Jason Talbott, MD, PhD

Assistant Professor

Biography

Jason Talbott, MD, PhD, is an Assistant Professor in Residence in the Neuroradiology section in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco and Zuckerberg San Francisco General Hospital. He earned his MD and PhD degrees from the University of Louisville, Kentucky, in 2007. He completed a one-year internship in Internal Medicine from the California Pacific Medical Center in San Francisco. From 2008-2012, Dr. Talbott completed a four-year Diagnostic Radiology residency at UCSF, followed by a one-year fellowship in Neuroradiology from UCSF, in 2013.

In 2012, as a resident, Dr. Talbott received the Alexander Margulis Outstanding Resident Research Award and also served as a Chief Resident in the Department of Radiology at UCSF. Dr. Talbott currently serves as the Associate Program Director for the Radiology residency program and chairs the Residency Selection Committee.

Research interests include advanced spinal cord and peripheral nerve MR imaging techniques utilizing experimental animal models. In addition, as part of a multi-disciplinary clinical team at Zuckerberg San Francisco General Hospital, Dr. Talbott is active in multiple SCI trials. Dr. Talbott has published 29 peer-reviewed articles a book chapter and 4 review articles.

Expertise:
Neuroradiology

Specialty:
Spinal cord

Professional Interests:
Spinal cord and brain trauma

Education and Training:
• Medical School: University of Louisville, Kentucky
• Internship: California Pacific Medical Center, San Francisco - Internal Medicine
• Residency: University of California, San Francisco - Diagnostic Radiology
• Fellowship: University of California, San Francisco - Neuroradiology
• Doctor of Philosophy: University of Louisville, Kentucky
• American Board of Radiology, Certificate in Diagnostic Radiology
• California Certificate

Education

Neuroradiology Fellowship, 2013
Radiology and Biomedical Imaging, University of California, San Francisco
Residency, 2012 Radiology and Biomedical Imaging, University of California, San Francisco
Medicine Internship, 2008 Medicine, California Pacific Medical Center
MD/PhD, 2007 School of Medicine, University of Louisville
BS, 2000 Biology, Stanford University

Honors and Awards

Margulis Society Outstanding Resident Research Award, University of California, San Francisco, 2012
Chief Resident, University of Califonria, San Francisco, 2011-2012
Institutional National Research Service Award, NIH, 2010
Margulis Society Grant Awardee, University of California, San Francisco, 2010
Alpha Omega Alpha Honor Society, 2006
Speaker’s Award, International Society of Neurotransplantation and Repair, 2002

