Steven Hetts, MD

Professor
Co-Director, Image-Guided Surgery SRG
PROF IN RES-HCOMP

Biography

Steven Hetts, MD is Chief of Interventional Neuroradiology at the UCSF Mission Bay Hospitals, where he provides cutting-edge, minimally invasive endovascular therapy for children and adults with stroke, cerebrovascular disease and tumors, including retinoblastoma. He founded the Interventional Neuroradiology services at San Francisco General Hospital and the San Francisco Veteran’s Administration Hospital, where he served as Chief until 2015. Throughout his career, Dr. Hetts has maintained an active clinical practice at UCSF Parnassus, treating patients with stroke, brain aneurysms, arteriovenous malformations, dural arteriovenous fistulas, spinal vascular malformations, and tumors including meningioma. Dr. Hetts is also the founding Co-Director of the UCSF Hereditary Hemorrhagic Telangiectasia Center of Excellence wherein he and his colleagues provide care for patients with vascular malformations of the brain, severe nosebleeds (epistaxis), and arteriovenous malformations of the lung and other organs. Dr. Hetts received his MD from Harvard Medical School and his undergraduate degree from Harvard College. He completed his medical internship at Stanford and his diagnostic radiology residency, diagnostic neuroradiology fellowship, and interventional neuroradiology fellowship at UCSF, where he joined the faculty in 2008.

As Co-Director of the Interventional Radiology Research Laboratory, Dr. Hetts is involved in translating basic science and engineering research into clinical applicability. The main theme of his research is development of novel image-guided endovascular devices and techniques for the treatment of stroke, tumors, vascular malformations, and other conditions accessible through the blood vessels or skin. He has been the principal investigator on an NIH-sponsored project to develop remote-controlled endovascular catheters for use in interventional MRI. This could revolutionize stroke treatment, allowing doctors to visualize living versus dead brain tissue in real-time during their surgeries. He is also the principal investigator on an NIH-sponsored project to develop an endovascular filtration device to reduce systemic toxicity during intraarterial chemotherapy for a variety of tumors. Such a device could not only reduce the side-effects of chemotherapy, but also enable better tumor control and, in some cases, cure. Dr. Hetts’ research projects have received over $4.5 million in federal and foundation funding and he was appointed chair of an NIH study section evaluating innovative neurological technologies in 2016.

Dr. Hetts has published over 130 peer-reviewed articles and book chapters. He has lectured on interventional neuroradiology clinical practice and research on six continents. With colleagues in the IR Research Lab, Dr. Hetts helped form a startup company, ChemoFilter, to develop endovascular filtration devices. This company was nominated for Medical Device Startup Company of the Year in the First Annual California Quantitative Biology Awards in 2015 and was acquired that year by Penumbra, Inc, an Alameda-based maker of endovascular devices. In 2015, Dr. Hetts was named a Fellow of the Rosenman institute at QB3 and advises other UCSF faculty and affiliates on developing translational research to bring innovative ideas to patient care.

Expertise:
Neuro Interventional Radiology

Specialty:
Brain, spine, head and neck

Professional Interests:
Interventional neuroradiology, neurointerventional radiology, neurointerventional surgery, pediatric neuroradiology, diagnostic neuroradiology, interventional MRI, interventional neuro-oncology

Education and Training:
• Medical School: Harvard Medical School, Boston, Massachusetts
• Internship: Stanford University, California - Internal Medicine
• Residency: University of California, San Francisco - Diagnostic Radiology
• Fellowship: University of California, San Francisco - Diagnostic Neuroradiology
• Fellowship: University of California, San Francisco - Interventional Neuroradiology
• Physician and Surgeon, Medical Board of California
• Radiology X-Ray Supervisor and Operator, California Department of Health Services
• Board Certified in Diagnostic Radiology, American Board of Radiology
• Subspecialty Certification (CAQ) in Neuroradiology, American Board of Radiology
• Basic Life Support Certification (BLS), American Heart Association
• Advanced Cardiac Life Support Certification (ACLS), American Heart Association

Education

M.D., 2000 - School of Medicine, Harvard University
Fellowship, - School of Medicine - Diagnostic Neuroradiology, University of California, San Francisco
Fellowship, - School of Medicine - Interventional Neuroradiology, University of California, San Francisco
Residency, - School of Medicine - Radiology, University of California, San Francisco

Honors and Awards

"I am a UC Entrepreneur" Award, ChemoFilter Device, University of California, San Francisco, 2017
Distinguished Investigator Award, Academy for Radiology and Biomedical Imaging Research, 2017
Robert I. White Young Clinician Award for Outstanding Contributions to HHT Care, Cure HHT International Foundation, 2017
Health Exceptional Physician Award, University of California, San Francisco, 2017
Excellence in Medical Student Teaching Award, UCSF Department of Radiology and Biomedical Imaging, 2016
Catalyst Award, University of California, San Francisco, 2016
Nominee, Best Medical Device Start-Up Company, ChemoFilter, California Institute for Quantitative Biosciences (QB3), 2015
Fellow, Rosenman Institute for Medical Device Innovation, 2015
Catalyst Award, University of California, San Francisco, 2013
Neuroradiology Education and Research Foundation Scholar Award in Neuroradiology Research, American Society of Neuroradiology, 2011
First Prize Poster, Interventional Category, International Society for Magnetic Resonance in Medicine Annual Meeting, Montreal, Canada, 2011
Neuroradiology Education and Research Foundation Scholar Award, American Society of Neuroradiology, 2010
Executive Council Award, Residents in Radiology Competition, American Roentgen Ray Society, 2005
Annual Research Award, American Society of Pediatric Neuroradiology, 2004
Resident Research Award, Margulis Society Radiology, 2002-2003
Nominee, Resident Teaching Award, Department of Internal Medicine, Stanford Hospital, 2001
Ebert Community Service Award, Harvard Medical School, 1997

