Michael Ohliger, MD, PhD

Associate Professor
Modality Director for MRI
Associate Professor

Biography

Michael Ohliger, MD, PhD, is an Associate Professor in Residence in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. Dr. Ohliger obtained his PhD in Medical Physics from the Massachusetts Institute of Technology Harvard/MIT Division of Health Sciences and Technology in 2005, and he received his MD in Medicine from Harvard Medical School in 2007. He completed his residency in Diagnostic Radiology and fellowship training in Abdominal Imaging at UCSF. He joined the UCSF faculty in 2013.

Dr. Ohliger’s main research involves the development and clinical translation of new MRI techniques for the abdomen and pelvis, with a focus on molecular imaging of liver tumors, liver metabolism and liver injury. Current research projects involve using hyperpolarized carbon-13 MRI to image liver tumors as well as fatty liver disease. Dr. Ohliger also has a major research effort (together with Dr. David Wilson and Oren Rosenberg) developing novel methods for imaging bacterial injection.

Expertise:
Abdominal Imaging

Specialty:
Abdomen and pelvis

Professional Interests:
Cancer, abdominal imaging, genitourinary imaging, magnetic resonance imaging, physics, radiation, molecular imaging, hyperpolarized carbon, nuclear magnetic resonance, liver, kidney, prostate, bowel

Education and Training:
• Medical School: Harvard Medical School, Boston, Massachusetts - Medicine
• Internship: Brigham and Women’s Hospital, Boston, Massachusetts - Medicine
• Residency: University of California, San Francisco - Diagnostic Radiology
• Fellowship: University of California, San Francisco - Abdominal Imaging
• Doctor of Philosophy: Massachusetts Institute of Technology Harvard/MIT, Boston, Division of Health Sciences and Technology - Medical Physics
• California Physician and Surgeon License
• California X-ray Supervisor and Operator Certificate
• American Board of Radiology Certificate in Diagnostic Radiology

Education

Fellowship, 2013 - Abdominal Imaging, University of California, San Francisco
Residency, 2012 - Radiology, University of California, San Francisco
MD, 2007 - Medicine, Harvard Medical School
PhD, 2005 - Medical Physics, Massachusetts Institute of Technology

Honors and Awards

Research Scholar Award, Radiological Society of North America, 2014-2016
Cum Laude Award, Radiological Society of North America, 2011
Molecular Imaging Travel Award, Radiological Society of North America, 2011
Fleischner Research Award, Beth Israel Deaconess Medical Center Department of Radiology, Boston, MA, 2005

Publications

Ohliger MA. Hyperpolarized 13C Pyruvate MRI: An Important Window into Tumor Metabolism. Radiol Imaging Cancer. 2024 Mar; 6(2):e240004.
Alexandre M. Sorlin, Marina Lo´pez-A´lvarez, Jacob Biboy, Joe Gray, Sarah J. Rabbitt, Junaid Ur Rahim, Sang Hee Lee, Kondapa Naidu Bobba, Joseph Blecha, Mathew F.L. Parker, Robert R. Flavell, Joanne Engel, Michael Ohliger, Waldemar Vollmer, David M. Wilson. Peptidoglycan-Targeted [18F]3,3,3-Trifluoro-d-alanine Tracer for Imaging Bacterial Infection. JACS Au. 2024 Feb 25.
Agarwal S, Gordon J, Bok RA, von Morze C, Vigneron DB, Kurhanewicz J, Ohliger MA. Distinguishing metabolic signals of liver tumors from surrounding liver cells using hyperpolarized 13 C MRI and gadoxetate. Magn Reson Med. 2024 Jan 25.
Feuille C, Kari S, Patel R, Oberoi R, Liu J, Ohliger M, Khalili M, Tana M. Utility and impact of magnetic resonance elastography in the clinical course and management of chronic liver disease. Sci Rep. 2024 Jan 20; 14(1):1765.
Nickles TM, Kim Y, Lee PM, Chen HY, Ohliger M, Bok RA, Wang ZJ, Larson PEZ, Vigneron DB, Gordon JW. Hyperpolarized 13 C metabolic imaging of the human abdomen with spatiotemporal denoising. Magn Reson Med. 2024 Jan 09.
Piraquive Agudelo J, Kim Y, Agarwal S, Sriram R, Bok R, Kurhanewicz J, Mattis AN, Maher JJ, von Morze C, Ohliger MA. Hyperpolarized [1-13 C] pyruvate MRSI to detect metabolic changes in liver in a methionine and choline-deficient diet rat model of fatty liver disease. Magn Reson Med. 2024 Apr; 91(4):1625-1636.
Gordon JW, Chen HY, Nickles T, Lee PM, Bok R, Ohliger MA, Okamoto K, Ko AH, Larson PEZ, Wang ZJ. Hyperpolarized 13 C Metabolic MRI of Patients with Pancreatic Ductal Adenocarcinoma. J Magn Reson Imaging. 2023 Dec 02.
