Amy Pradhan, MS, MPH

Director of Academic Affairs
Site Director - Parnassus
Dir of Academic Aff & Ste Mgnt

Biography

Amy Pradhan started her career at the University of California, San Francisco (UCSF) in 2008, and joined the Department of Radiology and Biomedical Imaging in 2014. As the Director of Academic Affairs, Amy partners with the Department’s Vice-Chair for Academic Affair and other faculty & staff leaders to coordinate five main components: Faculty Merits & Promotions, Faculty Annual Renewals, Faculty Compensation, Faculty Recruitment & Hiring process, and New Faculty On-boarding. Amy and her academic affairs team manage the department's faculty appointment issues and Academic HR concerns.

Amy also is the Site Manager for the department's Parnassus campus, and she manages several sections' administrative staff and oversees site operations.

SERVICE:
Alumni, UCSF SOM Leadership & Development Program - Graduated 2016
Member, UCSF Department of Radiology, Faculty Diversity & Inclusion Committee- 2015 to Present
Member, UCSF Department of Radiology Staff Meeting Committee - 2014 to Present
Participant, Harvard-Macy Institute, Technology in Health Care Education Program - 2013

Education

2019 - Diversity, Equity, and Inclusion Champion Training, University of California, San Francisco
2013 - Technology in Health Care Education Program, Harvard-Macy Institute
MPH, 2013 - Public Health, San Jose State University
MS, 2008 - Health Care Administration, California State University, East Bay
2008 - Minority Training Program in Cancer Control Research, University of California, San Francisco
BS, 2005 - Psychology, University of California, Davis