Publications

Maani N, Hetts SW, Rayz VL. A two-scale approach for CFD modeling of endovascular Chemofilter device. Biomech Model Mechanobiol. 2018 Jul 31.
Blumenfeld CM, Schulz MD, Aboian MS, Wilson MW, Moore T, Hetts SW, Grubbs RH. Drug capture materials based on genomic DNA-functionalized magnetic nanoparticles. Nat Commun. 2018 Jul 20; 9(1):2870.
Lee SK, Mokin M, Hetts SW, Fifi JT, Bousser MG, Fraser JF. Current endovascular strategies for cerebral venous thrombosis: report of the SNIS Standards and Guidelines Committee. J Neurointerv Surg. 2018 Jun 05.
Jordan CD, Han M, Kondapavulur S, Vera DB, Neumann KD, Moore T, Stillson C, Krug R, Behr S, Seo Y, VanBrocklin HF, Larson PEZ, Wilson M, Martin AJ, Hetts SW. Quantification of 89 Zr-Iron oxide nanoparticle biodistribution using PET-MR and ultrashort TE sequences. J Magn Reson Imaging. 2018 May 14.
Talbott JF, Cooke DL, Mabray MC, Larson PS, Amans MR, Hetts SW, Wilson MW, Moore T, Salegio EA. Accuracy of image-guided percutaneous injection into a phantom spinal cord utilizing flat panel detector CT with MR fusion and integrated navigational software. J Neurointerv Surg. 2018 Apr 17.
LaHue SC, Kim H, Pawlikowska L, Nelson J, Cooke DL, Hetts SW, Singh V. Frequency and characteristics associated with inherited thrombophilia in patients with intracranial dural arteriovenous fistula. J Neurosurg. 2018 Apr 06; 1-5.
Alexander MD, Hippe DS, Cooke DL, Hallam DK, Hetts SW, Kim H, Lawton MT, Sekhar LN, Kim LJ, Ghodke BV. Targeted Embolization of Aneurysms Associated With Brain Arteriovenous Malformations at High Risk for Surgical Resection: A Case-Control Study. Neurosurgery. 2018 Mar 01; 82(3):343-349.
McGregor HCJ, Surman A, Fernandez A, Saeed M, Wilson M, Hetts S, Conrad M. Pilot Study of the Safety and Efficacy of Gallbladder Cryoablation in a Porcine Model: Midterm Results. J Vasc Interv Radiol. 2018 Mar; 29(3):340-344.
Kondapavulur S, Cooke DL, Kao A, Amans MR, Alexander M, Darflinger R, Dowd CF, Higashida RT, Damato B, Halbach VV, Matthay KK, Hetts SW. Estimation of intra-arterial chemotherapy distribution to the retina in pediatric retinoblastoma patients using quantitative digital subtraction angiography. Interv Neuroradiol. 2018 Apr; 24(2):214-219.
Yu JF, Nicholson AD, Nelson J, Alexander MD, Tse SH, Hetts SW, Hemphill JC, Kim H, Cooke DL. Predictors of intracranial hemorrhage volume and distribution in brain arteriovenous malformation. Interv Neuroradiol. 2018 Apr; 24(2):183-188.
Gandhi CD, Al Mufti F, Singh IP, Abruzzo T, Albani B, Ansari SA, Arthur AS, Bain M, Baxter BW, Bulsara KR, Caplan JM, Chen M, Dabus G, Frei D, Hetts SW, Hussain MS, Jayaraman MV, Kayan Y, Klucznik RP, Lee SK, Mack WJ, Leslie-Mazwi T, McTaggart RA, Meyers PM, Mokin M, Patsalides AT, Prestigiacomo CJ, Pride GL, Starke RM, Sunenshine PJ, Fraser JF. Neuroendovascular management of emergent large vessel occlusion: update on the technical aspects and standards of practice by the Standards and Guidelines Committee of the Society of NeuroInterventional Surgery. J Neurointerv Surg. 2018 Mar; 10(3):315-320.
Ammanuel S, Alexander MD, Damato B, Cooke DL, Halbach VV, Amans MR, Dowd CF, Higashida RT, Hetts SW. Improved procedural safety following protocol changes for selective ophthalmic arterial infusion of chemotherapy for treatment of ocular retinoblastoma. Interv Neuroradiol. 2018 Jan 01; 1591019918755088.
Meybodi AT, Kim H, Nelson J, Hetts SW, Krings T, terBrugge KG, Faughnan ME, Lawton MT. Surgical Treatment vs Nonsurgical Treatment for Brain Arteriovenous Malformations in Patients with Hereditary Hemorrhagic Telangiectasia: A Retrospective Multicenter Consortium Study. Neurosurgery. 2018 Jan 01; 82(1):35-47.
Alexander MD, Rebhun JM, Hetts SW, Amans MR, Settecase F, Darflinger RJ, Dowd CF, Halbach VV, Higashida RT, Cooke DL. Technical factors affecting outcomes following endovascular treatment of posterior circulation atherosclerotic lesions. Surg Neurol Int. 2017; 8:284.
Settecase F, McCoy DB, Darflinger R, Alexander MD, Cooke DL, Dowd CF, Hetts SW, Higashida RT, Halbach VV, Amans MR. Improving mechanical thrombectomy time metrics in the angiography suite: Stroke cart, parallel workflows, and conscious sedation. Interv Neuroradiol. 2018 Apr; 24(2):168-177.
Leslie-Mazwi T, Chen M, Yi J, Starke RM, Hussain MS, Meyers PM, McTaggart RA, Pride GL, Ansari AS, Abruzzo T, Albani B, Arthur AS, Baxter BW, Bulsara KR, Delgado Almandoz JE, Gandhi CD, Heck D, Hetts SW, Klucznik RP, Jayaraman MV, Lee SK, Mack WJ, Mocco J, Prestigiacomo C, Patsalides A, Rasmussen P, Sunenshine P, Frei D, Fraser JF. Post-thrombectomy management of the ELVO patient: Guidelines from the Society of NeuroInterventional Surgery. J Neurointerv Surg. 2017 12; 9(12):1258-1266.
