Elias Botvinick, MD

Professor
PROF EMERITUS(WOS)

Biography

Elias H. Botvinick, MD, is a Professor in Residence, Co-Director of the Adult Cardiology Non-Invasive Laboratory, and Director of the Cardiac Stress Testing Laboratory at the University of California, San Francisco. Dr. Botvinick received his medical degree from New York University School of Medicine in 1967, and completed a residency in Medicine at Bellevue Hospital in New York, followed by a fellowship in Nuclear Medicine from UCSF in 1976.

Dr. Botvinick’s primary research interest has been scintigraphic methods. His research involves recent applications of the scintigraphic imaging agent indicates its ability to map the regional density of sympathetic nerves and support the hypothesis that an altered balance in the relationship of perfusion and innervation can increase vulnerability to life threatening arrhythmias. Overall, Dr. Botvinick’s research has been a collaborative effort to develop non-invasive graphic and imaging methods for the identification and evaluation of cardiac anatomy and pathophysiology, and apply them to the diagnosis, risk stratification and monitoring of clinical disease.

Dr. Botvinick has written 178 articles, 46 book chapters, 301 abstracts, with 8 significant publications.

Expertise:
Nuclear Medicine and Cardiology

Specialty:
Nuclear cardiology, scintigraphy, cardiovascular diseases

Professional Interests:
Nuclear medicine, nuclear cardiology, PET/CT, MRI, CT, cardiac cardiology, echo cardiology, nuclear magnetic resonance, cardiovascular imaging, stress testing, heart, myocardial perfusion, scintigraphy, coronary, synchrony, synchronization

Education and Training:
• Medical School: New York University School of Medicine, New York
• Internship: Bellevue Hospital, New York - Medicine
• Internship: United States Army, Hospital, Fort Riley
• Residency: Bellevue Hospital, New York - Medicine
• Fellowship: University of California, San Francisco - Nuclear Medicine
• New York State Medical License
• Controlled Substance Registration Certificate
• California State Medical
• Internal Medicine Boards
• Nuclear Medicine Boards
• Cardiovascular Boards
• Certified, Basic Cardiac Life Support
• Certified, Advanced Cardiac Life Support

Education

M.D., 1967 - School of Medicine, New York University
Clinical Fellowship, - School of Medicine, University of California, San Francisco
Residency, - School of Medicine - Cardiology, University of California, San Francisco

Honors and Awards

Best Doctor's in California, Cardiology & Nuclear Medicine, San Francisco Magazine, 2000
Founding Member ASNC, American Society of Nuclear Cardiology, 1998
Keynote Speaker, Graduation Nuclear Medicine Technology Training Program, 1994
Founder and First President of the Cardiovascular Council, Society of Nuclear Medicine, 1992
Recipient Herman H. Blumgart Lectureship Award, Society of Nuclear Medicine, 1991
Bronze Star Medal Award, Republic of Vietnam, United States Army, 1971
Nominated for UCSF Medical School Kaiser award for Excellence in Teaching, University of California, San Francisco School of Medicine

