Elias Botvinick, MD

Professor Emeritus
PROF EMERITUS(WOS)
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Biography

Elias H. Botvinick, MD, is now retired and has been "called back". He now works 44% time, all devoted to clinical care, teaching and research in the Cardiovascular Division. Following is a summary of all affiliations, titles achieved, all, publications, funding, memberships and honors while actively working full-time in both the Cardiovascular division and the Nuclear Medicine Section of the Department of radiology.

A Professor in Residence, Co-Director of the Adult Cardiology Non-Invasive Laboratory, and Director of the Cardiac Stress Testing Laboratory at the University of California, San Francisco. Dr. Botvinick received his medical degree from New York University School of Medicine in 1967, and completed a residency in Medicine at Bellevue Hospital in New York, followed by a fellowship in Nuclear Medicine from UCSF in 1976.

Dr. Botvinick’s primary research interest has been scintigraphic methods. His research involves recent applications of the scintigraphic imaging agent indicates its ability to map the regional density of sympathetic nerves and support the hypothesis that an altered balance in the relationship of perfusion and innervation can increase vulnerability to life threatening arrhythmias. Overall, Dr. Botvinick’s research has been a collaborative effort to develop non-invasive graphic and imaging methods for the identification and evaluation of cardiac anatomy and pathophysiology, and apply them to the diagnosis, risk stratification and monitoring of clinical disease.

Dr. Botvinick has written 178 articles, 46 book chapters, 301 abstracts, with 8 significant publications.

Expertise:
Nuclear Medicine and Cardiology

Specialty:
Nuclear cardiology, scintigraphy, cardiovascular diseases

Professional Interests:
Nuclear medicine, nuclear cardiology, PET/CT, MRI, CT, cardiac cardiology, echo cardiology, nuclear magnetic resonance, cardiovascular imaging, stress testing, heart, myocardial perfusion, scintigraphy, coronary, synchrony, synchronization

Education and Training:
• Medical School: New York University School of Medicine, New York
• Internship: Bellevue Hospital, New York - Medicine
• Internship: United States Army, Hospital, Fort Riley
• Residency: Bellevue Hospital, New York - Medicine
• Fellowship: University of California, San Francisco - Nuclear Medicine
• New York State Medical License
• Controlled Substance Registration Certificate
• California State Medical
• Internal Medicine Boards
• Nuclear Medicine Boards
• Cardiovascular Boards
• Certified, Basic Cardiac Life Support
• Certified, Advanced Cardiac Life Support

Education

M.D., 1967 - School of Medicine, New York University
Clinical Fellowship, - School of Medicine, University of California, San Francisco
Residency, - School of Medicine - Cardiology, University of California, San Francisco

Honors and Awards

Best Doctor's in California, Cardiology & Nuclear Medicine, San Francisco Magazine, 2000
Founding Member ASNC, American Society of Nuclear Cardiology, 1998
Keynote Speaker, Graduation Nuclear Medicine Technology Training Program, 1994
Founder and First President of the Cardiovascular Council, Society of Nuclear Medicine, 1992
Recipient Herman H. Blumgart Lectureship Award, Society of Nuclear Medicine, 1991
Bronze Star Medal Award, Republic of Vietnam, United States Army, 1971
Nominated for UCSF Medical School Kaiser award for Excellence in Teaching, University of California, San Francisco School of Medicine