Hetts SW, Yen A, Cooke DL, Nelson J, Jolivalt P, Banaga J, Amans MR, Dowd CF, Higashida RT, Lawton MT, Kim H, Halbach VV. Pial Artery Supply as an Anatomic Risk Factor for Ischemic Stroke in the Treatment of Intracranial Dural Arteriovenous Fistulas. AJNR Am J Neuroradiol. 2017 Dec; 38(12):2315-2320.
Yang JK, Cote AM, Jordan CD, Kondapavulur S, Losey AD, McCoy D, Chu A, Yu JF, Moore T, Stillson C, Settecase F, Alexander MD, Nicholson A, Cooke DL, Saeed M, Barry D, Martin AJ, Wilson MW, Hetts SW. Interventional magnetic resonance imaging guided carotid embolectomy using a novel resonant marker catheter: demonstration of preclinical feasibility. Biomed Microdevices. 2017 Sep 25; 19(4):88.
Cooke DL, McCoy DB, Halbach VV, Hetts SW, Amans MR, Dowd CF, Higashida RT, Lawson D, Nelson J, Wang CY, Kim H, Werb Z, McCulloch C, Hashimoto T, Su H, Sun Z. Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis. Transl Stroke Res. 2018 Feb; 9(1):20-33.
Jovin TG, Saver JL, Ribo M, Pereira V, Furlan A, Bonafe A, Baxter B, Gupta R, Lopes D, Jansen O, Smith W, Gress D, Hetts S, Lewis RJ, Shields R, Berry SM, Graves TL, Malisch T, Rai A, Sheth KN, Liebeskind DS, Nogueira RG. Diffusion-weighted imaging or computerized tomography perfusion assessment with clinical mismatch in the triage of wake up and late presenting strokes undergoing neurointervention with Trevo (DAWN) trial methods. Int J Stroke. 2017 08; 12(6):641-652.
Zhang X, Martin A, Jordan C, Lillaney P, Losey A, Pang Y, Hu J, Wilson M, Cooke D, Hetts SW. Design of catheter radio frequency coils using coaxial transmission line resonators for interventional neurovascular MR imaging. Quant Imaging Med Surg. 2017 Apr; 7(2):187-194.
Aboian MS, Yu JF, Gautam A, Sze CH, Yang JK, Chan J, Lillaney PV, Jordan CD, Oh HJ, Wilson DM, Patel AS, Wilson MW, Hetts SW. In vitro clearance of doxorubicin with a DNA-based filtration device designed for intravascular use with intra-arterial chemotherapy. Biomed Microdevices. 2016 12; 18(6):98.
Kondapavulur S, Cote AM, Neumann KD, Jordan CD, McCoy D, Mabray MC, Liu D, Sze CH, Gautam A, VanBrocklin HF, Wilson M, Hetts SW. Optimization of an endovascular magnetic filter for maximized capture of magnetic nanoparticles. Biomed Microdevices. 2016 12; 18(6):109.
Ryu WHA, Avery MB, Dharampal N, Allen IE, Hetts SW. Utility of perfusion imaging in acute stroke treatment: a systematic review and meta-analysis. J Neurointerv Surg. 2017 Oct; 9(10):1012-1016.
Lum MA, Martin AJ, Alexander MD, McCoy DB, Cooke DL, Lillaney P, Moftakhar P, Amans MR, Settecase F, Nicholson A, Dowd CF, Halbach VV, Higashida RT, McDermott MW, Saloner D, Hetts SW. Intra-Arterial MR Perfusion Imaging of Meningiomas: Comparison to Digital Subtraction Angiography and Intravenous MR Perfusion Imaging. PLoS One. 2016; 11(11):e0163554.
Pride GL, Fraser JF, Gupta R, Alberts MJ, Rutledge JN, Fowler R, Ansari SA, Abruzzo T, Albani B, Arthur A, Baxter B, Bulsara KR, Chen M, Delgado Almandoz JE, Gandhi CD, Heck D, Hetts SW, Hirsch JA, Hussain MS, Klucznik R, Lee SK, Mack WJ, Leslie-Mazwi T, McTaggart RA, Meyers PM, Mocco J, Prestigiacomo C, Patsalides A, Rasmussen P, Starke RM, Sunenshine P, Frei D, Jayaraman MV. Prehospital care delivery and triage of stroke with emergent large vessel occlusion (ELVO): report of the Standards and Guidelines Committee of the Society of Neurointerventional Surgery. J Neurointerv Surg. 2017 08; 9(8):802-812.
Hetts SW, Moftakhar P, Maluste N, Fullerton HJ, Cooke DL, Amans MR, Dowd CF, Higashida RT, Halbach VV. Pediatric intracranial dural arteriovenous fistulas: age-related differences in clinical features, angioarchitecture, and treatment outcomes. J Neurosurg Pediatr. 2016 Nov; 18(5):602-610.
Chen XC, Oh HJ, Yu JF, Yang JK, Petzetakis N, Patel AS, Hetts SW, Balsara NP. Block Copolymer Membranes for Efficient Capture of a Chemotherapy Drug. ACS Macro Lett. 2016 Aug 16; 5(8):936-941.
De la Huerta I, Seider MI, Hetts SW, Damato BE. Delayed Cerebral Infarction Following Intra-arterial Chemotherapy for Retinoblastoma. JAMA Ophthalmol. 2016 06 01; 134(6):712-4.
McGregor HC, Saeed M, Surman A, Ehman EC, Hetts SW, Wilson MW, Conrad MB. Gallbladder Cryoablation: Proof of Concept in a Swine Model for a Percutaneous Alternative to Cholecystectomy. Cardiovasc Intervent Radiol. 2016 Jul; 39(7):1031-5.
