“Improving the Treatment and Diagnosis of Bacterial Infection”
Date
Join the Department of Radiology and Biomedical Imaging for a lecture by Peter Tonge, PhD, “Improving the Treatment and Diagnosis of Bacterial Infection”. Research in the Tonge laboratory focuses on two major areas: (i) inhibitor discovery and the mechanism of drug action, and (ii) photoreceptor biophysics and biology. The Tonge laboratory designs and synthesizes inhibitors of enzyme drug targets involved in infectious diseases, cancer, and inflammation and uses PK/PD models coupled with positron emission tomography to explore the role of drug-target binding kinetics in drug activity at the cellular and whole organism level. The Tonge group also uses biophysical methods such as ultrafast spectroscopy coupled with site-specific protein modification to understand the mechanism of photoreceptor activation as a prelude to the development of optogenetic devices.
1521 America/Los_Angeles public
Type
Time Duration
Notes
https://ucsf.zoom.us/j/878859881
Meeting ID: 878 859 881
Telephone:
US: +1 669 900 6833
or +1 646 558 8656
or +1 877 853 5247 (Toll Free)
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Conference room system (H.323):
Dial: 162.255.37.11 (US West)
Dial: 162.255.36.11 (US East)
Join the Department of Radiology and Biomedical Imaging for a lecture by Peter Tonge, PhD, “Improving the Treatment and Diagnosis of Bacterial Infection”. Research in the Tonge laboratory focuses on two major areas: (i) inhibitor discovery and the mechanism of drug action, and (ii) photoreceptor biophysics and biology. The Tonge laboratory designs and synthesizes inhibitors of enzyme drug targets involved in infectious diseases, cancer, and inflammation and uses PK/PD models coupled with positron emission tomography to explore the role of drug-target binding kinetics in drug activity at the cellular and whole organism level. The Tonge group also uses biophysical methods such as ultrafast spectroscopy coupled with site-specific protein modification to understand the mechanism of photoreceptor activation as a prelude to the development of optogenetic devices.
Speakers
Peter Tonge, PhD obtained his B.Sc. and PhD degrees in biochemistry at the University of Birmingham and then moved to the National Research Council of Canada (NRC) in 1986 as a NATO-SERC postdoctoral fellow. After spells at NRC as a Research Associate and a Research Officer, followed by an appointment as a Staff Investigator at The Picower Institute for Medical Research, he joined the faculty at Stony Brook University in 1996 where he is currently a full Professor in the Department of Chemistry. He is also a Professor in the Department of Radiology (by courtesy) and Associate Editor for the American Chemical Society journal ACS Infectious Diseases.
He is currently the Co-Director of the NIH-funded Chemical Biology Training Program and Director of the Biomolecular Imaging Cluster. In addition he is Director of Infectious Diseases Research in the Institute for Chemical Biology & Drug Discovery (ICB&DD), and Director of the Translational Experimental Therapeutics Lab.