Duan Xu, PhD

Professor
ASSOC PROF IN RES-HCOMP

Biography

Duan Xu, PhD, is a Professor in Residence and leads the Imaging Research for Neurodevelopment Laboratory at the University of California, San Francisco Parnassus and Mission Bay. Dr. Xu obtained his BA in Integrated Science and BS in Biomedical Engineering from Northwestern University in Evanston, Illinois in 1999, followed by his PhD in Bioengineering from the University of California, San Francisco and Berkeley in 2005. He is a member of the Advanced Imaging Technologies Resource Group and a member of the Pediatric and Fetal Research Interest Group specializing in the baby brain.

Dr. Xu’s research focuses on investigating new MRI techniques using primary applications in pediatric neuroradiology. Another research focus is the development of new techniques for ultrahigh field MR scanners involving small animal images, in vivo and ex vivo. Dr. Xu is developing high resolution MR anatomic, diffusion, and spectroscopic techniques with unprecedented resolution in collaboration with various colleagues in Neurodevelopment Biology, Neurology, Pediatrics, Neonatology, and Physiology.

Dr. Xu is an active member of the International Society of Magnetic Resonance in Medicine, the American Society of Neuroradiology, the Society of Molecular Imaging, and the Medical Image Computing and Computer Assisted Intervention Society.

Expertise:
MRI, diffusion, spectroscopy, pediatrics, brain, neurodevelopment

Education

Postdoctoral Studies, 2008 - Graduate Division, University of California, San Francisco
Ph.D., 2005 - Bioengineering, University of California, San Francisco and Berkeley
BS and BA, 1999 - Biomedical Engineering and Integrated Science, Northwestern University

Honors and Awards

Distinguished Investigator, Academy of Radiology Research, 2016
MRM Distinguished Reviewer, Magnetic Resonance in Medicine Journal, 2011
Surbeck Scholarship Award, University of California, San Francisco, 2006
ARCS Scholarship, ARCS Foundation, 2003
Graduate Research Award, University of California, San Francisco, 2003
NSF Graduate Fellowship Honorable Mention, National Science Foundation, 2002

Publications

Autry AW, Gordon JW, Chen HY, LaFontaine M, Bok R, Van Criekinge M, Slater JB, Carvajal L, Villanueva-Meyer JE, Chang SM, Clarke JL, Lupo JM, Xu D, Larson PEZ, Vigneron DB, Li Y. Characterization of serial hyperpolarized 13C metabolic imaging in patients with glioma. Neuroimage Clin. 2020 Jun 24; 27:102323.
Mikrogeorgiou A, Chen Y, Lee BS, Bok R, Sheldon RA, Barkovich AJ, Xu D, Ferriero DM. A Metabolomics Study of Hypoxia Ischemia during Mouse Brain Development Using Hyperpolarized 13C. Dev Neurosci. 2020 Jun 22; 1-10.
Chen HY, Autry AW, Brender JR, Kishimoto S, Krishna MC, Vareth M, Bok RA, Reed GD, Carvajal L, Gordon JW, van Criekinge M, Korenchan DE, Chen AP, Xu D, Li Y, Chang SM, Kurhanewicz J, Larson PEZ, Vigneron DB. Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized 13 C MRSI. Magn Reson Med. 2020 Jun 05.
Crane JC, Gordon JW, Chen HY, Autry AW, Li Y, Olson MP, Kurhanewicz J, Vigneron DB, Larson PEZ, Xu D. Hyperpolarized 13 C MRI data acquisition and analysis in prostate and brain at University of California, San Francisco. NMR Biomed. 2020 Mar 19; e4280.
Lu F, Fan S, Romo AR, Xu D, Ferriero DM, Jiang X. Serum 24S-hydroxycholesterol predicts long-term brain structural and functional outcomes after hypoxia-ischemia in neonatal mice. J Cereb Blood Flow Metab. 2020 Mar 13; 271678X20911910.
Adam Autry, Jeremy Gordon, Hsin-Yu Chen, Marisa Lafontaine, Javier Villanueva-Meyer, Susan Chang, Duan Xu, Peder Larson, Daniel Vigneron, Yan Li. CBMT-26. SERIAL CHARACTERIZATION OF HYPERPOLARIZED [1-13C]PYRUVATE METABOLISM IN PATIENTS WITH GLIOMA AND THE INFLUENCE OF BEVACIZUMAB. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi38-vi39.
Jing Liu, Angela Jakary, Marisa Lafontaine, Yan Wang, Duan Xu, David Saloner, Nicholas Butowski, Christopher Hess, Javier Villanueva-Meyer, Susan Chang, Janine Lupo. NIMG-45. 3D SINGLE-SCAN FOR MULTI-CONTRAST-WEIGHTED MRI FOR LESION DETECTION IN PATIENTS WITH GLIOMAS. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi171-vi171.
Javier Villanueva-Meyer, Adam Autry, Jeremy Gordon, Hsin-Yu Chen, Marisa Lafontaine, Susan Chang, Duan Xu, Peder Larson, Daniel Vigneron, Yan Li. NIMG-57. SERIAL HYPERPOLARIZED 13C PYRUVATE AND 1H METABOLIC IMAGING IN RECURRENT HIGH-GRADE GLIOMA. Neuro-Oncology. 2019 Nov 11; 21(Supplement_6):vi174-vi174.
