Jason Hsu, PhD

Assistant Professor
Associate Researcher

Biography

Jung-Jiin Hsu, PhD, also known as Jason Hsu, is an Assistant Professor in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Dr. Hsu obtained his BSc in Physics from Tunghai University, Taiwan in 1988, and received his MSc in Physics from the National Taiwan University, Taiwan in 1991. He completed his PhD in Physics from the University of Pittsburgh in 2002, followed by a postdoctoral fellowship in Biomedical MRI at the Lucas Center for Imaging, Department of Radiology, Stanford University. He was appointed Research Assistant Professor in the Department of Radiology, University of Miami Miller School of Medicine in 2009. In September 2012, he was recruited to fill the current position at UCSF and has been affiliated with the Center for Imaging of Neurodegenerative Diseases at the San Francisco Veterans Affairs Medical Center.

Before starting a career in biomedical research, Dr. Hsu had published a number of first-authored papers in theoretical and computational physics. His current interests lie in the physical and biological basis of MRI for neuro-vascular and cerebral hemodynamic measurements. He has developed a novel MRI technique for the measurement of the MR longitudinal relaxation rate that reduces the time of the measurement from a few minutes required by conventional techniques to a few seconds. The speed makes the measurement of the longitudinal relaxation feasible for dynamic brain imaging, which is being developed for quantitative recording of the brain functional activity to facilitate use of MRI for CNS drug development.

Expertise:
Physics, NMR and MRI, Scientific Computing

Specialty:
NMR/MRI relaxometry, functional neuroimaging, MRI physiological measurement

Professional Interests:
Magnetic resonance physics, imaging instrumentation and experiment design, quantitative and functional MRI, physical and biological basis of MRI

Education and Training:
• Bachelor of Science: Tunghai University, Taiwan - Physics
• Masters of Science: National Taiwan University, Taiwan - Physics
• Doctor of Philosophy: University of Pittsburgh, Pennsylvania - Physics
• Postdoctoral Fellow: Lucas Center for Imaging, Stanford University - Biomedical MRI

Publications

J.-J. Hsu; K. T. Chung; K.-N. Huang. Term values of 1s2s2p 4Po for lithiumlike ions. Physical Review A 44, 5485–5491 (1991).
J.-J. Hsu; K. T. Chung; K.-N. Huang. 4Po series of lithium. Physical Review A 49, 4466–4472 (1994).
J.-J. Hsu; K. T. Chung. Electron affinities of 1s22s2p 3Po and 1s22p2 3P of beryllium. Physical Review A 52, R898–R901 (1995).
J.-J. Hsu; K. T. Chung. Binding energy and Auger electron energies of 1s2s2p3 6So of the beryllium anion. Journal of Physics B 28, L649–L653 (1995).
J.-J. Hsu; I. J. Lowe. Signal recovery in free induction decay imaging using a stimulated spin echo. Magnetic Resonance in Medicine 47, 409–414 (2002).
H. Yun; M. E. Patton; J. H. Garrett; G. K. Fedder; K. M. Frederick; J.-J. Hsu; I. J. Lowe; I. J. Oppenheim; P. J. Sides. Detection of free chloride in concrete by NMR. Cement and Concrete Research 34, 379–390 (2004).
J.-J. Hsu; I. J. Lowe. Spin–lattice relaxation and a fast T1-map acquisition method in MRI with transient-state magnetization. Journal of Magnetic Resonance 169, 270–278 (2004).
J.-J. Hsu; G. H. Glover. Mitigation of susceptibility-induced signal loss in neuroimaging using localized shim coils. Magnetic Resonance in Medicine 53, 243–248 (2005).
J.-J. Hsu; G. H. Glover. Rapid MRI method for mapping the longitudinal relaxation time. Journal of Magnetic Resonance 181, 98–106 (2006).
J.-J. Hsu; I. J. Lowe. Encoding to the longitudinal magnetization for MR imaging and flow velocity mapping. Journal of Magnetic Resonance 183, 41–49 (2006).
J.-J. Hsu; G. Zaharchuk; G. H. Glover. Rapid methods for concurrent measurement of the RF-pulse flip angle and the longitudinal relaxation time. Magnetic Resonance in Medicine 61, 1319–1325 (2009).
J.-J. Hsu; G. H. Glover; G. Zaharchuk. Optimizing saturation–recovery measurements of the longitudinal relaxation rate under time constraints. Magnetic Resonance in Medicine 62, 1202–1210 (2009).
J. P. Hamilton; G. H. Glover; J.-J. Hsu; R. F. Johnson; I. H. Gotlib. Modulation of subgenual anterior cingulate cortex activity with real-time neurofeedback. Human Brain Mapping 32, 22–31 (2011).