Publications

Shrestha UM, Sciammarella M, Pampaloni MH, Botvinick EH, Gullberg GT, DeMarco T, Seo Y. Assessment of late-term progression of cardiac allograft vasculopathy in patients with orthotopic heart transplantation using quantitative cardiac 82Rb PET. Int J Cardiovasc Imaging. 2021 Apr; 37(4):1461-1472.
Botvinick EH. The beginnings of ASNC. J Nucl Cardiol. 2019 Feb; 26(1):39-41.
Mitra D, Abdalah M, Boutchko R, Chang H, Shrestha U, Botvinick E, Seo Y, Gullberg GT. Comparison of sparse domain approaches for 4D SPECT dynamic image reconstruction. Med Phys. 2018 Oct; 45(10):4493-4509.
Sciammarella M, Shrestha UM, Seo Y, Gullberg GT, Botvinick EH. A combined static-dynamic single-dose imaging protocol to compare quantitative dynamic SPECT with static conventional SPECT. J Nucl Cardiol. 2019 06; 26(3):763-771.
Pampaloni MH, Shrestha UM, Sciammarella M, Seo Y, Gullberg GT, Botvinick EH. Noninvasive PET quantitative myocardial blood flow with regadenoson for assessing cardiac allograft vasculopathy in orthotopic heart transplantation patients. J Nucl Cardiol. 2017 08; 24(4):1134-1144.
Badhwar N, James J, Hoffmayer KS, O'Connell JW, Green D, De Marco T, Botvinick EH. Utility of Equilibrium Radionuclide Angiogram-Derived Measures of Dyssynchrony to Predict Outcomes in Heart Failure Patients Undergoing Cardiac Resynchronization Therapy. J Nucl Med. 2016 Dec; 57(12):1880-1886.
Shrestha U, Sciammarella M, Alhassen F, Yeghiazarians Y, Ellin J, Verdin E, Boyle A, Seo Y, Botvinick EH, Gullberg GT. Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation. J Nucl Cardiol. 2017 02; 24(1):268-277.
Shrestha UM, Seo Y, Botvinick EH, Gullberg GT. Image reconstruction in higher dimensions: myocardial perfusion imaging of tracer dynamics with cardiac motion due to deformation and respiration. Phys Med Biol. 2015 Nov 07; 60(21):8275-301.
Johnson CJ, Roberts JD, James JH, Hoffmayer KS, Badhwar N, Ku IA, Zhao S, Naeger DM, Rao RK, O'Connell JW, De Marco T, Botvinick EH, Scheinman MM. Comparison of radionuclide angiographic synchrony analysis to echocardiography and magnetic resonance imaging for the diagnosis of arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2015 Jun; 12(6):1268-75.
Pampaloni MH, Nazer B, Botvinick E. Erratum to: Isolated right ventricular cardiac sarcoidosis demonstrated by (18)FDG positron emission tomography. J Nucl Cardiol. 2015 Feb; 22(1):221.
Shrestha U, Botvinick EH, Yeghiazarians Y, Seo Y, Gullberg GT. Quantitative Signature of Coronary Steal in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT. IEEE Nucl Sci Symp Conf Rec (1997). 2014 Nov; 2014.
Hernandez Pampaloni M, Nazer B, Nazar B, Botvinick E. Isolated right ventricular cardiac sarcoidosis demonstrated by ¹⁸FDG positron emission tomography. J Nucl Cardiol. 2014 Jun; 21(3):652-4.
Botvinick EH, O'Connell JW, Badhwar N. Imaging synchrony. J Nucl Cardiol. 2009 Nov-Dec; 16(6):846-8.
del Romeral LM, Stillson C, Lesh M, Botvinick E. The variable functional effects of the pacing site in normal and scarred ventricles. J Nucl Cardiol. 2009 Nov-Dec; 16(6):904-13.
del Romeral LM, Stillson C, Lesh M, Dae M, Botvinick E. The relationship of myocardial contraction and electrical excitation--the correlation between scintigraphic phase image analysis and electrophysiologic mapping. J Nucl Cardiol. 2009 Sep-Oct; 16(5):792-800.
Bural GG, Torigian DA, Botvinick E, Houseni M, Basu S, Chen W, Alavi A. A pilot study of changes in (18)F-FDG uptake, calcification and global metabolic activity of the aorta with aging. Hell J Nucl Med. 2009 May-Aug; 12(2):123-8.
Botvinick EH. Current methods of pharmacologic stress testing and the potential advantages of new agents. J Nucl Med Technol. 2009 Mar; 37(1):14-25.
Botvinick E, Davis J, Dae M, O'Connell J, Schechtmann N, Abbott J, Morady F, Lanzer P, Iskikian J, Scheinman M. Localization of ventricular tachycardia exit site and subsequent contraction sequence and functional effects with bedside radionuclide angiography. JACC Cardiovasc Imaging. 2008 Sep; 1(5):605-13.
Chen W, Botvinick EH, Alavi A, Zhang Y, Yang S, Perini R, Zhuang H. Age-related decrease in cardiopulmonary adrenergic neuronal function in children as assessed by I-123 metaiodobenzylguanidine imaging. J Nucl Cardiol. 2008 Jan-Feb; 15(1):73-9.
Hansen CL, Goldstein RA, Akinboboye OO, Berman DS, Botvinick EH, Churchwell KB, Cooke CD, Corbett JR, Cullom SJ, Dahlberg ST, Druz RS, Ficaro EP, Galt JR, Garg RK, Germano G, Heller GV, Henzlova MJ, Hyun MC, Johnson LL, Mann A, McCallister BD, Quaife RA, Ruddy TD, Sundaram SN, Taillefer R, Ward RP, Mahmarian JJ, American Society of Nuclear Cardiology. Myocardial perfusion and function: single photon emission computed tomography. J Nucl Cardiol. 2007 Nov-Dec; 14(6):e39-60.
Botvinick EH, Perini R, Bural G, Chen W, Chryssikos T, Houseni M, Hernandez-Pampaloni M, Torigian DA, Alavi A. The aging of the heart and blood vessels: a consideration of anatomy and physiology in the era of computed tomography, magnetic resonance imaging, and positron emission tomographic imaging methods with special consideration of atherogenesis. Semin Nucl Med. 2007 Mar; 37(2):120-43.
Corbett JR, Akinboboye OO, Bacharach SL, Borer JS, Botvinick EH, DePuey EG, Ficaro EP, Hansen CL, Henzlova MJ, Van Kriekinge S, Quality Assurance Committee of the American Society of Nuclear Cardiology. Equilibrium radionuclide angiocardiography. J Nucl Cardiol. 2006 Nov; 13(6):e56-79.
Funk T, Kirch DL, Koss JE, Botvinick E, Hasegawa BH. A novel approach to multipinhole SPECT for myocardial perfusion imaging. J Nucl Med. 2006 Apr; 47(4):595-602.
O'Connell JW, Schreck C, Moles M, Badwar N, DeMarco T, Olgin J, Lee B, Tseng Z, Kumar U, Botvinick EH. A unique method by which to quantitate synchrony with equilibrium radionuclide angiography. J Nucl Cardiol. 2005 Jul-Aug; 12(4):441-50.
