Christopher Hess, MD, PhD

Alexander R. Margulis Distinguished Professor and Chair
Professor and Chair

Biography

Christopher Hess, MD, PhD, is the Alexander R. Margulis Distinguished Professor and Chair of the Department of Radiology and Biomedical Imaging at UCSF.

Dr. Hess completed his PhD in Electrical Engineering and his MD at the University of Illinois in 1998 and 2002, respectively. He was in the first class of NIH T32 radiology research program at UCSF in 2005-2006. He served as chief resident in Radiology from 2006-2007 and was the recipient of the RSNA's Roentgen Award in 2006 and the department's Elmer Ng Award for outstanding resident in 2007. After completing residency in 2007, he remained at UCSF and went on to complete his fellowship training in Neuroradiology the following year. He joined the UCSF faculty in the same year. After serving as Chief of Neuroradiology at the San Francisco VA, Fellowship Director for Neuroradiology at UCSF, and Chief of Neuroradiology at UCSF, he become the Chair of the Department of Radiology and Biomedical Imaging in 2018.

Dr. Hess’s research interests lie in the translational application of MR imaging techniques to vascular disease, brain development and degeneration, and epilepsy, especially using diffusion imaging and ultra-high-field MRI. He is a fellow of the American Institute for Medical and Biological Engineering, and serves on the editorial board of Radiology and the American Journal of Neuroradiology.

Expertise: Neuroradiology

Specialty: Neurodegenerative disorders, epilepsy, vascular disease

Professional Interests: Neurodegenerative disorders, epilepsy, vascular disease, image-guided spine interventions, diffusion MRI and fiber tractography, ultra-high field brain MRI, quantitative MRI

Education and Training:
• Medical School: University of Illinois, Urbana, IL, MD (1998-2002)
• Internship: California Pacific Medical Center, San Francisco - Internal Medicine (2002-2003)
• Residency: University of California, San Francisco - Radiology (2003-2007)
• Chief Residency: University of California, San Francisco - Chief Resident, Radiology (2006-2007)
• Fellowship: University of California, San Francisco - Neuroradiology (2007-2008)
• Board Certifications: Medical Licensure, California (2004)
• Board Certifications: American Board of Radiology (2007)
• Fluoroscopy Supervisor and Operator, California Department of Public Health (2007)
• Subspecialty Certification, Neuroradiology, American Board of Radiology (2009)

Education

Fellowship, 2008 - Neuroradiology, University of California, San Francisco
Residency, 2007 - Radiology, University of California, San Francisco
M.D., 2002 - School of Medicine, University of Illinois
Ph.D., 1999 - Electrical Engineering, University of Illinois

Honors and Awards

Elmer Ng Award for Outstanding Resident in Radiology, University of California, San Francisco, 2007
Best Paper Award in Functional Neuroradiology, American Society of Neuroradiology, 2006
Berlex Best Paper Award, General Neuroradiology, American Society of Neuroradiology, 2005
Alpha Omega Alpha, Alpha Chapter, University of Illinois, 2000
Eta Kappa Nu, 1990

