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Xin Mu, MD, MS
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Publications
Xin Mu, MD, MS's Publications
EGFR-mutant transformed small cell lung cancer harbors intratumoral heterogeneity targetable with MEK inhibitor combination therapy.
Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia.
Identification of breast cancer subtypes and drug response prediction through forward and reverse translation.
Photoproximity labeling of c-Myc reveals SLK as a cancer specific co-regulator.
Real-world clinical multi-omics analyses reveal bifurcation of ER-independent and ER-dependent drug resistance to CDK4/6 inhibitors.
Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia.
Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers.
Integrative Analyses of Tumor and Peripheral Biomarkers in the Treatment of Advanced Renal Cell Carcinoma.
Estimate of fetal brain temperature using proton resonance frequency thermometry during 3 Tesla fetal magnetic resonance imaging.
Molecular characterization of renal cell carcinoma tumors from a phase III anti-angiogenic adjuvant therapy trial.
Autism risk gene POGZ promotes chromatin accessibility and expression of clustered synaptic genes.
Avelumab maintenance in advanced urothelial carcinoma: biomarker analysis of the phase 3 JAVELIN Bladder 100 trial.
Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor.
HLA-A*03 and response to immune checkpoint blockade in cancer: an epidemiological biomarker study.
Molecular medicine tumor board: whole-genome sequencing to inform on personalized medicine for a man with advanced prostate cancer.
Avelumab plus axitinib versus sunitinib in advanced renal cell carcinoma: biomarker analysis of the phase 3 JAVELIN Renal 101 trial.
First-in-Human Study of Utomilumab, a 4-1BB/CD137 Agonist, in Combination with Rituximab in Patients with Follicular and Other CD20+ Non-Hodgkin Lymphomas.
Landscape of somatic single nucleotide variants and indels in colorectal cancer and impact on survival.
Standard machine learning approaches outperform deep representation learning on phenotype prediction from transcriptomics data.
Genetic Mechanisms of Immune Evasion in Colorectal Cancer.
Inherited DNA-Repair Defects in Colorectal Cancer.
Multi-omics profiling of younger Asian breast cancers reveals distinctive molecular signatures.
TIME (Tumor Immunity in the MicroEnvironment) classification based on tumor CD274 (PD-L1) expression status and tumor-infiltrating lymphocytes in colorectal carcinomas.
Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance.
Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial.
Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.
Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.
An integrated map of structural variation in 2,504 human genomes.
Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms.
Erratum: analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms.
Pyruvate to Lactate Metabolic Changes during Neurodevelopment Measured Dynamically Using Hyperpolarized 13C Imaging in Juvenile Murine Brain.
FunSeq2: a framework for prioritizing noncoding regulatory variants in cancer.
Integrative annotation of variants from 1092 humans: application to cancer genomics.
The origin, evolution, and functional impact of short insertion-deletion variants identified in 179 human genomes.
A systematic survey of loss-of-function variants in human protein-coding genes.
Architecture of the human regulatory network derived from ENCODE data.
The GENCODE pseudogene resource.
Analysis of genomic variation in non-coding elements using population-scale sequencing data from the 1000 Genomes Project.
Genomics and privacy: implications of the new reality of closed data for the field.
Mapping copy number variation by population-scale genome sequencing.
The real cost of sequencing: higher than you think!
Nucleotide-resolution analysis of structural variants using BreakSeq and a breakpoint library.
PEMer: a computational framework with simulation-based error models for inferring genomic structural variants from massive paired-end sequencing data.
Interleukin-29 functions cooperatively with interferon to induce antiviral gene expression and inhibit hepatitis C virus replication.
