Eugene Ozhinsky, PhD

Associate Adjunct Professor
Associate Adjunct Professor
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Biography

Eugene Ozhinsky, PhD is an Associate Professor in the Department of Radiology and Biomedical Imaging, University of California San Francisco. His main research interests are in the areas of machine learning for musculoskeletal imaging and MR-guided focused ultrasound therapy.

He is working at the VA Advanced Imaging Research Center (VAARC, part of San Francisco Veterans Affairs Health Care System) on development and implementation of machine learning techniques for automated image processing, analysis, and prescription of musculoskeletal X-ray, MRI, PET, and CT images. The goal of this work is to improve care for the VA patient population by enabling precise diagnostics, prediction of disease progression, as well as response to therapy.

As a Technical Director for Focused Ultrasound at the Department of Radiology and Biomedical Imaging, Dr. Ozhinsky is supporting clinical focused ultrasound treatments of patients with neurological and oncological conditions. His current research focuses on safely and effectively opening of blood-brain barrier to enable delivery of therapeutics to the brain.

Dr. Ozhinsky has obtained his PhD in the UC Berkeley/UCSF Joint Graduate Program in Bioengineering. His dissertation work was on automated acquisition of brain magnetic resonance spectroscopy data.

Education

Ph.D., 2012 - Graduate Division (Bioengineering), University of California, San Francisco

Honors and Awards

Outstanding Poster Presentation Award, 13th Annual Imaging Research Symposium, UCSF, 2016
Magna Cum Laude Merit Award, International Society for Magnetic Resonance in Medicine, 2014
Surbeck Scholar Award (1st place), INDNJC Foundation, 2011
Graduate Dean's Health Science Fellowship, UCSF, 2006