Hassan OT, Behr SC, Ohliger MA, Fowler KJ, Gill RM, Fidelman N, Mehta N, Choi HH. Per-patient Negative Predictive Value of the CT and MRI Liver Imaging Reporting and Data System Version 2018 Treatment Response Algorithm for Hepatocellular Carcinoma. Radiology. 2023 Dec; 309(3):e222776.
Lee SH, Kim JM, López-Álvarez M, Wang C, Sorlin AM, Bobba KN, Pichardo-González PA, Blecha J, Seo Y, Flavell RR, Engel J, Ohliger MA, Wilson DM. Imaging the Bacterial Cell Wall Using N-Acetyl Muramic Acid-Derived Positron Emission Tomography Radiotracers. ACS Sens. 2023 Dec 22; 8(12):4554-4565.
Parker MFL, López-Álvarez M, Alanizi AA, Luu JM, Polvoy I, Sorlin AM, Qin H, Lee S, Rabbitt SJ, Pichardo-González PA, Ordonez AA, Blecha J, Rosenberg OS, Flavell RR, Engel J, Jain SK, Ohliger MA, Wilson DM. Evaluating the Performance of Pathogen-Targeted Positron Emission Tomography Radiotracers in a Rat Model of Vertebral Discitis-Osteomyelitis. J Infect Dis. 2023 10 03; 228(Suppl 4):S281-S290.
Chen X, Gallagher F, Sellmyer MA, Ordonez AA, Kjaer A, Ohliger M, Wilson DM, Jain SK. Visualizing Bacterial Infections With Novel Targeted Molecular Imaging Approaches. J Infect Dis. 2023 10 03; 228(Suppl 4):S249-S258.
Sorlin AM, López-Álvarez M, Rabbitt SJ, Alanizi AA, Shuere R, Bobba KN, Blecha J, Sakhamuri S, Evans MJ, Bayles KW, Flavell RR, Rosenberg OS, Sriram R, Desmet T, Nidetzky B, Engel J, Ohliger MA, Fraser JS, Wilson DM. Chemoenzymatic Syntheses of Fluorine-18-Labeled Disaccharides from [18F] FDG Yield Potent Sensors of Living Bacteria In Vivo. J Am Chem Soc. 2023 08 16; 145(32):17632-17642.
Chattopadhyay A, Tully J, Shan J, Sheikh S, Ohliger M, Gordon JW, Mauro T, Abuabara K. Sodium in the skin: a summary of the physiology and a scoping review of disease associations. Clin Exp Dermatol. 2023 Jul 07; 48(7):733-743.
Hong CW, Chernyak V, Choi JY, Lee S, Potu C, Delgado T, Wolfson T, Gamst A, Birnbaum J, Kampalath R, Lall C, Lee JT, Owen JW, Aguirre DA, Mendiratta-Lala M, Davenport MS, Masch W, Roudenko A, Lewis SC, Kierans AS, Hecht EM, Bashir MR, Brancatelli G, Douek ML, Ohliger MA, Tang A, Cerny M, Fung A, Costa EA, Corwin MT, McGahan JP, Kalb B, Elsayes KM, Surabhi VR, Blair K, Marks RM, Horvat N, Best S, Ash R, Ganesan K, Kagay CR, Kambadakone A, Wang J, Cruite I, Bijan B, Goodwin M, Cunha GM, Tamayo-Murillo D, Fowler KJ, Sirlin CB. Erratum for: A Multicenter Assessment of Interreader Reliability of LI-RADS Version 2018 for MRI and CT. Radiology. 2023 Jul; 308(1):e239018.
Hong CW, Chernyak V, Choi JY, Lee S, Potu C, Delgado T, Wolfson T, Gamst A, Birnbaum J, Kampalath R, Lall C, Lee JT, Owen JW, Aguirre DA, Mendiratta-Lala M, Davenport MS, Masch W, Roudenko A, Lewis SC, Kierans AS, Hecht EM, Bashir MR, Brancatelli G, Douek ML, Ohliger MA, Tang A, Cerny M, Fung A, Costa EA, Corwin MT, McGahan JP, Kalb B, Elsayes KM, Surabhi VR, Blair K, Marks RM, Horvat N, Best S, Ash R, Ganesan K, Kagay CR, Kambadakone A, Wang J, Cruite I, Bijan B, Goodwin M, Moura Cunha G, Tamayo-Murillo D, Fowler KJ, Sirlin CB. A Multicenter Assessment of Interreader Reliability of LI-RADS Version 2018 for MRI and CT. Radiology. 2023 06; 307(5):e222855.
Guglielmo FF, Barr RG, Yokoo T, Ferraioli G, Lee JT, Dillman JR, Horowitz JM, Jhaveri KS, Miller FH, Modi RY, Mojtahed A, Ohliger MA, Pirasteh A, Reeder SB, Shanbhogue K, Silva AC, Smith EN, Surabhi VR, Taouli B, Welle CL, Yeh BM, Venkatesh SK. Liver Fibrosis, Fat, and Iron Evaluation with MRI and Fibrosis and Fat Evaluation with US: A Practical Guide for Radiologists. Radiographics. 2023 06; 43(6):e220181.
