Research Directions

Magnetic resonance (MR) is a robust noninvasive, nonionic imaging modality in biomedical investigations and clinical diagnosis, and is capable of capturing not only anatomic structure but also cellular and molecular information in living systems. The major problem of MR technology is its long acquisition time and low sensitivity, consequently resulting in limited temporal resolution and spatial resolution. Parallel imaging, compressed sensing, and ultrahigh field MR (7T and above) are promising MR methodologies, which are able to improve conventional MR performance in temporal resolution and spatial resolution in vivo. Our research focuses on development of ultrahigh field MR, parallel imaging and compressed sensing based fast imaging, and also integration of the two promising techniques, providing a fast, highly sensitive MR for in vivo biomedical research. The research endeavor involves parallel imaging algorithm, parallel excitation, compressed sensing, new strategies for high frequency RF coils and coil arrays, electromagnetic problems and computational electromagnetism in in-vivo MR at high fields by using FDTD method and other finite element methods, and applications of the developed techniques to in vivo MR Imaging and spectroscopy. Such applications include neuro imaging, neonatal/fetal imaging, extremity imaging, liver imaging, metabolic imaging, and the use of the hyperpolarized C-13 MR spectroscopic imaging to study metabolism and pathology in normal and cancerous conditions in humans and experimental animals. With increased capability of temporal resolution and spatial resolution, exploration of DTI with parallel imaging/compressed sensing technique at 7T is also an important research field in our group. Another research component in our group is miniature catheterized imaging and navigating devices and the software for endovascular imaging and treatment. Our research effort in advanced MR imaging also develop technologies facilitating the emerging precision medicine.

Research Resources

Surbeck Resources7T and 3T Whole-Body MRI at Mission Bay

Investigation of human disease and therapeutic interventions in brain, prostate, musculoskeletal, and neurological systems with dedicated support staff to assist users in application development.

 


7T MRI at China Basin

Anatomic imaging in rodents and small mammals with multi-parametric, multi-modality imaging capabilities, dynamic contrast enhancement imaging, experimental design services.

 


3T MRI at China Basin

Investigation of human disease and therapeutic interventions in brain, prostate, musculoskeletal, and neurological systems with dedicated support staff to assist users in application development.

 


Resonant Frequency CalculatorResonant Frequency Calculator

The Resonant Frequency Calculator can be used to compute resonant frequencies of a microstrip transmission line resonator with open/short ends or with termination capacitors.
 

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