Heller GV, Bateman TM, Johnson LL, Cullom SJ, Case JA, Galt JR, Garcia EV, Haddock K, Moutray KL, Poston C, Botvinick EH, Fish MB, Follansbee WP, Hayes S, Iskandrian AE, Mahmarian JJ, Vandecker W. Clinical value of attenuation correction in stress-only Tc-99m sestamibi SPECT imaging. J Nucl Cardiol. 2004 May-Jun; 11(3):273-81.
Pham KH, Botvinick EH. Increased right ventricular activity: artifact of camera head misalignment. J Nucl Cardiol. 2003 Sep-Oct; 10(5):575-6.
Botvinick EH. Scintigraphic blood pool and phase image analysis: the optimal tool for the evaluation of resynchronization therapy. J Nucl Cardiol. 2003 Jul-Aug; 10(4):424-8.
Yun JH, Block M, Botvinick EH. Unique contraction pattern in patients after coronary bypass graft surgery by gated SPECT myocardial perfusion imaging. Clin Nucl Med. 2003 Jan; 28(1):18-24.
Allman KC, Godoy I, Olea E, Lekakis J, Zafir N, Metcalfe M, Prigent F, Botvinick EH, Hendrix GH. Current practice. The role of noninvasive testing and affect of VANQWISH/FRISC II trials on managing acute coronary syndrome patients. J Nucl Cardiol. 2001 Sep-Oct; 8(5):634-6.
Brown JK, Tang HR, Hattner RS, Bocher M, Ratzlaff NW, Kadkade PP, Hasegawa BH, Botvinick EH. Intrinsic dual-energy processing of myocardial perfusion images. J Nucl Med. 2000 Jul; 41(7):1287-97.
Redberg RF, Nishino M, McElhinney DB, Dae MW, Botvinick EH. Long-term estrogen replacement therapy is associated with improved exercise capacity in postmenopausal women without known coronary artery disease. Am Heart J. 2000 Apr; 139(4):739-44.
Kerwin WF, Botvinick EH, O'Connell JW, Merrick SH, DeMarco T, Chatterjee K, Scheibly K, Saxon LA. Ventricular contraction abnormalities in dilated cardiomyopathy: effect of biventricular pacing to correct interventricular dyssynchrony. J Am Coll Cardiol. 2000 Apr; 35(5):1221-7.
Challa S, Botvinick EH, Neymark E, Price D, Hawkins RA. An unusual presentation of non-Hodgkin's lymphoma: a case report. Clin Nucl Med. 2000 Feb; 25(2):150-1.
Oka RK, De Marco T, Haskell WL, Botvinick E, Dae MW, Bolen K, Chatterjee K. Impact of a home-based walking and resistance training program on quality of life in patients with heart failure. Am J Cardiol. 2000 Feb 01; 85(3):365-9.
Barron HV, Sciammarella MG, Lenihan K, Michaels AD, Botvinick EH. Effects of the repeated administration of adenosine and heparin on myocardial perfusion in patients with chronic stable angina pectoris. Am J Cardiol. 2000 Jan 01; 85(1):1-7.
Bobba K, Botvinick EH, Sciammarella MG, Starsken NF, Zhu YY, Lapidus A, Dae MW. Is there any advantage to the acquisition of 24-hour thallium images, in the presence of persistent perfusion defects at 4 h after reinjection? Eur J Nucl Med. 1998 May; 25(5):509-14.
Botvinick EH, O'Connell JW, Kadkade PP, Glickman SL, Dae MW, Cohen TJ, Abbott J, Krishnan R. Potential added value of three-dimensional reconstruction and display of single photon emission computed tomographic gated blood pool images. J Nucl Cardiol. 1998 May-Jun; 5(3):245-55.
DePuey EG, Port S, Wackers FJ, Rozanski A, Botvinick EH, Dae MW, Tamaki N. Nonperfusion applications in nuclear cardiology: report of a task force of the American Society of Nuclear Cardiology. J Nucl Cardiol. 1998 Mar-Apr; 5(2):218-31.
Segall GM, Stepp C, Kadkade PP, Dae MW, Botvinick EH. Fast acquisition of myocardial SPECT images with Tc-99m sestamibi for the diagnosis of coronary artery disease. J Nucl Cardiol. 1997 Sep-Oct; 4(5):358-63.
Huesman RH, Klein GJ, Reutter BW, Coxson PG, Botvinick EH, Budinger TF. Strategies for extraction of quantitative data from volumetric dynamic cardiac positron emission tomography data. Cardiology. 1997 Jan-Feb; 88(1):54-61.
Chou TM, Sudhir K, Amidon TM, Klinski CS, DeMarco T, Chatterjee K, Botvinick EH. Comparison of adenosine to dipyridamole in degree of coronary hyperemic response in heart transplant recipients. Am J Cardiol. 1996 Oct 15; 78(8):908-13.
Hendel RC, Verani MS, Miller DD, Wackers FJ, McMahon M, Cerqueira MD, Botvinick EH, Kvols L, Gerson MC. Diagnostic utility of tomographic myocardial perfusion imaging with technetium 99m furifosmin (Q12) compared with thallium 201: results of a phase III multicenter trial. J Nucl Cardiol. 1996 Jul-Aug; 3(4):291-300.
Knollmann FD, Mäurer J, Kücherer H, Böck JC, O'Connell JW, Botvinick E, Eichstädt HW, Felix R. Cardiac activation mapping by MRI. MAGMA. 1996 Mar; 4(1):19-25.
Botvinick EH. Stress imaging. Current clinical options for the diagnosis, localization, and evaluation of coronary artery disease. Med Clin North Am. 1995 Sep; 79(5):1025-61.
Dae MW, O'Connell JW, Botvinick EH, Chin MC. Acute and chronic effects of transient myocardial ischemia on sympathetic nerve activity, density, and norepinephrine content. Cardiovasc Res. 1995 Aug; 30(2):270-80.
Redberg RF, Sobol Y, Chou TM, Malloy M, Kumar S, Botvinick E, Kane J. Adenosine-induced coronary vasodilation during transesophageal Doppler echocardiography. Rapid and safe measurement of coronary flow reserve ratio can predict significant left anterior descending coronary stenosis. Circulation. 1995 Jul 15; 92(2):190-6.
Segall GM, Atwood JE, Botvinick EH, Dae MW, Lucas JR. Variability of normal coronary anatomy: implications for the interpretation of thallium-SPECT myocardial perfusion images in single-vessel disease. J Nucl Med. 1995 Jun; 36(6):944-51.
Foster E, O'Kelly B, LaPidus A, Sandler D, Tucker K, Dae M, Schiller NB, Botvinick EH. Segmental analysis of resting echocardiographic function and stress scintigraphic perfusion: implications for myocardial viability. Am Heart J. 1995 Jan; 129(1):7-14.
Botvinick EH. A consideration of current clinical options for stress imaging in the diagnosis and evaluation of coronary artery disease. J Nucl Cardiol. 1994 Sep-Oct; 1(5 Pt 2):S147-70.
Lee MA, Dae MW, Langberg JJ, Griffin JC, Chin MC, Finkbeiner WE, O'Connell JW, Botvinick E, Scheinman MM, Rosenqvist M. Effects of long-term right ventricular apical pacing on left ventricular perfusion, innervation, function and histology. J Am Coll Cardiol. 1994 Jul; 24(1):225-32.