Publications

Bonham LW, Steele NZR, Karch CM, Manzoni C, Geier EG, Wen N, Ofori-Kuragu A, Momeni P, Hardy J, Miller ZA, Hess CP, Lewis P, Miller BL, Seeley WW, Baranzini SE, Desikan RS, Ferrari R, Yokoyama JS. Protein network analysis reveals selectively vulnerable regions and biological processes in FTD. Neurol Genet. 2018 Oct; 4(5):e266.
Li Y, Barkovich MJ, Karch CM, Nillo RM, Fan CC, Broce IJ, Tan CH, Cuneo D, Hess CP, Dillon WP, Glenn OA, Glastonbury CM, Olney N, Yokoyama JS, Bonham LW, Miller B, Kao A, Schmansky N, Fischl B, Andreassen OA, Jernigan T, Dale A, Barkovich AJ, Desikan RS, Sugrue LP. Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex. Sci Rep. 2018 Sep 06; 8(1):13373.
Barkovich MJ, Tan CH, Nillo RM, Li Y, Xu D, Glastonbury CM, Glenn OA, Dillon WP, Hess CP, Mueller S, Kline C, Dale AM, Jernigan TL, Sugrue LP, Barkovich AJ, Desikan RS. Abnormal Morphology of Select Cortical and Subcortical Regions in Neurofibromatosis Type 1. Radiology. 2018 Sep 04; 172863.
Barkovich EJ, Jernstedt Barkovich M, Hess C. Ferromagnetic sand: A possible MRI hazard. Neuroradiol J. 2018 Aug 20; 1971400918795865.
Morrison MA, Payabvash S, Chen Y, Avadiappan S, Shah M, Zou X, Hess CP, Lupo JM. A user-guided tool for semi-automated cerebral microbleed detection and volume segmentation: Evaluating vascular injury and data labelling for machine learning. Neuroimage Clin. 2018; 20:498-505.
Wintermark M, Lee Y, Kerr A, Hess C, Dillon WP, Mukherji SK, Norbash A, Seidenwurm D, Law M. Impact of Neuroradiology Staffing on Academic Hospital Level Quality and Cost Measures for the Neuroscience Service Line. J Am Coll Radiol. 2018 Jul 26.
Garcia MA, Anwar M, Yu Y, Duriseti S, Merritt B, Nakamura J, Hess C, Theodosopoulos PV, McDermott M, Sneed PK, Braunstein SE. Brain metastasis growth on preradiosurgical magnetic resonance imaging. Pract Radiat Oncol. 2018 Jun 07.
Zhu C, Wang X, Degnan AJ, Shi Z, Tian B, Liu Q, Hess C, Saloner D, Lu J. Wall enhancement of intracranial unruptured aneurysm is associated with increased rupture risk and traditional risk factors. Eur Radiol. 2018 Jun 05.
Wu CX, Ma L, Chen XZ, Chen XL, Chen Y, Zhao YL, Hess C, Kim H, Jin HW, Ma J. Evaluation of Angioarchitectural Features of Unruptured Brain Arteriovenous Malformation by Susceptibility Weighted Image (SWI). World Neurosurg. 2018 May 30.
Bonham LW, Karch CM, Fan CC, Tan C, Geier EG, Wang Y, Wen N, Broce IJ, Li Y, Barkovich MJ, Ferrari R, Hardy J, Momeni P, Höglinger G, Müller U, Hess CP, Sugrue LP, Dillon WP, Schellenberg GD, Miller BL, Andreassen OA, Dale AM, Barkovich AJ, Yokoyama JS, Desikan RS. CXCR4 involvement in neurodegenerative diseases. Transl Psychiatry. 2018 Apr 11; 8(1):73.
Karch CM, Wen N, Fan CC, Yokoyama JS, Kouri N, Ross OA, Höglinger G, Müller U, Ferrari R, Hardy J, Schellenberg GD, Sleiman PM, Momeni P, Hess CP, Miller BL, Sharma M, Van Deerlin V, Smeland OB, Andreassen OA, Dale AM, Desikan RS. Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum. JAMA Neurol. 2018 Apr 09.
Nordstrom M, Felton E, Sear K, Tamrazi B, Torkildson J, Gauvain K, Haas-Kogan DA, Chen J, Buono BD, Banerjee A, Samuel D, Saloner D, Tian B, Roddy E, Hess C, Fullerton H, Mueller S. Large Vessel Arteriopathy After Cranial Radiation Therapy in Pediatric Brain Tumor Survivors. J Child Neurol. 2018 Apr; 33(5):359-366.
Barbaro NM, Quigg M, Ward MM, Chang EF, Broshek DK, Langfitt JT, Yan G, Laxer KD, Cole AJ, Sneed PK, Hess CP, Yu W, Tripathi M, Heck CN, Miller JW, Garcia PA, McEvoy A, Fountain NB, Salanova V, Knowlton RC, Bagic A, Henry T, Kapoor S, McKhann G, Palade AE, Reuber M, Tecoma E. Radiosurgery versus open surgery for mesial temporal lobe epilepsy: The randomized, controlled ROSE trial. Epilepsia. 2018 Mar 30.
Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J. Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. PLoS Med. 2018 Jan; 15(1):e1002504.
Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J. Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies. PLoS Med. 2018 01; 15(1):e1002487.
Zhu C, Tian B, Chen L, Eisenmenger L, Raithel E, Forman C, Ahn S, Laub G, Liu Q, Lu J, Liu J, Hess C, Saloner D. Accelerated whole brain intracranial vessel wall imaging using black blood fast spin echo with compressed sensing (CS-SPACE). MAGMA. 2017 Dec 05.
Staffaroni AM, Elahi FM, McDermott D, Marton K, Karageorgiou E, Sacco S, Paoletti M, Caverzasi E, Hess CP, Rosen HJ, Geschwind MD. Neuroimaging in Dementia. Semin Neurol. 2017 Oct; 37(5):510-537.
Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan RS. Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition. Acta Neuropathol. 2018 Jan; 135(1):85-93.
Steiner JE, McCoy GN, Hess CP, Dobyns WB, Metry DW, Drolet BA, Maheshwari M, Siegel DH. Structural malformations of the brain, eye, and pituitary gland in PHACE syndrome. Am J Med Genet A. 2018 Jan; 176(1):48-55.
Kim H, Kim JH, Possin KL, Winer J, Geschwind MD, Xu D, Hess CP. Surface-based morphometry reveals caudate subnuclear structural damage in patients with premotor Huntington disease. Brain Imaging Behav. 2017 Oct; 11(5):1365-1372.
Tan CH, Hyman BT, Tan JJX, Hess CP, Dillon WP, Schellenberg GD, Besser LM, Kukull WA, Kauppi K, McEvoy LK, Andreassen OA, Dale AM, Fan CC, Desikan RS. Polygenic hazard scores in preclinical Alzheimer disease. Ann Neurol. 2017 Sep; 82(3):484-488.
Chen X, Cooke DL, Saloner D, Nelson J, Su H, Lawton MT, Hess C, Tihan T, Zhao Y, Kim H. Higher Flow Is Present in Unruptured Arteriovenous Malformations With Silent Intralesional Microhemorrhages. Stroke. 2017 10; 48(10):2881-2884.
Wahl M, Anwar M, Hess CP, Chang SM, Lupo JM. Relationship between radiation dose and microbleed formation in patients with malignant glioma. Radiat Oncol. 2017 Aug 10; 12(1):126.
Mamlouk MD, Nicholson AD, Cooke DL, Hess CP. Diffusion-weighted imaging for cutaneous vascular anomalies. Clin Imaging. 2017 Nov - Dec; 46:121-122.
Mamlouk MD, Maheshwari M, Burrows PE, Siegel DH, Frieden IJ, Drolet BA, Hess CP. PHACE syndrome and cerebral cavernous malformations: association or simply microhemorrhages? Childs Nerv Syst. 2017 Sep; 33(9):1421-1422.
Mamlouk MD, Nicholson AD, Cooke DL, Hess CP. Tips and tricks to optimize MRI protocols for cutaneous vascular anomalies. Clin Imaging. 2017 Sep - Oct; 45:71-80.
Zou X, Hart BL, Mabray M, Bartlett MR, Bian W, Nelson J, Morrison LA, McCulloch CE, Hess CP, Lupo JM, Kim H. Automated algorithm for counting microbleeds in patients with familial cerebral cavernous malformations. Neuroradiology. 2017 Jul; 59(7):685-690.
Possin KL, Kim H, Geschwind MD, Moskowitz T, Johnson ET, Sha SJ, Apple A, Xu D, Miller BL, Finkbeiner S, Hess CP, Kramer JH. Egocentric and allocentric visuospatial working memory in premotor Huntington's disease: A double dissociation with caudate and hippocampal volumes. Neuropsychologia. 2017 Jul 01; 101:57-64.
Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. PLoS Med. 2017 Mar; 14(3):e1002258.
Patterson A, Okun MS, Hess C. High-voltage VIM Region Deep Brain Stimulation Mimicking Progressive Supranuclear Palsy. Tremor Other Hyperkinet Mov (N Y). 2017; 7:449.
Yokoyama JS, Karch CM, Fan CC, Bonham LW, Kouri N, Ross OA, Rademakers R, Kim J, Wang Y, Höglinger GU, Müller U, Ferrari R, Hardy J. Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia. Acta Neuropathol. 2017 May; 133(5):825-837.
Whitman IR, Gladstone RA, Badhwar N, Hsia HH, Lee BK, Josephson SA, Meisel KM, Dillon WP, Hess CP, Gerstenfeld EP, Marcus GM. Brain Emboli After Left Ventricular Endocardial Ablation. Circulation. 2017 Feb 28; 135(9):867-877.
Ferrari R, Wang Y, Vandrovcova J, Guelfi S, Witeolar A, Karch CM, Schork AJ, Fan CC, Brewer JB. Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases. J Neurol Neurosurg Psychiatry. 2017 02; 88(2):152-164.