Alexander MD, Cooke DL, Hallam DK, Kim H, Hetts SW, Ghodke BV. Less can be more: Targeted embolization of aneurysms associated with arteriovenous malformations unsuitable for surgical resection. Interv Neuroradiol. 2016 Aug; 22(4):445-51.
Lillaney PV, Yang JK, Losey AD, Martin AJ, Cooke DL, Thorne BR, Barry DC, Chu A, Stillson C, Do L, Arenson RL, Saeed M, Wilson MW, Hetts SW. Endovascular MR-guided Renal Embolization by Using a Magnetically Assisted Remote-controlled Catheter System. Radiology. 2016 10; 281(1):219-28.
Saeed M, Krug R, Do L, Hetts SW, Wilson MW. Renal ablation using magnetic resonance-guided high intensity focused ultrasound: Magnetic resonance imaging and histopathology assessment. World J Radiol. 2016 Mar 28; 8(3):298-307.
Kim S, Heller J, Iqbal Z, Kant R, Kim EJ, Durack J, Saeed M, Do L, Hetts S, Wilson M, Brakeman P, Fissell WH, Roy S. Preliminary Diffusive Clearance of Silicon Nanopore Membranes in a Parallel Plate Configuration for Renal Replacement Therapy. ASAIO J. 2016 Mar-Apr; 62(2):169-75.
Heit JJ, Do HM, Prestigiacomo CJ, Delgado-Almandoz JA, English J, Gandhi CD, Albuquerque FC, Narayanan S, Blackham KA, Abruzzo T, Albani B, Fraser JF, Heck DV, Hussain MS, Lee SK, Ansari SA, Hetts SW, Bulsara KR, Kelly M, Arthur AS, Patsalides A, Pride GL, Powers CJ, Alexander MJ, Meyers PM, Jayaraman MV. Guidelines and parameters: percutaneous sclerotherapy for the treatment of head and neck venous and lymphatic malformations. J Neurointerv Surg. 2017 06; 9(6):611-617.
Mabray MC, Lillaney P, Sze CH, Losey AD, Yang J, Kondapavulur S, Liu D, Saeed M, Patel A, Cooke D, Jun YW, El-Sayed I, Wilson M, Hetts SW. In Vitro Capture of Small Ferrous Particles with a Magnetic Filtration Device Designed for Intravascular Use with Intraarterial Chemotherapy: Proof-of-Concept Study. J Vasc Interv Radiol. 2016 Mar; 27(3):426-32.e1.
Lee SK, Hetts SW, Halbach V, terBrugge K, Ansari SA, Albani B, Abruzzo T, Arthur A, Alexander MJ, Albuquerque FC, Baxter B, Bulsara KR, Chen M, Delgado Almandoz JE, Fraser JF, Frei D, Gandhi CD, Heck D, Hussain MS, Kelly M, Klucznik R, Leslie-Mazwi T, McTaggart RA, Meyers PM, Patsalides A, Prestigiacomo C, Pride GL, Starke R, Sunenshine P, Rasmussen P, Jayaraman MV. Standard and Guidelines: Intracranial Dural Arteriovenous Shunts. J Neurointerv Surg. 2017 05; 9(5):516-523.
Settecase F, Nicholson AD, Amans MR, Higashida RT, Halbach VV, Cooke DL, Dowd CF, Hetts SW. Onyx embolization of an intraosseous pseudoaneurysm of the middle meningeal artery in a patient with meningiomatosis, McCune-Albright syndrome, and gray platelet syndrome. J Neurosurg Pediatr. 2016 Mar; 17(3):324-9.
Conrad MB, Ishaque BM, Surman AM, Kerlan RK, Hope MD, Dickey MA, Hetts SW, Wilson MW. Intraprocedural Safety and Technical Success of the MVP Micro Vascular Plug for Embolization of Pulmonary Arteriovenous Malformations. J Vasc Interv Radiol. 2015 Nov; 26(11):1735-9.
McTaggart RA, Ansari SA, Goyal M, Abruzzo TA, Albani B, Arthur AJ, Alexander MJ, Albuquerque FC, Baxter B, Bulsara KR, Chen M, Almandoz JE, Fraser JF, Frei D, Gandhi CD, Heck DV, Hetts SW, Hussain MS, Kelly M, Klucznik R, Lee SK, Leslie-Mawzi T, Meyers PM, Prestigiacomo CJ, Pride GL, Patsalides A, Starke RM, Sunenshine P, Rasmussen PA, Jayaraman MV. Initial hospital management of patients with emergent large vessel occlusion (ELVO): report of the standards and guidelines committee of the Society of NeuroInterventional Surgery. J Neurointerv Surg. 2017 Mar; 9(3):316-323.
Settecase F, Martin AJ, Lillaney P, Losey A, Hetts SW. Magnetic Resonance-Guided Passive Catheter Tracking for Endovascular Therapy. Magn Reson Imaging Clin N Am. 2015 Nov; 23(4):591-605.
Narvid J, Amans MR, Cooke DL, Hetts SW, Dillon WP, Higashida RT, Dowd CF, Halbach VV. Spontaneous retroclival hematoma: a case series. J Neurosurg. 2016 Mar; 124(3):716-9.
Saeed M, Van TA, Krug R, Hetts SW, Wilson MW. Cardiac MR imaging: current status and future direction. Cardiovasc Diagn Ther. 2015 Aug; 5(4):290-310.
Sun Z, Lawson DA, Sinclair E, Wang CY, Lai MD, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Werb Z, Su H, Cooke DL. Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels?. Biotechnol Rep (Amst). 2015 Sep; 7:157-165.
Hetts SW, Tsai T, Cooke DL, Amans MR, Settecase F, Moftakhar P, Dowd CF, Higashida RT, Lawton MT, Halbach VV. Progressive versus Nonprogressive Intracranial Dural Arteriovenous Fistulas: Characteristics and Outcomes. AJNR Am J Neuroradiol. 2015 Oct; 36(10):1912-9.