Krishnan R, Lu J, Dae MW, Botvinick EH. Does myocardial perfusion scintigraphy demonstrate clinical usefulness in patients with markedly positive exercise tests? An assessment of the method in a high-risk subset. Am Heart J. 1994 Apr; 127(4 Pt 1):804-16.
Wolfe CL, O'Connell JW, Sievers RE, Cobb C, Dae MW, Botvinick E. Assessment of perfused left ventricular mass in normal, ischemic, and reperfused myocardium by means of single-photon emission computed tomography of technetium-99m isonitrile. Am Heart J. 1993 Dec; 126(6):1275-86.
Newman D, Munoz L, Chin M, Franz M, Herre J, Scheinman MM, Botvinick E, Dae M. Effects of canine myocardial infarction on sympathetic efferent neuronal function: scintigraphic and electrophysiologic correlates. Am Heart J. 1993 Nov; 126(5):1106-12.
Botvinick EH, Dae MW, Krishnan R, Ewing S. Hypertrophic cardiomyopathy in the young: another form of ischemic cardiomyopathy? J Am Coll Cardiol. 1993 Sep; 22(3):805-7.
Krishnan R, Lu J, Zhu YY, Dae MW, Botvinick EH. Myocardial perfusion scintigraphy in left bundle branch block: a perspective on the issue from image analysis in a clinical context. Am Heart J. 1993 Sep; 126(3 Pt 1):578-86.
Lucas JR, Botvinick EH, Dae MW. Myocardial viability: evidence provided by the analysis of left ventricular systolic function. Coron Artery Dis. 1993 Jun; 4(6):485-94.
Botvinick EH. The proper tool for the job. J Am Coll Cardiol. 1993 May; 21(6):1328-31.
Starksen NF, O'Connell W, Dae MW, Botvinick EH. Basal interventricular septal thallium-201 defects: real or artifact? Clin Nucl Med. 1993 Apr; 18(4):291-7.
Botvinick EH, Zhu YY, O'Connell WJ, Dae MW. A quantitative assessment of patient motion and its effect on myocardial perfusion SPECT images. J Nucl Med. 1993 Feb; 34(2):303-10.
Munoz del Romeral L, Dae MW, Ports TA, Botvinick EH. Diagnostic and prognostic value of ambulatory electrocardiographic monitoring. Am Heart J. 1992 Nov; 124(5):1213-9.
Dae MW, De Marco T, Botvinick EH, O'Connell JW, Hattner RS, Huberty JP, Yuen-Green MS. Scintigraphic assessment of MIBG uptake in globally denervated human and canine hearts--implications for clinical studies. J Nucl Med. 1992 Aug; 33(8):1444-50.
Cohen TJ, Tucker KJ, Abbott JA, Botvinick EH, Foster E, Schiller NB, O'Connell JW, Scheinman MM. Usefulness of adenosine in augmenting ventricular preexcitation for noninvasive localization of accessory pathways. Am J Cardiol. 1992 May 01; 69(14):1178-85.
Tucker KJ, Cohen TJ, Botvinick EH, Schiller NB. The applications of adenosine in noninvasive cardiac imaging. Herz. 1992 Apr; 17(2):122-36.
Botvinick EH. Advances in myocardial scintigraphy in coronary heart disease. Am J Card Imaging. 1992 Mar; 6(1):1-2.
Kuecherer HF, Abbott JA, Botvinick EH, Scheinman ED, O'Connell JW, Scheinman MM, Foster E, Schiller NB. Two-dimensional echocardiographic phase analysis. Its potential for noninvasive localization of accessory pathways in patients with Wolff-Parkinson-White syndrome. Circulation. 1992 Jan; 85(1):130-42.
Watters TA, Botvinick EH, Dae MW, Cahalan M, Urbanowicz J, Benefiel DJ, Schiller NB, Goldstone G, Reilly L, Stoney RJ. Comparison of the findings on preoperative dipyridamole perfusion scintigraphy and intraoperative transesophageal echocardiography: implications regarding the identification of myocardium at ischemic risk. J Am Coll Cardiol. 1991 Jul; 18(1):93-100.
Botvinick EH, Dae MW. Dipyridamole perfusion scintigraphy. Semin Nucl Med. 1991 Jul; 21(3):242-65.
Oeff M, Scheinman MM, Abbott JA, Botvinick EH, Griffin JC, Herre JM, Dae MW. Phase image triangulation of accessory pathways in patients undergoing catheter ablation of posteroseptal pathways. Pacing Clin Electrophysiol. 1991 Jun; 14(6):1072-85.
Dae MW, Herre JM, O'Connell JW, Botvinick EH, Newman D, Munoz L. Scintigraphic assessment of sympathetic innervation after transmural versus nontransmural myocardial infarction. J Am Coll Cardiol. 1991 May; 17(6):1416-23.
Rosenqvist M, Isaaz K, Botvinick EH, Dae MW, Cockrell J, Abbott JA, Schiller NB, Griffin JC. Relative importance of activation sequence compared to atrioventricular synchrony in left ventricular function. Am J Cardiol. 1991 Jan 15; 67(2):148-56.
Zhu YY, Chung WS, Botvinick EH, Dae MW, Lim AD, Ports TA, Danforth JW, Wolfe CL, Goldschlager N, Chatterjee K. Dipyridamole perfusion scintigraphy: the experience with its application in one hundred seventy patients with known or suspected unstable angina. Am Heart J. 1991 Jan; 121(1 Pt 1):33-43.
Botvinick EH. The promise of technetium-99m-based perfusion imaging agents. Circulation. 1990 Dec; 82(6):2277-80.
Landzberg JS, Franklin JO, Mahawar SK, Himelman RB, Botvinick EH, Schiller NB, Springer MJ, Griffin JC. Benefits of physiologic atrioventricular synchronization for pacing with an exercise rate response. Am J Cardiol. 1990 Jul 15; 66(2):193-7.
Dae MW, Botvinick EH. Imaging of the heart using metaiodobenzylguanidine. J Thorac Imaging. 1990 Jul; 5(3):31-6.
Urbanowicz JH, Shaaban MJ, Cohen NH, Cahalan MK, Botvinick EH, Chatterjee K, Schiller NB, Dae MW, Matthay MA. Comparison of transesophageal echocardiographic and scintigraphic estimates of left ventricular end-diastolic volume index and ejection fraction in patients following coronary artery bypass grafting. Anesthesiology. 1990 Apr; 72(4):607-12.
Botvinick EH. "Hot spot" imaging agents for acute myocardial infarction. J Nucl Med. 1990 Feb; 31(2):143-6.
Gober JR, Schaefer S, Camacho SA, DeGroot M, Obregon R, Botvinick EH, Weiner M, Massie B. Epicardial and endocardial localized 31P magnetic resonance spectroscopy: evidence for metabolic heterogeneity during regional ischemia. Magn Reson Med. 1990 Feb; 13(2):204-15.
Botvinick EH. Late reversibility: a viability issue. J Am Coll Cardiol. 1990 Feb; 15(2):341-4.