Ziu M, Dunn IF, Hess C, Fleseriu M, Bodach ME, Tumialan LM, Oyesiku NM, Patel KS, Wang R, Carter BS, Chen JY, Chen CC, Patil CG, Litvack Z, Zada G, Aghi MK. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Posttreatment Follow-up Evaluation of Patients With Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 10; 79(4):E541-3.
Chen CC, Carter BS, Wang R, Patel KS, Hess C, Bodach ME, Tumialan LM, Oyesiku NM, Patil CG, Litvack Z, Zada G, Aghi MK. Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on Preoperative Imaging Assessment of Patients With Suspected Nonfunctioning Pituitary Adenomas. Neurosurgery. 2016 10; 79(4):E524-6.
Garzon MC, Epstein LG, Heyer GL, Frommelt PC, Orbach DB, Baylis AL, Blei F, Burrows PE, Chamlin SL, Chun RH, Hess CP, Joachim S, Johnson K, Kim W, Liang MG, Maheshwari M, McCoy GN, Metry DW, Monrad PA, Pope E, Powell J, Shwayder TA, Siegel DH, Tollefson MM, Vadivelu S, Lew SM, Frieden IJ, Drolet BA. PHACE Syndrome: Consensus-Derived Diagnosis and Care Recommendations. J Pediatr. 2016 Nov; 178:24-33.e2.
Bonham LW, Geier EG, Fan CC, Leong JK, Besser L, Kukull WA, Kornak J, Andreassen OA, Schellenberg GD, Rosen HJ, Dillon WP, Hess CP, Miller BL, Dale AM, Desikan RS, Yokoyama JS. Age-dependent effects of APOE e4 in preclinical Alzheimer's disease. Ann Clin Transl Neurol. 2016 Sep; 3(9):668-77.
Mamlouk MD, Hess CP. Arterial spin-labeled perfusion for vascular anomalies in the pediatric head and neck. Clin Imaging. 2016 Sep-Oct; 40(5):1040-6.
Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH, Andreassen OA, Dale AM, Desikan RS. Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease. JAMA Neurol. 2016 Jun 01; 73(6):691-7.
Kansagra AP, Mabray MC, Ferriero DM, Barkovich AJ, Xu D, Hess CP. Microstructural maturation of white matter tracts in encephalopathic neonates. Clin Imaging. 2016 Sep-Oct; 40(5):1009-13.
Kim H, Lepage C, Maheshwary R, Jeon S, Evans AC, Hess CP, Barkovich AJ, Xu D. NEOCIVET: Towards accurate morphometry of neonatal gyrification and clinical applications in preterm newborns. Neuroimage. 2016 Sep; 138:28-42.
Pekmezci M, Nelson J, Su H, Hess C, Lawton MT, Sonmez M, Young WL, Kim H, Tihan T. Morphometric characterization of brain arteriovenous malformations for clinical and radiological studies to identify silent intralesional microhemorrhages. Clin Neuropathol. 2016 May-Jun; 35(3):114-21.
Oza VS, Feigenbaum DF, Jacquot C, Hess CP, Siegel D, Frieden IJ. Fetal Alcohol Exposure and PHACE Syndrome: A Case and Autopsy Report. Pediatr Dermatol. 2016 May; 33(3):e179-e183.
Zhu C, Haraldsson H, Tian B, Meisel K, Ko N, Lawton M, Grinstead J, Ahn S, Laub G, Hess C, Saloner D. High resolution imaging of the intracranial vessel wall at 3 and 7 T using 3D fast spin echo MRI. MAGMA. 2016 Jun; 29(3):559-70.
Oza VS, Mamlouk MD, Hess CP, Mathes EF, Frieden IJ. Role of Sirolimus in Advanced Kaposiform Hemangioendothelioma. Pediatr Dermatol. 2016 Mar-Apr; 33(2):e88-92.
Frey KA, Lodge MA, Meltzer CC, Peller PJ, Wong TZ, Hess CP, Petrella JR, Sair HI, Subramaniam RM. ACR-ASNR Practice Parameter for Brain PET/CT Imaging Dementia. Clin Nucl Med. 2016 Feb; 41(2):118-25.
Talbott JF, Nout-Lomas YS, Wendland MF, Mukherjee P, Huie JR, Hess CP, Mabray MC, Bresnahan JC, Beattie MS. Diffusion-Weighted Magnetic Resonance Imaging Characterization of White Matter Injury Produced by Axon-Sparing Demyelination and Severe Contusion Spinal Cord Injury in Rats. J Neurotrauma. 2016 05 15; 33(10):929-42.
Schmied L, Terszowski G, Gonzalez A, Schmitter K, Hirsch HH, Garzoni C, van Delden C, Boggian K, Mueller NJ, Berger C, Villard J, Manuel O, Meylan P, Hess C, Stern M. Protection From Varicella Zoster in Solid Organ Transplant Recipients Carrying Killer Cell Immunoglobulin-Like Receptor B Haplotypes. Transplantation. 2015 Dec; 99(12):2651-5.