Sorlin AM, López-Álvarez M, Rabbitt SJ, Alanizi AA, Shuere R, Bobba KN, Blecha J, Sakhamuri S, Evans MJ, Bayles KW, Flavell RR, Rosenberg OS, Sriram R, Desmet T, Nidetzky B, Engel J, Ohliger MA, Fraser JS, Wilson DM. Chemoenzymatic syntheses of fluorine-18-labeled disaccharides from [ 18 F]FDG yield potent sensors of living bacteria in vivo. bioRxiv. 2023 May 20.
Shen W, Middleton MS, Cunha GM, Delgado TI, Wolfson T, Gamst A, Fowler KJ, Alazraki A, Trout AT, Ohliger MA, Shah SN, Bashir MR, Kleiner DE, Loomba R, Neuschwander-Tetri BA, Sanyal AJ, Zhou J, Sirlin CB, Lavine JE. Changes in abdominal adipose tissue depots assessed by MRI correlate with hepatic histologic improvement in non-alcoholic steatohepatitis. J Hepatol. 2023 02; 78(2):238-246.
Ohliger MA. Editorial for "Preoperative Assessment of MRI-Invisible Early-Stage Endometrial Cancer With MRI-Based Radiomics Analysis". J Magn Reson Imaging. 2023 Jul; 58(1):256-257.
David Wilson, Anju Anju, Matthew Parker, Niranjan Meher, Joseph Blecha, Oren Rosenberg, Michael Ohliger, Robert Flavell. P-65 Cyclic [68Ga] and [18F]AlF-labeled peptides for specific detection of human angiotensin-converting enzyme 2. Nuclear Medicine and Biology. 2022 Nov 1; 114:s64-s65.
Ohliger MA. Body Composition at CT and Risk of Future Disease. Radiology. 2023 Feb; 306(2):e222162.
Chen HY, Bok RA, Cooperberg MR, Nguyen HG, Shinohara K, Westphalen AC, Wang ZJ, Ohliger MA, Gebrezgiabhier D, Carvajal L, Gordon JW, Larson PEZ, Aggarwal R, Kurhanewicz J, Vigneron DB. Improving multiparametric MR-transrectal ultrasound guided fusion prostate biopsies with hyperpolarized 13 C pyruvate metabolic imaging: A technical development study. Magn Reson Med. 2022 Dec; 88(6):2609-2620.
Ilona Polvoy, Robert R. Flavell, Oren S. Rosenberg, Michael A. Ohliger, David M. Wilson. Nuclear imaging of bacterial infection: the state of the art and future directions. Chinese Journal of Nuclear Medicine and Molecular Imaging. 2022 Jul 25; 42(07):436-444.
Keshav N, Ohliger MA. Imaging Vascular Disorders of the Liver. Radiol Clin North Am. 2022 Sep; 60(5):857-871.
Polvoy I, Seo Y, Parker M, Stewart M, Siddiqua K, Manacsa HS, Ravanfar V, Blecha J, Hope TA, Vanbrocklin H, Flavell RR, Barry J, Hansen E, Villanueva-Meyer JE, Engel J, Rosenberg OS, Wilson DM, Ohliger MA. Imaging joint infections using D-methyl-11C-methionine PET/MRI: initial experience in humans. Eur J Nucl Med Mol Imaging. 2022 09; 49(11):3761-3771.
Lee PM, Chen HY, Gordon JW, Wang ZJ, Bok R, Hashoian R, Kim Y, Liu X, Nickles T, Cheung K, Alas FL, Daniel H, Larson PEZ, von Morze C, Vigneron DB, Ohliger MA. Whole-Abdomen Metabolic Imaging of Healthy Volunteers Using Hyperpolarized [1-13 C]pyruvate MRI. J Magn Reson Imaging. 2022 12; 56(6):1792-1806.
Ohliger MA. Invited Commentary: MRI Radiofrequency Coils-Current Uses and Future Innovation. Radiographics. 2022 May-Jun; 42(3):E100-E101.
Zhang PP, Choi HH, Ohliger MA. Detection of fatty liver using virtual non-contrast dual-energy CT. Abdom Radiol (NY). 2022 06; 47(6):2046-2056.
Ye Z, Song B, Lee PM, Ohliger MA, Laustsen C. Hyperpolarized carbon 13 MRI in liver diseases: Recent advances and future opportunities. Liver Int. 2022 05; 42(5):973-983.