Hylton NM, Chung WS, Botvinick EH, Schiller NB, Sheldon P, Kaufman L. Oblique reformatting of multislice magnetic resonance images for improved visualization of coronary arteries. J Digit Imaging. 1990 Feb; 3(1):34-7.
Botvinick EH, Dae MW, O'Connell JW. Blood pool scintigraphy. Cardiol Clin. 1989 Aug; 7(3):537-63.
Bouchard A, Sanz N, Botvinick EH, Phillips N, Heilbron D, Byrd BF, Karam JH, Schiller NB. Noninvasive assessment of cardiomyopathy in normotensive diabetic patients between 20 and 50 years old. Am J Med. 1989 Aug; 87(2):160-6.
Schaefer S, Camacho SA, Gober J, Obregon RG, DeGroot MA, Botvinick EH, Massie B, Weiner MW. Response of myocardial metabolites to graded regional ischemia: 31P NMR spectroscopy of porcine myocardium in vivo. Circ Res. 1989 May; 64(5):968-76.
Bouchard A, Yock P, Schiller NB, Blumlein S, Botvinick EH, Greenberg B, Cheitlin M, Massie BM. Value of color Doppler estimation of regurgitant volume in patients with chronic aortic insufficiency. Am Heart J. 1989 May; 117(5):1099-105.
Dae M, Wen YM, Botvinick EH, Scheinman M. ECG left anterior fascicular block reveals diverse patterns on scintigraphic phase analysis. Am Heart J. 1989 Apr; 117(4):861-9.
Schechtmann N, Botvinick EH, Dae M, Scheinman MM, O'Connell JW, Davis J, Winston S, Schwartz A, Abbott J. The scintigraphic characteristics of ventricular pre-excitation through Mahaim fibers with the use of phase analysis. J Am Coll Cardiol. 1989 Mar 15; 13(4):882-91.
Dae MW, O'Connell JW, Botvinick EH, Ahearn T, Yee E, Huberty JP, Mori H, Chin MC, Hattner RS, Herre JM. Scintigraphic assessment of regional cardiac adrenergic innervation. Circulation. 1989 Mar; 79(3):634-44.
Schaefer S, Gober J, Valenza M, Karczmar GS, Matson GB, Camacho SA, Botvinick EH, Massie B, Weiner MW. Nuclear magnetic resonance imaging-guided phosphorus-31 spectroscopy of the human heart. J Am Coll Cardiol. 1988 Dec; 12(6):1449-55.
Zhu YY, Lee W, Botvinick E, Dae M, Chatterjee K, Danforth J, Ports T. The clinical and pathophysiologic implications of pain, ST abnormalities, and scintigraphic changes induced during dipyridamole infusion: their relationships to the peripheral hemodynamic response. Am Heart J. 1988 Oct; 116(4):1071-80.
Botvinick EH. Breast attenuation artifacts in Tl-201 scintigraphy. Radiology. 1988 Sep; 168(3):878-9.
Camacho SA, Lanzer P, Toy BJ, Gober J, Valenza M, Botvinick EH, Weiner MW. In vivo alterations of high-energy phosphates and intracellular pH during reversible ischemia in pigs: a 31P magnetic resonance spectroscopy study. Am Heart J. 1988 Sep; 116(3):701-8.
Zhu YY, Botvinick E, Dae M, Golden J, Hattner R, Scheinman M. Gallium lung scintigraphy in amiodarone pulmonary toxicity. Chest. 1988 Jun; 93(6):1126-31.
Botvinick EH, Dae M. Dipyridamole myocardial perfusion scintigraphy. West J Med. 1988 Apr; 148(4):454-5.
White RD, Holt WW, Cheitlin MD, Cassidy MM, Ports TA, Lim AD, Botvinick EH, Higgins CB. Estimation of the functional and anatomic extent of myocardial infarction using magnetic resonance imaging. Am Heart J. 1988 Apr; 115(4):740-8.
Botvinick EH, O'Connell WJ, Dae MW, Hattner RS, Schechtmann NM. Analysis of thallium-201 "washout" from parametric color coded images. J Nucl Med. 1988 Mar; 29(3):302-10.
Camacho SA, Wikman-Coffelt J, Wu ST, Watters TA, Botvinick EH, Sievers R, James TL, Jasmin G, Parmley WW. Improvement in myocardial performance without a decrease in high-energy phosphate metabolites after isoproterenol in Syrian cardiomyopathic hamsters. Circulation. 1988 Mar; 77(3):712-9.
Camacho SA, Parmley WW, James TL, Abe H, Wu ST, Botvinick EH, Watters TA, Schiller N, Sievers R, Wikman-Coffelt J. Substrate regulation of the nucleotide pool during regional ischaemia and reperfusion in an isolated rat heart preparation: a phosphorus-31 magnetic resonance spectroscopy analysis. Cardiovasc Res. 1988 Mar; 22(3):193-203.
Watters TA, Botvinick E, Parmley WW, Wu S, Wikman-Coffelt J. Chemomechanics of altered perfusion pressure in rat hearts. Basic Res Cardiol. 1988 Jan-Feb; 83(1):32-42.
Garrett JS, Jaschke W, Aherne T, Botvinick EH, Higgins CB, Lipton MJ. Quantitation of intracardiac shunts by cine-CT. J Comput Assist Tomogr. 1988 Jan-Feb; 12(1):82-7.
White RD, Cassidy MM, Cheitlin MD, Emilson B, Ports TA, Lim AD, Botvinick EH, Schiller NB, Higgins CB. Segmental evaluation of left ventricular wall motion after myocardial infarction: magnetic resonance imaging versus echocardiography. Am Heart J. 1988 Jan; 115(1 Pt 1):166-75.
Watters TA, Wendland MF, Parmley WW, James TL, Botvinick EH, Wu ST, Sievers R, Wikman-Coffelt J. Factors influencing myocardial response to metabolic acidosis in isolated rat hearts. Am J Physiol. 1987 Nov; 253(5 Pt 2):H1261-70.
Botvinick E, Schechtmann N, Dae M, Scheinman M, Davis J, Herre J, Iskikian T, Abbott J. Augmented preexcitation assessed by scintigraphic phase analysis during atrial pacing. Am Heart J. 1987 Oct; 114(4 Pt 1):738-45.
Bouchard A, Watters TA, Wu S, Parmley WW, Stone RD, Botvinick E, Sievers R, Jasmin G, Wikman-Coffelt J. Effects of altered coronary perfusion pressure on function and metabolism of normal and cardiomyopathic hamster hearts. J Mol Cell Cardiol. 1987 Oct; 19(10):1011-23.
Axelrod RJ, De Marco T, Dae M, Botvinick EH, Chatterjee K. Hemodynamic and clinical evaluation of piroximone, a new inotrope-vasodilator agent, in severe congestive heart failure. J Am Coll Cardiol. 1987 May; 9(5):1124-30.
Cahalan MK, Litt L, Botvinick EH, Schiller NB. Advances in noninvasive cardiovascular imaging: implications for the anesthesiologist. Anesthesiology. 1987 Mar; 66(3):356-72.
Mickelson JK, Byrd BF, Bouchard A, Botvinick EH, Schiller NB. Left ventricular dimensions and mechanics in distance runners. Am Heart J. 1986 Dec; 112(6):1251-6.
Lanzer P, Garrett J, Lipton MJ, Gould R, Sievers R, O'Connell W, Botvinick E, Higgins CB. Quantitation of regional myocardial function by cine computed tomography: pharmacologic changes in wall thickness. J Am Coll Cardiol. 1986 Sep; 8(3):682-92.