Publications

Moye LS, Siegersma K, Dripps I, Witkowski W, Mangutov E, Wang D, Scherrer G, Pradhan AA. Delta opioid receptor regulation of calcitonin gene-related peptide dynamics in the trigeminal complex. Pain. 2021 Aug 01; 162(8):2297-2308.
Bertels Z, Singh H, Dripps I, Siegersma K, Tipton AF, Witkowski WD, Sheets Z, Shah P, Conway C, Mangutov E, Ao M, Petukhova V, Karumudi B, Petukhov PA, Baca SM, Rasenick MM, Pradhan AA. Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition. Elife. 2021 Apr 15; 10.
Bertels Z, Witkowski WD, Asif S, Siegersma K, van Rijn RM, Pradhan AA. A non-convulsant delta-opioid receptor agonist, KNT-127, reduces cortical spreading depression and nitroglycerin-induced allodynia. Headache. 2021 Jan; 61(1):170-178.
Dripps IJ, Bertels Z, Moye LS, Tipton AF, Siegersma K, Baca SM, Kieffer BL, Pradhan AA. Forebrain delta opioid receptors regulate the response of delta agonist in models of migraine and opioid-induced hyperalgesia. Sci Rep. 2020 10 19; 10(1):17629.
Saengjaroentham C, Strother LC, Dripps I, Sultan Jabir MR, Pradhan A, Goadsby PJ, Holland PR. Differential medication overuse risk of novel anti-migraine therapeutics. Brain. 2020 09 01; 143(9):2681-2688.
Parker KE, Sugiarto E, Taylor AMW, Pradhan AA, Al-Hasani R. Pain, Motivation, Migraine, and the Microbiome: New Frontiers for Opioid Systems and Disease. Mol Pharmacol. 2020 10; 98(4):433-444.
Targowska-Duda KM, Ozawa A, Bertels Z, Cippitelli A, Marcus JL, Mielke-Maday HK, Zribi G, Rainey AN, Kieffer BL, Pradhan AA, Toll L. NOP receptor agonist attenuates nitroglycerin-induced migraine-like symptoms in mice. Neuropharmacology. 2020 06 15; 170:108029.
Holton CM, Strother LC, Dripps I, Pradhan AA, Goadsby PJ, Holland PR. Acid-sensing ion channel 3 blockade inhibits durovascular and nitric oxide-mediated trigeminal pain. Br J Pharmacol. 2020 06; 177(11):2478-2486.
Anapindi KDB, Yang N, Romanova EV, Rubakhin SS, Tipton A, Dripps I, Sheets Z, Sweedler JV, Pradhan AA. PACAP and Other Neuropeptide Targets Link Chronic Migraine and Opioid-induced Hyperalgesia in Mouse Models. Mol Cell Proteomics. 2019 12; 18(12):2447-2458.
Pradhan AA, Tipton AF, Zhang H, Akbari A, Pandey SC. Effect of Histone Deacetylase Inhibitor on Ethanol Withdrawal-Induced Hyperalgesia in Rats. Int J Neuropsychopharmacol. 2019 08 01; 22(8):523-527.
Bertels Z, Pradhan AAA. Emerging Treatment Targets for Migraine and Other Headaches. Headache. 2019 07; 59 Suppl 2:50-65.
Zhang P, Moye LS, Southey BR, Dripps I, Sweedler JV, Pradhan A, Rodriguez-Zas SL. Opioid-Induced Hyperalgesia Is Associated with Dysregulation of Circadian Rhythm and Adaptive Immune Pathways in the Mouse Trigeminal Ganglia and Nucleus Accumbens. Mol Neurobiol. 2019 Dec; 56(12):7929-7949.
Jeong H, Moye LS, Southey BR, Hernandez AG, Dripps I, Romanova EV, Rubakhin SS, Sweedler JV, Pradhan AA, Rodriguez-Zas SL. Gene Network Dysregulation in the Trigeminal Ganglia and Nucleus Accumbens of a Model of Chronic Migraine-Associated Hyperalgesia. Front Syst Neurosci. 2018; 12:63.
Moye LS, Tipton AF, Dripps I, Sheets Z, Crombie A, Violin JD, Pradhan AA. Delta opioid receptor agonists are effective for multiple types of headache disorders. Neuropharmacology. 2019 04; 148:77-86.
Vicente-Sanchez A, Dripps IJ, Tipton AF, Akbari H, Akbari A, Jutkiewicz EM, Pradhan AA. Tolerance to high-internalizing d opioid receptor agonist is critically mediated by arrestin 2. Br J Pharmacol. 2018 07; 175(14):3050-3059.
Moye LS, Novack ML, Tipton AF, Krishnan H, Pandey SC, Pradhan AA. The development of a mouse model of mTBI-induced post-traumatic migraine, and identification of the delta opioid receptor as a novel therapeutic target. Cephalalgia. 2019 01; 39(1):77-90.
Pradhan AA, Bertels Z, Akerman S. Targeted Nitric Oxide Synthase Inhibitors for Migraine. Neurotherapeutics. 2018 04; 15(2):391-401.
Vicente-Sanchez A, Pradhan AA. Ligand-Directed Signaling at the Delta Opioid Receptor. Handb Exp Pharmacol. 2018; 247:73-85.
Ben Aissa M, Tipton AF, Bertels Z, Gandhi R, Moye LS, Novack M, Bennett BM, Wang Y, Litosh V, Lee SH, Gaisina IN, Thatcher GR, Pradhan AA. Soluble guanylyl cyclase is a critical regulator of migraine-associated pain. Cephalalgia. 2018 07; 38(8):1471-1484.
Moye LS, Pradhan AAA. Animal Model of Chronic Migraine-Associated Pain. Curr Protoc Neurosci. 2017 Jul 05; 80:9.60.1-9.60.9.
Shiwarski DJ, Tipton A, Giraldo MD, Schmidt BF, Gold MS, Pradhan AA, Puthenveedu MA. A PTEN-Regulated Checkpoint Controls Surface Delivery of d Opioid Receptors. J Neurosci. 2017 04 05; 37(14):3741-3752.
Moye LS, Pradhan AA. From blast to bench: A translational mini-review of posttraumatic headache. J Neurosci Res. 2017 06; 95(6):1347-1354.
