Amie Lee, MD

Associate Professor
Assoc Prof Clinical Radiology
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Biography

Amie Lee, MD is an Associate Professor of Clinical Radiology in the Breast Imaging section in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. She received her medical degree from UCSF in 2009. She completed her residency in Diagnostic Radiology at the University of Washington in Seattle in 2014, followed by a fellowship in Breast Imaging at UCSF.

Dr. Lee’s research focus is on improving the delivery of high quality care to patients undergoing breast imaging. She also has a strong interest in resident and fellow education.

Expertise:
Breast Imaging

Specialty:
Breast Imaging and Intervention

Professional Interests:
Breast imaging, breast cancer, mammography, tomosynthesis, breast MRI, breast ultrasound, image-guided biopsy, quality improvement, medical education

Education and Training:
• Medical School: University of California, San Francisco
• Internship: Kaiser Permanente, Oakland, California
• Residency: University of Washington, Seattle
• Fellowship: University of California, San Francisco – Breast Imaging

Education

M.D., 2009 - School of Medicine, University of California, San Francisco

Publications

Brink L, Romero RA, Coombs L, Tilkin M, Mazaheri S, Gichoya J, Zaiman Z, Trivedi H, Medina A, Bizzo BC, Chang K, Kalpathy-Cramer J, Kalra MK, Astuto B, Ramirez C, Majumdar S, Lee AY, Lee CI, Cross NM, Chen PH, Ciancibello M, Chiunda A, Nachand D, Shah C, Wald C. Multi-institutional Evaluation and Training of Breast Density Classification AI Algorithm Using ACR Connect and AI-LAB. J Am Coll Radiol. 2024 Nov 15.
Chung M, Ton L, Lee AY. Forget Me Not: Incidental Findings on Breast MRI. J Breast Imaging. 2024 Jul 30; 6(4):430-448.
Lee AY, Friedewald SM. Clinical Implementation of AI in Screening Mammography: The Essential Role of Prospective Evaluation. Radiology. 2024 06; 311(3):e241124.
Tatem AR, Lee AY. Ectopic Abdominal Breast Tissue. J Breast Imaging. 2024 May 27; 6(3):330-331.
Hayward JH, Lee AY, Sickles EA, Ray KM. Prevalent vs Incident Screen: Why Does It Matter? J Breast Imaging. 2024 May 27; 6(3):232-237.
Xu K, Chung M, Hayward JH, Kelil T, Lee AY, Ray KM. MRI of the Lactating Breast. Radiographics. 2024 02; 44(2):e230129.
Hastings-Robinson A, Chung M, Hayward JH, Ray KM, Price ER, Navarro R, Joe BN, Lee AY. The role of digital mammographic surveillance for detection of asymptomatic recurrence in autologous flap reconstructions. Clin Imaging. 2024 Feb; 106:110062.
Sakafu L, Kiango V, Khasim Z, Shoo A, Ndossa M, Kagaruki G, Manyama D, Magandi J, Lee AY. Radiation safety in an era of diagnostic radiology growth in Africa: Lessons learned from Tanzania. Clin Imaging. 2023 Oct; 102:65-70.
Chung M, Calabrese E, Mongan J, Ray KM, Hayward JH, Kelil T, Sieberg R, Hylton N, Joe BN, Lee AY. Deep Learning to Simulate Contrast-enhanced Breast MRI of Invasive Breast Cancer. Radiology. 2023 Mar; 306(3):e239004.
Lee AY. Nipple-sparing Mastectomy in the Era of Neoadjuvant Systemic Therapy: The Accuracy of Preoperative MRI. Radiology. 2023 04; 307(2):e223297.
Chung M, Calabrese E, Mongan J, Ray KM, Hayward JH, Kelil T, Sieberg R, Hylton N, Joe BN, Lee AY. Deep Learning to Simulate Contrast-enhanced Breast MRI of Invasive Breast Cancer. Radiology. 2023 03; 306(3):e213199.
Sakafu LL, Philipo GS, Malichewe CV, Fundikira LS, Lwakatare FA, Van Loon K, Mushi BP, DeBoer RJ, Bialous SA, Lee AY. Delayed diagnostic evaluation of symptomatic breast cancer in sub-Saharan Africa: A qualitative study of Tanzanian women. PLoS One. 2022; 17(10):e0275639.
