Neuroimaging

Understanding how neurodegenerative diseases disrupt the neural mechanisms of speaking can potentially lead to early disease detection and the development of novel therapeutic strategies for individuals with Alzheimer’s disease and other neurological disorders to maintain clearer and more intelligible speech.

Michael Weiner, MD, has reinvented his scientific focus more than once during his now half-century-long career. In 1980, Weiner was an Assistant Professor of Medicine (Nephrology) at Stanford, researching kidney metabolism at the Palo Alto Veterans Administration (VA) Medical Center.

UCSF researchers Harry (Shenghuan) Sun, Justin Torok, Daren Ma, and Ashish Raj, PhD, with Christopher Mezias of Cold Spring Harbor Laboratory, published “Spatial cell-type enrichment predicts mouse brain connectivity” in Cell Reports. 

Leighton Hinkley, PhD, first author of "Distinct neurophysiology during nonword repetition in logopenic and non-fluent variants of primary progressive aphasia" in Human Brain Mapping uses advanced imaging techniques to better understand neurodegenerative diseases. The research focused on Primary Progressive Aphasia (PPA), a condition within the Alzheimer's disease spectrum. In a recent interview Hinkley, a neuroscientist at the University of California, San Francisco (UCSF), explains his team's neuroimaging research.

Three UCSF Radiology researchers have received Surbeck Travel Awards to present their research at the International Society for Magnetic Resonance in Medicine (ISMRM) annual meeting. The recipients — Matthew Gibbons, PhD, Céline Taglang, PhD, and Pierre Nedelec — will travel to Toronto for the conference taking place June 3-8, 2023.

Each Surbeck Travel Award recipient will give an oral presentation at ISMRM

In a recent interview reflecting on ADNI’s significance in advancing Alzheimer’s research, Dr. Weiner observed that a major challenge for all clinical trials is that the trial participants do not fully represent the populations of people who need treatment.

A UCSF team that includes members of the Department of Radiology and Biomedical Imaging, is addressing new clinical and research neuro applications of High Intensity Focused Ultrasound (HIFU) and Low Intensity Focused Ultrasound (LIFU). A time will present their work on brain applications of HIFU and LIFU in an upcoming webinar on March 28 at noon PDT.  

Scientists at UCSF led by Olga Tymofiyeva, PhD conducted an individually randomized waitlist-controlled trial (RCT) with two objectives. The first was to test the feasibility of TARA, delivered partially over Zoom.

Do head knocks eventually lead to Alzheimer's disease? Michael Weiner, MD set out to examine this question in Vietnam veterans.