Wang H, Huang B, Wang W, Li J, Chen Y, Flynn T, Zhao M, Zhou Z, Lin X, Zhang Y, Xu M, Li K, Tian K, Yuan D, Zhou P, Hu L, Zhong D, Zhu S, Li J, Chen D, Wang K, Liang J, He Q, Sun J, Shi J, Yan L, Sands JM, Xie Z, Lian X, Xu D, Ran J, Yang B. High urea induces depression and LTP impairment through mTOR signalling suppression caused by carbamylation. EBioMedicine. 2019 Oct; 48:478-490.
Olga Tymofiyeva, Justin Yuan, Roma Kidambi, Chiung-Yu Huang, Eva Henje Blom, Mark Rubinstein, Duan Xu, Tony T. Yang. 4.32 SMARTPHONE DEPENDENCE, BRAIN CONNECTIVITY, AND LINKS TO DEPRESSION IN ADOLESCENTS. Journal of the American Academy of Child & Adolescent Psychiatry. 2019 Oct 1; 58(10):s229-s230.
Sun Q, Wang M, Li X, Jin C, Zhang H, Zhang Y, Wu F, Liu Z, Wang X, Liu C, Wei X, Xu D, Yang J. Detection of occult abnormalities in the deep gray matter nuclei of neonates with punctate white matter lesions by magnetic resonance spectroscopy. Neuroradiology. 2019 Dec; 61(12):1447-1456.
Cao P, Liu J, Tang S, Leynes AP, Lupo JM, Xu D, Larson PEZ. Technical Note: Simultaneous segmentation and relaxometry for MRI through multitask learning. Med Phys. 2019 Oct; 46(10):4610-4621.
Tymofiyeva O, Yuan JP, Huang CY, Connolly CG, Henje Blom E, Xu D, Yang TT. Application of machine learning to structural connectome to predict symptom reduction in depressed adolescents with cognitive behavioral therapy (CBT). Neuroimage Clin. 2019; 23:101914.
Mammoli D, Gordon J, Autry A, Larson PEZ, Li Y, Chen HY, Chung B, Shin P, Van Criekinge M, Carvajal L, Slater JB, Bok R, Crane J, Xu D, Chang S, Vigneron DB. Kinetic Modeling of Hyperpolarized Carbon-13 Pyruvate Metabolism in the Human Brain. IEEE Trans Med Imaging. 2020 02; 39(2):320-327.
Hsieh A, Tabbutt S, Xu D, Barkovich AJ, Miller S, McQuillen P, Peyvandi S. Impact of Perioperative Brain Injury and Development on Feeding Modality in Infants With Single Ventricle Heart Disease. J Am Heart Assoc. 2019 05 21; 8(10):e012291.
Adam Autry, Ilwoo Park, Hsin-Yu Chen, Jeremy Gordon, Cassie Kline-Nunnally, Daniel Vigneron, Janine Lupo, Yan Li, Duan Xu, Sabine Mueller. DIPG-31. FEASIBILITY OF HYPERPOLARIZED 13C METABOLIC IMAGING IN PEDIATRIC PATIENTS WITH DIPG AND OTHER CNS CANCERS. Neuro-Oncology. 2019 Apr 23; 21(Supplement_2):ii75-ii75.
Justin Yuan, Melanie Morrison, Angela Jakary, Sabine Mueller, Olga Tymofiyeva, Duan Xu, Janine Lupo. MEDU-15. STRUCTURAL BRAIN NETWORK PROPERTIES AND COGNITIVE IMPAIRMENT IN ADOLESCENTS AFTER RADIATION THERAPY. Neuro-Oncology. 2019 Apr 23; 21(Supplement_2):ii106-ii106.
Mikrogeorgiou A, Xu D, Ferriero DM, Vannucci SJ. Assessing Cerebral Metabolism in the Immature Rodent: From Extracts to Real-Time Assessments. Dev Neurosci. 2018; 40(5-6):463-474.
Autry AW, Gordon JW, Carvajal L, Mareyam A, Chen HY, Park I, Mammoli D, Vareth M, Chang SM, Wald LL, Xu D, Vigneron DB, Nelson SJ, Li Y. Comparison between 8- and 32-channel phased-array receive coils for in vivo hyperpolarized 13 C imaging of the human brain. Magn Reson Med. 2019 08; 82(2):833-841.
Anyir Hsieh, Sarah Tabbutt, Duan Xu, Patrick McQuillen, Shabnam Peyvandi. THE IMPACT OF PERIOPERATIVE BRAIN INJURY AND DEVELOPMENT ON FEEDING TUBE DEPENDENCY IN INTER-STAGE SINGLE VENTRICLE PATIENTS. Journal of the American College of Cardiology. 2019 Mar 1; 73(9):633.
Zhu Z, Zhu X, Ohliger MA, Tang S, Cao P, Carvajal L, Autry AW, Li Y, Kurhanewicz J, Chang S, Aggarwal R, Munster P, Xu D, Larson PEZ, Vigneron DB, Gordon JW. Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies. J Magn Reson. 2019 04; 301:73-79.
Yuan JP, Henje Blom E, Flynn T, Chen Y, Ho TC, Connolly CG, Dumont Walter RA, Yang TT, Xu D, Tymofiyeva O. Test-Retest Reliability of Graph Theoretic Metrics in Adolescent Brains. Brain Connect. 2019 03; 9(2):144-154.
Kamino D, Chau V, Studholme C, Liu M, Xu D, Barkovich AJ, Ferriero DM, Miller SP, Brant R, Tam EWY. Plasma cholesterol levels and brain development in preterm newborns. Pediatr Res. 2019 02; 85(3):299-304.
Gordon JW, Chen HY, Autry A, Park I, Van Criekinge M, Mammoli D, Milshteyn E, Bok R, Xu D, Li Y, Aggarwal R, Chang S, Slater JB, Ferrone M, Nelson S, Kurhanewicz J, Larson PEZ, Vigneron DB. Translation of Carbon-13 EPI for hyperpolarized MR molecular imaging of prostate and brain cancer patients. Magn Reson Med. 2019 04; 81(4):2702-2709.
Olga Tymofiyeva, Justin Yuan, Colm Connolly, Eva Henje Blom, Duan Xu, Tony T. Yang. 5.48 Using MRI to Predict Depression Symptom Improvement in Depressed Adolescents Undergoing Cbt. Journal of the American Academy of Child & Adolescent Psychiatry. 2018 Oct 1; 57(10):s242.
Barkovich MJ, Tan CH, Nillo RM, Li Y, Xu D, Glastonbury CM, Glenn OA, Dillon WP, Hess CP, Mueller S, Kline C, Dale AM, Jernigan TL, Sugrue LP, Barkovich AJ, Desikan RS. Abnormal Morphology of Select Cortical and Subcortical Regions in Neurofibromatosis Type 1. Radiology. 2018 11; 289(2):499-508.
Peyvandi S, Chau V, Guo T, Xu D, Glass HC, Synnes A, Poskitt K, Barkovich AJ, Miller SP, McQuillen PS. Neonatal Brain Injury and Timing of Neurodevelopmental Assessment in Patients With Congenital Heart Disease. J Am Coll Cardiol. 2018 05 08; 71(18):1986-1996.
Barkovich MJ, Li Y, Desikan RS, Barkovich AJ, Xu D. Challenges in pediatric neuroimaging. Neuroimage. 2019 01 15; 185:793-801.
Whitnee Hogan, Duan Xu, Anita Moon-Grady, Patrick McQuillen, Shabnam Peyvandi. FETAL CARDIOVASCULAR PHYSIOLOGY AND POSTNATAL BRAIN DEVELOPMENT AND INJURY IN CRITICAL CONGENITAL HEART DISEASE. Journal of the American College of Cardiology. 2018 Mar 1; 71(11):a573.
Tymofiyeva O, Henje Blom E, Ho TC, Connolly CG, Lindqvist D, Wolkowitz OM, Lin J, LeWinn KZ, Sacchet MD, Han LKM, Yuan JP, Bhandari SP, Xu D, Yang TT. High levels of mitochondrial DNA are associated with adolescent brain structural hypoconnectivity and increased anxiety but not depression. J Affect Disord. 2018 05; 232:283-290.
Park I, Larson PEZ, Gordon JW, Carvajal L, Chen HY, Bok R, Van Criekinge M, Ferrone M, Slater JB, Xu D, Kurhanewicz J, Vigneron DB, Chang S, Nelson SJ. Development of methods and feasibility of using hyperpolarized carbon-13 imaging data for evaluating brain metabolism in patient studies. Magn Reson Med. 2018 09; 80(3):864-873.
Boucneau T, Cao P, Tang S, Han M, Xu D, Henry RG, Larson PEZ. In vivo characterization of brain ultrashort-T2 components. Magn Reson Med. 2018 08; 80(2):726-735.
Tan YL, Kim H, Lee S, Tihan T, Ver Hoef L, Mueller SG, Barkovich AJ, Xu D, Knowlton R. Quantitative surface analysis of combined MRI and PET enhances detection of focal cortical dysplasias. Neuroimage. 2018 02 01; 166:10-18.
Kim H, Kim JH, Possin KL, Winer J, Geschwind MD, Xu D, Hess CP. Surface-based morphometry reveals caudate subnuclear structural damage in patients with premotor Huntington disease. Brain Imaging Behav. 2017 Oct; 11(5):1365-1372.
Peyvandi S, Kim H, Lau J, Barkovich AJ, Campbell A, Miller S, Xu D, McQuillen P. The association between cardiac physiology, acquired brain injury, and postnatal brain growth in critical congenital heart disease. J Thorac Cardiovasc Surg. 2018 01; 155(1):291-300.e3.
Shapiro KA, Kim H, Mandelli ML, Rogers EE, Gano D, Ferriero DM, Barkovich AJ, Gorno-Tempini ML, Glass HC, Xu D. Early changes in brain structure correlate with language outcomes in children with neonatal encephalopathy. Neuroimage Clin. 2017; 15:572-580.
Milano M, Guzzi PH, Tymofieva O, Xu D, Hess C, Veltri P, Cannataro M. An extensive assessment of network alignment algorithms for comparison of brain connectomes. BMC Bioinformatics. 2017 Jun 06; 18(Suppl 6):235.
Barkovich MJ, Xu D, Desikan RS, Williams C, Barkovich AJ. Pediatric neuro MRI: tricks to minimize sedation. Pediatr Radiol. 2018 01; 48(1):50-55.
Possin KL, Kim H, Geschwind MD, Moskowitz T, Johnson ET, Sha SJ, Apple A, Xu D, Miller BL, Finkbeiner S, Hess CP, Kramer JH. Egocentric and allocentric visuospatial working memory in premotor Huntington's disease: A double dissociation with caudate and hippocampal volumes. Neuropsychologia. 2017 Jul 01; 101:57-64.
Hosung Kim, Yee-Leng Tan, Seunghyun Lee, Anthony James Barkovich, Duan Xu, Robert Knowlton. Surface-Wise Texture Patch Analysis of Combined MRI and PET to Detect MRI-Negative Focal Cortical Dysplasia. Medical Image Computing and Computer Assisted Intervention - MICCAI 2017. 2017 Jan 1; 10433:212-220.
Paredes MF, James D, Gil-Perotin S, Kim H, Cotter JA, Ng C, Sandoval K, Rowitch DH, Xu D, McQuillen PS, Garcia-Verdugo JM, Huang EJ, Alvarez-Buylla A. Extensive migration of young neurons into the infant human frontal lobe. Science. 2016 Oct 07; 354(6308).
Tymofiyeva O, Connolly CG, Ho TC, Sacchet MD, Henje Blom E, LeWinn KZ, Xu D, Yang TT. DTI-based connectome analysis of adolescents with major depressive disorder reveals hypoconnectivity of the right caudate. J Affect Disord. 2017 Jan 01; 207:18-25.
Semple BD, Sadjadi R, Carlson J, Chen Y, Xu D, Ferriero DM, Noble-Haeusslein LJ. Long-Term Anesthetic-Dependent Hypoactivity after Repetitive Mild Traumatic Brain Injuries in Adolescent Mice. Dev Neurosci. 2016; 38(3):220-238.
Gano D, Ho ML, Partridge JC, Glass HC, Xu D, Barkovich AJ, Ferriero DM. Antenatal Exposure to Magnesium Sulfate Is Associated with Reduced Cerebellar Hemorrhage in Preterm Newborns. J Pediatr. 2016 Nov; 178:68-74.
Kansagra AP, Mabray MC, Ferriero DM, Barkovich AJ, Xu D, Hess CP. Microstructural maturation of white matter tracts in encephalopathic neonates. Clin Imaging. 2016 Sep-Oct; 40(5):1009-13.
Kim H, Lepage C, Maheshwary R, Jeon S, Evans AC, Hess CP, Barkovich AJ, Xu D. NEOCIVET: Towards accurate morphometry of neonatal gyrification and clinical applications in preterm newborns. Neuroimage. 2016 Sep; 138:28-42.
Gao J, Li X, Li Y, Zeng L, Jin C, Sun Q, Xu D, Yu B, Yang J. Differentiating T2 hyperintensity in neonatal white matter by two-compartment model of diffusional kurtosis imaging. Sci Rep. 2016 Apr 14; 6:24473.
Peyvandi S, De Santiago V, Chakkarapani E, Chau V, Campbell A, Poskitt KJ, Xu D, Barkovich AJ, Miller S, McQuillen P. Association of Prenatal Diagnosis of Critical Congenital Heart Disease With Postnatal Brain Development and the Risk of Brain Injury. JAMA Pediatr. 2016 Apr; 170(4):e154450.
Tam EW, Chau V, Barkovich AJ, Ferriero DM, Miller SP, Rogers EE, Grunau RE, Synnes AR, Xu D, Foong J, Brant R, Innis SM. Early postnatal docosahexaenoic acid levels and improved preterm brain development. Pediatr Res. 2016 05; 79(5):723-30.
Kim H, Gano D, Ho ML, Guo XM, Unzueta A, Hess C, Ferriero DM, Xu D, Barkovich AJ. Hindbrain regional growth in preterm newborns and its impairment in relation to brain injury. Hum Brain Mapp. 2016 Feb; 37(2):678-88.
Chen Y, Kim H, Bok R, Sukumar S, Mu X, Sheldon RA, Barkovich AJ, Ferriero DM, Xu D. Pyruvate to Lactate Metabolic Changes during Neurodevelopment Measured Dynamically Using Hyperpolarized 13C Imaging in Juvenile Murine Brain. Dev Neurosci. 2016; 38(1):34-40.
Wen Q, Kelley DA, Banerjee S, Lupo JM, Chang SM, Xu D, Hess CP, Nelson SJ. Clinically feasible NODDI characterization of glioma using multiband EPI at 7 T. Neuroimage Clin. 2015; 9:291-9.
Chen Y, Tymofiyeva O, Hess CP, Xu D. Effects of rejecting diffusion directions on tensor-derived parameters. Neuroimage. 2015 Apr 01; 109:160-70.
Hosung Kim, Claude Lepage, Alan C. Evans, A. James Barkovich, Duan Xu. NEOCIVET: Extraction of Cortical Surface and Analysis of Neonatal Gyrification Using a Modified CIVET Pipeline. Medical Image Computing and Computer-Assisted Intervention – MICCAI 2015. 2015 Jan 1; 9351:571-579.
Stanco A, Pla R, Vogt D, Chen Y, Mandal S, Walker J, Hunt RF, Lindtner S, Erdman CA, Pieper AA, Hamilton SP, Xu D, Baraban SC, Rubenstein JL. NPAS1 represses the generation of specific subtypes of cortical interneurons. Neuron. 2014 Dec 03; 84(5):940-53.
Gano D, Andersen SK, Partridge JC, Bonifacio SL, Xu D, Glidden DV, Ferriero DM, Barkovich AJ, Glass HC. Diminished white matter injury over time in a cohort of premature newborns. J Pediatr. 2015 Jan; 166(1):39-43.
Tymofiyeva O, Hess CP, Xu D, Barkovich AJ. Structural MRI connectome in development: challenges of the changing brain. Br J Radiol. 2014 Jul; 87(1039):20140086.
Tymofiyeva O, Ziv E, Barkovich AJ, Hess CP, Xu D. Brain without anatomy: construction and comparison of fully network-driven structural MRI connectomes. PLoS One. 2014; 9(5):e96196.
Liu J, Glenn OA, Xu D. Fast, free-breathing, in vivo fetal imaging using time-resolved 3D MRI technique: preliminary results. Quant Imaging Med Surg. 2014 Apr; 4(2):123-8.
Ziv E, Tymofiyeva O, Ferriero DM, Barkovich AJ, Hess CP, Xu D. A machine learning approach to automated structural network analysis: application to neonatal encephalopathy. PLoS One. 2013; 8(11):e78824.
Dimitropoulos A, McQuillen PS, Sethi V, Moosa A, Chau V, Xu D, Brant R, Azakie A, Campbell A, Barkovich AJ, Poskitt KJ, Miller SP. Brain injury and development in newborns with critical congenital heart disease. Neurology. 2013 Jul 16; 81(3):241-8.
Tymofiyeva O, Hess CP, Ziv E, Lee PN, Glass HC, Ferriero DM, Barkovich AJ, Xu D. A DTI-based template-free cortical connectome study of brain maturation. PLoS One. 2013; 8(5):e63310.
Dedini RD, Karacozoff AM, Shellock FG, Xu D, McClellan RT, Pekmezci M. MRI issues for ballistic objects: information obtained at 1.5-, 3- and 7-Tesla. Spine J. 2013 Jul; 13(7):815-22.
Sethi V, Tabbutt S, Dimitropoulos A, Harris KC, Chau V, Poskitt K, Campbell A, Azakie A, Xu D, Barkovich AJ, Miller SP, McQuillen PS. Single-ventricle anatomy predicts delayed microstructural brain development. Pediatr Res. 2013 May; 73(5):661-7.
Xu D, Mukherjee P, Barkovich AJ. Pediatric brain injury: can DTI scalars predict functional outcome? Pediatr Radiol. 2013 Jan; 43(1):55-9.
JG Feenstra, PN Lee, D Xu, SL Bonifacio, DM Ferriero, AJ Barkovich, HC Glass. 1086 Seizures are Associated with Altered Hippocampal Diffusion in Neonates with Hypoxic-Ischemic Encephalopathy. Archives of Disease in Childhood. 2012 Oct 1; 97(Suppl 2):a311.
Bian W, Harter K, Hammond-Rosenbluth KE, Lupo JM, Xu D, Kelley DA, Vigneron DB, Nelson SJ, Pelletier D. A serial in vivo 7T magnetic resonance phase imaging study of white matter lesions in multiple sclerosis. Mult Scler. 2013 Jan; 19(1):69-75.
Glenn OA, Cuneo AA, Barkovich AJ, Hashemi Z, Bartha AI, Xu D. Malformations of cortical development: diagnostic accuracy of fetal MR imaging. Radiology. 2012 Jun; 263(3):843-55.
Tymofiyeva O, Hess CP, Ziv E, Tian N, Bonifacio SL, McQuillen PS, Ferriero DM, Barkovich AJ, Xu D. Towards the "baby connectome": mapping the structural connectivity of the newborn brain. PLoS One. 2012; 7(2):e31029.
Wu B, Zhang X, Wang C, Li Y, Pang Y, Lu J, Xu D, Majumdar S, Nelson SJ, Vigneron DB. Flexible transceiver array for ultrahigh field human MR imaging. Magn Reson Med. 2012 Oct; 68(4):1332-8.
Duan Xu, Daniel B. Vigneron. High Field MR Spectroscopy: Investigating Human Metabolite Levels at High Spectral and Spatial Resolution. High-Field MR Imaging. 2012 Jan 1; 215-228.
Pang Y, Xie Z, Xu D, Kelley DA, Nelson SJ, Vigneron DB, Zhang X. A dual-tuned quadrature volume coil with mixed ?/2 and ?/4 microstrip resonators for multinuclear MRSI at 7 T. Magn Reson Imaging. 2012 Feb; 30(2):290-8.
Wang C, Li Y, Wu B, Xu D, Nelson SJ, Vigneron DB, Zhang X. A practical multinuclear transceiver volume coil for in vivo MRI/MRS at 7 T. Magn Reson Imaging. 2012 Jan; 30(1):78-84.
Takanashi J, Somazawa F, Maruyama K, Terada H, Xu D, Barkovich AJ. Metabolic changes in early childhood using LCModel with corrected water scaling method. J Magn Reson Imaging. 2012 Jan; 35(1):174-80.
Pang Y, Xie Z, Li Y, Xu D, Vigneron D, Zhang X. Resonant Mode Reduction in Radiofrequency Volume Coils for Ultrahigh Field Magnetic Resonance Imaging. Materials (Basel). 2011 Jul 28; 4(8):1333-1344.
Sonia L. Bonifacio, Hannah C. Glass, Juliana Vanderpluym, Ashish T. Agrawal, Duan Xu, A. James Barkovich, Donna M. Ferriero. Perinatal Events and Early Magnetic Resonance Imaging in Therapeutic Hypothermia. Obstetrical & Gynecological Survey. 2011 Jun 1; 66(6):334-336.
Jacob FD, Habas PA, Kim K, Corbett-Detig J, Xu D, Studholme C, Glenn OA. Fetal hippocampal development: analysis by magnetic resonance imaging volumetry. Pediatr Res. 2011 May; 69(5 Pt 1):425-9.
Xu D, Bonifacio SL, Charlton NN, P Vaughan C, Lu Y, Ferriero DM, Vigneron DB, Barkovich AJ. MR spectroscopy of normative premature newborns. J Magn Reson Imaging. 2011 Feb; 33(2):306-11.
Li Y, Pang Y, Vigneron D, Glenn O, Xu D, Zhang X. Investigation of multichannel phased array performance for fetal MR imaging on 1.5T clinical MR system. Quant Imaging Med Surg. 2011 Jan 01; 1(1):24-30.
Bonifacio SL, Glass HC, Chau V, Berman JI, Xu D, Brant R, Barkovich AJ, Poskitt KJ, Miller SP, Ferriero DM. Extreme premature birth is not associated with impaired development of brain microstructure. J Pediatr. 2010 Nov; 157(5):726-32.e1.
Bonifacio SL, Glass HC, Vanderpluym J, Agrawal AT, Xu D, Barkovich AJ, Ferriero DM. Perinatal events and early magnetic resonance imaging in therapeutic hypothermia. J Pediatr. 2011 Mar; 158(3):360-5.
Tropp J, Lupo JM, Chen A, Calderon P, McCune D, Grafendorfer T, Ozturk-Isik E, Larson PE, Hu S, Yen YF, Robb F, Bok R, Schulte R, Xu D, Hurd R, Vigneron D, Nelson S. Multi-channel metabolic imaging, with SENSE reconstruction, of hyperpolarized [1-(13)C] pyruvate in a live rat at 3.0 tesla on a clinical MR scanner. J Magn Reson. 2011 Jan; 208(1):171-7.
Kerchner GA, Hess CP, Hammond-Rosenbluth KE, Xu D, Rabinovici GD, Kelley DA, Vigneron DB, Nelson SJ, Miller BL. Hippocampal CA1 apical neuropil atrophy in mild Alzheimer disease visualized with 7-T MRI. Neurology. 2010 Oct 12; 75(15):1381-7.
von Morze C, Kelley DA, Shepherd TM, Banerjee S, Xu D, Hess CP. Reduced field-of-view diffusion-weighted imaging of the brain at 7 T. Magn Reson Imaging. 2010 Dec; 28(10):1541-5.
Geoffrey A. Kerchner, Christopher P. Hess, Kathryn Hammond-Rosenbluth, Duan Xu, Douglas A.C. Kelley, Daniel P. Vigneron, Sarah J. Nelson, Bruce L. Miller. Hippocampal neuropil atrophy in early Alzheimer's disease: A 7T MRI study. Alzheimer's & Dementia. 2010 Jul 1; 6(4):s59-s60.
Xu D, Vigneron D. Magnetic resonance spectroscopy imaging of the newborn brain--a technical review. Semin Perinatol. 2010 Feb; 34(1):20-7.
Xu D, Lee MC, Carballido-Gamio J, Barkovich M, Majumdar S, Vigneron DB, Nelson SJ. Quantitative analysis of spatial distortions of diffusion techniques at 3T. Magn Reson Imaging. 2010 Apr; 28(3):451-4.
Berman JI, Hamrick SE, McQuillen PS, Studholme C, Xu D, Henry RG, Hornberger LK, Glenn OA. Diffusion-weighted imaging in fetuses with severe congenital heart defects. AJNR Am J Neuroradiol. 2011 Feb; 32(2):E21-2.
Glenn OA, Quiroz EM, Berman JI, Studholme C, Xu D. Diffusion-weighted imaging in fetuses with unilateral cortical malformations and callosal agenesis. AJNR Am J Neuroradiol. 2010 Jun; 31(6):1100-2.
Wu B, Wang C, Kelley DA, Xu D, Vigneron DB, Nelson SJ, Zhang X. Shielded microstrip array for 7T human MR imaging. IEEE Trans Med Imaging. 2010 Jan; 29(1):179-84.
Ozturk-Isik E, Chen AP, Crane JC, Bian W, Xu D, Han ET, Chang SM, Vigneron DB, Nelson SJ. 3D sensitivity encoded ellipsoidal MR spectroscopic imaging of gliomas at 3T. Magn Reson Imaging. 2009 Nov; 27(9):1249-57.
Wu B, Wang C, Krug R, Kelley DA, Xu D, Pang Y, Banerjee S, Vigneron DB, Nelson SJ, Majumdar S, Zhang X. 7T human spine imaging arrays with adjustable inductive decoupling. IEEE Trans Biomed Eng. 2010 Feb; 57(2):397-403.
Tam EW, Ferriero DM, Xu D, Berman JI, Vigneron DB, Barkovich AJ, Miller SP. Cerebellar development in the preterm neonate: effect of supratentorial brain injury. Pediatr Res. 2009 Jul; 66(1):102-6.
Schneider MM, Berman JI, Baumer FM, Glass HC, Jeng S, Jeremy RJ, Esch M, Biran V, Barkovich AJ, Studholme C, Xu D, Glenn OA. Normative apparent diffusion coefficient values in the developing fetal brain. AJNR Am J Neuroradiol. 2009 Oct; 30(9):1799-803.
Zhao J, Krug R, Xu D, Lu Y, Link TM. MRI of the spine: image quality and normal-neoplastic bone marrow contrast at 3 T versus 1.5 T. AJR Am J Roentgenol. 2009 Apr; 192(4):873-80.
Osorio JA, Xu D, Cunningham CH, Chen A, Kerr AB, Pauly JM, Vigneron DB, Nelson SJ. Design of cosine modulated very selective suppression pulses for MR spectroscopic imaging at 3T. Magn Reson Med. 2009 Mar; 61(3):533-40.
Metcalf M, Xu D, Okuda DT, Carvajal L, Srinivasan R, Kelley DA, Mukherjee P, Nelson SJ, Vigneron DB, Pelletier D. High-resolution phased-array MRI of the human brain at 7 tesla: initial experience in multiple sclerosis patients. J Neuroimaging. 2010 Apr; 20(2):141-7.
Chen AP, Tropp J, Hurd RE, Van Criekinge M, Carvajal LG, Xu D, Kurhanewicz J, Vigneron DB. In vivo hyperpolarized 13C MR spectroscopic imaging with 1H decoupling. J Magn Reson. 2009 Mar; 197(1):100-6.
Lupo JM, Banerjee S, Hammond KE, Kelley DA, Xu D, Chang SM, Vigneron DB, Majumdar S, Nelson SJ. GRAPPA-based susceptibility-weighted imaging of normal volunteers and patients with brain tumor at 7 T. Magn Reson Imaging. 2009 May; 27(4):480-8.
von Morze C, Purcell DD, Banerjee S, Xu D, Mukherjee P, Kelley DA, Majumdar S, Vigneron DB. High-resolution intracranial MRA at 7T using autocalibrating parallel imaging: initial experience in vascular disease patients. Magn Reson Imaging. 2008 Dec; 26(10):1329-33.
Xu D, Cunningham CH, Chen AP, Li Y, Kelley DA, Mukherjee P, Pauly JM, Nelson SJ, Vigneron DB. Phased array 3D MR spectroscopic imaging of the brain at 7 T. Magn Reson Imaging. 2008 Nov; 26(9):1201-6.
Chen AP, Kurhanewicz J, Bok R, Xu D, Joun D, Zhang V, Nelson SJ, Hurd RE, Vigneron DB. Feasibility of using hyperpolarized [1-13C]lactate as a substrate for in vivo metabolic 13C MRSI studies. Magn Reson Imaging. 2008 Jul; 26(6):721-6.
Cunningham CH, Chen AP, Lustig M, Hargreaves BA, Lupo J, Xu D, Kurhanewicz J, Hurd RE, Pauly JM, Nelson SJ, Vigneron DB. Pulse sequence for dynamic volumetric imaging of hyperpolarized metabolic products. J Magn Reson. 2008 Jul; 193(1):139-46.
Banerjee S, Krug R, Carballido-Gamio J, Kelley DA, Xu D, Vigneron DB, Majumdar S. Rapid in vivo musculoskeletal MR with parallel imaging at 7T. Magn Reson Med. 2008 Mar; 59(3):655-60.
Krug R, Carballido-Gamio J, Banerjee S, Stahl R, Carvajal L, Xu D, Vigneron D, Kelley DA, Link TM, Majumdar S. In vivo bone and cartilage MRI using fully-balanced steady-state free-precession at 7 tesla. Magn Reson Med. 2007 Dec; 58(6):1294-8.
Miller SP, McQuillen PS, Hamrick S, Xu D, Glidden DV, Charlton N, Karl T, Azakie A, Ferriero DM, Barkovich AJ, Vigneron DB. Abnormal brain development in newborns with congenital heart disease. N Engl J Med. 2007 Nov 08; 357(19):1928-38.
Hammond KE, Lupo JM, Xu D, Metcalf M, Kelley DA, Pelletier D, Chang SM, Mukherjee P, Vigneron DB, Nelson SJ. Development of a robust method for generating 7.0 T multichannel phase images of the brain with application to normal volunteers and patients with neurological diseases. Neuroimage. 2008 Feb 15; 39(4):1682-92.
von Morze C, Xu D, Purcell DD, Hess CP, Mukherjee P, Saloner D, Kelley DA, Vigneron DB. Intracranial time-of-flight MR angiography at 7T with comparison to 3T. J Magn Reson Imaging. 2007 Oct; 26(4):900-4.
Mukherjee P, Hess CP, Xu D, Han ET, Kelley DA, Vigneron DB. Development and initial evaluation of 7-T q-ball imaging of the human brain. Magn Reson Imaging. 2008 Feb; 26(2):171-80.
Osorio JA, Ozturk-Isik E, Xu D, Cha S, Chang S, Berger MS, Vigneron DB, Nelson SJ. 3D 1H MRSI of brain tumors at 3.0 Tesla using an eight-channel phased-array head coil. J Magn Reson Imaging. 2007 Jul; 26(1):23-30.
Chen AP, Cunningham CH, Ozturk-Isik E, Xu D, Hurd RE, Kelley DA, Pauly JM, Kurhanewicz J, Nelson SJ, Vigneron DB. High-speed 3T MR spectroscopic imaging of prostate with flyback echo-planar encoding. J Magn Reson Imaging. 2007 Jun; 25(6):1288-92.
Cornelius von Morze, James Tropp, Suchandrima Banerjee, Duan Xu, Kostas Karpodinis, Lucas Carvajal, Christopher P. Hess, Pratik Mukherjee, Sharmila Majumdar, Daniel B. Vigneron. An eight-channel, nonoverlapping phased array coil with capacitive decoupling for parallel MRI at 3 T. Concepts in Magnetic Resonance Part B. 2007 Feb 1; 31B(1):37-43.
Carballido-Gamio J, Xu D, Newitt D, Han ET, Vigneron DB, Majumdar S. Single-shot fast spin-echo diffusion tensor imaging of the lumbar spine at 1.5 and 3 T. Magn Reson Imaging. 2007 Jun; 25(5):665-70.
Li Y, Osorio JA, Ozturk-Isik E, Chen AP, Xu D, Crane JC, Cha S, Chang S, Berger MS, Vigneron DB, Nelson SJ. Considerations in applying 3D PRESS H-1 brain MRSI with an eight-channel phased-array coil at 3 T. Magn Reson Imaging. 2006 Dec; 24(10):1295-302.
Hess CP, Mukherjee P, Han ET, Xu D, Vigneron DB. Q-ball reconstruction of multimodal fiber orientations using the spherical harmonic basis. Magn Reson Med. 2006 Jul; 56(1):104-17.
Chen AP, Cunningham CH, Kurhanewicz J, Xu D, Hurd RE, Pauly JM, Carvajal L, Karpodinis K, Vigneron DB. High-resolution 3D MR spectroscopic imaging of the prostate at 3 T with the MLEV-PRESS sequence. Magn Reson Imaging. 2006 Sep; 24(7):825-32.
Barkovich AJ, Miller SP, Bartha A, Newton N, Hamrick SE, Mukherjee P, Glenn OA, Xu D, Partridge JC, Ferriero DM, Vigneron DB. MR imaging, MR spectroscopy, and diffusion tensor imaging of sequential studies in neonates with encephalopathy. AJNR Am J Neuroradiol. 2006 Mar; 27(3):533-47.
Lupo JM, Banerjee S, Kelley D, Xu D, Vigneron DB, Majumdar S, Nelson SJ. Partially-parallel, susceptibility-weighted MR imaging of brain vasculature at 7 Tesla using sensitivity encoding and an autocalibrating parallel technique. Conf Proc IEEE Eng Med Biol Soc. 2006; 2006:747-50.
Xu D, Chen AP, Cunningham C, Osorio JA, Nelson SJ, Vigneron DB. Spectroscopic imaging of the brain with phased-array coils at 3.0 T. Magn Reson Imaging. 2006 Jan; 24(1):69-74.
Cunningham CH, Vigneron DB, Chen AP, Xu D, Nelson SJ, Hurd RE, Kelley DA, Pauly JM. Design of flyback echo-planar readout gradients for magnetic resonance spectroscopic imaging. Magn Reson Med. 2005 Nov; 54(5):1286-9.
Cunningham CH, Vigneron DB, Marjanska M, Chen AP, Xu D, Hurd RE, Kurhanewicz J, Garwood M, Pauly JM. Sequence design for magnetic resonance spectroscopic imaging of prostate cancer at 3 T. Magn Reson Med. 2005 May; 53(5):1033-9.
Cunningham CH, Vigneron DB, Chen AP, Xu D, Hurd RE, Sailasuta N, Pauly JM. Design of symmetric-sweep spectral-spatial RF pulses for spectral editing. Magn Reson Med. 2004 Jul; 52(1):147-53.
Xu D, Henry RG, Mukherjee P, Carvajal L, Miller SP, Barkovich AJ, Vigneron DB. Single-shot fast spin-echo diffusion tensor imaging of the brain and spine with head and phased array coils at 1.5 T and 3.0 T. Magn Reson Imaging. 2004 Jul; 22(6):751-9.