Publications

Haefeli J, Mabray MC, Whetstone WD, Dhall SS, Pan JZ, Upadhyayula P, Manley GT, Bresnahan JC, Beattie MS, Ferguson AR, Talbott JF. Multivariate Analysis of MRI Biomarkers for Predicting Neurologic Impairment in Cervical Spinal Cord Injury. AJNR Am J Neuroradiol. 2016 Dec 22.
McCoy DB, Talbott JF, Wilson M, Mamlouk M, Cohen-Adad J, Wilson M, Narvid J. MRI Atlas-Based Measurement of Spinal Cord Injury Predicts Outcome in Acute Flaccid Myelitis. AJNR. 2016.
McCoy DB, Talbott JF, Wilson M, Mamlouk M, Cohen-Adad J, Wilson M, Narvid J. MRI Atlas-Based Measurement of Spinal Cord Injury Predicts Outcome in Acute Flaccid Myelitis. AJNR Am J Neuroradiol. 2016 Dec 15.
Readdy WJ, Saigal R, Whetstone WD, Mefford AN, Ferguson AR, Talbott JF, Inoue T, Bresnahan JC, Beattie MS, Pan J, Manley GT, Dhall SS. Failure of Mean Arterial Pressure Goals to Improve Outcomes Following Penetrating Spinal Cord Injury. Neurosurgery. 2016 Nov; 79(5):708-714.
Mutch CA, Talbott JF, Gean A. Imaging Evaluation of Acute Traumatic Brain Injury. Neurosurg Clin N Am. 2016; 4(27):409-39.
Catapano JS, John Hawryluk GW, Whetstone W, Saigal R, Ferguson A, Talbott J, Bresnahan J, Dhall S, Pan J, Beattie M, Manley G. Higher Mean Arterial Pressure Values Correlate With Neurological Improvement in Patients With Initially Complete Spinal Cord Injuries. World Neurosurg. 2016 Aug 23.
Park I, Nelson SJ, Talbott JF. In Vivo Monitoring of Rat Spinal Cord Metabolism Using Hyperpolarized Carbon-13 MR Spectroscopic Imaging. AJNR Am J Neuroradiol. 2016 Aug 11.
Mutch CA, Talbott JF, Gean A. Imaging Evaluation of Acute Traumatic Brain Injury. Neurosurg Clin N Am. 2016 Oct; 27(4):409-39.
Burke JF, Yue JK, Ngwenya LB, Winkler EA, Talbott J, Pan J, Ferguson A, Beattie M, Bresnahan J, Haefeli J, Whetstone W, Suen C, Huang MC, Manley GT, Tarapore PE, Dhall SS. 182 Ultra-Early (<12 Hours) Decompression Improves Recovery After Spinal Cord Injury Compared to Early (12-24 Hours) Decompression. Neurosurgery. 2016 Aug; 63 Suppl 1:172.
Robbins NM, Shah V, Benedetti N, Talbott JF, Chin CT, Douglas VC. Magnetic resonance neurography in the diagnosis of neuropathies of the lumbosacral plexus: a pictorial review. Clin Imaging. 2016 Jul 11; 40(6):1118-1130.
Talbott JF, Narvid J, Chazen JL, Chin CT, Shah V. An Imaging-Based Approach to Spinal Cord Infection. Semin Ultrasound CT MR. 2016 Oct; 37(5):411-30.
Chazen JL, Talbott J, Singh JR. Optimal Noninvasive Imaging for Suspected Zygapophyseal (Facet)-Mediated Low Back Pain. PM R. 2016 Jun; 8(6):586-92.
Pandit P, Talbott JF, Pedoia V, Dillon W, Majumdar S. T1? and T2 -based characterization of regional variations in intervertebral discs to detect early degenerative changes. J Orthop Res. 2016 May 26.
Readdy WJ, Saigal R, Whetstone WD, Mefford A, Ferguson AR, Talbott JF, Inoue T, Bresnahan JC, Beattie MS, Pan J, Manley GT, Dhall SS. Failure of Mean Arterial Pressure Goals to Improve Outcomes Following Penetrating Spinal Cord Injury. Neurosurgery. 2016 May 3.
Mabray MC, Brus-Ramer M, Behr SC, Pampaloni MH, Majumdar S, Dillon WP, Talbott JF. (18)F-Sodium Fluoride PET-CT Hybrid Imaging of the Lumbar Facet Joints: Tracer Uptake and Degree of Correlation to CT-graded Arthropathy. World J Nucl Med. 2016 May-Aug; 15(2):85-90.
Phillips D, Dhall SS, Uzelac A, Talbott JF. Gunshot wound causing anterior spinal cord infarction due to injury to the artery of adamkiewicz. Spine J. 2016 Feb 15.
Talbott JF, Nout-Lomas YS, Wendland MF, Mukherjee P, Huie JR, Hess CP, Mabray MC, Bresnahan JC, Beattie MS. Diffusion-Weighted Magnetic Resonance Imaging Characterization of White Matter Injury Produced by Axon-Sparing Demyelination and Severe Contusion Spinal Cord Injury in Rats. J Neurotrauma. 2016 May 15; 33(10):929-42.
Mabray MC, Talbott JF, Whetstone WD, Dhall SS, Phillips DB, Pan JZ, Manley GT, Bresnahan JC, Beattie MS, Haefeli J, Ferguson AR. Multidimensional Analysis of Magnetic Resonance Imaging Predicts Early Impairment in Thoracic and Thoracolumbar Spinal Cord Injury. J Neurotrauma. 2016 May 15; 33(10):954-62.
Simon NG, Talbott J, Chin CT, Kliot M. Peripheral nerve imaging. Handb Clin Neurol. 2016; 136:811-26.
Kozak B, Talbott J, Uzelac A, Rehani B. Rosai-Dorfman Disease Isolated to the Thoracic Epidural Spine. J Radiol Case Rep. 2015 Nov; 9(11):6-16.
Talbott JF, Whetstone WD, Readdy WJ, Ferguson AR, Bresnahan JC, Saigal R, Hawryluk GW, Beattie MS, Mabray MC, Pan JZ, Manley GT, Dhall SS. The Brain and Spinal Injury Center score: a novel, simple, and reproducible method for assessing the severity of acute cervical spinal cord injury with axial T2-weighted MRI findings. J Neurosurg Spine. 2015; 4(23):495-504.