Publications

Kim K, Gallus M, Xiao T, Parchure AS, Shah BR, Okada H, Diederich C, Ozhinsky E, Narsinh K. Monitoring Blood-Brain Barrier Opening in Rats with a Preclinical Focused Ultrasound System. J Vis Exp. 2024 Sep 13; (211).
Kim K, Gupta P, Narsinh K, Diederich CJ, Ozhinsky E. Volumetric hyperthermia delivery using the ExAblate Body MR-guided focused ultrasound system. Int J Hyperthermia. 2024; 41(1):2349080.
Ozhinsky E, Liu F, Pedoia V, Majumdar S. Machine learning-based automated scan prescription of lumbar spine MRI acquisitions. Magn Reson Imaging. 2024 Jul; 110:29-34.
Kim K, Narsinh K, Ozhinsky E. Technical advances in motion-robust MR thermometry. Magn Reson Med. 2024 Jul; 92(1):15-27.
Zhu Y, Deng K, Zhou J, Lai C, Ma Z, Zhang H, Pan J, Shen L, Bucknor MD, Ozhinsky E, Kim S, Chen G, Ye SH, Zhang Y, Liu D, Gao C, Xu Y, Wang H, Wagner WR. Shape-recovery of implanted shape-memory devices remotely triggered via image-guided ultrasound heating. Nat Commun. 2024 Feb 06; 15(1):1123.
Mattay RR, Kim K, Shah L, Shah B, Sugrue L, Safoora F, Ozhinsky E, Narsinh KH. MR Thermometry during Transcranial MR Imaging-Guided Focused Ultrasound Procedures: A Review. AJNR Am J Neuroradiol. 2023 12 29; 45(1):1-8.
Ellison J, Kim K, Li Y, Mu X, Glenn O, Ozhinsky E, Peyvandi S, Xu D. Estimate of fetal brain temperature using proton resonance frequency thermometry during 3 Tesla fetal magnetic resonance imaging. Quant Imaging Med Surg. 2023 Dec 01; 13(12):7987-7995.
Düx DM, Baal JD, Bitton R, Chen J, Brunsing RL, Sheth VR, Rosenberg J, Kim K, Ozhinsky E, Avedian R, Ganjoo K, Bucknor M, Dobrotwir A, Ghanouni P. MR-guided focused ultrasound therapy of extra-abdominal desmoid tumors: a multicenter retrospective study of 105 patients. Eur Radiol. 2024 Feb; 34(2):1137-1145.
Sollmann N, Fields AJ, O'Neill C, Nardo L, Majumdar S, Chin CT, Tosun D, Han M, Vu AT, Ozhinsky E, Shah LM, Harris RE, Lobo R, Anderst W, Herzog R, Psioda MA, Standaert CJ, Price RT, Lotz JC, Link TM, Krug R. Magnetic Resonance Imaging of the Lumbar Spine: Recommendations for Acquisition and Image Evaluation from the BACPAC Spine Imaging Working Group. Pain Med. 2023 08 04; 24(Suppl 1):S81-S94.
Kim K, Diederich C, Narsinh K, Ozhinsky E. Motion-robust, multi-slice, real-time MR thermometry for MR-guided thermal therapy in abdominal organs. Int J Hyperthermia. 2023; 40(1):2151649.
Kim K, Jones P, Diederich C, Ozhinsky E. Technical note: Low-cost MR-compatible pneumatic respiratory organ motion simulator for the development of MR-guided thermal therapy. Med Phys. 2022 Jul; 49(7):4365-4371.
Calivà F, Namiri NK, Dubreuil M, Pedoia V, Ozhinsky E, Majumdar S. Studying osteoarthritis with artificial intelligence applied to magnetic resonance imaging. Nat Rev Rheumatol. 2022 02; 18(2):112-121.
Zhang W, Trivedi H, Adams M, Losey AD, Diederich CJ, Ozhinsky E, Rieke V, Bucknor MD. Anatomic thermochromic tissue-mimicking phantom of the lumbar spine for pre-clinical evaluation of MR-guided focused ultrasound (MRgFUS) ablation of the facet joint. Int J Hyperthermia. 2021; 38(1):130-135.
Kim K, Zubair M, Adams M, Diederich CJ, Ozhinsky E. Sonication strategies toward volumetric ultrasound hyperthermia treatment using the ExAblate body MRgFUS system. Int J Hyperthermia. 2021; 38(1):1590-1600.
Tibrewala R, Ozhinsky E, Shah R, Flament I, Crossley K, Srinivasan R, Souza R, Link TM, Pedoia V, Majumdar S. Computer-Aided Detection AI Reduces Interreader Variability in Grading Hip Abnormalities With MRI. J Magn Reson Imaging. 2020 10; 52(4):1163-1172.
Krogue JD, Cheng KV, Hwang KM, Toogood P, Meinberg EG, Geiger EJ, Zaid M, McGill KC, Patel R, Sohn JH, Wright A, Darger BF, Padrez KA, Ozhinsky E, Majumdar S, Pedoia V. Automatic Hip Fracture Identification and Functional Subclassification with Deep Learning. Radiol Artif Intell. 2020 Mar; 2(2):e190023.
von Schacky CE, Sohn JH, Liu F, Ozhinsky E, Jungmann PM, Nardo L, Posadzy M, Foreman SC, Nevitt MC, Link TM, Pedoia V. Development and Validation of a Multitask Deep Learning Model for Severity Grading of Hip Osteoarthritis Features on Radiographs. Radiology. 2020 04; 295(1):136-145.
Jordan CD, Thorne BRH, Wadhwa A, Losey AD, Ozhinsky E, Kondapavulur S, Fratello V, Moore T, Stillson C, Yee C, Watkins RD, Scott GC, Martin AJ, Zhang X, Wilson MW, Hetts SW. Wireless Resonant Circuits Printed Using Aerosol Jet Deposition for MRI Catheter Tracking. IEEE Trans Biomed Eng. 2020 03; 67(3):876-882.
Bucknor MD, Beroukhim G, Rieke V, Ozhinsky E, Lobach I. The impact of technical parameters on ablation volume during MR-guided focused ultrasound of desmoid tumors. Int J Hyperthermia. 2019; 36(1):473-476.
Morochnik S, Ozhinsky E, Rieke V, Bucknor MD. T2 mapping as a predictor of nonperfused volume in MRgFUS treatment of desmoid tumors. Int J Hyperthermia. 2019; 36(1):1272-1277.
Ozhinsky E, Salgaonkar VA, Diederich CJ, Rieke V. MR thermometry-guided ultrasound hyperthermia of user-defined regions using the ExAblate prostate ablation array. J Ther Ultrasound. 2018; 6:7.
Bucknor MD, Ozhinsky E, Shah R, Krug R, Rieke V. Effect of Sonication Duration and Power on Ablation Depth During MR-Guided Focused Ultrasound of Bone. J Magn Reson Imaging. 2017 11; 46(5):1418-1422.
Ozhinsky E, Han M, Bucknor M, Krug R, Rieke V. T2-based temperature monitoring in bone marrow for MR-guided focused ultrasound. J Ther Ultrasound. 2016; 4:26.
Han M, Rieke V, Scott SJ, Ozhinsky E, Salgaonkar VA, Jones PD, Larson PE, Diederich CJ, Krug R. Quantifying temperature-dependent T1 changes in cortical bone using ultrashort echo-time MRI. Magn Reson Med. 2015 Dec; 74(6):1548-55.
Ozhinsky E, Kohi MP, Ghanouni P, Rieke V. T2-based temperature monitoring in abdominal fat during MR-guided focused ultrasound treatment of patients with uterine fibroids. J Ther Ultrasound. 2015; 3:15.
Li Y, Larson P, Chen AP, Lupo JM, Ozhinsky E, Kelley D, Chang SM, Nelson SJ. Short-echo three-dimensional H-1 MR spectroscopic imaging of patients with glioma at 7 Tesla for characterization of differences in metabolite levels. J Magn Reson Imaging. 2015 May; 41(5):1332-41.
Salgaonkar VA, Prakash P, Rieke V, Ozhinsky E, Plata J, Kurhanewicz J, Hsu IC, Diederich CJ. Model-based feasibility assessment and evaluation of prostate hyperthermia with a commercial MR-guided endorectal HIFU ablation array. Med Phys. 2014 Mar; 41(3):033301.
Nelson SJ, Ozhinsky E, Li Y, Park Iw, Crane J. Strategies for rapid in vivo 1H and hyperpolarized 13C MR spectroscopic imaging. J Magn Reson. 2013 Apr; 229:187-97.
Ozhinsky E, Vigneron DB, Chang SM, Nelson SJ. Automated prescription of oblique brain 3D magnetic resonance spectroscopic imaging. Magn Reson Med. 2013 Apr; 69(4):920-30.
Goldenstein J, Schooler J, Crane JC, Ozhinsky E, Pialat JB, Carballido-Gamio J, Majumdar S. Prospective image registration for automated scan prescription of follow-up knee images in quantitative studies. Magn Reson Imaging. 2011 Jun; 29(5):693-700.
Ozhinsky E, Vigneron DB, Nelson SJ. Improved spatial coverage for brain 3D PRESS MRSI by automatic placement of outer-volume suppression saturation bands. J Magn Reson Imaging. 2011 Apr; 33(4):792-802.
Bauer JS, Krause SJ, Ross CJ, Krug R, Carballido-Gamio J, Ozhinsky E, Majumdar S, Link TM. Volumetric cartilage measurements of porcine knee at 1.5-T and 3.0-T MR imaging: evaluation of precision and accuracy. Radiology. 2006 Nov; 241(2):399-406.
Lee KY, Dunn TC, Steinbach LS, Ozhinsky E, Ries MD, Majumdar S. Computer-aided quantification of focal cartilage lesions of osteoarthritic knee using MRI. Magn Reson Imaging. 2004 Oct; 22(8):1105-15.
Pothuaud L, Van Rietbergen B, Charlot C, Ozhinsky E, Majumdar S. A new computational efficient approach for trabecular bone analysis using beam models generated with skeletonized graph technique. Comput Methods Biomech Biomed Engin. 2004 Aug; 7(4):205-13.
Patel VV, Hall K, Ries M, Lotz J, Ozhinsky E, Lindsey C, Lu Y, Majumdar S. A three-dimensional MRI analysis of knee kinematics. J Orthop Res. 2004 Mar; 22(2):283-92.
Patel VV, Hall K, Ries M, Lindsey C, Ozhinsky E, Lu Y, Majumdar S. Magnetic resonance imaging of patellofemoral kinematics with weight-bearing. J Bone Joint Surg Am. 2003 Dec; 85(12):2419-24.