Kim H, Gano D, Ho ML, Guo XM, Unzueta A, Hess C, Ferriero DM, Xu D, Barkovich AJ. Hindbrain regional growth in preterm newborns and its impairment in relation to brain injury. Hum Brain Mapp. 2016 Feb; 37(2):678-88.
Antonov NK, Spence-Shishido A, Marathe KS, Tlougan B, Kazim M, Sultan S, Hess CP, Morel KD, Frieden IJ, Garzon MC. Orbital Hemangioma with Intracranial Vascular Anomalies and Hemangiomas: A New Presentation of PHACE Syndrome? Pediatr Dermatol. 2015 Nov-Dec; 32(6):e267-72.
Wen Q, Kelley DA, Banerjee S, Lupo JM, Chang SM, Xu D, Hess CP, Nelson SJ. Clinically feasible NODDI characterization of glioma using multiband EPI at 7 T. Neuroimage Clin. 2015; 9:291-9.
Gardner RC, Possin KL, Hess CP, Huang EJ, Grinberg LT, Nolan AL, Cohn-Sheehy BI, Ghosh PM, Lanata S, Merrilees J, Kramer JH, Berger MS, Miller BL, Yaffe K, Rabinovici GD. Evaluating and treating neurobehavioral symptoms in professional American football players: Lessons from a case series. Neurol Clin Pract. 2015 Aug; 5(4):285-295.
Gardner RC, Hess CP, Brus-Ramer M, Possin KL, Cohn-Sheehy BI, Kramer JH, Berger MS, Yaffe K, Miller B, Rabinovici GD. Cavum Septum Pellucidum in Retired American Pro-Football Players. J Neurotrauma. 2016 Jan 01; 33(1):157-61.
Koo KS, Dowd CF, Mathes EF, Rosbe KW, Hoffman WY, Frieden IJ, Hess CP. MRI phenotypes of localized intravascular coagulopathy in venous malformations. Pediatr Radiol. 2015 Oct; 45(11):1690-5.
Wilson SM, Lam D, Babiak MC, Perry DW, Shih T, Hess CP, Berger MS, Chang EF. Transient aphasias after left hemisphere resective surgery. J Neurosurg. 2015 Sep; 123(3):581-93.
Abla AA, Nelson J, Kim H, Hess CP, Tihan T, Lawton MT. Silent arteriovenous malformation hemorrhage and the recognition of "unruptured" arteriovenous malformation patients who benefit from surgical intervention. Neurosurgery. 2015 May; 76(5):592-600; discussion 600.
Patel AS, Schulman JM, Ruben BS, Hoffman WY, Dowd CF, Frieden IJ, Hess CP. Atypical MRI features in soft-tissue arteriovenous malformation: a novel imaging appearance with radiologic-pathologic correlation. Pediatr Radiol. 2015 Sep; 45(10):1515-21.
Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen CH, Karow DS, Brewer JB, Hess CP, Williams J, Sims R, O'Donovan MC, Choi SH, Bis JC, Ikram MA, Gudnason V, DeStefano AL, van der Lee SJ, Psaty BM, van Duijn CM, Launer L, Seshadri S, Pericak-Vance MA, Mayeux R, Haines JL, Farrer LA, Hardy J, Ulstein ID, Aarsland D, Fladby T, White LR, Sando SB, Rongve A, Witoelar A, Djurovic S, Hyman BT, Snaedal J, Steinberg S, Stefansson H, Stefansson K, Schellenberg GD, Andreassen OA, Dale AM. Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease. Circulation. 2015 Jun 09; 131(23):2061-2069.
Mamlouk MD, Saket RR, Hess CP, Dillon WP. Adding value in radiology: establishing a designated quality control radiologist in daily workflow. J Am Coll Radiol. 2015 Aug; 12(8):838-41.
Chen Y, Tymofiyeva O, Hess CP, Xu D. Effects of rejecting diffusion directions on tensor-derived parameters. Neuroimage. 2015 Apr 01; 109:160-70.
Bian W, Banerjee S, Kelly DA, Hess CP, Larson PE, Chang SM, Nelson SJ, Lupo JM. Simultaneous imaging of radiation-induced cerebral microbleeds, arteries and veins, using a multiple gradient echo sequence at 7 Tesla. J Magn Reson Imaging. 2015 Aug; 42(2):269-79.
Osorio JA, Benet A, Hess CP, McDermott MW, Abla AA. Primary vertebral artery reanastomosis during retrosigmoid skull base approach following iatrogenic near-transection with monopolar electrocautery. Neurosurgery. 2014 Dec; 10 Suppl 4:631-9.
Alexandrescu S, Orengo JP, Toossi S, Perry A, Treseler P, Hess C, Margeta M. CNS intravascular large cell lymphoma in a patient with autoimmune hemolytic anemia. Neuropathology. 2015 Apr; 35(2):170-4.
