How prevalent are polyps?
Colorectal CA
- Most (>95%) CRC arise in adenomatous polyps
Risk of Malignancy
- 5-9 mm 1%
- 10-20 mm 4-10%
- >20 mm 25-40%
- <10 mm polyp-invasive ca: 10 years
Adenomatous: Benign glandular tumor
Prevalence
- 25% of people by age 50
- 50-60% of people by age 80
- Villous=10x Tubular malignant potential