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Jennifer Yokoyama, PhD
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Publications
Jennifer Yokoyama, PhD's Publications
Aging activates escape of the silent X chromosome in the female mouse hippocampus.
Author Correction: Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.
BDNF Val66Met polymorphism moderates associations between physical activity and neurocognitive outcomes in older adults.
Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing.
DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.
Functional Connectivity Associations With Markers of Disease Progression in GRN Pathogenic Variant Carriers.
Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations.
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.
Neurodevelopment and neural environment inform Alzheimer's disease age at onset and phenotype.
Opposing role of phagocytic receptors MERTK and AXL in Progranulin deficient FTD.
Reduced levels of angiogenesis biomarkers predict increased symptom severity in Chinese Americans with Alzheimer's disease with demographic-specific effect.
Social exposome and brain health outcomes of dementia across Latin America.
The Role of Genomic-Informed Risk Assessments in Predicting Dementia Outcomes.
Variable and interactive effects of Sex, APOE ε4 and TREM2 on the deposition of tau in entorhinal and neocortical regions.
White matter hyperintensities and their impact in brain structure and function in alzheimer's disease and behavioral variant frontotemporal dementia across Latin America and the United States: a cross-sectional study.
An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome.
Asian Cohort for Alzheimer's Disease (ACAD) pilot study on genetic and non-genetic risk factors for Alzheimer's disease among Asian Americans and Canadians.
Assessing the lack of diversity in genetics research across neurodegenerative diseases: a systematic review of the GWAS Catalog and literature.
Assessing the lack of diversity in genetics research across neurodegenerative diseases: A systematic review of the GWAS Catalog and literature.
Author Correction: Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations.
Basal parasympathetic deficits in C9orf72 hexanucleotide repeat expansion carriers relate to smaller frontoinsula and thalamus volume and lower empathy.
Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations.
Brain clocks capture diversity and disparity in aging and dementia.
C9orf72 gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types.
Data stewardship in FTLD research: Investigator and research participant views.
Deciphering Distinct Genetic Risk Factors for FTLD-TDP Pathological Subtypes via Whole-Genome Sequencing.
Dementia risk reduction in the African context: Multi-national implementation of multimodal strategies to promote healthy brain aging in Africa (the Africa-FINGERS project).
DNA methylation age from peripheral blood predicts progression to Alzheimer's disease, white matter disease burden, and cortical atrophy.
Educational disparities in brain health and dementia across Latin America and the United States.
Eosinophilic myocarditis: systematic review.
Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease.
Expansion of highly interferon-responsive T cells in early-onset Alzheimer's disease.
Frontotemporal lobar degeneration targets brain regions linked to expression of recently evolved genes.
Gaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused research.
Genetic Contributions to Alzheimer's Disease and Frontotemporal Dementia in Admixed Latin American Populations.
Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia.
Inhalant Screening in Early Adolescence: Missed Opportunity to Prevent Escalation to Polysubstance Use and Related Consequences.
Large-scale network analysis of the cerebrospinal fluid proteome identifies molecular signatures of frontotemporal lobar degeneration.
Social determinants of health but not global genetic ancestry predict dementia prevalence in Latin America.
Structural inequality linked to brain volume and network dynamics in aging and dementia across the Americas.
The role of interferon signaling in neurodegeneration and neuropsychiatric disorders.
Variable and interactive effects of Sex, APOE ε4 and TREM2 on the deposition of tau in entorhinal and neocortical regions.
An ANXA11 P93S variant dysregulates TDP-43 and causes corticobasal syndrome.
C9orf72 gene networks in the human brain correlate with cortical thickness in C9-FTD and implicate vulnerable cell types.
Discovery of genomic loci associated with sleep apnea risk through multi-trait GWAS analysis with snoring.
Early-onset Alzheimer's disease explained by polygenic risk of late-onset disease?
Frontotemporal dementia presentation in patients with heterozygous p.H157Y variant of TREM2.
FTLD targets brain regions expressing recently evolved genes.
Gaps in clinical research in frontotemporal dementia: A call for diversity and disparities-focused research.
Genetic overlap between cortical brain morphometry and frontotemporal dementia risk.
Medium Roasting and Brewing Methods Differentially Modulate Global Metabolites, Lipids, Biogenic Amines, Minerals, and Antioxidant Capacity of Hawai'i-Grown Coffee (Coffea arabica).