Chen JV, Ohliger MA, Chung M, Sugi MD, Ye J, Nishimura SL, Choi HH. Diagnosis of acute mesenteric ischemia assisted by dual-energy CT: a case report. Emerg Radiol. 2022 Jun; 29(3):611-614.
de Kouchkovsky I, Chen HY, Ohliger MA, Wang ZJ, Bok RA, Gordon JW, Larson PEZ, Frost M, Okamoto K, Cooperberg MR, Kurhanewicz J, Vigneron DB, Aggarwal R. Hyperpolarized 1-[13C]-Pyruvate Magnetic Resonance Imaging Detects an Early Metabolic Response to Immune Checkpoint Inhibitor Therapy in Prostate Cancer. Eur Urol. 2022 02; 81(2):219-221.
Polvoy I, Qin H, Flavell RR, Gordon J, Viswanath P, Sriram R, Ohliger MA, Wilson DM. Deuterium Metabolic Imaging-Rediscovery of a Spectroscopic Tool. Metabolites. 2021 Aug 25; 11(9).
Obmann MM, Sun Y, An C, Ohliger MA, Wang ZJ, Yeh BM. Bowel Peristalsis Artifact on Dual-Energy CT: In Vitro Study on the Influence of Different Dual-Energy CT Platforms and Enteric Contrast Agents. AJR Am J Roentgenol. 2022 02; 218(2):290-299.
Ohliger MA. Quantitative Dual-Energy CT and Crohn Disease. Radiology. 2021 10; 301(1):152-153.
Lee PM, Chen HY, Gordon JW, Zhu Z, Larson PEZ, Dwork N, Van Criekinge M, Carvajal L, Ohliger MA, Wang ZJ, Xu D, Kurhanewicz J, Bok RA, Aggarwal R, Munster PN, Vigneron DB. Specialized computational methods for denoising, B1 correction, and kinetic modeling in hyperpolarized 13 C MR EPSI studies of liver tumors. Magn Reson Med. 2021 11; 86(5):2402-2411.
Hetts SW, Shieh JT, Ohliger MA, Conrad MB. Hereditary Hemorrhagic Telangiectasia: The Convergence of Genotype, Phenotype, and Imaging in Modern Diagnosis and Management of a Multisystem Disease. Radiology. 2021 07; 300(1):17-30.
Zhang TT, Chang WC, Wang ZJ, Sun DC, Ohliger MA, Yeh BM. Bowel Wall Visualization Using MR Enterography in Relationship to Bowel Lumen Contents and Patient Demographics. J Magn Reson Imaging. 2021 09; 54(3):728-736.
Parker MFL, Blecha J, Rosenberg O, Ohliger M, Flavell RR, Wilson DM. Cyclic 68Ga-Labeled Peptides for Specific Detection of Human Angiotensin-Converting Enzyme 2. J Nucl Med. 2021 11; 62(11):1631-1637.
Cornelius von Morze, Michael A. Ohliger. 10 Integration of Hyperpolarized 13C MRI into Liver Studies. . 2021 Jan 1; 3:257-272.
von Morze C, Reed GD, Wang ZJ, Ohliger MA, Laustsen C. Hyperpolarized Carbon (13C) MRI of the Kidneys: Basic Concept. Methods Mol Biol. 2021; 2216:267-278.
Harwin J, Sugi MD, Hetts SW, Conrad MB, Ohliger MA. The Role of Liver Imaging in Hereditary Hemorrhagic Telangiectasia. J Clin Med. 2020 Nov 21; 9(11).
Tana MM, McCoy D, Lee B, Patel R, Lin J, Ohliger MA. Texture features from computed tomography correlate with markers of severity in acute alcohol-associated hepatitis. Sci Rep. 2020 10 21; 10(1):17980.
Polvoy I, Flavell RR, Rosenberg OS, Ohliger MA, Wilson DM. Nuclear Imaging of Bacterial Infection: The State of the Art and Future Directions. J Nucl Med. 2020 12; 61(12):1708-1716.
Ohliger MA, Gordon JW, Carvajal L, Larson PEZ, Ou JJ, Agarwal S, Zhu Z, Vigneron DB, von Morze C. 55 Mn-based fiducial markers for rapid and automated RF coil localization for hyperpolarized 13 C MRI. Magn Reson Med. 2021 01; 85(1):518-530.
Ullrich T, Kohli MD, Ohliger MA, Magudia K, Arora SS, Barrett T, Bittencourt LK, Margolis DJ, Schimmöller L, Turkbey B, Westphalen AC. Quality Comparison of 3 Tesla multiparametric MRI of the prostate using a flexible surface receiver coil versus conventional surface coil plus endorectal coil setup. Abdom Radiol (NY). 2020 12; 45(12):4260-4270.
Chang AY, Sun DC, Ohliger MA, Abuzahriyeh T, Choi HH. Boba sign: a novel sign for floating balls within a mature cystic teratoma. Abdom Radiol (NY). 2020 09; 45(9):2931-2933.
Parker MFL, Flavell RR, Luu JM, Rosenberg OS, Ohliger MA, Wilson DM. Small Molecule Sensors Targeting the Bacterial Cell Wall. ACS Infect Dis. 2020 07 10; 6(7):1587-1598.