Moftakhar P, Lillaney P, Losey AD, Cooke DL, Martin AJ, Thorne BR, Arenson RL, Saeed M, Wilson MW, Hetts SW. New-Generation Laser-lithographed Dual-Axis Magnetically Assisted Remote-controlled Endovascular Catheter for Interventional MR Imaging: In Vitro Multiplanar Navigation at 1.5 T and 3 T versus X-ray Fluoroscopy. Radiology. 2015 Dec; 277(3):842-52.
Do L, Wilson MW, Krug R, Hetts SW, Saeed M. MRI monitoring of function, perfusion and viability in microembolized moderately ischemic myocardium. Int J Cardiovasc Imaging. 2015 Aug; 31(6):1179-90.
Alexander MD, Rebhun JM, Hetts SW, Kim AS, Nelson J, Kim H, Amans MR, Settecase F, Dowd CF, Halbach VV, Higashida RT, Cooke DL. Lesion location, stability, and pretreatment management: factors affecting outcomes of endovascular treatment for vertebrobasilar atherosclerosis. J Neurointerv Surg. 2016 May; 8(5):466-70.
Jayaraman MV, Hussain MS, Abruzzo T, Albani B, Albuquerque FC, Alexander MJ, Ansari SA, Arthur AS, Baxter B, Bulsara KR, Chen M, Delgado Almandoz JE, Delgado-Almandoz JA, Fraser JF, Heck DV, Hetts SW, Kelly M, Lee SK, Leslie-Mawzi T, McTaggart RA, Meyers PM, Prestigiacomo C, Pride GL, Patsalides A, Starke RM, Tarr RW, Frei D, Rasmussen P. Embolectomy for stroke with emergent large vessel occlusion (ELVO): report of the Standards and Guidelines Committee of the Society of NeuroInterventional Surgery. J Neurointerv Surg. 2015 May; 7(5):316-21.
Saeed M, Bajwa HZ, Do L, Hetts SW, Wilson MW. Multi-detector CT and MRI of microembolized myocardial infarct: monitoring of left ventricular function, perfusion, and myocardial viability in a swine model. Acta Radiol. 2016 Feb; 57(2):215-24.
Cooke DL, Bauer D, Sun Z, Stillson C, Nelson J, Barry D, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Su H, Saeed MM. Endovascular biopsy: Technical feasibility of novel endothelial cell harvesting devices assessed in a rabbit aneurysm model. Interv Neuroradiol. 2015 Feb; 21(1):120-8.
Moftakhar P, Cooke DL, Fullerton HJ, Ko NU, Amans MR, Narvid JA, Dowd CF, Higashida RT, Halbach VV, Hetts SW. Extent of collateralization predicting symptomatic cerebral vasospasm among pediatric patients: correlations among angiography, transcranial Doppler ultrasonography, and clinical findings. J Neurosurg Pediatr. 2015 Mar; 15(3):282-90.
Sun Z, Su H, Long B, Sinclair E, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Cooke DL. Endothelial cell high-enrichment from endovascular biopsy sample by laser capture microdissection and fluorescence activated cell sorting. J Biotechnol. 2014 Dec 20; 192 Pt A:34-9.
Saeed M, Hetts SW, Jablonowski R, Wilson MW. Magnetic resonance imaging and multi-detector computed tomography assessment of extracellular compartment in ischemic and non-ischemic myocardial pathologies. World J Cardiol. 2014 Nov 26; 6(11):1192-208.
Jablonowski R, Wilson MW, Do L, Hetts SW, Saeed M. Multidetector CT measurement of myocardial extracellular volume in acute patchy and contiguous infarction: validation with microscopic measurement. Radiology. 2015 Feb; 274(2):370-8.
Patel AS, Saeed M, Yee EJ, Yang J, Lam GJ, Losey AD, Lillaney PV, Thorne B, Chin AK, Malik S, Wilson MW, Chen XC, Balsara NP, Hetts SW. Development and Validation of Endovascular Chemotherapy Filter Device for Removing High-Dose Doxorubicin: Preclinical Study. J Med Device. 2014 Dec; 8(4):0410081-410088.
Jablonowski R, Wilson MW, Joudi N, Hetts SW, Saeed M. Three-dimensional MRI assessments of patchy and large myocardial infarction in beating and nonbeating swine hearts: validation with microscopy. Acad Radiol. 2014 Aug; 21(8):1048-55.
Gandhi CD, Bulsara KR, Fifi J, Kass-Hout T, Grant RA, Delgado Almandoz JE, English J, Meyers PM, Abruzzo T, Prestigiacomo CJ, Powers CJ, Lee SK, Albani B, Do HM, Eskey CJ, Patsalides A, Hetts S, Hussain MS, Ansari SA, Hirsch JA, Kelly M, Rasmussen P, Mack W, Pride GL, Alexander MJ, Jayaraman MV. Platelet function inhibitors and platelet function testing in neurointerventional procedures. J Neurointerv Surg. 2014 Oct; 6(8):567-77.
Cooke DL, Stout CE, Kim WT, Kansagra AP, Yu JP, Gu A, Jewell NP, Hetts SW, Higashida RT, Dowd CF, Halbach VV. Cerebral arterial fenestrations. Interv Neuroradiol. 2014 May-Jun; 20(3):261-74.
Martin AJ, Lillaney P, Saeed M, Losey AD, Settecase F, Evans L, Arenson RL, Wilson MW, Hetts SW. Digital subtraction MR angiography roadmapping for magnetic steerable catheter tracking. J Magn Reson Imaging. 2015 Apr; 41(4):1157-62.
