Paola Porcari, PhD

Specialist
Specialist

Publications

Porcari P, Miloushev V, Patel S, Peyear T, Berishaj M, Keshari KR. Increasing Infusion Times of Hyperpolarized [1-13C]Pyruvate in a Mouse Brain Maintain Lactate Generation and Approach Pseudo-Steady State Metabolism. Magn Reson Med. 2025 Nov 11.
Cheng H, Miller D, Southwell N, Porcari P, Fischer JL, Taylor I, Salbaum JM, Kappen C, Hu F, Yang C, Keshari KR, Gross SS, D'Aurelio M, Chen Q. Untargeted pixel-by-pixel metabolite ratio imaging as a novel tool for biomedical discovery in mass spectrometry imaging. Elife. 2025 Mar 18; 13.
Patel S, Porcari P, Coffee E, Kim N, Berishaj M, Peyear T, Zhang G, Keshari KR. Simultaneous noninvasive quantification of redox and downstream glycolytic fluxes reveals compartmentalized brain metabolism. Sci Adv. 2024 Dec 20; 10(51):eadr2058.
Cheng H, Miller D, Southwell N, Porcari P, Fischer JL, Taylor I, Michael Salbaum J, Kappen C, Hu F, Yang C, Keshari KR, Gross SS, D'Aurelio M, Chen Q. Untargeted Pixel-by-Pixel Imaging of Metabolite Ratio Pairs as a Novel Tool for Biomedical Discovery in Mass Spectrometry Imaging. bioRxiv. 2024 Dec 16.
Bagdatlioglu E, Porcari P, Greally E, Blamire AM, Straub VW. Cognitive impairment appears progressive in the mdx mouse. Neuromuscul Disord. 2020 05; 30(5):368-388.
Porcari P, Hall MG, Clark CA, Greally E, Straub V, Blamire AM. Time-dependent diffusion MRI as a probe of microstructural changes in a mouse model of Duchenne muscular dystrophy. NMR Biomed. 2020 05; 33(5):e4276.
Whittaker RG, Porcari P, Braz L, Williams TL, Schofield IS, Blamire AM. Functional magnetic resonance imaging of human motor unit fasciculation in amyotrophic lateral sclerosis. Ann Neurol. 2019 03; 85(3):455-459.
Porcari P, Hall MG, Clark CA, Greally E, Straub V, Blamire AM. The effects of ageing on mouse muscle microstructure: a comparative study of time-dependent diffusion MRI and histological assessment. NMR Biomed. 2018 03; 31(3).
Porcari P, Hegi ME, Lei H, Hamou MF, Vassallo I, Capuani S, Gruetter R, Mlynarik V. Early detection of human glioma sphere xenografts in mouse brain using diffusion MRI at 14.1 T. NMR Biomed. 2016 11; 29(11):1577-1589.
Canese R, Zoratto F, Altabella L, Porcari P, Mercurio L, de Pasquale F, Butti E, Martino G, Lacivita E, Leopoldo M, Laviola G, Adriani W. Persistent modification of forebrain networks and metabolism in rats following adolescent exposure to a 5-HT7 receptor agonist. Psychopharmacology (Berl). 2015 Jan; 232(1):75-89.
Porcari P, Capuani S, D'Amore E, Lecce M, La Bella A, Fasano F, Migneco LM, Campanella R, Maraviglia B, Pastore FS. In vivo 19F MR imaging and spectroscopy for the BNCT optimization. Appl Radiat Isot. 2009 Jul; 67(7-8 Suppl):S365-8.
Capuani S, Gili T, Bozzali M, Russo S, Porcari P, Cametti C, Muolo M, D'Amore E, Maraviglia B, Lazzarino G, Pastore FS. Boronophenylalanine uptake in C6 glioma model is dramatically increased by L-DOPA preloading. Appl Radiat Isot. 2009 Jul; 67(7-8 Suppl):S34-6.
Porcari P, Capuani S, D'Amore E, Lecce M, La Bella A, Fasano F, Campanella R, Migneco LM, Pastore FS, Maraviglia B. In vivo (19)F MRI and (19)F MRS of (19)F-labelled boronophenylalanine-fructose complex on a C6 rat glioma model to optimize boron neutron capture therapy (BNCT). Phys Med Biol. 2008 Dec 07; 53(23):6979-89.
Capuani S, Gili T, Bozzali M, Russo S, Porcari P, Cametti C, D'Amore E, Colasanti M, Venturini G, Maraviglia B, Lazzarino G, Pastore FS. L-DOPA preloading increases the uptake of borophenylalanine in C6 glioma rat model: a new strategy to improve BNCT efficacy. Int J Radiat Oncol Biol Phys. 2008 Oct 01; 72(2):562-7.
Capuani S, Porcari P, Fasano F, Campanella R, Maraviglia B. 10B-editing 1H-detection and 19F MRI strategies to optimize boron neutron capture therapy. Magn Reson Imaging. 2008 Sep; 26(7):987-93.
Porcari P, Capuani S, Campanella R, La Bella A, Migneco LM, Maraviglia B. Multi-nuclear MRS and 19F MRI of 19F-labelled and 10B-enriched p-boronophenylalanine-fructose complex to optimize boron neutron capture therapy: phantom studies at high magnetic fields. Phys Med Biol. 2006 Jun 21; 51(12):3141-54.