Kalita M, Parker MFL, Luu JM, Stewart MN, Blecha JE, VanBrocklin HF, Evans MJ, Flavell RR, Rosenberg OS, Ohliger MA, Wilson DM. Arabinofuranose-derived positron-emission tomography radiotracers for detection of pathogenic microorganisms. J Labelled Comp Radiopharm. 2020 05 15; 63(5):231-239.
Jha P, Masselli G, Ohliger MA, Poder L. Nonfetal Imaging During Pregnancy: Placental Disease. Radiol Clin North Am. 2020 Mar; 58(2):381-399.
Parker MFL, Luu JM, Schulte B, Huynh TL, Stewart MN, Sriram R, Yu MA, Jivan S, Turnbaugh PJ, Flavell RR, Rosenberg OS, Ohliger MA, Wilson DM. Sensing Living Bacteria in Vivo Using d-Alanine-Derived 11C Radiotracers. ACS Cent Sci. 2020 Feb 26; 6(2):155-165.
Ohliger MA, Choi HH, Coutier J. Imaging Safety and Technical Considerations in the Reproductive Age Female. Radiol Clin North Am. 2020 Mar; 58(2):199-213.
Stewart MN, Parker MFL, Jivan S, Luu JM, Huynh TL, Schulte B, Seo Y, Blecha JE, Villanueva-Meyer JE, Flavell RR, VanBrocklin HF, Ohliger MA, Rosenberg O, Wilson DM. High Enantiomeric Excess In-Loop Synthesis of d-[methyl-11C]Methionine for Use as a Diagnostic Positron Emission Tomography Radiotracer in Bacterial Infection. ACS Infect Dis. 2020 01 10; 6(1):43-49.
Chen HY, Aggarwal R, Bok RA, Ohliger MA, Zhu Z, Lee P, Gordon JW, van Criekinge M, Carvajal L, Slater JB, Larson PEZ, Small EJ, Kurhanewicz J, Vigneron DB. Hyperpolarized 13C-pyruvate MRI detects real-time metabolic flux in prostate cancer metastases to bone and liver: a clinical feasibility study. Prostate Cancer Prostatic Dis. 2020 06; 23(2):269-276.
Jha P, Rabban J, Chen LM, Goldstein RB, Weinstein S, Morgan TA, Shum D, Hills N, Ohliger MA, Poder L. Placenta accreta spectrum: value of placental bulge as a sign of myometrial invasion on MR imaging. Abdom Radiol (NY). 2019 07; 44(7):2572-2581.
Wang ZJ, Ohliger MA, Larson PEZ, Gordon JW, Bok RA, Slater J, Villanueva-Meyer JE, Hess CP, Kurhanewicz J, Vigneron DB. Hyperpolarized 13C MRI: State of the Art and Future Directions. Radiology. 2019 05; 291(2):273-284.
Zhu Z, Zhu X, Ohliger MA, Tang S, Cao P, Carvajal L, Autry AW, Li Y, Kurhanewicz J, Chang S, Aggarwal R, Munster P, Xu D, Larson PEZ, Vigneron DB, Gordon JW. Coil combination methods for multi-channel hyperpolarized 13C imaging data from human studies. J Magn Reson. 2019 04; 301:73-79.
Ohliger MA, Westphalen AC. Overcoming the challenges of imaging patients with metabolic syndrome. Radiol Bras. 2019 Jan-Feb; 52(1):V-VI.
Movilla P, Ohliger M, Wood S. Prepared for the Unexpected: Accessory Ovaries with Abernethy Malformation. J Minim Invasive Gynecol. 2019 Jul - Aug; 26(5):977-980.
Bashir MR, Wolfson T, Gamst AC, Fowler KJ, Ohliger M, Shah SN, Alazraki A, Trout AT, Behling C, Allende DS, Loomba R, Sanyal A, Schwimmer J, Lavine JE, Shen W, Tonascia J, Van Natta ML, Mamidipalli A, Hooker J, Kowdley KV, Middleton MS, Sirlin CB, NASH Clinical Research Network (NASH CRN). Hepatic R2* is more strongly associated with proton density fat fraction than histologic liver iron scores in patients with nonalcoholic fatty liver disease. J Magn Reson Imaging. 2019 05; 49(5):1456-1466.
Yeh BM, Obmann MM, Westphalen AC, Ohliger MA, Yee J, Sun Y, Wang ZJ. Dual Energy Computed Tomography Scans of the Bowel: Benefits, Pitfalls, and Future Directions. Radiol Clin North Am. 2018 Sep; 56(5):805-819.
Bailey JJ, Jordan EJ, Burke C, Ohliger MA, Wang ZJ, Van Loon K, Varma MG, Hope TA. Does Extended PET Acquisition in PET/MRI Rectal Cancer Staging Improve Results? AJR Am J Roentgenol. 2018 10; 211(4):896-900.