Caverzasi E, Mandelli ML, DeArmond SJ, Hess CP, Vitali P, Papinutto N, Oehler A, Miller BL, Lobach IV, Bastianello S, Geschwind MD, Henry RG. White matter involvement in sporadic Creutzfeldt-Jakob disease. Brain. 2014 Dec; 137(Pt 12):3339-54.
Gastelum E, Sear K, Hills N, Roddy E, Randazzo D, Chettout N, Hess C, Cotter J, Haas-Kogan DA, Fullerton H, Mueller S. Rates and characteristics of radiographically detected intracerebral cavernous malformations after cranial radiation therapy in pediatric cancer patients. J Child Neurol. 2015 Jun; 30(7):842-849.
Nguyen JT, Koerper MA, Hess CP, Dowd CF, Hoffman WY, Dickman M, Frieden IJ. Aspirin therapy in venous malformation: a retrospective cohort study of benefits, side effects, and patient experiences. Pediatr Dermatol. 2014 Sep-Oct; 31(5):556-60.
Tymofiyeva O, Ziv E, Barkovich AJ, Hess CP, Xu D. Brain without anatomy: construction and comparison of fully network-driven structural MRI connectomes. PLoS One. 2014; 9(5):e96196.
Trattner S, Pearson GDN, Chin C, Cody DD, Gupta R, Hess CP, Kalra MK, Kofler JM, Krishnam MS, Einstein AJ. Standardization and optimization of CT protocols to achieve low dose. J Am Coll Radiol. 2014 Mar; 11(3):271-278.
Graves J, Kraus V, Soares BP, Hess CP, Waubant E. Longitudinally extensive optic neuritis in pediatric patients. J Child Neurol. 2015 Jan; 30(1):120-3.
Desikan RS, Thompson WK, Holland D, Hess CP, Brewer JB, Zetterberg H, Blennow K, Andreassen OA, McEvoy LK, Hyman BT, Dale AM. The role of clusterin in amyloid-ß-associated neurodegeneration. JAMA Neurol. 2014 Feb; 71(2):180-7.
Guo Y, Tihan T, Kim H, Hess C, Lawton MT, Young WL, Zhao Y, Su H. Distinctive distribution of lymphocytes in unruptured and previously untreated brain arteriovenous malformation. Neuroimmunol Neuroinflamm. 2014; 1(3):147-152.
You SC, Geschwind MD, Sha SJ, Apple A, Satris G, Wood KA, Johnson ET, Gooblar J, Feuerstein JS, Finkbeiner S, Kang GA, Miller BL, Hess CP, Kramer JH, Possin KL. Executive functions in premanifest Huntington's disease. Mov Disord. 2014 Mar; 29(3):405-9.
Hess CP, Christine CW, Apple AC, Dillon WP, Aminoff MJ. Changes in the thalamus in atypical parkinsonism detected using shape analysis and diffusion tensor imaging. AJNR Am J Neuroradiol. 2014 May; 35(5):897-903.
Bian W, Hess CP, Chang SM, Nelson SJ, Lupo JM. Susceptibility-weighted MR imaging of radiation therapy-induced cerebral microbleeds in patients with glioma: a comparison between 3T and 7T. Neuroradiology. 2014 Feb; 56(2):91-6.
Ziv E, Tymofiyeva O, Ferriero DM, Barkovich AJ, Hess CP, Xu D. A machine learning approach to automated structural network analysis: application to neonatal encephalopathy. PLoS One. 2013; 8(11):e78824.
Desikan RS, Thompson WK, Holland D, Hess CP, Brewer JB, Zetterberg H, Blennow K, Andreassen OA, McEvoy LK, Hyman BT, Dale AM. Heart fatty acid binding protein and Aß-associated Alzheimer's neurodegeneration. Mol Neurodegener. 2013 Oct 02; 8:39.
Wu YW, Hess CP, Singhal NS, Groden C, Toro C. Idiopathic basal ganglia calcifications: an atypical presentation of PKAN. Pediatr Neurol. 2013 Nov; 49(5):351-4.
Vogel SA, Hess CP, Dowd CF, Hoffman WY, Kane AJ, Rajaii R, Frieden IJ. Early versus later presentations of venous malformations: where and why? Pediatr Dermatol. 2013 Sep-Oct; 30(5):534-40.
Tymofiyeva O, Hess CP, Ziv E, Lee PN, Glass HC, Ferriero DM, Barkovich AJ, Xu D. A DTI-based template-free cortical connectome study of brain maturation. PLoS One. 2013; 8(5):e63310.
Bian W, Hess CP, Chang SM, Nelson SJ, Lupo JM. Computer-aided detection of radiation-induced cerebral microbleeds on susceptibility-weighted MR images. Neuroimage Clin. 2013; 2:282-90.
Karampinos DC, Melkus G, Shepherd TM, Banerjee S, Saritas EU, Shankaranarayanan A, Hess CP, Link TM, Dillon WP, Majumdar S. Diffusion tensor imaging and T2 relaxometry of bilateral lumbar nerve roots: feasibility of in-plane imaging. NMR Biomed. 2013 Jun; 26(6):630-7.
