mofrad MR, Saloner D. Carotid atheroma rupture observed in vivo and FSI-predicted stress distribution based on pre-rupture imaging. Ann Biomed Eng. 2010 Aug; 38(8):2748-65.
Joseph R. Leach, Mohammad R. K. Mofrad, David Saloner. Computational Models of Vascular Mechanics. Computational Modeling in Biomechanics. 2010 Jan 1; 99-170.
Leach JR, Rayz VL, Mofrad MR, Saloner D. An efficient two-stage approach for image-based FSI analysis of atherosclerotic arteries. Biomech Model Mechanobiol. 2010 Apr; 9(2):213-23.