Wang ZJ, Behr S, Consunji MV, Yeh BM, Ohliger MA, Gao K, Ko AH, Cinar P, Tempero MA, Collisson EA. Early Response Assessment in Pancreatic Ductal Adenocarcinoma Through Integrated PET/MRI. AJR Am J Roentgenol. 2018 11; 211(5):1010-1019.
Rahul Raj Aggarwal, Zihan Zhu, Michael Ohliger, Jeremy Gordon, Robert A. Bok, Jim Slater, John V. Kurhanewicz, Emily Boyd, Susan Calabrese, Christopher E. Sotto, Daniel B. Vigneron, Pamela N. Munster. Hyperpolarized C-13 pyuvate metabolic MR imaging of solid tumor liver metastases as a biomarker of PI3K/mTOR pathway activity. Journal of Clinical Oncology. 2018 May 20; 36(15_suppl):e24168-e24168.
Mutch CA, Ordonez AA, Qin H, Parker M, Bambarger LE, Villanueva-Meyer JE, Blecha J, Carroll V, Taglang C, Flavell R, Sriram R, VanBrocklin H, Rosenberg O, Ohliger MA, Jain SK, Neumann KD, Wilson DM. [11C]Para-Aminobenzoic Acid: A Positron Emission Tomography Tracer Targeting Bacteria-Specific Metabolism. ACS Infect Dis. 2018 07 13; 4(7):1067-1072.
Roshan Patel, Rohan Oberoi, Mandana Khalili, Michael A. Ohliger, Michele Tana. Tu1545 - The Utility of Mr Elastography in Hepatology Practice: Perspectives from a Safety Net Hospital. Gastroenterology. 2018 May 1; 154(6):s-1246-s-1247.
Hicks RM, Loening AM, Ohliger MA, Vasanawala SS, Hope TA. Variable refocusing flip angle single-shot fast spin echo imaging of liver lesions: increased speed and lesion contrast. Abdom Radiol (NY). 2018 03; 43(3):593-599.
von Morze C, Reed GD, Larson PE, Mammoli D, Chen AP, Tropp J, Van Criekinge M, Ohliger MA, Kurhanewicz J, Vigneron DB, Merritt ME. In vivo hyperpolarization transfer in a clinical MRI scanner. Magn Reson Med. 2018 08; 80(2):480-487.
Sriram R, Sun J, Villanueva-Meyer J, Mutch C, De Los Santos J, Peters J, Korenchan DE, Neumann K, Van Criekinge M, Kurhanewicz J, Rosenberg O, Wilson D, Ohliger MA. Detection of Bacteria-Specific Metabolism Using Hyperpolarized [2-13C]Pyruvate. ACS Infect Dis. 2018 05 11; 4(5):797-805.
Morze CV, Allu PKR, Chang GY, Marco-Rius I, Milshteyn E, Wang ZJ, Ohliger MA, Gleason CE, Kurhanewicz J, Vigneron DB, Pearce D. Non-invasive detection of divergent metabolic signals in insulin deficiency vs. insulin resistance in vivo. Sci Rep. 2018 02 01; 8(1):2088.
von Morze C, Ohliger MA, Marco-Rius I, Wilson DM, Flavell RR, Pearce D, Vigneron DB, Kurhanewicz J, Wang ZJ. Direct assessment of renal mitochondrial redox state using hyperpolarized 13 C-acetoacetate. Magn Reson Med. 2018 04; 79(4):1862-1869.
David Wilson, Michael Ohliger. Introduction: MRI/MRS as Metabolic Imaging Tools. Imaging and Metabolism. 2018 Jan 1; 81-98.
Baghdanian AH, Baghdanian AA, Puppala S, Tana M, Ohliger MA. Imaging Manifestations of Peptic Ulcer Disease on Computed Tomography. Semin Ultrasound CT MR. 2018 Apr; 39(2):183-192.
von Morze C, Tropp J, Chen AP, Marco-Rius I, Van Criekinge M, Skloss TW, Mammoli D, Kurhanewicz J, Vigneron DB, Ohliger MA, Merritt ME. Sensitivity enhancement for detection of hyperpolarized 13 C MRI probes with 1 H spin coupling introduced by enzymatic transformation in vivo. Magn Reson Med. 2018 07; 80(1):36-41.
Tang A, Bashir MR, Corwin MT, Cruite I, Dietrich CF, Do RKG, Ehman EC, Fowler KJ, Hussain HK, Jha RC, Karam AR, Mamidipalli A, Marks RM, Mitchell DG, Morgan TA, Ohliger MA, Shah A, Vu KN, Sirlin CB, LI-RADS Evidence Working Group. Evidence Supporting LI-RADS Major Features for CT- and MR Imaging-based Diagnosis of Hepatocellular Carcinoma: A Systematic Review. Radiology. 2018 01; 286(1):29-48.
Neumann KD, Villanueva-Meyer JE, Mutch CA, Flavell RR, Blecha JE, Kwak T, Sriram R, VanBrocklin HF, Rosenberg OS, Ohliger MA, Wilson DM. Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers. Sci Rep. 2017 08 11; 7(1):7903.