Hegde M, Santos-Sanchez C, Hess CP, Kabir AA, Garcia PA. Seizure exacerbation in two patients with focal epilepsy following marijuana cessation. Epilepsy Behav. 2012 Dec; 25(4):563-6.
Metry D, Frieden IJ, Hess C, Siegel D, Maheshwari M, Baselga E, Chamlin S, Garzon M, Mancini AJ, Powell J, Drolet BA. Propranolol use in PHACE syndrome with cervical and intracranial arterial anomalies: collective experience in 32 infants. Pediatr Dermatol. 2013 Jan-Feb; 30(1):71-89.
West TW, Hess C, Cree BA. Acute transverse myelitis: demyelinating, inflammatory, and infectious myelopathies. Semin Neurol. 2012 Apr; 32(2):97-113.
Hess CP, Dillon WP. Imaging the pituitary and parasellar region. Neurosurg Clin N Am. 2012 Oct; 23(4):529-42.
Tangtiphaiboontana J, Hess CP, Bayer M, Drolet BA, Nassif LM, Metry DW, Barkovich AJ, Frieden IJ, Fullerton HJ. Neurodevelopmental abnormalities in children with PHACE syndrome. J Child Neurol. 2013 May; 28(5):608-14.
Hasan DM, Amans M, Tihan T, Hess C, Guo Y, Cha S, Su H, Martin AJ, Lawton MT, Neuwelt EA, Saloner DA, Young WL. Ferumoxytol-enhanced MRI to Image Inflammation within Human Brain Arteriovenous Malformations: A Pilot Investigation. Transl Stroke Res. 2012 Jul; 3(Suppl 1):166-73.
Siegel DH, Tefft KA, Kelly T, Johnson C, Metry D, Burrows P, Pope E, Cordisco M, Holland KE, Maheshwari M, Keith P, Garzon M, Hess C, Frieden IJ, Fullerton HJ, Drolet BA. Stroke in children with posterior fossa brain malformations, hemangiomas, arterial anomalies, coarctation of the aorta and cardiac defects, and eye abnormalities (PHACE) syndrome: a systematic review of the literature. Stroke. 2012 Jun; 43(6):1672-4.
Tymofiyeva O, Hess CP, Ziv E, Tian N, Bonifacio SL, McQuillen PS, Ferriero DM, Barkovich AJ, Xu D. Towards the "baby connectome": mapping the structural connectivity of the newborn brain. PLoS One. 2012; 7(2):e31029.
Guo Y, Saunders T, Su H, Kim H, Akkoc D, Saloner DA, Hetts SW, Hess C, Lawton MT, Bollen AW, Pourmohamad T, McCulloch CE, Tihan T, Young WL. Silent intralesional microhemorrhage as a risk factor for brain arteriovenous malformation rupture. Stroke. 2012 May; 43(5):1240-6.
Holbro A, Jauch A, Lardinois D, Tzankov A, Dirnhofer S, Hess C. High prevalence of infections and autoimmunity in patients with thymoma. Hum Immunol. 2012 Mar; 73(3):287-90.
Lupo JM, Li Y, Hess CP, Nelson SJ. Advances in ultra-high field MRI for the clinical management of patients with brain tumors. Curr Opin Neurol. 2011 Dec; 24(6):605-15.
Lupo JM, Chuang CF, Chang SM, Barani IJ, Jimenez B, Hess CP, Nelson SJ. 7-Tesla susceptibility-weighted imaging to assess the effects of radiotherapy on normal-appearing brain in patients with glioma. Int J Radiat Oncol Biol Phys. 2012 Mar 01; 82(3):e493-500.
Nabatian AS, Milgraum SS, Hess CP, Mancini AJ, Krol A, Frieden IJ. PHACE without face? Infantile hemangiomas of the upper body region with minimal or absent facial hemangiomas and associated structural malformations. Pediatr Dermatol. 2011 May-Jun; 28(3):235-41.
Brandon K, Burrows P, Hess C, Metry D. Arteriovenous malformation: a rare manifestation of PHACE syndrome. Pediatr Dermatol. 2011 Mar-Apr; 28(2):180-4.
Hess CP, Mukherjee P, Barbaro NM. Epileptic foci. J Neurosurg. 2011 Jun; 114(6):1691-2; discussion 1692.
Hess CP, Barkovich AJ. Seizures: emergency neuroimaging. Neuroimaging Clin N Am. 2010 Nov; 20(4):619-37.
Rosbe KW, Hess CP, Dowd CF, Frieden IJ. Masseteric venous malformations: diagnosis, treatment, and outcomes. Otolaryngol Head Neck Surg. 2010 Dec; 143(6):779-83.
Desikan RS, Sabuncu MR, Schmansky NJ, Reuter M, Cabral HJ, Hess CP, Weiner MW, Biffi A, Anderson CD, Rosand J, Salat DH, Kemper TL, Dale AM, Sperling RA, Fischl B. Selective disruption of the cerebral neocortex in Alzheimer's disease. PLoS One. 2010 Sep 23; 5(9):e12853.