Chow ML, Cooke DL, Fullerton HJ, Amans MR, Narvid J, Dowd CF, Higashida RT, Halbach VV, Hetts SW. Radiological and clinical features of vein of Galen malformations. J Neurointerv Surg. 2015 Jun; 7(6):443-8.
Bendjilali N, Nelson J, Weinsheimer S, Sidney S, Zaroff JG, Hetts SW, Segal M, Pawlikowska L, McCulloch CE, Young WL, Kim H. Common variants on 9p21.3 are associated with brain arteriovenous malformations with accompanying arterial aneurysms. J Neurol Neurosurg Psychiatry. 2014 Nov; 85(11):1280-3.
Potts MB, Sheth SA, Louie J, Smyth MD, Sneed PK, McDermott MW, Lawton MT, Young WL, Hetts SW, Fullerton HJ, Gupta N. Stereotactic radiosurgery at a low marginal dose for the treatment of pediatric arteriovenous malformations: obliteration, complications, and functional outcomes. J Neurosurg Pediatr. 2014 Jul; 14(1):1-11.
English JD, Hetts SW, El-Ali A, Kolli P, Do L, Wilson MW, Saeed M. A novel model of large vessel ischemic stroke in rabbits: microcatheter occlusion of the posterior cerebral artery. J Neurointerv Surg. 2015 May; 7(5):363-6.
Olorunsola OG, Kim SH, Chang R, Kuo YC, Hetts SW, Heller A, Kant R, Saeed M, Fissell WH, Roy S, Wilson MW. Imaging assessment of a portable hemodialysis device: detection of possible failure modes and monitoring of functional performance. Med Instrum (Luton). 2014 Mar 27; 2(2).
Potts MB, Jahangiri A, Jen M, Sneed PK, McDermott MW, Gupta N, Hetts SW, Young WL, Lawton MT. Deep arteriovenous malformations in the basal ganglia, thalamus, and insula: multimodality management, patient selection, and results. World Neurosurg. 2014 Sep-Oct; 82(3-4):386-94.
Hetts SW, Cooke DL, Nelson J, Gupta N, Fullerton H, Amans MR, Narvid JA, Moftakhar P, McSwain H, Dowd CF, Higashida RT, Halbach VV, Lawton MT, Kim H. Influence of patient age on angioarchitecture of brain arteriovenous malformations. AJNR Am J Neuroradiol. 2014 Jul; 35(7):1376-80.
Losey AD, Lillaney P, Martin AJ, Cooke DL, Wilson MW, Thorne BR, Sincic RS, Arenson RL, Saeed M, Hetts SW. Magnetically assisted remote-controlled endovascular catheter for interventional MR imaging: in vitro navigation at 1.5 T versus X-ray fluoroscopy. Radiology. 2014 Jun; 271(3):862-9.
Amans MR, Cooke DL, Vella M, Dowd CF, Halbach VV, Higashida RT, Hetts SW. Contrast staining on CT after DSA in ischemic stroke patients progresses to infarction and rarely hemorrhages. Interv Neuroradiol. 2014 Jan-Feb; 20(1):106-15.
Lillaney P, Caton C, Martin AJ, Losey AD, Evans L, Saeed M, Cooke DL, Wilson MW, Hetts SW. Comparing deflection measurements of a magnetically steerable catheter using optical imaging and MRI. Med Phys. 2014 Feb; 41(2):022305.
Sincic RS, Caton CJ, Lillaney P, Goodfriend S, Ni J, Martin AJ, Losey AD, Shah N, Yee EJ, Evans L, Malba V, Bernhardt AF, Settecase F, Cooke DL, Saeed M, Wilson MW, Hetts SW. System architecture for a magnetically guided endovascular microcatheter. Biomed Microdevices. 2014 Feb; 16(1):97-106.
Bajwa HZ, Do L, Suhail M, Hetts SW, Wilson MW, Saeed M. MRI demonstrates a decrease in myocardial infarct healing and increase in compensatory ventricular hypertrophy following mechanical microvascular obstruction. J Magn Reson Imaging. 2014 Oct; 40(4):906-14.
Potts MB, Shah JK, Molinaro AM, Blevins LS, Tyrrell JB, Kunwar S, Dowd CF, Hetts SW, Aghi MK. Cavernous and inferior petrosal sinus sampling and dynamic magnetic resonance imaging in the preoperative evaluation of Cushing's disease. J Neurooncol. 2014 Feb; 116(3):593-600.
Cooke DL, Stout CE, Kim WT, Hetts SW, Higashida RT, Halbach VV, Dowd CF, Gould RG. Radiation dose reduction in intra-arterial chemotherapy infusion for intraocular retinoblastoma. J Neurointerv Surg. 2014 Dec; 6(10):785-9.
Suhail MS, Wilson MW, Hetts SW, Saeed M. Magnetic resonance imaging characterization of circumferential and longitudinal strain under various coronary interventions in swine. World J Radiol. 2013 Dec 28; 5(12):472-83.
Hetts SW, English JD, Stiver SI, Singh V, Yee EJ, Cooke DL, Halbach VV. Bilateral cervical spinal dural arteriovenous fistulas with intracranial venous drainage mimicking a foramen magnum dural arteriovenous fistula. Interv Neuroradiol. 2013 Dec; 19(4):483-8.
Amans MR, Stout C, Fox C, Narvid J, Hetts SW, Cooke DL, Higashida RT, Dowd CF, McSwain H, Halbach VV. Cerebral arteriopathy associated with Arg179His ACTA2 mutation. J Neurointerv Surg. 2014 Nov; 6(9):e46.
Cooke DL, Su H, Sun Z, Guo Y, Guo D, Saeed MM, Hetts SW, Higashida RT, Dowd CF, Young WL, Halbach VV. Endovascular biopsy: evaluating the feasibility of harvesting endothelial cells using detachable coils. Interv Neuroradiol. 2013 Dec; 19(4):399-408.
