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Molecular Garbage on Tumors Makes Easy Target for Antibody Drugs
Cancer’s rapid growth and messy waste disposal could mark it for destruction.
For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth and stayed hidden from the immune system.
But now researchers at UC San Francisco have discovered that the SRC enzyme also appears like a flag on the surface of bladder, colorectal, breast, pancreatic, and probably many other tumor cells.