von Morze C, Kelley DA, Shepherd TM, Banerjee S, Xu D, Hess CP. Reduced field-of-view diffusion-weighted imaging of the brain at 7 T. Magn Reson Imaging. 2010 Dec; 28(10):1541-5.
Koontz NA, Hess CP. AJR teaching file: brain tumor in a patient with familial adenomatous polyposis. AJR Am J Roentgenol. 2010 Sep; 195(3 Suppl):S25-8.
Burnett MM, Hess CP, Roberts JP, Bass NM, Douglas VC, Josephson SA. Presentation of reversible posterior leukoencephalopathy syndrome in patients on calcineurin inhibitors. Clin Neurol Neurosurg. 2010 Dec; 112(10):886-91.
Hess CP, Fullerton HJ, Metry DW, Drolet BA, Siegel DH, Auguste KI, Gupta N, Haggstrom AN, Dowd CF, Frieden IJ, Barkovich AJ. Cervical and intracranial arterial anomalies in 70 patients with PHACE syndrome. AJNR Am J Neuroradiol. 2010 Nov; 31(10):1980-6.
Raj A, Hess C, Mukherjee P. Spatial HARDI: improved visualization of complex white matter architecture with Bayesian spatial regularization. Neuroimage. 2011 Jan 01; 54(1):396-409.
Desikan RS, Cabral HJ, Settecase F, Hess CP, Dillon WP, Glastonbury CM, Weiner MW, Schmansky NJ, Salat DH, Fischl B. Automated MRI measures predict progression to Alzheimer's disease. Neurobiol Aging. 2010 Aug; 31(8):1364-74.
Toossi S, Hess CP, Hills NK, Josephson SA. Neurovascular complications of cocaine use at a tertiary stroke center. J Stroke Cerebrovasc Dis. 2010 Jul-Aug; 19(4):273-8.
Stern M, Opelz G, Döhler B, Hess C. Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma. Blood. 2010 May 13; 115(19):3960-5.
Metry D, Heyer G, Hess C, Garzon M, Haggstrom A, Frommelt P, Adams D, Siegel D, Hall K, Powell J, Frieden I, Drolet B. Consensus Statement on Diagnostic Criteria for PHACE Syndrome. Pediatrics. 2009 Nov; 124(5):1447-56.
Cantoni N, Meyer P, Katan M, Kappos L, Hess C, Daikeler T. A confusing patient's history: small or large vessel vasculitis? Rheumatol Int. 2010 Nov; 30(12):1681-3.
Metry DW, Garzon MC, Drolet BA, Frommelt P, Haggstrom A, Hall J, Hess CP, Heyer GL, Siegel D, Baselga E, Katowitz W, Levy ML, Mancini A, Maronn ML, Phung T, Pope E, Sun G, Frieden IJ. PHACE syndrome: current knowledge, future directions. Pediatr Dermatol. 2009 Jul-Aug; 26(4):381-98.
Desikan RS, Cabral HJ, Hess CP, Dillon WP, Glastonbury CM, Weiner MW, Schmansky NJ, Greve DN, Salat DH, Buckner RL, Fischl B. Automated MRI measures identify individuals with mild cognitive impairment and Alzheimer's disease. Brain. 2009 Aug; 132(Pt 8):2048-57.
Hess CP. Update on diffusion tensor imaging in Alzheimer's disease. Magn Reson Imaging Clin N Am. 2009 May; 17(2):215-24.
Purcell DD, Hess CP, Durack JC, Breiman RS. Recording, editing, archiving, and distributing radiology lectures: a streamlined approach. Radiographics. 2007 Nov-Dec; 27(6):1839-44.
Hess CP, Mukherjee P. Visualizing white matter pathways in the living human brain: diffusion tensor imaging and beyond. Neuroimaging Clin N Am. 2007 Nov; 17(4):407-26, vii.
von Morze C, Xu D, Purcell DD, Hess CP, Mukherjee P, Saloner D, Kelley DA, Vigneron DB. Intracranial time-of-flight MR angiography at 7T with comparison to 3T. J Magn Reson Imaging. 2007 Oct; 26(4):900-4.
Berman JI, Chung S, Mukherjee P, Hess CP, Han ET, Henry RG. Probabilistic streamline q-ball tractography using the residual bootstrap. Neuroimage. 2008 Jan 01; 39(1):215-22.
Mukherjee P, Hess CP, Xu D, Han ET, Kelley DA, Vigneron DB. Development and initial evaluation of 7-T q-ball imaging of the human brain. Magn Reson Imaging. 2008 Feb; 26(2):171-80.
Gasser O, Bihl FK, Wolbers M, Loggi E, Steffen I, Hirsch HH, Günthard HF, Walker BD, Brander C, Battegay M, Hess C. HIV patients developing primary CNS lymphoma lack EBV-specific CD4+ T cell function irrespective of absolute CD4+ T cell counts. PLoS Med. 2007 Mar 27; 4(3):e96.
Hess CP, Mukherjee P, Han ET, Xu D, Vigneron DB. Q-ball reconstruction of multimodal fiber orientations using the spherical harmonic basis. Magn Reson Med. 2006 Jul; 56(1):104-17.