How prevalent are polyps?

Colorectal CA 

  • Most (>95%) CRC arise in adenomatous polyps

Risk of Malignancy

  • 5-9 mm 1%
  • 10-20 mm 4-10%
  • >20 mm 25-40%
  • <10 mm polyp-invasive ca: 10 years

Adenomatous: Benign glandular tumor

Prevalence

  • 25% of people by age 50
  • 50-60% of people by age 80
  • Villous=10x Tubular malignant potential 

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