Blumlein S, Bouchard A, Schiller NB, Dae M, Byrd BF, Ports T, Botvinick EH. Quantitation of mitral regurgitation by Doppler echocardiography. Circulation. 1986 Aug; 74(2):306-14.
Garrett JS, Schiller NB, Botvinick EH, Higgins CB, Lipton MJ. Cine-computed tomography of Ebstein anomaly. J Comput Assist Tomogr. 1986 Jul-Aug; 10(4):664-6.
Hansen RM, Viquerat CE, Matthay MA, Wiener-Kronish JP, DeMarco T, Bahtia S, Marks JD, Botvinick EH, Chatterjee K. Poor correlation between pulmonary arterial wedge pressure and left ventricular end-diastolic volume after coronary artery bypass graft surgery. Anesthesiology. 1986 Jun; 64(6):764-70.
McNamara MT, Tscholakoff D, Revel D, Soulen R, Schechtmann N, Botvinick E, Higgins CB. Differentiation of reversible and irreversible myocardial injury by MR imaging with and without gadolinium-DTPA. Radiology. 1986 Mar; 158(3):765-9.
Schiller NB, Botvinick EH. Noninvasive quantitation of the left heart by echocardiography and scintigraphy. Cardiovasc Clin. 1986; 17(1):45-93.
Lanzer P, Dean PB, Lipton MJ, Sievers R, Botvinick E, Higgins CB. Effects of intravenous administration of a new nonionic dimeric contrast medium on the coronary circulation. Comparison with monomeric ionic and nonionic media. Invest Radiol. 1985 Oct; 20(7):746-50.
Garrett JS, Lanzer P, Jaschke W, Botvinick E, Sievers R, Higgins CB, Lipton MJ. Measurement of cardiac output by cine computed tomography. Am J Cardiol. 1985 Oct 01; 56(10):657-61.
Canhasi B, Dae M, Botvinick E, Lanzer P, Schechtmann N, Faulkner D, O'Connell W, Schiller N. Interaction of "supplementary" scintigraphic indicators of ischemia and stress electrocardiography in the diagnosis of multivessel coronary disease. J Am Coll Cardiol. 1985 Sep; 6(3):581-8.
Wahr DW, Ports TA, Botvinick EH, Dae M, Schechtmann N, Huberty J, Hattner RS, O'Connell JW, Turley K. The effects of coronary angioplasty and reperfusion on distribution of myocardial flow. Circulation. 1985 Aug; 72(2):334-43.
Viquerat CE, Hansen RM, Botvinick EH, Dae MW, Wiener-Kronish JP, Matthay MA. Undrained bloody pericardial effusion in the early postoperative period after coronary bypass surgery: a prospective blood pool study. Am Heart J. 1985 Aug; 110(2):335-41.
Lanzer PA, Botvinick EH, Higgins CB. [Imaging of the heart using nuclear magnetic resonance tomography. I: Tomography]. Z Kardiol. 1985 Aug; 74(8):423-34.
Dae M, Canhasi B, Botvinick E, Olvera S, Schechtmann N, Engelstad B, Hattner R, Schiller N, O'Connell W, Faulkner D. The etiology and implications of dense cavitary "photopenia" on myocardial perfusion scintigraphy. Invest Radiol. 1985 Jul; 20(4):388-92.
Lanzer P, Barta C, Botvinick EH, Wiesendanger HU, Modin G, Higgins CB. ECG-synchronized cardiac MR imaging: method and evaluation. Radiology. 1985 Jun; 155(3):681-6.
Higgins CB, Byrd BF, McNamara MT, Lanzer P, Lipton MJ, Botvinick E, Schiller NB, Crooks LE, Kaufman L. Magnetic resonance imaging of the heart: a review of the experience in 172 subjects. Radiology. 1985 Jun; 155(3):671-9.
Byrd BF, Schiller NB, Botvinick EH, Higgins CB. Normal cardiac dimensions by magnetic resonance imaging. Am J Cardiol. 1985 May 01; 55(11):1440-2.
Higgins CB, Byrd BF, Stark D, McNamara M, Lanzer P, Lipton MJ, Schiller NB, Botvinick E, Chatterjee K. Magnetic resonance imaging in hypertrophic cardiomyopathy. Am J Cardiol. 1985 Apr 15; 55(9):1121-6.
McNamara MT, Higgins CB, Schechtmann N, Botvinick E, Lipton MJ, Chatterjee K, Amparo EG. Detection and characterization of acute myocardial infarction in man with use of gated magnetic resonance. Circulation. 1985 Apr; 71(4):717-24.
Wen YM, Botvinick EH. [Diagnosis of left bundle branch block with the phase analysis of radionuclide images]. Zhonghua Xin Xue Guan Bing Za Zhi. 1985 Mar; 13(1):24-8.
Wen YM, Botvinick EH, Sheinman MM. Assessment of left intraventricular block by scintigraphic analysis. Chin Med J (Engl). 1985 Feb; 98(2):135-42.
Higgins CB, Lanzer P, Stark D, Botvinick E, Schiller NB, Lipton MJ, Crooks LE, Kaufman L. Assessment of cardiac anatomy using nuclear magnetic resonance imaging. J Am Coll Cardiol. 1985 Jan; 5(1 Suppl):77S-81S.
Lallemand D, Wesbey GE, Gooding CA, Ehman R, Brasch RC, Ortendahl D, McNamara MT, Lanzer P, Botvinick E, Crooks E. Cardiosynchronous MRI intensity changes of the great vessels and pulmonary circulation. A preliminary report. Ann Radiol (Paris). 1985; 28(3-4):299-307.
Lallemand D, Gooding CA, Wesbey GE, Brasch RC, Botvinick E, Lanzer P, McNamara MT. Magnetic resonance (MR) imaging of aorta and pulmonary circulation. Initial experience with ECG-gating. Ann Radiol (Paris). 1985; 28(3-4):289-98.
Crooks LE, Barker B, Chang H, Feinberg D, Hoenninger JC, Watts JC, Arakawa M, Kaufman L, Sheldon PE, Botvinick E. Magnetic resonance imaging strategies for heart studies. Radiology. 1984 Nov; 153(2):459-65.
Kereiakes DJ, Viquerat C, Lanzer P, Botvinick EH, Spangenberg R, Buckingham M, Parmley WW, Chatterjee K. Mechanisms of improved left ventricular function following intravenous MDL 17,043 in patients with severe chronic heart failure. Am Heart J. 1984 Nov; 108(5):1278-84.
Frais M, Botvinick E, Shosa D, O'Connell W, Pacheco Alvarez J, Dae M, Hattner R, Faulkner D. Phase image characterization of localized and generalized left ventricular contraction abnormalities. J Am Coll Cardiol. 1984 Nov; 4(5):987-98.
Botvinick EH. The scintigraphic identification of "severe myocardial ischemia". G Ital Cardiol. 1984 Nov; 14(11):911-6.
DiCarlo LA, Botvinick EH, Canhasi BS, Schwartz AS, Chatterjee K. Value of noninvasive assessment of patients with atypical chest pain and suspected coronary spasm using ergonovine infusion and thallium-201 scintigraphy. Am J Cardiol. 1984 Oct 01; 54(7):744-8.