Amans MR, Stout C, Fox C, Narvid J, Hetts SW, Cooke DL, Higashida RT, Dowd CF, McSwain H, Halbach VV. Cerebral arteriopathy associated with Arg179His ACTA2 mutation. BMJ Case Rep. 2013 Nov 29; 2013.
Saeed M, Hetts SW, Do L, Wilson MW. Assessment of microembolization associated with revascularization in acute myocardial infarction: MDCT cardiac perfusion and function study. Int J Cardiovasc Imaging. 2013 Dec; 29(8):1861-9.
Wintermark M, Sanelli PC, Albers GW, Bello JA, Derdeyn CP, Hetts SW, Johnson MH, Kidwell CS, Lev MH, Liebeskind DS, Rowley HA, Schaefer PW, Sunshine JL, Zaharchuk G, Meltzer CC. Imaging recommendations for acute stroke and transient ischemic attack patients: a joint statement by the American Society of Neuroradiology, the American College of Radiology and the Society of NeuroInterventional Surgery. J Am Coll Radiol. 2013 Nov; 10(11):828-32.
Sheth SA, Potts MB, Sneed PK, Young WL, Cooke DL, Gupta N, Hetts SW. Angiographic features help predict outcome after stereotactic radiosurgery for the treatment of pediatric arteriovenous malformations. Childs Nerv Syst. 2014 Feb; 30(2):241-7.
Wilson MW, Martin AB, Lillaney P, Losey AD, Yee EJ, Bernhardt A, Malba V, Evans L, Sincic R, Saeed M, Arenson RL, Hetts SW. Magnetic catheter manipulation in the interventional MR imaging environment. J Vasc Interv Radiol. 2013 Jun; 24(6):885-91.
Thampi S, Hetts SW, Cooke DL, Stewart PJ, Robbins E, Banerjee A, Dubois SG, Char D, Halbach V, Matthay K. Superselective intra-arterial melphalan therapy for newly diagnosed and refractory retinoblastoma: results from a single institution. Clin Ophthalmol. 2013; 7:981-9.
Losey AD, Lillaney P, Martin AJ, Halbach VV, Cooke DL, Dowd CF, Higashida RT, Saloner DA, Wilson MW, Saeed M, Hetts SW. Safety of retained microcatheters: an evaluation of radiofrequency heating in endovascular microcatheters with nitinol, tungsten, and polyetheretherketone braiding at 1.5 T and 3 T. J Neurointerv Surg. 2014 May; 6(4):314-9.
Saeed M, Hetts SW, Do L, Wilson MW. Coronary microemboli effects in preexisting acute infarcts in a swine model: cardiac MR imaging indices, injury biomarkers, and histopathologic assessment. Radiology. 2013 Jul; 268(1):98-108.
Hetts SW, Saeed M, Martin A, Lillaney P, Losey A, Yee EJ, Sincic R, Do L, Evans L, Malba V, Bernhardt AF, Wilson MW, Patel A, Arenson RL, Caton C, Cooke DL. Magnetically-Assisted Remote Controlled Microcatheter Tip Deflection under Magnetic Resonance Imaging. J Vis Exp. 2013 Apr 04; (74).
Alexander MD, English J, Hetts SW. Occipital artery anastomosis to vertebral artery causing pulsatile tinnitus. J Neurointerv Surg. 2014 Mar; 6(2):e15.
Alexander MD, English J, Hetts SW. Occipital artery anastomosis to vertebral artery causing pulsatile tinnitus. BMJ Case Rep. 2013 Mar 06; 2013.
Kansagra AP, Cooke DL, English JD, Sincic RM, Amans MR, Dowd CF, Halbach VV, Higashida RT, Hetts SW. Current trends in endovascular management of traumatic cerebrovascular injury. J Neurointerv Surg. 2014 Jan; 6(1):47-50.
Moftakhar P, English JD, Cooke DL, Kim WT, Stout C, Smith WS, Dowd CF, Higashida RT, Halbach VV, Hetts SW. Density of thrombus on admission CT predicts revascularization efficacy in large vessel occlusion acute ischemic stroke. Stroke. 2013 Jan; 44(1):243-5.
Saeed M, Hetts SW, Do L, Sullivan SM, Wilson MW. MRI quantification of left ventricular function in microinfarct versus large infarct in swine model. Int J Cardiovasc Imaging. 2013 Jan; 29(1):159-68.
Saeed M, Hetts SW, Do L, Sullivan S, Wilson MW. MDCT has the potential to predict percutaneous coronary intervention outcome in swine model: microscopic validation. Acta Radiol. 2012 Nov 01; 53(9):987-94.
Hetts SW, Mong S, Sincic R, English JD, Wilson MW. Delayed transcutaneous extrusion of embolic coils after embolization of facial artery pseudoaneurysm. Interv Neuroradiol. 2012 Sep; 18(3):353-7.
Moftakhar P, Hetts SW, Ko NU. Vascular myelopathies. Semin Neurol. 2012 Apr; 32(2):146-53.
Hetts SW, Keenan K, Fullerton HJ, Young WL, English JD, Gupta N, Dowd CF, Higashida RT, Lawton MT, Halbach VV. Pediatric intracranial nongalenic pial arteriovenous fistulas: clinical features, angioarchitecture, and outcomes. AJNR Am J Neuroradiol. 2012 Oct; 33(9):1710-9.
Muller L, Saeed M, Wilson MW, Hetts SW. Remote control catheter navigation: options for guidance under MRI. J Cardiovasc Magn Reson. 2012 Jun 01; 14:33.
Toossi S, Josephson SA, Hetts SW, Chin CT, Kralik S, Jun P, Douglas VC. Utility of MRI in spinal arteriovenous fistula. Neurology. 2012 Jul 03; 79(1):25-30.