Karandikar A, Solberg A, Fung A, Lee AY, Farooq A, Taylor AC, Oliveira A, Narayan A, Senter A, Majid A, Tong A, McGrath AL, Malik A, Brown AL, Roberts A, Fleischer A, Vettiyil B, Zigmund B, Park B, Curran B, Henry C, Jaimes C, Connolly C, Robson C, Meltzer CC, Phillips CH, Dove C, Glastonbury C, Pomeranz C, Kirsch CFE, Burgan CM, Scher C, Tomblinson C, Fuss C, Santillan C, Daye D, Brown DB, Young DJ, Kopans D, Vargas D, Martin D, Thompson D, Jordan DW, Shatzkes D, Sun D, Mastrodicasa D, Smith E, Korngold E, Dibble EH, Arleo EK, Hecht EM, Morris E, Maltin EP, Cooke EA, Schwartz ES, Lehrman E, Sodagari F, Shah F, Doo FX, Rigiroli F, Vilanilam GK, Landinez G, Kim GG, Rahbar H, Choi H, Bandesha H, Ojeda-Fournier H, Ikuta I, Dragojevic I, Schroeder JLT, Ivanidze J, Katzen JT, Chiang J, Nguyen J, Robinson JD, Broder JC, Kemp J, Weaver JS, Conyers JM, Robbins JB, Leschied JR, Wen J, Park J, Mongan J, Perchik J, Barbero JPM, Jacob J, Ledbetter K, Macura KJ, Maturen KE, Frederick-Dyer K, Dodelzon K, Cort K, Kisling K, Babagbemi K, McGill KC, Chang KJ, Feigin K, Winsor KS, Seifert K, Patel K, Porter KK, Foley KM, Patel-Lippmann K, McIntosh LJ, Padilla L, Groner L, Harry LM, Ladd LM, Wang L, Spalluto LB, Mahesh M, Marx MV, Sugi MD, Sammer MBK, Sun M, Barkovich MJ, Miller MJ, Vella M, Davis MA, Englander MJ, Durst M, Oumano M, Wood MJ, McBee MP, Fischbein NJ, Kovalchuk N, Lall N, Eclov N, Madhuripan N, Ariaratnam NS, Vincoff NS, Kothary N, Yahyavi-Firouz-Abadi N, Brook OR, Glenn OA, Woodard PK, Mazaheri P, Rhyner P, Eby PR, Raghu P, Gerson RF, Patel R, Gutierrez RL, Gebhard R, Andreotti RF, Masum R, Woods R, Mandava S, Harrington SG, Parikh S, Chu S, Arora SS, Meyers SM, Prabhu S, Shams S, Pittman S, Patel SN, Payne S, Hetts SW, Hijaz TA, Chapman T, Loehfelm TW, Juang T, Clark TJ, Potigailo V, Shah V, Planz V, Kalia V, DeMartini W, Dillon WP, Gupta Y, Koethe Y, Hartley-Blossom Z, Wang ZJ, McGinty G, Haramati A, Allen LM, Germaine P. Radiologists staunchly support patient safety and autonomy, in opposition to the SCOTUS decision to overturn Roe v Wade. Clin Imaging. 2023 01; 93:117-121.
Weinfurtner RJ, Lee A, Vincenti K, Gundry K, Hoyt T, Klein K, Merkulov A, Mullen L, O'Brien S, Roubein D, Tseng J, Margolies L. Mentorship Interest in Breast Imaging: Survey Results From the Society of Breast Imaging. J Breast Imaging. 2022 Apr 15; 4(2):161-167.
Maggie Chung, Roberto Ruiz-Cordero, Amie Y. Lee, Bonnie N. Joe, Tatiana Kelil. MRI Evaluation of the Lactating Breast. Current Radiology Reports. 2022 Mar 23; 10(5):57-67.
Lee AY. Editorial Comment: Architectural Distortion on Digital Breast Tomosynthesis-to Excise or Not to Excise? AJR Am J Roentgenol. 2022 Jul; 219(1):54.
Lee AY, Ray KM. Surrogate Clinical End Points for Breast Cancer Screening Using Digital Breast Tomosynthesis. Radiology. 2022 05; 303(2):267-268.
Holtz JN, Woodard GA, Hayward JH, Ray KM, Kannan N, Greenwood HI, Joe BN, Lee AY. The Value of Targeted Ultrasound for the Primary Evaluation of Breast Symptoms in Pregnant Women of All Ages. J Breast Imaging. 2021 Sep 16; 3(5):556-563.
Taliaferro AS, Price ER, Hayward JH, Wong JM, Balassanian R, Fay JS, Freimanis RI, Joe BN, Lee AY. Utility and Outcomes of Preoperative Screening Breast MRI for Planned Bilateral Prophylactic Mastectomy in High-Risk Patients. AJR Am J Roentgenol. 2022 02; 218(2):241-248.
Greenwood HI, Price ER, Lee AY, Kelil T, Jones C, Le M, Jaswa EG. Outcomes of screening mammography performed prior to fertility treatment in women ages 40-49. Clin Imaging. 2021 Dec; 80:359-363.
Lee AY. Sustained Benefits of Abbreviated Breast MRI on Consecutive Screening Rounds. Radiology. 2021 04; 299(1):84-85.
Eckstein DA, Price ER, Hayward JH, Joe BN, Lee AY. Frequency and Outcomes of New Suspicious Lesions on Breast MRI in the Setting of Neoadjuvant Therapy. AJR Am J Roentgenol. 2021 03; 216(3):633-639.
Price ER, Vyas S, Lee AY, Wong JM, Joe BN, Ray KM. Intermediary clip placement to assist accurate axillary lymph node localization. Clin Imaging. 2021 May; 73:96-100.
Chapman MC, Lee AY, Hayward JH, Joe BN, Price ER. Superparamagnetic Iron Oxide Sentinel Node Tracer Injection: Effects on Breast MRI Quality. J Breast Imaging. 2020 Nov 21; 2(6):577-582.
Chung M, Hayward JH, Woodard GA, Knobel A, Greenwood HI, Ray KM, Joe BN, Lee AY. US as the Primary Imaging Modality in the Evaluation of Palpable Breast Masses in Breastfeeding Women, Including Those of Advanced Maternal Age. Radiology. 2020 11; 297(2):316-324.
Sohn JH, Chillakuru YR, Lee S, Lee AY, Kelil T, Hess CP, Seo Y, Vu T, Joe BN. An Open-Source, Vender Agnostic Hardware and Software Pipeline for Integration of Artificial Intelligence in Radiology Workflow. J Digit Imaging. 2020 08; 33(4):1041-1046.
Wright AG, Hayward JH, Price ER, Ray KM, Joe BN, Lee AY. Primum non nocere: Utility and outcomes of pediatric breast ultrasound. Clin Imaging. 2020 Dec; 68:131-135.
Hayward JH, Ray KM, Price ER, Sickles EA, Conlon K, Lobach I, Joe BN, Lee AY. Performance of screening MRI in high risk patients at initial versus subsequent screen. Clin Imaging. 2020 Oct; 66:87-92.
Chapman MC, Hayward JH, Woodard GA, Joe BN, Lee AY. The Role of Breast MRI in Detecting Asymptomatic Recurrence After Therapeutic Mastectomy. AJR Am J Roentgenol. 2020 07; 215(1):254-261.
Linden OE, Hayward JH, Price ER, Kelil T, Joe BN, Lee AY. Utility of Diagnostic Mammography as the Primary Imaging Modality for Palpable Lumps in Women With Almost Entirely Fatty Breasts. AJR Am J Roentgenol. 2020 04; 214(4):938-944.
Lee AY, Plecha D, Woodard GA, Price ER, Hayward JH, Mark S, Joe BN. Utilization of Patient Navigators in Breast Imaging Facilities Across the United States: A Survey of Breast Imaging Radiologists. J Breast Imaging. 2020 Feb 04; 2(1):16-21.
Greenwood HI, Greenwood EA, Lee AY, Price ER. Outcomes of screening mammography in women less than 40 prior to fertility treatment: a retrospective pilot study. Clin Imaging. 2020 Feb; 59(2):109-113.
Chen CA, Hayward JH, Woodard GA, Ray KM, Starr CJ, Hylton NM, Joe BN, Lee AY. Complete Breast MRI Response to Neoadjuvant Chemotherapy and Prediction of Pathologic Complete Response. J Breast Imaging. 2019 Sep 04; 1(3):217-222.
Dashevsky BZ, Hayward JH, Woodard GA, Joe BN, Lee AY. Utility and Outcomes of Imaging Evaluation for Palpable Lumps in the Postmastectomy Patient. AJR Am J Roentgenol. 2019 08; 213(2):464-472.
Lee AY, Navarro R, Busby LP, Greenwood HI, Bucknor MD, Ray KM, Joe BN. Characterization of Metastatic Sternal Lesions on Dynamic Contrast-Enhanced Breast MRI in Women with Invasive Breast Cancer. Acad Radiol. 2019 10; 26(10):1358-1362.
Lai YC, Ray KM, Lee AY, Hayward JH, Freimanis RI, Lobach IV, Joe BN. Microcalcifications Detected at Screening Mammography: Synthetic Mammography and Digital Breast Tomosynthesis versus Digital Mammography. Radiology. 2018 12; 289(3):630-638.
Ng DL, Vuhahula E, Zhang L, Waterhouse EG, White KL, Mushi BP, Nyeriga MS, Philipo GS, Mmbaga EJ, Sheth S, Van Loon K, Lee AY, Balassanian R. Efficacy of an Intensive, Ultrasound-Guided Fine-Needle Aspiration Biopsy Training Workshop in Tanzania. J Glob Oncol. 2018 10; 4:1-9.
Laguna B, Hayward JH, Lee AY, Joe BN, Ray KM. Paraneoplastic neurologic syndrome as a presentation of underlying breast malignancy. Breast J. 2018 11; 24(6):1038-1042.
Lee AY, Nguyen VT, Arasu VA, Greenwood HI, Ray KM, Joe BN, Price ER. Sonographic-MRI Correlation After Percutaneous Sampling of Targeted Breast Ultrasound Lesions: Initial Experiences With Limited-Sequence Unenhanced MRI for Postprocedural Clip Localization. AJR Am J Roentgenol. 2018 Apr; 210(4):927-934.
Qiao Y, Hayward JH, Balassanian R, Ray KM, Joe BN, Lee AY. Tuberculosis mastitis presenting as bilateral breast masses. Clin Imaging. 2018 Nov - Dec; 52:28-31.
Vignesh A. Arasu, Neeta Kannan, Priya M. Krishnarao, Gillian Kuehner, Ming C. Kuan, Joseph C. Kim, Bonnie N. Joe, Amie Y. Lee. Imaging the Breast in Pregnant or Lactating Women. Current Radiology Reports. 2018 Feb 1; 6(2):10.
Greenwood HI, Lee AY, Lobach IV, Carpentier BM, Freimanis RI, Strachowski LM. Clustered Microcysts on Breast Ultrasound: What Is an Appropriate Management Recommendation? AJR Am J Roentgenol. 2017 Dec; 209(6):W395-W399.
Lee AY, Joe BN, Price ER. The Predicament of the Probably Benign Breast MRI: Should We Rely on Intuition? Breast J. 2017 09; 23(5):501-503.
Foo ET, Lee AY, Ray KM, Woodard GA, Freimanis RI, Joe BN. Value of diagnostic imaging for the symptomatic male breast: Can we avoid unnecessary biopsies? Clin Imaging. 2017 Sep - Oct; 45:86-91.
Maglione KD, Lee AY, Ray KM, Joe BN, Balassanian R. Radiologic-Pathologic Correlation for Benign Results After MRI-Guided Breast Biopsy. AJR Am J Roentgenol. 2017 Aug; 209(2):442-453.
Chou SS, Hippe DS, Lee AY, Scherer K, Porrino JA, Davidson DJ, Chew FS, Ha AS. Gadolinium Contrast Enhancement Improves Confidence in Diagnosing Recurrent Soft Tissue Sarcoma by MRI. Acad Radiol. 2017 05; 24(5):615-622.
Lee AY, Wisner DJ, Aminololama-Shakeri S, Arasu VA, Feig SA, Hargreaves J, Ojeda-Fournier H, Bassett LW, Wells CJ, De Guzman J, Flowers CI, Campbell JE, Elson SL, Retallack H, Joe BN. Inter-reader Variability in the Use of BI-RADS Descriptors for Suspicious Findings on Diagnostic Mammography: A Multi-institution Study of 10 Academic Radiologists. Acad Radiol. 2017 01; 24(1):60-66.
Lee AY, Elojeimy S, Kanal KM, Linnau KF, Gunn ML. The effect of trauma backboards on computed tomography radiation dose. Clin Radiol. 2016 May; 71(5):499.e1-8.
Lee AY, Ichikawa L, Lee JM, Lee CI, DeMartini WB, Joe BN, Wernli KJ, Sprague BL, Herschorn SD, Lehman CD. Concordance of BI-RADS Assessments and Management Recommendations for Breast MRI in Community Practice. AJR Am J Roentgenol. 2016 Jan; 206(1):211-6.
Ha AS, Lee AY, Hippe DS, Chou SH, Chew FS. Digital Tomosynthesis to Evaluate Fracture Healing: Prospective Comparison With Radiography and CT. AJR Am J Roentgenol. 2015 Jul; 205(1):136-41.
Rahbar H, DeMartini WB, Lee AY, Partridge SC, Peacock S, Lehman CD. Accuracy of 3 T versus 1.5 T breast MRI for pre-operative assessment of extent of disease in newly diagnosed DCIS. Eur J Radiol. 2015 Apr; 84(4):611-6.
Lehman CD, Lee AY, Lee CI. Imaging management of palpable breast abnormalities. AJR Am J Roentgenol. 2014 Nov; 203(5):1142-53.
Lee AY, Ha AS, Petscavage JM, Chew FS. Total ankle arthroplasty: a radiographic outcome study. AJR Am J Roentgenol. 2013 Jun; 200(6):1310-6.
Lee AY, Godwin JD, Pipavath SN. Case 182: pulmonary amyloidosis. Radiology. 2012 Jun; 263(3):929-32.
Lee AY, Poder L, Qayyum A, Wang ZJ, Yeh BM, Coakley FV. Imaging malignant and apparent malignant transformation of benign gynaecological disease. Clin Radiol. 2010 Dec; 65(12):1031-7.
Maira M, Long JE, Lee AY, Rubenstein JL, Stifani S. Erratum to: Role for TGF-β superfamily signaling in telencephalic GABAergic neuron development. J Neurodev Disord. 2010 Mar; 2(1):47.
Maira M, Long JE, Lee AY, Rubenstein JL, Stifani S. Role for TGF-beta superfamily signaling in telencephalic GABAergic neuron development. J Neurodev Disord. 2010 03; 2(1):48-60.
Lee AY, Raz DJ, He B, Jablons DM. Update on the molecular biology of malignant mesothelioma. Cancer. 2007 Apr 15; 109(8):1454-61.
Mazieres J, You L, He B, Xu Z, Twogood S, Lee AY, Reguart N, Batra S, Mikami I, Jablons DM. Wnt2 as a new therapeutic target in malignant pleural mesothelioma. Int J Cancer. 2005 Nov 01; 117(2):326-32.
Mazieres J, You L, He B, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM. Inhibition of Wnt16 in human acute lymphoblastoid leukemia cells containing the t(1;19) translocation induces apoptosis. Oncogene. 2005 Aug 11; 24(34):5396-400.
B. He, L. You, Z. Xu, A. Lee, N. Reguart, R. Rosell, D. Jablons. O-003 Writ inhibitory factor-1 (WIF-1) is silenced by promoter hypermethylation in human non-small cell lung cancer. Lung Cancer. 2005 Jul 1; 49:s5.
Mikami I, You L, He B, Xu Z, Batra S, Lee AY, Mazieres J, Reguart N, Uematsu K, Koizumi K, Jablons DM. Efficacy of Wnt-1 monoclonal antibody in sarcoma cells. BMC Cancer. 2005 May 24; 5:53.
He B, Reguart N, You L, Mazieres J, Xu Z, Lee AY, Mikami I, McCormick F, Jablons DM. Blockade of Wnt-1 signaling induces apoptosis in human colorectal cancer cells containing downstream mutations. Oncogene. 2005 Apr 21; 24(18):3054-8.
He B, Lee AY, Dadfarmay S, You L, Xu Z, Reguart N, Mazieres J, Mikami I, McCormick F, Jablons DM. Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cells. Cancer Res. 2005 Feb 01; 65(3):743-8.
Lee AY, He B, You L, Xu Z, Mazieres J, Reguart N, Mikami I, Batra S, Jablons DM. Dickkopf-1 antagonizes Wnt signaling independent of beta-catenin in human mesothelioma. Biochem Biophys Res Commun. 2004 Oct 29; 323(4):1246-50.
Reguart N, He B, Xu Z, You L, Lee AY, Mazieres J, Mikami I, Batra S, Rosell R, McCormick F, Jablons DM. Cloning and characterization of the promoter of human Wnt inhibitory factor-1. Biochem Biophys Res Commun. 2004 Oct 08; 323(1):229-34.
Lee AY, He B, You L, Dadfarmay S, Xu Z, Mazieres J, Mikami I, McCormick F, Jablons DM. Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma. Oncogene. 2004 Aug 26; 23(39):6672-6.
Mazieres J, He B, You L, Xu Z, Lee AY, Mikami I, Reguart N, Rosell R, McCormick F, Jablons DM. Wnt inhibitory factor-1 is silenced by promoter hypermethylation in human lung cancer. Cancer Res. 2004 Jul 15; 64(14):4717-20.
He B, You L, Xu Z, Mazieres J, Lee AY, Jablons DM. Activity of the suppressor of cytokine signaling-3 promoter in human non-small-cell lung cancer. Clin Lung Cancer. 2004 May; 5(6):366-70.
He B, You L, Uematsu K, Xu Z, Lee AY, Matsangou M, McCormick F, Jablons DM. A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells. Neoplasia. 2004 Jan-Feb; 6(1):7-14.
He B, You L, Uematsu K, Zang K, Xu Z, Lee AY, Costello JF, McCormick F, Jablons DM. SOCS-3 is frequently silenced by hypermethylation and suppresses cell growth in human lung cancer. Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24):14133-8.