Bhandari A, Morady F, Shen EN, Schwartz AB, Botvinick E, Scheinman MM. Catheter-induced His bundle ablation in a patient with reentrant tachycardia associated with a nodoventricular tract. J Am Coll Cardiol. 1984 Sep; 4(3):611-6.
Kereiakes DJ, Ports TA, Botvinick EH, Schiller NB, Turley K, Chatterjee K. Right ventricular myocardial infarction with ventricular septal rupture. Am Heart J. 1984 Jun; 107(6):1257-9.
Brundage BH, Massie BM, Botvinick EH. Improved regional ventricular function after successful surgical revascularization. J Am Coll Cardiol. 1984 Apr; 3(4):902-8.
Higgins CB, Lanzer P, Stark D, Botvinick E, Schiller NB, Crooks L, Kaufman L, Lipton MJ. Imaging by nuclear magnetic resonance in patients with chronic ischemic heart disease. Circulation. 1984 Mar; 69(3):523-31.
Botvinick E, Frais M, O'Connell W, Faulkner D, Scheinman M, Morady F, Sung R, Shosa D, Dae M. Phase image evaluation of patients with ventricular pre-excitation syndromes. J Am Coll Cardiol. 1984 Mar; 3(3):799-814.
Dae MW, Botvinick EH. Characterization of conduction and concentration abnormalities by scintigraphic phase analysis. Int J Cardiol. 1984 Feb; 5(2):244-53.
Lanzer P, Botvinick EH, Schiller NB, Crooks LE, Arakawa M, Kaufman L, Davis PL, Herfkens R, Lipton MJ, Higgins CB. Cardiac imaging using gated magnetic resonance. Radiology. 1984 Jan; 150(1):121-7.
Wesbey G, Higgins CB, Lanzer P, Botvinick E, Lipton MJ. Imaging and characterization of acute myocardial infarction in vivo by gated nuclear magnetic resonance. Circulation. 1984 Jan; 69(1):125-30.
Misbach GA, Botvinick EH, Tyberg JV, Parmley WW, Dunn RF, Frais M. The functional implications of scintigraphic measures of myocardial ischemia and infarction. Am Heart J. 1983 Nov; 106(5 Pt 1):996-1002.
Hlatky MA, Lee KL, Botvinick EH, Brundage BH. Diagnostic test use in different practice settings. A controlled comparison. Arch Intern Med. 1983 Oct; 143(10):1886-9.
Engelstad BL, Wagner S, Herfkens R, Botvinick E, Brundage B, Lipton M. Evaluation of the post-coronary artery bypass patient by myocardial perfusion scintigraphy and computed tomography. AJR Am J Roentgenol. 1983 Sep; 141(3):507-12.
Higgins CB, Botvinick EH, Lanzer P, Herfkens R, Lipton MJ, Crooks LE, Kaufman L. Cardiovascular imaging with nuclear magnetic resonance. Cardiol Clin. 1983 Aug; 1(3):527-39.
Goldstein JA, Vlahakes GJ, Verrier ED, Schiller NB, Botvinick E, Tyberg JV, Parmley WW, Chatterjee K. Volume loading improves low cardiac output in experimental right ventricular infarction. J Am Coll Cardiol. 1983 Aug; 2(2):270-8.
Herfkens RJ, Higgins CB, Hricak H, Lipton MJ, Crooks LE, Lanzer P, Botvinick E, Brundage B, Sheldon PE, Kaufman L. Nuclear magnetic resonance imaging of the cardiovascular system: normal and pathologic findings. Radiology. 1983 Jun; 147(3):749-59.
Botvinick EH, Perez-Gonzalez JF, Dunn R, Ports T, Chatterjee K, Parmley W. Late prognostic value of scintigraphic parameters of acute myocardial infarction size in complicated myocardial infarction without heart failure. Am J Cardiol. 1983 Apr; 51(7):1045-51.
Schwartz AB, Donmichael TA, Botvinick EH, Ishimori T, Parmley WW, Chatterjee K. Variability in coronary hemodynamics in response to ergonovine in patients with normal coronary arteries and atypical chest pain. J Am Coll Cardiol. 1983 Mar; 1(3):797-803.
Sung RJ, Shen EN, Morady F, Scheinman MM, Hess D, Botvinick EH. Electrophysiologic mechanism of exercise-induced sustained ventricular tachycardia. Am J Cardiol. 1983 Feb; 51(3):525-30.
Botvinick EH, Glazer HB, Shosa DW. What is the reliability and the utility of scintigraphic methods for the assessment of ventricular function? Cardiovasc Clin. 1983; 13(1):65-90.
Hlatky M, Botvinick E, Brundage B. The independent value of exercise thallium scintigraphy to physicians. Circulation. 1982 Nov; 66(5):953-9.
Perez-Gonzalez J, Botvinick EH, Dunn R, Rahimtoola S, Ports T, Chatterjee K, Parmley WW. The late prognostic value of acute scintigraphic measurement of myocardial infarction size. Circulation. 1982 Nov; 66(5):960-71.
Botvinick EH, Frais MA, Shosa DW, O'Connell JW, Pacheco-Alvarez JA, Scheinman M, Hattner RS, Morady F, Faulkner DB. An accurate means of detecting and characterizing abnormal patterns of ventricular activation by phase image analysis. Am J Cardiol. 1982 Aug; 50(2):289-98.
Frais MA, Botvinick EH, Shosa DW, O'Connell WJ, Scheinman MM, Hattner RS, Morady F. Phase image characterization of ventricular contraction in left and right bundle branch block. Am J Cardiol. 1982 Jul; 50(1):95-105.
Hlatky M, Botvinick E, Brundage B. Diagnostic accuracy of cardiologists compared with probability calculations using Bayes' rule. Am J Cardiol. 1982 Jun; 49(8):1927-31.
Topol EJ, Goldschlager N, Ports TA, Dicarlo LA, Schiller NB, Botvinick EH, Chatterjee K. Hemodynamic benefit of atrial pacing in right ventricular myocardial infarction. Ann Intern Med. 1982 May; 96(5):594-7.
Dunn RF, Botvinick EH, Benge W, Chatterjee K, Parmley WW. The significance of nitroglycerin-induced changes in ventricular function after acute myocardial infarction. Am J Cardiol. 1982 May; 49(7):1719-27.
Frais M, Botvinick E, Shosa D, O'Connell W. Are regions of ischaemia detected on stress perfusion scintigraphy predictive of sites of subsequent myocardial infarction? Br Heart J. 1982 Apr; 47(4):357-64.
Botvinick E, Dunn R, Frais M, O'Connell W, Shosa D, Herfkens R, Scheinman M. The phase image: its relationship to patterns of contraction and conduction. Circulation. 1982 Mar; 65(3):551-60.
Seder JS, Botvinick EH, Rahimtoola SH, Goldstone J, Price DC. Detecting and localizing peripheral arterial disease: assessment of 201Tl scintigraphy. AJR Am J Roentgenol. 1981 Aug; 137(2):373-80.
Dunn RF, Wolff L, Wagner S, Botvinick EH. The inconsistent pattern of thallium defects: a clue to the false positive perfusion scintigram. Am J Cardiol. 1981 Aug; 48(2):224-32.
