Is CT colonography accurate?

ACRIN 6664: National CTC Trial (N Engl J Med 2008; 359:1207-1217)

• Multi-institutional (15 sites)-academic and private
• Feb 2005-Dec 2006
• ≥50 years asx, screening asymptomatic (without symptoms) patients
• 15 patients, 2531 patients
• Radiologist certification to read cases:
  • >500 cases already: 90% accuracy
  • <500 cases: 1 day training course +90% accuracy
  • Otherwise additional 20 cases for testing