Narvid J, Rehani B, Talbott JF. Diagnostic Performance of Brain MRI in Immune Reconstitution Inflammatory Syndrome. J Neuroimaging. 2016 May; 26(3):303-8.
Hawryluk G, Whetstone W, Saigal R, Ferguson A, Talbott J, Bresnahan J, Dhall S, Pan J, Beattie M, Manley G. Mean Arterial Blood Pressure Correlates with Neurological Recovery after Human Spinal Cord Injury: Analysis of High Frequency Physiologic Data. J Neurotrauma. 2015 Dec 15; 32(24):1958-67.
Narvid J, Talbott JF, Glastonbury CM. The caverno-apical triangle: anatomic-pathological considerations and pictorial review. Clin Imaging. 2016 Jan-Feb; 40(1):23-32.
Readdy WJ, Whetstone WD, Ferguson AR, Talbott JF, Inoue T, Saigal R, Bresnahan JC, Beattie MS, Pan JZ, Manley GT, Dhall SS. Complications and outcomes of vasopressor usage in acute traumatic central cord syndrome. J Neurosurg Spine. 2015 Jul 31; 1-7.
Talbott JF, Whetstone WD, Readdy WJ, Ferguson AR, Bresnahan JC, Saigal R, Hawryluk GW, Beattie MS, Mabray MC, Pan JZ, Manley GT, Dhall SS. The Brain and Spinal Injury Center score: a novel, simple, and reproducible method for assessing the severity of acute cervical spinal cord injury with axial T2-weighted MRI findings. J Neurosurg Spine. 2015 Oct; 23(4):495-504.
Mabray MC, Datta S, Lillaney PV, Moore T, Gehrisch S, Talbott JF, Levitt MR, Ghodke BV, Larson PS, Cooke DL. Accuracy of flat panel detector CT with integrated navigational software with and without MR fusion for single-pass needle placement. J Neurointerv Surg. 2016 Jul; 8(7):731-5.
Mabray MC, Uzelac A, Talbott JF, Lin SC, Gean AD. Ex-PRESS glaucoma filter: an MRI compatible metallic orbital foreign body imaged at 1.5 and 3T. Clin Radiol. 2015 May; 70(5):e28-34.
Talbott JF, Gean A, Yuh EL, Stiver SI. Reply. AJNR Am J Neuroradiol. 2015 Mar; 36(3):E25.
Baud MO, Uzelac A, Jay CA, Talbott JF. CNS siderosis and orthostatic headache as a delayed complication of spinal surgery. Neurology. 2014 Nov 25; 83(22):2097-8.
Irvine KA, Ferguson AR, Mitchell KD, Beattie SB, Lin A, Stuck ED, Huie JR, Nielson JL, Talbott JF, Inoue T, Beattie MS, Bresnahan JC. The Irvine, Beatties, and Bresnahan (IBB) Forelimb Recovery Scale: An Assessment of Reliability and Validity. Front Neurol. 2014; 5:116.
Talbott JF, Gean A, Yuh EL, Stiver SI. Calvarial fracture patterns on CT imaging predict risk of a delayed epidural hematoma following decompressive craniectomy for traumatic brain injury. AJNR Am J Neuroradiol. 2014 Oct; 35(10):1930-5.
Chazen JL, Talbott JF, Lantos JE, Dillon WP. MR myelography for identification of spinal CSF leak in spontaneous intracranial hypotension. AJNR Am J Neuroradiol. 2014 Oct; 35(10):2007-12.
Chow H, Jung A, Talbott J, Lin AM, Daud AI, Coakley FV. Tumor fistulization associated with targeted therapy: computed tomographic findings and clinical consequences. J Comput Assist Tomogr. 2011 Jan-Feb; 35(1):86-90.
Talbott JF, Cao Q, Bertram J, Nkansah M, Benton RL, Lavik E, Whittemore SR. CNTF promotes the survival and differentiation of adult spinal cord-derived oligodendrocyte precursor cells in vitro but fails to promote remyelination in vivo. Exp Neurol. 2007 Mar; 204(1):485-9.
Talbott JF, Cao Q, Enzmann GU, Benton RL, Achim V, Cheng XX, Mills MD, Rao MS, Whittemore SR. Schwann cell-like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP-dependent. Glia. 2006 Aug 15; 54(3):147-59.
Enzmann GU, Benton RL, Talbott JF, Cao Q, Whittemore SR. Functional considerations of stem cell transplantation therapy for spinal cord repair. J Neurotrauma. 2006 Mar-Apr; 23(3-4):479-95.
Talbott JF, Loy DN, Liu Y, Qiu MS, Bunge MB, Rao MS, Whittemore SR. Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes. Exp Neurol. 2005 Mar; 192(1):11-24.
Loy DN, Sroufe AE, Pelt JL, Burke DA, Cao QL, Talbott JF, Whittemore SR. Serum biomarkers for experimental acute spinal cord injury: rapid elevation of neuron-specific enolase and S-100beta. Neurosurgery. 2005 Feb; 56(2):391-7; discussion 391-7.
Krouse ME, Talbott JF, Lee MM, Joo NS, Wine JJ. Acid and base secretion in the Calu-3 model of human serous cells. Am J Physiol Lung Cell Mol Physiol. 2004 Dec; 287(6):L1274-83.
Loy DN, Talbott JF, Onifer SM, Mills MD, Burke DA, Dennison JB, Fajardo LC, Magnuson DS, Whittemore SR. Both dorsal and ventral spinal cord pathways contribute to overground locomotion in the adult rat. Exp Neurol. 2002 Oct; 177(2):575-80.
Talbott JF, Gorti GK, Koch RJ. Midfacial osteomyelitis in a chronic cocaine abuser: a case report. Ear Nose Throat J. 2001 Oct; 80(10):738-40, 742-3.