Publications

Sciammarella M, Shrestha UM, Seo Y, Gullberg GT, Botvinick EH. A combined static-dynamic single-dose imaging protocol to compare quantitative dynamic SPECT with static conventional SPECT. J Nucl Cardiol. 2017 Aug 03.
Pampaloni MH, Shrestha UM, Sciammarella M, Seo Y, Gullberg GT, Botvinick EH. Noninvasive PET quantitative myocardial blood flow with regadenoson for assessing cardiac allograft vasculopathy in orthotopic heart transplantation patients. J Nucl Cardiol. 2017 Aug; 24(4):1134-1144.
Badhwar N, James J, Hoffmayer KS, O'Connell JW, Green D, De Marco T, Botvinick EH. Utility of Equilibrium Radionuclide Angiogram-Derived Measures of Dyssynchrony to Predict Outcomes in Heart Failure Patients Undergoing Cardiac Resynchronization Therapy. J Nucl Med. 2016 Dec; 57(12):1880-1886.
Shrestha U, Sciammarella M, Alhassen F, Yeghiazarians Y, Ellin J, Verdin E, Boyle A, Seo Y, Botvinick EH, Gullberg GT. Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation. J Nucl Cardiol. 2017 Feb; 24(1):268-277.
Shrestha UM, Seo Y, Botvinick EH, Gullberg GT. Image reconstruction in higher dimensions: myocardial perfusion imaging of tracer dynamics with cardiac motion due to deformation and respiration. Phys Med Biol. 2015 Nov 07; 60(21):8275-301.
Johnson CJ, Roberts JD, James JH, Hoffmayer KS, Badhwar N, Ku IA, Zhao S, Naeger DM, Rao RK, O'Connell JW, De Marco T, Botvinick EH, Scheinman MM. Comparison of radionuclide angiographic synchrony analysis to echocardiography and magnetic resonance imaging for the diagnosis of arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2015 Jun; 12(6):1268-75.
Pampaloni MH, Nazer B, Botvinick E. Erratum to: Isolated right ventricular cardiac sarcoidosis demonstrated by (18)FDG positron emission tomography. J Nucl Cardiol. 2015 Feb; 22(1):221.
Shrestha U, Botvinick EH, Yeghiazarians Y, Seo Y, Gullberg GT. Quantitative Signature of Coronary Steal in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT. IEEE Nucl Sci Symp Conf Rec (1997). 2014 Nov; 2014.
Hernandez Pampaloni M, Nazer B, Nazar B, Botvinick E. Isolated right ventricular cardiac sarcoidosis demonstrated by ¹8FDG positron emission tomography. J Nucl Cardiol. 2014 Jun; 21(3):652-4.
Botvinick EH, O'Connell JW, Badhwar N. Imaging synchrony. J Nucl Cardiol. 2009 Nov-Dec; 16(6):846-8.
del Romeral LM, Stillson C, Lesh M, Botvinick E. The variable functional effects of the pacing site in normal and scarred ventricles. J Nucl Cardiol. 2009 Nov-Dec; 16(6):904-13.
del Romeral LM, Stillson C, Lesh M, Dae M, Botvinick E. The relationship of myocardial contraction and electrical excitation--the correlation between scintigraphic phase image analysis and electrophysiologic mapping. J Nucl Cardiol. 2009 Sep-Oct; 16(5):792-800.
Bural GG, Torigian DA, Botvinick E, Houseni M, Basu S, Chen W, Alavi A. A pilot study of changes in (18)F-FDG uptake, calcification and global metabolic activity of the aorta with aging. Hell J Nucl Med. 2009 May-Aug; 12(2):123-8.
Botvinick EH. Current methods of pharmacologic stress testing and the potential advantages of new agents. J Nucl Med Technol. 2009 Mar; 37(1):14-25.
Botvinick E, Davis J, Dae M, O'Connell J, Schechtmann N, Abbott J, Morady F, Lanzer P, Iskikian J, Scheinman M. Localization of ventricular tachycardia exit site and subsequent contraction sequence and functional effects with bedside radionuclide angiography. JACC Cardiovasc Imaging. 2008 Sep; 1(5):605-13.
Chen W, Botvinick EH, Alavi A, Zhang Y, Yang S, Perini R, Zhuang H. Age-related decrease in cardiopulmonary adrenergic neuronal function in children as assessed by I-123 metaiodobenzylguanidine imaging. J Nucl Cardiol. 2008 Jan-Feb; 15(1):73-9.
Hansen CL, Goldstein RA, Akinboboye OO, Berman DS, Botvinick EH, Churchwell KB, Cooke CD, Corbett JR, Cullom SJ, Dahlberg ST, Druz RS, Ficaro EP, Galt JR, Garg RK, Germano G, Heller GV, Henzlova MJ, Hyun MC, Johnson LL, Mann A, McCallister BD, Quaife RA, Ruddy TD, Sundaram SN, Taillefer R, Ward RP, Mahmarian JJ. Myocardial perfusion and function: single photon emission computed tomography. J Nucl Cardiol. 2007 Nov-Dec; 14(6):e39-60.
Botvinick EH, Perini R, Bural G, Chen W, Chryssikos T, Houseni M, Hernandez-Pampaloni M, Torigian DA, Alavi A. The aging of the heart and blood vessels: a consideration of anatomy and physiology in the era of computed tomography, magnetic resonance imaging, and positron emission tomographic imaging methods with special consideration of atherogenesis. Semin Nucl Med. 2007 Mar; 37(2):120-43.
Corbett JR, Akinboboye OO, Bacharach SL, Borer JS, Botvinick EH, DePuey EG, Ficaro EP, Hansen CL, Henzlova MJ, Van Kriekinge S. Equilibrium radionuclide angiocardiography. J Nucl Cardiol. 2006 Nov; 13(6):e56-79.
Funk T, Kirch DL, Koss JE, Botvinick E, Hasegawa BH. A novel approach to multipinhole SPECT for myocardial perfusion imaging. J Nucl Med. 2006 Apr; 47(4):595-602.
O'Connell JW, Schreck C, Moles M, Badwar N, DeMarco T, Olgin J, Lee B, Tseng Z, Kumar U, Botvinick EH. A unique method by which to quantitate synchrony with equilibrium radionuclide angiography. J Nucl Cardiol. 2005 Jul-Aug; 12(4):441-50.
Heller GV, Bateman TM, Johnson LL, Cullom SJ, Case JA, Galt JR, Garcia EV, Haddock K, Moutray KL, Poston C, Botvinick EH, Fish MB, Follansbee WP, Hayes S, Iskandrian AE, Mahmarian JJ, Vandecker W. Clinical value of attenuation correction in stress-only Tc-99m sestamibi SPECT imaging. J Nucl Cardiol. 2004 May-Jun; 11(3):273-81.
Pham KH, Botvinick EH. Increased right ventricular activity: artifact of camera head misalignment. J Nucl Cardiol. 2003 Sep-Oct; 10(5):575-6.
Botvinick EH. Scintigraphic blood pool and phase image analysis: the optimal tool for the evaluation of resynchronization therapy. J Nucl Cardiol. 2003 Jul-Aug; 10(4):424-8.
Yun JH, Block M, Botvinick EH. Unique contraction pattern in patients after coronary bypass graft surgery by gated SPECT myocardial perfusion imaging. Clin Nucl Med. 2003 Jan; 28(1):18-24.