Horowitz JM, Venkatesh SK, Ehman RL, Jhaveri K, Kamath P, Ohliger MA, Samir AE, Silva AC, Taouli B, Torbenson MS, Wells ML, Yeh B, Miller FH. Evaluation of hepatic fibrosis: a review from the society of abdominal radiology disease focus panel. Abdom Radiol (NY). 2017 08; 42(8):2037-2053.
Leelakanok N, Phelps AS, Zapala MA, Kato K, Ohliger M, Li Y, Courtier J. Assessing 3D T2 FSE sequence for identification of the normal appendix: working toward a single-sequence MR appendicitis protocol. Emerg Radiol. 2017 Dec; 24(6):653-660.
Ohliger MA, Hope TA, Chapman JS, Chen LM, Behr SC, Poder L. PET/MR Imaging in Gynecologic Oncology. Magn Reson Imaging Clin N Am. 2017 Aug; 25(3):667-684.
Wilson DM, Di Gialleonardo V, Wang ZJ, Carroll V, Von Morze C, Taylor A, Sai V, VanCriekinge M, Bok R, Ohliger MA, Keshari KR. Hyperpolarized 13C Spectroscopic Evaluation of Oxidative Stress in a Rodent Model of Steatohepatitis. Sci Rep. 2017 04 20; 7:46014.
Marco-Rius I, Gordon JW, Mattis AN, Bok R, Delos Santos R, Sukumar S, Larson PEZ, Vigneron DB, Ohliger MA. Diffusion-weighted imaging of hyperpolarized [13 C]urea in mouse liver. J Magn Reson Imaging. 2018 01; 47(1):141-151.
Lambert JW, Sun Y, Gould RG, Ohliger MA, Li Z, Yeh BM. An Image-Domain Contrast Material Extraction Method for Dual-Energy Computed Tomography. Invest Radiol. 2017 04; 52(4):245-254.
Dotson B, Lambert JW, Wang ZJ, Sun Y, Ohliger MA, Winklhofer S, Yeh BM. Benefit of iodine density images to reduce out-of-field image artifacts at rapid kVp switching dual-energy CT. Abdom Radiol (NY). 2017 03; 42(3):735-741.
Marco-Rius I, von Morze C, Sriram R, Cao P, Chang GY, Milshteyn E, Bok RA, Ohliger MA, Pearce D, Kurhanewicz J, Larson PE, Vigneron DB, Merritt M. Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2-13 C]dihydroxyacetone. Magn Reson Med. 2017 01; 77(1):65-73.
Ehman EC, Umetsu SE, Ohliger MA, Fidelman N, Ferrell LD, Yeh BM, Yee J, Hope TA. Imaging prediction of residual hepatocellular carcinoma after locoregional therapy in patients undergoing liver transplantation or partial hepatectomy. Abdom Radiol (NY). 2016 11; 41(11):2161-2168.
Shang H, Sukumar S, von Morze C, Bok RA, Marco-Rius I, Kerr A, Reed GD, Milshteyn E, Ohliger MA, Kurhanewicz J, Larson PEZ, Pauly JM, Vigneron DB. Spectrally selective three-dimensional dynamic balanced steady-state free precession for hyperpolarized C-13 metabolic imaging with spectrally selective radiofrequency pulses. Magn Reson Med. 2017 09; 78(3):963-975.
Gordon JW, Milshteyn E, Marco-Rius I, Ohliger M, Vigneron DB, Larson PEZ. Mis-estimation and bias of hyperpolarized apparent diffusion coefficient measurements due to slice profile effects. Magn Reson Med. 2017 09; 78(3):1087-1092.
Ehman EC, Phelps AS, Ohliger MA, Rhee SJ, MacKenzie JD, Courtier JL. Detection of bowel inflammation with fused DWI/T2 images versus contrast-enhanced images in pediatric MR enterography with histopathologic correlation. Clin Imaging. 2016 Nov - Dec; 40(6):1135-1139.
Ohliger MA, von Morze C, Marco-Rius I, Gordon J, Larson PEZ, Bok R, Chen HY, Kurhanewicz J, Vigneron D. Combining hyperpolarized 13 C MRI with a liver-specific gadolinium contrast agent for selective assessment of hepatocyte metabolism. Magn Reson Med. 2017 06; 77(6):2356-2363.
E. Collisson, M. Ohliger, B. Yeh, D. Kelly, M. Pampaloni, A. Ko, M. Tempero, Z. Wang. P-221PET-MR Imaging to Assess early treatment response in Pancreatic Adenocarcinoma. Annals of Oncology. 2016 Jun 1; 27(suppl 2):ii64.2-ii64.
Cornelius von Morze, Robert A. Bok, Michael A. Ohliger, Zihan Zhu, Daniel B. Vigneron, John Kurhanewicz. Hyperpolarized [13C]ketobutyrate, a molecular analog of pyruvate with modified specificity for LDH isoforms. Magnetic Resonance in Medicine. 2016 May 1; 75(5):spcone-spcone.