Hetts SW, Moftakhar P, English JD, Dowd CF, Higashida RT, Lawton MT, Douglas VC, Halbach VV. Spinal dural arteriovenous fistulas and intrathecal venous drainage: correlation between digital subtraction angiography, magnetic resonance imaging, and clinical findings. J Neurosurg Spine. 2012 May; 16(5):433-40.
Guo Y, Saunders T, Su H, Kim H, Akkoc D, Saloner DA, Hetts SW, Hess C, Lawton MT, Bollen AW, Pourmohamad T, McCulloch CE, Tihan T, Young WL. Silent intralesional microhemorrhage as a risk factor for brain arteriovenous malformation rupture. Stroke. 2012 May; 43(5):1240-6.
Saeed M, Hetts SW, Ursell PC, Do L, Kolli KP, Wilson MW. Evaluation of the acute effects of distal coronary microembolization using multidetector computed tomography and magnetic resonance imaging. Magn Reson Med. 2012 Jun; 67(6):1747-57.
Alexander MD, Hetts SW, Young WL, Halbach VV, Dowd CF, Higashida RT, English JD. Supernova hemorrhage: obliterative hemorrhage of brain arteriovenous malformations following ? knife radiosurgery. J Neurointerv Surg. 2012 Sep; 4(5):364-7.
Saeed M, Hetts SW, Do L, Wilson MW. MRI study on volume effects of coronary emboli on myocardial function, perfusion and viability. Int J Cardiol. 2013 Apr 30; 165(1):93-9.
Saeed M, Hetts SW, English J, Wilson M. MR fluoroscopy in vascular and cardiac interventions (review). Int J Cardiovasc Imaging. 2012 Jan; 28(1):117-37.
Saeed M, Hetts SW, English J, Do L, Wilson MW. Quantitative and qualitative characterization of the acute changes in myocardial structure and function after distal coronary microembolization using MDCT. Acad Radiol. 2011 Apr; 18(4):479-87.
Waldron JS, Sughrue ME, Hetts SW, Wilson SP, Mills SA, McDermott MW, Dowd CF, Parsa AT. Embolization of skull base meningiomas and feeding vessels arising from the internal carotid circulation. Neurosurgery. 2011 Jan; 68(1):162-9; discussion 169.
Settecase F, Hetts SW, Martin AJ, Roberts TP, Bernhardt AF, Evans L, Malba V, Saeed M, Arenson RL, Kucharzyk W, Wilson MW. RF Heating of MRI-Assisted Catheter Steering Coils for Interventional MRI. Acad Radiol. 2011 Mar; 18(3):277-85.
Bernhardt A, Wilson MW, Settecase F, Evans L, Malba V, Martin AJ, Saeed M, Roberts TP, Arenson RL, Hetts SW. Steerable catheter microcoils for interventional MRI reducing resistive heating. Acad Radiol. 2011 Mar; 18(3):270-6.
Hetts SW, English JD. Acute neurointerventional therapies. Neuroimaging Clin N Am. 2010 Nov; 20(4):493-510.
Jian BJ, Hetts SW, Lawton MT, Gupta N. Pediatric intracranial aneurysms. Neurosurg Clin N Am. 2010 Jul; 21(3):491-501.
Saeed M, Hetts S, Wilson M. Reperfusion injury components and manifestations determined by cardiovascular MR and MDCT imaging. World J Radiol. 2010 Jan 28; 2(1):1-14.
Waldron JS, Hetts SW, Armstrong-Wells J, Dowd CF, Fullerton HJ, Gupta N, Lawton MT. Multiple intracranial aneurysms and moyamoya disease associated with microcephalic osteodysplastic primordial dwarfism type II: surgical considerations. J Neurosurg Pediatr. 2009 Nov; 4(5):439-44.
Racine CA, Lawton MT, Hetts SW, Josephson SA. Neuropyschological profile of reversible cognitive impairment in a patient with a dural arteriovenous fistula. Neurocase. 2008; 14(3):231-8.
Narvid J, Hetts SW, Larsen D, Neuhaus J, Singh TP, McSwain H, Lawton MT, Dowd CF, Higashida RT, Halbach VV. Spinal dural arteriovenous fistulae: clinical features and long-term results. Neurosurgery. 2008 Jan; 62(1):159-66; discussion 166-7.
Settecase F, Sussman MS, Wilson MW, Hetts S, Arenson RL, Malba V, Bernhardt AF, Kucharczyk W, Roberts TP. Magnetically-assisted remote control (MARC) steering of endovascular catheters for interventional MRI: a model for deflection and design implications. Med Phys. 2007 Aug; 34(8):3135-42.
Hetts SW, Hilchey SD, Wilson R, Franc B. Case 110: Nonossifying fibroma. Radiology. 2007 Apr; 243(1):288-92.
Hetts SW, Sherr EH, Chao S, Gobuty S, Barkovich AJ. Anomalies of the corpus callosum: an MR analysis of the phenotypic spectrum of associated malformations. AJR Am J Roentgenol. 2006 Nov; 187(5):1343-8.
Hetts SW. The ACGME Residency Review Committee for Diagnostic Radiology: a resident's perspective. J Am Coll Radiol. 2005 Jun; 2(6):548-51.
Hetts SW, Urban JP, Quiñones-Hinojosa A, Joelson DW, Glastonbury CM. The shading sign in cerebral squamous cell metastases. AJR Am J Roentgenol. 2004 Apr; 182(4):1087-8.
Wang ZJ, Reddy GP, Gotway MB, Yeh BM, Hetts SW, Higgins CB. CT and MR imaging of pericardial disease. Radiographics. 2003 Oct; 23 Spec No:S167-80.