Massie B, Botvinick E, Arnold S, Shames D, Brundage B, Hanlon JT, Sheldon K. Contrast enhancement of thallium-201 myocardial scintigrams: improved sensitivity with diminished specificity in coronary disease detection. Am Heart J. 1981 Jul; 102(1):37-44.
Botvinick EH, Schiller NB. The complementary roles of M-mode echocardiography and scintigraphy in the evaluation of adults with suspected left-to-right shunts. Additional observations on the role of two-dimensional echocardiography. Circulation. 1980 Nov; 62(5):1070-9.
Greenberg BH, Drew D, Botvinick EH, Werner JA, Klausner SC, Shames DM, Parmley WW. Evaluation of left ventricular performance by gated radionuclide angiography. Clin Nucl Med. 1980 Jun; 5(6):245-54.
Botvinick EH, Dunn RF, Hattner RS, Massie BM. A consideration of factors affecting the diagnostic accuracy of thallium-201 myocarial perfusion scintigraphy in detecting coronary artery disease. Semin Nucl Med. 1980 Apr; 10(2):157-67.
Botvinick EH. Myocardial perfusion scintigraphy. Arch Intern Med. 1980 Feb; 140(2):169-71.
Massie BM, Botvinick EH, Brundage BH. Correlation of thallium-201 scintigrams with coronary anatomy: factors affecting region by region sensitivity. Am J Cardiol. 1979 Oct; 44(4):616-22.
Schiller NB, Acquatella H, Ports TA, Drew D, Goerke J, Ringertz H, Silverman NH, Brundage B, Botvinick EH, Boswell R, Carlsson E, Parmley WW. Left ventricular volume from paired biplane two-dimensional echocardiography. Circulation. 1979 Sep; 60(3):547-55.
Dash H, Massie BM, Botvinick EH, Brundage BH. The noninvasive identification of left main and three-vessel coronary artery disease by myocardial stress perfusion scintigraphy and treadmill exercise electrocardiography. Circulation. 1979 Aug; 60(2):276-84.
Massie BM, Botvinick EH, Werner JA, Chatterjee K, Parmley WW. Myocardial scintigraphy with technetium-99m stannous pyrophosphate: an insensitive test for nontransmural myocardial infarction. Am J Cardiol. 1979 Feb; 43(2):186-92.
Massie BM, Botvinick EH, Brundage BH, Greenberg B, Shames D, Gelberg H. Relationship of regional myocardial perfusion to segmental wall motion: a physiologic basis for understanding the presence and reversibility of asynergy. Circulation. 1978 Dec; 58(6):1154-63.
Schor RA, Massie BM, Botvinick EH, Shames DM. Gallium-67 uptake in silent myocardial infarction: a case report. Radiology. 1978 Oct; 129(1):117-8.
Botvinick EH, Shames DM, Sharpe DN, Klausner SC, Werner JA, Chatterjee K, Parmley WW. The specificity of pyrophosphate myocardial scintigrams in patients with prior myocardial infarction: concise communication. J Nucl Med. 1978 Oct; 19(10):1121-5.
Greenberg BH, Massie BM, Brundage BH, Botvinick EH, Parmley WW, Chatterjee K. Beneficial effects of hydralazine in severe mitral regurgitation. Circulation. 1978 Aug; 58(2):273-9.
Greenberg BH, Hart R, Botvinick EH, Werner JA, Brundage BH, Shames DM, Chatterjee K, Parmley WW. Thallium-201 myocardial perfusion scintigraphy to evaluate patients after coronary bypass surgery. Am J Cardiol. 1978 Aug; 42(2):167-76.
Sharpe DN, Botvinick EH, Shames DM, Schiller NB, Massie BM, Chatterjee K, Parmley WW. The noninvasive diagnosis of right ventricular infarction. Circulation. 1978 Mar; 57(3):483-90.
Sharpe DN, Botvinick EH, Shames DM, Norman A, Chatterjee K, Parmley WW. The clinical estimation of acute myocardial infarct size with 99mTechnetium pyrophosphate scintigraphy. Circulation. 1978 Feb; 57(2):307-13.
Massie B, Botvinick EH, Shames D, Taradash M, Werner J, Schiller N. Myocardial perfusion scintigraphy in patients with mitral valve prolapse: Its advantage over stress electrocardiography in diagnosing associated coronary artery disease and its implications for the etiology of chest pain. Circulation. 1978 Jan; 57(1):19-26.
Botvinick EH, Shames D, Parmley WW. Myocardial scintigraphy in coronary artery disease. Cleve Clin Q. 1978; 45(1):13-6.
Botvinick EH, Taradash MR, Shames DM, Parmley WW. Thallium-20 1 myocardial perfusion scintigraphy for the clinical clarification of normal, abnormal and equivocal electrocardiographic stress tests. Am J Cardiol. 1978 Jan; 41(1):43-51.
Schiller NB, Botvinick EH. Right ventricular compression as a sign of cardiac tamponade: an analysis of echocardiographic ventricular dimensions and their clinical implications. Circulation. 1977 Nov; 56(5):774-9.
Klausner SC, Botvinick EH, Shames D, Ullyot DJ, Fishman NH, Roe BB, Ebert PA, Chatterjee K, Parmley WW. The application of radionuclide infarct scintigraphy to diagnose perioperative myocardial infarction following revascularization. Circulation. 1977 Aug; 56(2):173-81.
Botvinick EH, Shames DM, Gershengorn KM, Carlsson E, Ratshin RA, Parmley WW. Myocardial stress perfusion scintigraphy with rubidium-81 versus stress electrocardiography. Am J Cardiol. 1977 Mar; 39(3):364-71.
Tyberg JV, Massie BM, Botvinick EH, Parmley W. The hemodynamics of coronary arterial stenosis. Cardiovasc Clin. 1977; 8(2):71-84.
Prasquier R, Taradash MR, Botvinick EH, Shames DM, Parmley WW. The specificity of the diffuse pattern of cardiac uptake in myocardial infarction imaging with technetium-99m stannous pyrophosphate. Circulation. 1977 Jan; 55(1):61-6.
Botvinick EH, Shames D, Hutchinson JC, Roe BB, Fitzpatrick M. Noninvasive diagnosis of a false left ventricular aneurysm with radioisotope gated cardiac blood pool imaging. Differentiation from true aneurysm. Am J Cardiol. 1976 Jun; 37(7):1089-93.
Lappin HA, Botvinick EH, Parmley WW, Tyberg JV. Myocardial infarction in closed-chest dogs: a simplified method for production. J Appl Physiol. 1975 Nov; 39(5):831-3.
Botvinick EH, Shames D, Lappin H, Tyberg JV, Townsend R, Parmley WW. Noninvasive quantitation of myocardial infarction with technetium 99m pyrophosphate. Circulation. 1975 Nov; 52(5):909-15.
Botvinick EH, Schiller NB, Wickramasekaran R, Klausner SC, Gertz E. Echocardiographic demonstration of early mitral valve closure in severe aortic insufficiency. Its clinical implications. Circulation. 1975 May; 51(5):836-47.