Hicks RM, Yee J, Ohliger MA, Weinstein S, Kao J, Ikram NS, Hope TA. Comparison of diffusion-weighted imaging and T2-weighted single shot fast spin-echo: Implications for LI-RADS characterization of hepatocellular carcinoma. Magn Reson Imaging. 2016 Sep; 34(7):915-21.
Marco-Rius I, Cao P, von Morze C, Merritt M, Moreno KX, Chang GY, Ohliger MA, Pearce D, Kurhanewicz J, Larson PE, Vigneron DB. Multiband spectral-spatial RF excitation for hyperpolarized [2-13 C]dihydroxyacetone 13 C-MR metabolism studies. Magn Reson Med. 2017 04; 77(4):1419-1428.
Shang H, Larson PEZ, Kerr A, Reed G, Sukumar S, Elkhaled A, Gordon JW, Ohliger MA, Pauly JM, Lustig M, Vigneron DB. Multiband RF pulses with improved performance via convex optimization. J Magn Reson. 2016 Jan; 262:81-90.
Shital Gandhi, Michael Ohliger, Liina Poder. State-of-the-Art Imaging of the Placenta. Current Radiology Reports. 2015 Dec 1; 3(12):46.
Feng Y, Gordon JW, Shin PJ, von Morze C, Lustig M, Larson PEZ, Ohliger MA, Carvajal L, Tropp J, Pauly JM, Vigneron DB. Development and testing of hyperpolarized (13)C MR calibrationless parallel imaging. J Magn Reson. 2016 Jan; 262:1-7.
Hope TA, Verdin EF, Bergsland EK, Ohliger MA, Corvera CU, Nakakura EK. Correcting for respiratory motion in liver PET/MRI: preliminary evaluation of the utility of bellows and navigated hepatobiliary phase imaging. EJNMMI Phys. 2015 Dec; 2(1):21.
Lee SA, Plett SK, Luetkemeyer AF, Borgo GM, Ohliger MA, Conrad MB, Cookson BT, Sengupta DJ, Koehler JE. Bartonella quintana Aortitis in a Man with AIDS, Diagnosed by Needle Biopsy and 16S rRNA Gene Amplification. J Clin Microbiol. 2015 Aug; 53(8):2773-6.
von Morze C, Bok RA, Ohliger MA, Zhu Z, Vigneron DB, Kurhanewicz J. Hyperpolarized [(13)C]ketobutyrate, a molecular analog of pyruvate with modified specificity for LDH isoforms. Magn Reson Med. 2016 May; 75(5):1894-900.
Shin PJ, Larson PE, Uecker M, Reed GD, Kerr AB, Tropp J, Ohliger MA, Nelson SJ, Pauly JM, Lustig M, Vigneron DB. Chemical shift separation with controlled aliasing for hyperpolarized (13) C metabolic imaging. Magn Reson Med. 2015 Oct; 74(4):978-89.
Hope TA, Ohliger MA, Qayyum A. MR imaging of diffuse liver disease: from technique to diagnosis. Radiol Clin North Am. 2014 Jul; 52(4):709-24.
Shin PJ, Larson PE, Ohliger MA, Elad M, Pauly JM, Vigneron DB, Lustig M. Calibrationless parallel imaging reconstruction based on structured low-rank matrix completion. Magn Reson Med. 2014 Oct; 72(4):959-70.
Courtier J, Ohliger M, Rhee SJ, Terreblanche O, Heyman MB, MacKenzie JD. Shooting a moving target: use of real-time cine magnetic resonance imaging in assessment of the small bowel. J Pediatr Gastroenterol Nutr. 2013 Oct; 57(4):426-31.
Ohliger MA, Larson PE, Bok RA, Shin P, Hu S, Tropp J, Robb F, Carvajal L, Nelson SJ, Kurhanewicz J, Vigneron DB. Combined parallel and partial fourier MR reconstruction for accelerated 8-channel hyperpolarized carbon-13 in vivo magnetic resonance Spectroscopic imaging (MRSI). J Magn Reson Imaging. 2013 Sep; 38(3):701-13.
Daniel K. Sodickson, Michael A. Ohliger, Riccardo Lattanzi, Graham C. Wiggins. Coil Array Design for Parallel Imaging: Theory and Applications. Encyclopedia of Magnetic Resonance. 2011 Dec 15.
Lattanzi R, Grant AK, Polimeni JR, Ohliger MA, Wiggins GC, Wald LL, Sodickson DK. Performance evaluation of a 32-element head array with respect to the ultimate intrinsic SNR. NMR Biomed. 2010 Feb; 23(2):142-51.
Ohliger MA, Sodickson DK. An introduction to coil array design for parallel MRI. NMR Biomed. 2006 May; 19(3):300-15.
Ohliger MA, Greenman RL, Giaquinto R, McKenzie CA, Wiggins G, