Jason Talbott, MD, PhD

Associate Professor
Associate Residency Program Director
Assistant Professor

Biography

Jason Talbott, MD, PhD, is an Associate Professor in Residence in the Neuroradiology section in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco and Zuckerberg San Francisco General Hospital. He also serves as Associate Residency Program Director. He earned his MD and PhD degrees from the University of Louisville, Kentucky, in 2007. He completed a one-year internship in Internal Medicine from the California Pacific Medical Center in San Francisco. From 2008-2012, Dr. Talbott completed a four-year Diagnostic Radiology residency at UCSF, followed by a one-year fellowship in Neuroradiology from UCSF, in 2013.

In 2012, as a resident, Dr. Talbott received the Alexander Margulis Outstanding Resident Research Award and also served as a Chief Resident in the Department of Radiology at UCSF. Dr. Talbott currently serves as the Associate Program Director for the Radiology residency program and chairs the Residency Selection Committee.

Research interests include advanced spinal cord and degenerative spine imaging. As part of a multi-disciplinary clinical team at Zuckerberg San Francisco General Hospital, Dr. Talbott is active in multiple SCI trials as part of the Transforming Research and Clinical Knowledge in Spinal Cord Injury (TRACK-SCI) initiative. Dr. Talbott has published more than 50 peer-reviewed articles in addition to numerous book chapters and review articles.

Expertise:
Neuroradiology

Specialty:
Spinal cord

Professional Interests:
Spinal cord and brain trauma

Education and Training:
• Medical School: University of Louisville, Kentucky
• Internship: California Pacific Medical Center, San Francisco - Internal Medicine
• Residency: University of California, San Francisco - Diagnostic Radiology
• Fellowship: University of California, San Francisco - Neuroradiology
• Doctor of Philosophy: University of Louisville, Kentucky
• American Board of Radiology, Certificate in Diagnostic Radiology
• California Certificate

Education

Neuroradiology Fellowship, 2013 - Radiology and Biomedical Imaging, University of California, San Francisco
Residency, 2012 - Radiology and Biomedical Imaging, University of California, San Francisco
Medicine Internship, 2008 - Medicine, California Pacific Medical Center
MD/PhD, 2007 - School of Medicine, University of Louisville
BS, 2000 - Biology, Stanford University

Honors and Awards

Margulis Society Outstanding Resident Research Award, University of California, San Francisco, 2012
Chief Resident, University of Califonria, San Francisco, 2011-2012
Institutional National Research Service Award, NIH, 2010
Margulis Society Grant Awardee, University of California, San Francisco, 2010
Alpha Omega Alpha Honor Society, 2006
Speaker’s Award, International Society of Neurotransplantation and Repair, 2002

Publications

Jenkins NW, Iriondo C, Shah V, Bahroos E, Ravanfar V, Regan M, Seo Y, Dillon WP, Majumdar S, Talbott JF. Quantitative [18F]-Naf-PET-MRI Analysis for the Evaluation of Dynamic Bone Turnover in a Patient with Facetogenic Low Back Pain. J Vis Exp. 2019 Aug 08; (150).
Burke JF, Yue JK, Ngwenya LB, Winkler EA, Talbott JF, Pan JZ, Ferguson AR, Beattie MS, Bresnahan JC, Haefeli J, Whetstone WD, Suen CG, Huang MC, Manley GT, Tarapore PE, Dhall SS. In Reply: Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury. Neurosurgery. 2019 Aug 01; 85(2):E401-E402.
Talbott JF, Hess CP. Is Dual-Energy CT Ready for Primetime in Traumatic Brain Injury? Radiology. 2019 Jul 30; 191528.
Bucknor MD, Villanueva-Meyer JE, Kumar V, Talbott JF, Wall SD, Glastonbury CM, Dillon WP, Arenson RL, Wilson MW, Hess CP. Diversity and Inclusion Efforts in University of California, San Francisco Radiology: Reflections on 3 Years of Pipeline, Selection, and Education Initiatives. J Am Coll Radiol. 2019 Jul 09.
Chazen JL, Ebani EJ, Virk M, Talbott JF, Shah V. CT-Guided Block and Radiofrequency Ablation of the C2 Dorsal Root Ganglion for Cervicogenic Headache. AJNR Am J Neuroradiol. 2019 Jul 04.
Li Z, Chen YA, Chow D, Talbott J, Glastonbury C, Shah V. Practical applications of CISS MRI in spine imaging. Eur J Radiol Open. 2019; 6:231-242.
Kallianos KG, Webb EM, Hess CP, Talbott J, Bucknor MD. Use of the Implicit Association Test to Improve Diversity in Radiology. J Am Coll Radiol. 2019 Apr 11.
McCoy DB, Dupont SM, Gros C, Cohen-Adad J, Huie RJ, Ferguson A, Duong-Fernandez X, Thomas LH, Singh V, Narvid J, Pascual L, Kyritsis N, Beattie MS, Bresnahan JC, Dhall S, Whetstone W, Talbott JF. Convolutional Neural Network-Based Automated Segmentation of the Spinal Cord and Contusion Injury: Deep Learning Biomarker Correlates of Motor Impairment in Acute Spinal Cord Injury. AJNR Am J Neuroradiol. 2019 Apr; 40(4):737-744.
Eden D, Gros C, Badji A, Dupont SM, De Leener B, Maranzano J, Zhuoquiong R, Liu Y, Granberg T, Ouellette R, Stawiarz L, Hillert J, Talbott J, Bannier E, Kerbrat A, Edan G, Labauge P, Callot V, Pelletier J, Audoin B, Rasoanandrianina H, Brisset JC, Valsasina P, Rocca MA, Filippi M, Bakshi R, Tauhid S, Prados F, Yiannakas M, Kearney H, Ciccarelli O, Smith SA, Andrada Treaba C, Mainero C, Lefeuvre J, Reich DS, Nair G, Shepherd TM, Charlson E, Tachibana Y, Hori M, Kamiya K, Chougar L, Narayanan S, Cohen-Adad J. Spatial distribution of multiple sclerosis lesions in the cervical spinal cord. Brain. 2019 Mar 01; 142(3):633-646.
Lau D, Dalle Ore CL, Tarapore PE, Huang M, Manley G, Singh V, Mummaneni PV, Beattie M, Bresnahan J, Ferguson AR, Talbott JF, Whetstone W, Dhall SS. Value of aggressive surgical and intensive care unit in elderly patients with traumatic spinal cord injury. Neurosurg Focus. 2019 Mar 01; 46(3):E3.
Burke JF, Yue JK, Ngwenya LB, Winkler EA, Talbott JF, Pan JZ, Ferguson AR, Beattie MS, Bresnahan JC, Haefeli J, Whetstone WD, Suen CG, Huang MC, Manley GT, Tarapore PE, Dhall SS. Ultra-Early (<12 Hours) Surgery Correlates With Higher Rate of American Spinal Injury Association Impairment Scale Conversion After Cervical Spinal Cord Injury. Neurosurgery. 2018 Nov 28.
Talbott JF, Huie JR, Ferguson AR, Bresnahan JC, Beattie MS, Dhall SS. MR Imaging for Assessing Injury Severity and Prognosis in Acute Traumatic Spinal Cord Injury. Radiol Clin North Am. 2019 Mar; 57(2):319-339.
Gros C, De Leener B, Badji A, Maranzano J, Eden D, Dupont SM, Talbott J, Zhuoquiong R, Liu Y, Granberg T, Ouellette R, Tachibana Y, Hori M, Kamiya K, Chougar L, Stawiarz L, Hillert J, Bannier E, Kerbrat A, Edan G, Labauge P, Callot V, Pelletier J, Audoin B, Rasoanandrianina H, Brisset JC, Valsasina P, Rocca MA, Filippi M, Bakshi R, Tauhid S, Prados F, Yiannakas M, Kearney H, Ciccarelli O, Smith S, Treaba CA, Mainero C, Lefeuvre J, Reich DS, Nair G, Auclair V, McLaren DG, Martin AR, Fehlings MG, Vahdat S, Khatibi A, Doyon J, Shepherd T, Charlson E, Narayanan S, Cohen-Adad J. Automatic segmentation of the spinal cord and intramedullary multiple sclerosis lesions with convolutional neural networks. Neuroimage. 2019 01 01; 184:901-915.
Talbott JF, Shah VN, Uzelac A, Narvid J, Dumont RA, Chin CT, Wilson DM. Imaging-Based Approach to Extradural Infections of the Spine. Semin Ultrasound CT MR. 2018 12; 39(6):570-586.
Farhadi HF, Minnema AJ, Talbott JF, Aarabi B. Letter to the Editor: What Has Been Learned from Magnetic Resonance Imaging Examination of the Injured Human Spinal Cord: A Canadian Perspective. J Neurotrauma. 2018 Sep 05.
Narvid J, Callen A, Talbott J, Uzelac A, Dupont SM, Chow F, Price RW, Rehani B. Brain MRI Features of CSF Human Immunodeficiency Virus Escape. J Neuroimaging. 2018 Nov; 28(6):601-607.
Dhall SS, Haefeli J, Talbott JF, Ferguson AR, Readdy WJ, Bresnahan JC, Beattie MS, Pan JZ, Manley GT, Whetstone WD. Motor Evoked Potentials Correlate With Magnetic Resonance Imaging and Early Recovery After Acute Spinal Cord Injury. Neurosurgery. 2018 Jun 01; 82(6):870-876.
Graterol J, Beylin M, Whetstone WD, Matzoll A, Burke R, Talbott J, Rodriguez RM. Low Yield of Paired Head and Cervical Spine Computed Tomography in Blunt Trauma Evaluation. J Emerg Med. 2018 06; 54(6):749-756.
Talbott JF, Cooke DL, Mabray MC, Larson PS, Amans MR, Hetts SW, Wilson MW, Moore T, Salegio EA. Accuracy of image-guided percutaneous injection into a phantom spinal cord utilizing flat panel detector CT with MR fusion and integrated navigational software. J Neurointerv Surg. 2018 Dec; 10(12):e37.
Dumont RA, Keen NN, Bloomer CW, Schwartz BS, Talbott J, Clark AJ, Wilson DM, Chin CT. Clinical Utility of Diffusion-Weighted Imaging in Spinal Infections. Clin Neuroradiol. 2018 Mar 26.
Devulapalli KK, Talbott JF, Narvid J, Gean A, Rehani B, Manley G, Uzelac A, Yuh E, Huang MC. Utility of Repeat Head CT in Patients with Blunt Traumatic Brain Injury Presenting with Small Isolated Falcine or Tentorial Subdural Hematomas. AJNR Am J Neuroradiol. 2018 04; 39(4):654-657.
DiGiorgio AM, Tsolinas R, Alazzeh M, Haefeli J, Talbott JF, Ferguson AR, Bresnahan JC, Beattie MS, Manley GT, Whetstone WD, Mummaneni PV, Dhall SS. Safety and effectiveness of early chemical deep venous thrombosis prophylaxis after spinal cord injury: pilot prospective data. Neurosurg Focus. 2017 Nov; 43(5):E21.
Jenkins NW, Talbott JF, Shah V, Pandit P, Seo Y, Dillon WP, Majumdar S. [18F]-Sodium Fluoride PET MR-Based Localization and Quantification of Bone Turnover as a Biomarker for Facet Joint-Induced Disability. AJNR Am J Neuroradiol. 2017 Oct; 38(10):2028-2031.
Yue JK, Robinson CK, Burke JF, Winkler EA, Deng H, Cnossen MC, Lingsma HF, Ferguson AR, McAllister TW, Rosand J, Burchard EG, Sorani MD, Sharma S, Nielson JL, Satris GG, Talbott JF, Tarapore PE, Korley FK, Wang KKW, Yuh EL, Mukherjee P, Diaz-Arrastia R, Valadka AB, Okonkwo DO, Manley GT. Apolipoprotein E epsilon 4 (APOE-e4) genotype is associated with decreased 6-month verbal memory performance after mild traumatic brain injury. Brain Behav. 2017 09; 7(9):e00791.
Busby LP, Herron SM, Talbott JF, Uzelac A, Rehani B. Encephalomyelitis After Varicella Zoster Reactivation in an Immunocompromised Patient. Neurohospitalist. 2018 Apr; 8(2):NP1-NP2.
Haefeli J, Mabray MC, Whetstone WD, Dhall SS, Pan JZ, Upadhyayula P, Manley GT, Bresnahan JC, Beattie MS, Ferguson AR, Talbott JF. Multivariate Analysis of MRI Biomarkers for Predicting Neurologic Impairment in Cervical Spinal Cord Injury. AJNR Am J Neuroradiol. 2017 Mar; 38(3):648-655.
McCoy DB, Talbott JF, Wilson M, Mamlouk MD, Cohen-Adad J, Wilson M, Narvid J. MRI Atlas-Based Measurement of Spinal Cord Injury Predicts Outcome in Acute Flaccid Myelitis. AJNR Am J Neuroradiol. 2017 Feb; 38(2):410-417.
Readdy WJ, Saigal R, Whetstone WD, Mefford AN, Ferguson AR, Talbott JF, Inoue T, Bresnahan JC, Beattie MS, Pan J, Manley GT, Dhall SS. Failure of Mean Arterial Pressure Goals to Improve Outcomes Following Penetrating Spinal Cord Injury. Neurosurgery. 2016 Nov; 79(5):708-714.
Mutch CA, Talbott JF, Gean A. Imaging Evaluation of Acute Traumatic Brain Injury. Neurosurg Clin N Am. 2016; 4(27):409-39.
Catapano JS, John Hawryluk GW, Whetstone W, Saigal R, Ferguson A, Talbott J, Bresnahan J, Dhall S, Pan J, Beattie M, Manley G. Higher Mean Arterial Pressure Values Correlate with Neurologic Improvement in Patients with Initially Complete Spinal Cord Injuries. World Neurosurg. 2016 Dec; 96:72-79.
Park I, Nelson SJ, Talbott JF. In Vivo Monitoring of Rat Spinal Cord Metabolism Using Hyperpolarized Carbon-13 MR Spectroscopic Imaging. AJNR Am J Neuroradiol. 2016 12; 37(12):2407-2409.
Burke JF, Yue JK, Ngwenya LB, Winkler EA, Talbott J, Pan J, Ferguson A, Beattie M, Bresnahan J, Haefeli J, Whetstone W, Suen C, Huang MC, Manley GT, Tarapore PE, Dhall SS. 182 Ultra-Early (<12 Hours) Decompression Improves Recovery After Spinal Cord Injury Compared to Early (12-24 Hours) Decompression. Neurosurgery. 2016 Aug; 63 Suppl 1:172.
Robbins NM, Shah V, Benedetti N, Talbott JF, Chin CT, Douglas VC. Magnetic resonance neurography in the diagnosis of neuropathies of the lumbosacral plexus: a pictorial review. Clin Imaging. 2016 Nov - Dec; 40(6):1118-1130.
Pandit P, Talbott JF, Pedoia V, Dillon W, Majumdar S. T1? and T2 -based characterization of regional variations in intervertebral discs to detect early degenerative changes. J Orthop Res. 2016 08; 34(8):1373-81.
Talbott JF, Narvid J, Chazen JL, Chin CT, Shah V. An Imaging-Based Approach to Spinal Cord Infection. Semin Ultrasound CT MR. 2016 Oct; 37(5):411-30.
Chazen JL, Talbott J, Singh JR. Optimal Noninvasive Imaging for Suspected Zygapophyseal (Facet)-Mediated Low Back Pain. PM R. 2016 06; 8(6):586-92.
Readdy WJ, Saigal R, Whetstone WD, Mefford A, Ferguson AR, Talbott JF, Inoue T, Bresnahan JC, Beattie MS, Pan J, Manley GT, Dhall SS. Failure of Mean Arterial Pressure Goals to Improve Outcomes Following Penetrating Spinal Cord Injury. Neurosurgery. 2016 May 03.
Mabray MC, Brus-Ramer M, Behr SC, Pampaloni MH, Majumdar S, Dillon WP, Talbott JF. (18)F-Sodium Fluoride PET-CT Hybrid Imaging of the Lumbar Facet Joints: Tracer Uptake and Degree of Correlation to CT-graded Arthropathy. World J Nucl Med. 2016 May-Aug; 15(2):85-90.
Phillips D, Dhall SS, Uzelac A, Talbott JF. Gunshot wound causing anterior spinal cord infarction due to injury to the artery of Adamkiewicz. Spine J. 2016 Sep; 16(9):e603-4.
Talbott JF, Nout-Lomas YS, Wendland MF, Mukherjee P, Huie JR, Hess CP, Mabray MC, Bresnahan JC, Beattie MS. Diffusion-Weighted Magnetic Resonance Imaging Characterization of White Matter Injury Produced by Axon-Sparing Demyelination and Severe Contusion Spinal Cord Injury in Rats. J Neurotrauma. 2016 05 15; 33(10):929-42.
Mabray MC, Talbott JF, Whetstone WD, Dhall SS, Phillips DB, Pan JZ, Manley GT, Bresnahan JC, Beattie MS, Haefeli J, Ferguson AR. Multidimensional Analysis of Magnetic Resonance Imaging Predicts Early Impairment in Thoracic and Thoracolumbar Spinal Cord Injury. J Neurotrauma. 2016 05 15; 33(10):954-62.
Simon NG, Talbott J, Chin CT, Kliot M. Peripheral nerve imaging. Handb Clin Neurol. 2016; 136:811-26.
Kozak B, Talbott J, Uzelac A, Rehani B. Rosai-Dorfman Disease Isolated to the Thoracic Epidural Spine. J Radiol Case Rep. 2015 Nov; 9(11):6-16.
Talbott JF, Whetstone WD, Readdy WJ, Ferguson AR, Bresnahan JC, Saigal R, Hawryluk GW, Beattie MS, Mabray MC, Pan JZ, Manley GT, Dhall SS. The Brain and Spinal Injury Center score: a novel, simple, and reproducible method for assessing the severity of acute cervical spinal cord injury with axial T2-weighted MRI findings. J Neurosurg Spine. 2015; 4(23):495-504.
Narvid J, Rehani B, Talbott JF. Diagnostic Performance of Brain MRI in Immune Reconstitution Inflammatory Syndrome. J Neuroimaging. 2016 05; 26(3):303-8.
Hawryluk G, Whetstone W, Saigal R, Ferguson A, Talbott J, Bresnahan J, Dhall S, Pan J, Beattie M, Manley G. Mean Arterial Blood Pressure Correlates with Neurological Recovery after Human Spinal Cord Injury: Analysis of High Frequency Physiologic Data. J Neurotrauma. 2015 Dec 15; 32(24):1958-67.
Narvid J, Talbott JF, Glastonbury CM. The caverno-apical triangle: anatomic-pathological considerations and pictorial review. Clin Imaging. 2016 Jan-Feb; 40(1):23-32.
Readdy WJ, Whetstone WD, Ferguson AR, Talbott JF, Inoue T, Saigal R, Bresnahan JC, Beattie MS, Pan JZ, Manley GT, Dhall SS. Complications and outcomes of vasopressor usage in acute traumatic central cord syndrome. J Neurosurg Spine. 2015 Nov; 23(5):574-580.
Talbott JF, Whetstone WD, Readdy WJ, Ferguson AR, Bresnahan JC, Saigal R, Hawryluk GW, Beattie MS, Mabray MC, Pan JZ, Manley GT, Dhall SS. The Brain and Spinal Injury Center score: a novel, simple, and reproducible method for assessing the severity of acute cervical spinal cord injury with axial T2-weighted MRI findings. J Neurosurg Spine. 2015 Oct; 23(4):495-504.
Mabray MC, Datta S, Lillaney PV, Moore T, Gehrisch S, Talbott JF, Levitt MR, Ghodke BV, Larson PS, Cooke DL. Accuracy of flat panel detector CT with integrated navigational software with and without MR fusion for single-pass needle placement. J Neurointerv Surg. 2016 Jul; 8(7):731-5.
Mabray MC, Uzelac A, Talbott JF, Lin SC, Gean AD. Ex-PRESS glaucoma filter: an MRI compatible metallic orbital foreign body imaged at 1.5 and 3T. Clin Radiol. 2015 May; 70(5):e28-34.
Talbott JF, Gean A, Yuh EL, Stiver SI. Reply: To PMID 24948502. AJNR Am J Neuroradiol. 2015 Mar; 36(3):E25.
Baud MO, Uzelac A, Jay CA, Talbott JF. CNS siderosis and orthostatic headache as a delayed complication of spinal surgery. Neurology. 2014 Nov 25; 83(22):2097-8.
Irvine KA, Ferguson AR, Mitchell KD, Beattie SB, Lin A, Stuck ED, Huie JR, Nielson JL, Talbott JF, Inoue T, Beattie MS, Bresnahan JC. The Irvine, Beatties, and Bresnahan (IBB) Forelimb Recovery Scale: An Assessment of Reliability and Validity. Front Neurol. 2014; 5:116.
Talbott JF, Gean A, Yuh EL, Stiver SI. Calvarial fracture patterns on CT imaging predict risk of a delayed epidural hematoma following decompressive craniectomy for traumatic brain injury. AJNR Am J Neuroradiol. 2014 Oct; 35(10):1930-5.
Chazen JL, Talbott JF, Lantos JE, Dillon WP. MR myelography for identification of spinal CSF leak in spontaneous intracranial hypotension. AJNR Am J Neuroradiol. 2014 Oct; 35(10):2007-12.
Chow H, Jung A, Talbott J, Lin AM, Daud AI, Coakley FV. Tumor fistulization associated with targeted therapy: computed tomographic findings and clinical consequences. J Comput Assist Tomogr. 2011 Jan-Feb; 35(1):86-90.
Talbott JF, Cao Q, Bertram J, Nkansah M, Benton RL, Lavik E, Whittemore SR. CNTF promotes the survival and differentiation of adult spinal cord-derived oligodendrocyte precursor cells in vitro but fails to promote remyelination in vivo. Exp Neurol. 2007 Mar; 204(1):485-9.
Talbott JF, Cao Q, Enzmann GU, Benton RL, Achim V, Cheng XX, Mills MD, Rao MS, Whittemore SR. Schwann cell-like differentiation by adult oligodendrocyte precursor cells following engraftment into the demyelinated spinal cord is BMP-dependent. Glia. 2006 Aug 15; 54(3):147-59.
Enzmann GU, Benton RL, Talbott JF, Cao Q, Whittemore SR. Functional considerations of stem cell transplantation therapy for spinal cord repair. J Neurotrauma. 2006 Mar-Apr; 23(3-4):479-95.
Talbott JF, Loy DN, Liu Y, Qiu MS, Bunge MB, Rao MS, Whittemore SR. Endogenous Nkx2.2+/Olig2+ oligodendrocyte precursor cells fail to remyelinate the demyelinated adult rat spinal cord in the absence of astrocytes. Exp Neurol. 2005 Mar; 192(1):11-24.
Loy DN, Sroufe AE, Pelt JL, Burke DA, Cao QL, Talbott JF, Whittemore SR. Serum biomarkers for experimental acute spinal cord injury: rapid elevation of neuron-specific enolase and S-100beta. Neurosurgery. 2005 Feb; 56(2):391-7; discussion 391-7.
Krouse ME, Talbott JF, Lee MM, Joo NS, Wine JJ. Acid and base secretion in the Calu-3 model of human serous cells. Am J Physiol Lung Cell Mol Physiol. 2004 Dec; 287(6):L1274-83.
Loy DN, Talbott JF, Onifer SM, Mills MD, Burke DA, Dennison JB, Fajardo LC, Magnuson DS, Whittemore SR. Both dorsal and ventral spinal cord pathways contribute to overground locomotion in the adult rat. Exp Neurol. 2002 Oct; 177(2):575-80.
Talbott JF, Gorti GK, Koch RJ. Midfacial osteomyelitis in a chronic cocaine abuser: a case report. Ear Nose Throat J. 2001 Oct; 80(10):738-40, 742-3.