International Hyperpolarized C-13 MRI Seminar

Date

February 17, 202202/17/2022 9:00am 02/17/2022 9:00am International Hyperpolarized C-13 MRI Seminar

View Flyer: https://ucsf.box.com/v/hmtrc-22-feb-seminar  

Join us with this Zoom 1-click Link: https://us02web.zoom.us/j/85169799890  

Sign up for Seminar Series Updates:  https://mailchi.mp/ucsf.edu/inthp-c13-mri-seminar 

3236 America/Los_Angeles public

Type

Seminar

Time Duration

8:00am – 9:00am

View Flyer: https://ucsf.box.com/v/hmtrc-22-feb-seminar  

Join us with this Zoom 1-click Link: https://us02web.zoom.us/j/85169799890  

Sign up for Seminar Series Updates:  https://mailchi.mp/ucsf.edu/inthp-c13-mri-seminar 

Speakers

Michael Ohliger, MD, PhD
Associate Professor of Radiology
HP Radiologist Leadership Committee
UCSF Department of Radiology & Biomedical Imaging

Michael Ohliger, MD, PhD, is an Associate Professor in Residence in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Dr. Ohliger obtained his PhD in Medical Physics from the Massachusetts Institute of Technology Harvard/MIT Division of Health Sciences and Technology in 2005, and he received his MD in Medicine from Harvard Medical School in 2007. He completed his residency in Diagnostic Radiology and fellowship training in Abdominal Imaging at UCSF. He joined the UCSF faculty in 2013.

Dr. Ohliger’s main research involves the development and clinical translation of new MRI techniques for the abdomen and pelvis, with a focus on molecular imaging of liver tumors, liver metabolism and liver injury. Current research projects involve using hyperpolarized carbon-13 MRI to image liver tumors as well as fatty liver disease. Dr. Ohliger also has a major research effort (together with Dr. David Wilson and Oren Rosenberg) developing novel methods for imaging bacterial injection.

Jeremy Gordon, PhD
Assistant Professor
TR&D1 Leader
HMTRC Executive Committee Member

UCSF Department of Radiology & Biomedical Imaging

Presentation 1: HP 13C MR Acquisition Developments Update

Charles Cunningham, PhD
Professor of Medical Biophysics
Senior Scientist at the Sunnybrook Research Institute
University of Toronto Department of Medical Biophysics

Presentation 2: Hyperpolarized 13C MRI of the Human Brain

Our lab is focused on making measurements and images using 13C-labelled metabolites, and studying how these change in disease. We also develop the required imaging methodology and hardware to perform this new form of MRI. To give metabolites a magnetic signal large enough to enable MRI, dynamic nuclear polarization (DNP) is applied in order to magnetize concentrated samples of a substrate, such as 13C-labeled pyruvate, and the resulting solution is injected in vivo.  We are interested in the metabolic characterization of damaged heart muscle in order to detect the early stages of heart failure and select therapies, as well as metabolic characterization of cancer as a possible method for staging and for measuring response to therapy.

Our group specializes in the development of new methodology and hardware for imaging 13C-labelled compounds in humans, and have used these to make the first metabolic images of the human heart.