Cahill CM, Walwyn W, Taylor AMW, Pradhan AAA, Evans CJ. Allostatic Mechanisms of Opioid Tolerance Beyond Desensitization and Downregulation. Trends Pharmacol Sci. 2016 11; 37(11):963-976.
Tipton AF, Tarash I, McGuire B, Charles A, Pradhan AA. The effects of acute and preventive migraine therapies in a mouse model of chronic migraine. Cephalalgia. 2016 Oct; 36(11):1048-1056.
Vicente-Sanchez A, Segura L, Pradhan AA. The delta opioid receptor tool box. Neuroscience. 2016 Dec 03; 338:145-159.
Charles A, Pradhan AA. Delta-opioid receptors as targets for migraine therapy. Curr Opin Neurol. 2016 06; 29(3):314-9.
Pradhan AA, Perroy J, Walwyn WM, Smith ML, Vicente-Sanchez A, Segura L, Bana A, Kieffer BL, Evans CJ. Agonist-Specific Recruitment of Arrestin Isoforms Differentially Modify Delta Opioid Receptor Function. J Neurosci. 2016 Mar 23; 36(12):3541-51.
Taylor AM, Castonguay A, Ghogha A, Vayssiere P, Pradhan AA, Xue L, Mehrabani S, Wu J, Levitt P, Olmstead MC, De Koninck Y, Evans CJ, Cahill CM. Neuroimmune Regulation of GABAergic Neurons Within the Ventral Tegmental Area During Withdrawal from Chronic Morphine. Neuropsychopharmacology. 2016 Mar; 41(4):949-59.
Bowman SL, Soohoo AL, Shiwarski DJ, Schulz S, Pradhan AA, Puthenveedu MA. Cell-autonomous regulation of Mu-opioid receptor recycling by substance P. Cell Rep. 2015 Mar 24; 10(11):1925-36.
Pradhan AA, Tawfik VL, Tipton AF, Scherrer G. In vivo techniques to investigate the internalization profile of opioid receptors. Methods Mol Biol. 2015; 1230:87-104.
Pradhan AA, Smith ML, Zyuzin J, Charles A. d-Opioid receptor agonists inhibit migraine-related hyperalgesia, aversive state and cortical spreading depression in mice. Br J Pharmacol. 2014 May; 171(9):2375-84.
Mittal N, Roberts K, Pal K, Bentolila LA, Fultz E, Minasyan A, Cahill C, Pradhan A, Conner D, DeFea K, Evans C, Walwyn W. Select G-protein-coupled receptors modulate agonist-induced signaling via a ROCK, LIMK, and ß-arrestin 1 pathway. Cell Rep. 2013 Nov 27; 5(4):1010-21.
Pradhan AA, Smith ML, McGuire B, Tarash I, Evans CJ, Charles A. Characterization of a novel model of chronic migraine. Pain. 2014 Feb; 155(2):269-274.
Erbs E, Pradhan AA, Matifas A, Kieffer BL, Massotte D. Evaluation of cre recombinase delivery in mammalian cells using baculovirus infection. J Biotechnol. 2013 Jul 20; 166(4):182-6.
Pradhan A, Smith M, McGuire B, Evans C, Walwyn W. Chronic inflammatory injury results in increased coupling of delta opioid receptors to voltage-gated Ca2+ channels. Mol Pain. 2013 Mar 04; 9:8.
Pradhan AA, Smith ML, Kieffer BL, Evans CJ. Ligand-directed signalling within the opioid receptor family. Br J Pharmacol. 2012 Nov; 167(5):960-9.
Pradhan AA, Befort K, Nozaki C, Gavériaux-Ruff C, Kieffer BL. The delta opioid receptor: an evolving target for the treatment of brain disorders. Trends Pharmacol Sci. 2011 Oct; 32(10):581-90.
Lam H, Maga M, Pradhan A, Evans CJ, Maidment NT, Hales TG, Walwyn W. Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking ß-arrestin 2. Mol Pain. 2011 Apr 12; 7:24.
Lutz PE, Pradhan AA, Goeldner C, Kieffer BL. Sequential and opposing alterations of 5-HT(1A) receptor function during withdrawal from chronic morphine. Eur Neuropsychopharmacol. 2011 Nov; 21(11):835-40.
Pradhan AA, Walwyn W, Nozaki C, Filliol D, Erbs E, Matifas A, Evans C, Kieffer BL. Ligand-directed trafficking of the d-opioid receptor in vivo: two paths toward analgesic tolerance. J Neurosci. 2010 Dec 08; 30(49):16459-68.
Pradhan AA, Yu XH, Laird JM. Modality of hyperalgesia tested, not type of nerve damage, predicts pharmacological sensitivity in rat models of neuropathic pain. Eur J Pain. 2010 May; 14(5):503-9.
Pradhan AA, Becker JA, Scherrer G, Tryoen-Toth P, Filliol D, Matifas A, Massotte D, Gavériaux-Ruff C, Kieffer BL. In vivo delta opioid receptor internalization controls behavioral effects of agonists. PLoS One. 2009; 4(5):e5425.
Ndong C, Pradhan A, Puma C, Morello JP, Hoffert C, Groblewski T, O'Donnell D, Laird JM. Role of rat sensory neuron-specific receptor (rSNSR1) in inflammatory pain: contribution of TRPV1 to SNSR signaling in the pain pathway. Pain. 2009 May; 143(1-2):130-7.
Pradhan AA, Clarke PB. Comparison between delta-opioid receptor functional response and autoradiographic labeling in rat brain and spinal cord. J Comp Neurol. 2005 Jan 24; 481(4):416-26.
Pradhan AA, Clarke PB. Pharmacologically selective block of mu opioid antinociception by peptide nucleic acid antisense in absence of detectable ex vivo knockdown. Eur J Pharmacol. 2005 Jan 04; 506(3):229-36.
Morinville A, Cahill CM, Aibak H, Rymar VV, Pradhan A, Hoffert C, Mennicken F, Stroh T, Sadikot AF, O'Donnell D, Clarke PB, Collier B, Henry JL, Vincent JP, Beaudet A. Morphine-induced changes in delta opioid receptor trafficking are linked to somatosensory processing in the rat spinal cord. J Neurosci. 2004 Jun 16; 24(24):5549-59.