Multi-ancestry meta-analysis and fine-mapping in Alzheimer's disease.
Network Connectivity Alterations across the MAPT Mutation Clinical Spectrum.
Prevalence, Timing, and Network Localization of Emergent Visual Creativity in Frontotemporal Dementia.
Role for cell death pathway in Alzheimer's disease.
Sex-specific effects of SNAP-25 genotype on verbal memory and Alzheimer's disease biomarkers in clinically normal older adults.
Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy.
The impacts of social determinants of health and cardiometabolic factors on cognitive and functional aging in Colombian underserved populations.
Treatment resistant depression in elderly.
Biomarkers for dementia in Latin American countries: Gaps and opportunities.
Candidate Epigenetic Biomarker of Cognitive Trajectory: The Chicken or the Egg?
Case Report: Novel CSF1R Variant in a Patient With Behavioral Variant Frontotemporal Dementia Syndrome With Prodromal Repetitive Scratching Behavior.
Classification of Alzheimer's disease and frontotemporal dementia using routine clinical and cognitive measures across multicentric underrepresented samples: A cross sectional observational study.
Differences in peripheral immune system gene expression in frontotemporal degeneration.
Dissecting the clinical heterogeneity of early-onset Alzheimer's disease.
Eosinophilic Myocarditis Presenting as Cardiac Tamponade: A Diagnostic Challenge.
Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease.
Genetic, Social, and Lifestyle Drivers of Healthy Aging and Longevity.
Increasing empathic concern relates to salience network hyperconnectivity in cognitively healthy older adults with elevated amyloid-β burden.
Race, Genetic Admixture, and Cognitive Performance in the Cuban Population.
Radiogenomics of C9orf72 Expansion Carriers Reveals Global Transposable Element Derepression and Enables Prediction of Thalamic Atrophy and Clinical Impairment.
Constraints on Cosmic Strings Using Data from the Third Advanced LIGO-Virgo Observing Run.
Genetic pleiotropy and the shared pathological features of corticobasal degeneration and progressive supranuclear palsy: a case report and a review of the literature.
Moving Toward Patient-Tailored Treatment in ALS and FTD: The Potential of Genomic Assessment as a Tool for Biological Discovery and Trial Recruitment.
p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR).
Personal Utility and Early Intervention in Alzheimer's Disease.
Sex-Specific Association of the X Chromosome With Cognitive Change and Tau Pathology in Aging and Alzheimer Disease.
SVIP is a molecular determinant of lysosomal dynamic stability, neurodegeneration and lifespan.
Systematic Review: Genetic, Neuroimaging, and Fluids Biomarkers for Frontotemporal Dementia Across Latin America Countries.
The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation Science.
The Role of Microglia in Inherited White-Matter Disorders and Connections to Frontotemporal Dementia.
TSC1 loss increases risk for tauopathy by inducing tau acetylation and preventing tau clearance via chaperone-mediated autophagy.
A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease.
Association Between Chronic Kidney Disease-Mineral Bone Disease (CKD-MBD) and Cognition in Children: Chronic Kidney Disease in Children (CKiD) Study.
Brain volumetric deficits in MAPT mutation carriers: a multisite study.
C9orf72, age at onset, and ancestry help discriminate behavioral from language variants in FTLD cohorts.
Lack of Association Between the CCR5-delta32 Polymorphism and Neurodegenerative Disorders.
Longevity Gene KLOTHO and Alzheimer Disease-A Better Fate for Individuals Who Carry APOE ε4.
No association between the COMT Val158Met polymorphism and cognitive training response in healthy Shanghai community-dwelling elderly individuals.
Non-coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases.
Prospects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA.
Response to Holstege et al.
The power of knowledge about dementia in Latin America across health professionals working on aging.
Alzheimer Disease-associated Cortical Atrophy Does not Differ Between Chinese and Whites.
Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders.
Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr).
Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia.
Genome sequencing for early-onset or atypical dementia: high diagnostic yield and frequent observation of multiple contributory alleles.
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.
Immunological signatures in frontotemporal lobar degeneration.
Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration.
Recent advances in the genetics of frontotemporal dementia.
The Radiogenomics of Late-onset Alzheimer Disease.
The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease.
C9orf72-FTD/ALS pathogenesis: evidence from human neuropathological studies.
Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
CXCR4 involvement in neurodegenerative diseases.
Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease.
Frequency of frontotemporal dementia gene variants in C9ORF72, MAPT, and GRN in academic versus commercial laboratory cohorts.
Genetic Variation in the Androgen Receptor and Measures of Plasma Testosterone Levels Suggest Androgen Dysfunction in Alzheimer's Disease.
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
Insulin-Like Growth Factor Binding Protein 2 Is Associated With Biomarkers of Alzheimer's Disease Pathology and Shows Differential Expression in Transgenic Mice.
Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases.
Neurotransmitter Pathway Genes in Cognitive Decline During Aging: Evidence for GNG4 and KCNQ2 Genes.
Prospects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA.
Protein network analysis reveals selectively vulnerable regions and biological processes in FTD.
Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia.
Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex.
Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum.
Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study.
Full-layer mucosal histology in achalasia: Histological epithelial wave is characteristic in "pinstripe pattern"-positive achalasia.
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Genome-wide association study identifies MAPT locus influencing human plasma tau levels.
Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer's disease.
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia.
Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging.
Youthful Processing Speed in Older Adults: Genetic, Biological, and Behavioral Predictors of Cognitive Processing Speed Trajectories in Aging.
Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease.
Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease.
Association of Alzheimer Disease Susceptibility Variants and Gene Expression in the Human Brain-Reply.
Gene-based aggregate SNP associations between candidate AD genes and cognitive decline.
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases.
Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture.
Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression.
The relationship between complement factor C3, APOE ε4, amyloid and tau in Alzheimer's disease.
Amyloid in dementia associated with familial FTLD: not an innocent bystander.
APOE Genotype Affects Cognitive Training Response in Healthy Shanghai Community-Dwelling Elderly Individuals.
Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults.
Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer's disease.
The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia.
Variation in longevity gene KLOTHO is associated with greater cortical volumes.
Altered network connectivity in frontotemporal dementia with C9orf72 hexanucleotide repeat expansion.
C9ORF72 hexanucleotide repeats in behavioral and motor neuron disease: clinical heterogeneity and pathological diversity.
Damage to left frontal regulatory circuits produces greater positive emotional reactivity in frontotemporal dementia.
Genetic modifiers of cognitive maintenance among older adults.
Life extension factor klotho enhances cognition.
The Chinese Verbal Learning Test specifically assesses hippocampal state.
Depressive symptoms in Chinese-American subjects with cognitive impairment.
Heightened emotional contagion in mild cognitive impairment and Alzheimer's disease is associated with temporal lobe degeneration.
Mitochondrial DNA sequence associations with dementia and amyloid-β in elderly African Americans.
Progranulin mutations as risk factors for Alzheimer disease.
Atypical, slowly progressive behavioural variant frontotemporal dementia associated with C9ORF72 hexanucleotide expansion.
Frontotemporal dementia due to C9ORF72 mutations: clinical and imaging features.
Frontotemporal dementia in a Brazilian kindred with the c9orf72 mutation.
Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderly.
Mitochondrial DNA sequence variation is associated with free-living activity energy expenditure in the elderly.
Neuroimaging features of C9ORF72 expansion.
Variation in genes related to cochlear biology is strongly associated with adult-onset deafness in border collies.
A genomewide association study of citalopram response in major depressive disorder.
Array-based whole-genome survey of dog saliva DNA yields high quality SNP data.
Antitumor therapy mediated by 5-fluorocytosine and a recombinant fusion protein containing TSG-6 hyaluronan binding domain and yeast cytosine deaminase.
Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies.
Activation of cerebellar parallel fibers monitored in transgenic mice expressing a fluorescent Ca2+ indicator protein.
Pollination mode in fig wasps: the predictive power of correlated traits.
[Significance of interferon alpha therapy for advanced renal cell carcinoma. Fukushima Renal Cancer Study Group].
Effects of granisetron in children undergoing high-dose chemotherapy: a multi-institutional, cross-over study.
Impaired expression of neural cell adhesion molecule L1 in the extrinsic nerve fibers in Hirschsprung's disease.
Morphological, physiological and molecular genetic characterization ofArabidopsis himalaica, with reference toA. thaliana.
Problems in diagnosis of Hirschsprung's disease by anorectal manometry.
[Colostomy in children with special reference to postoperative courses].
[Colostomy in the pediatric patient].
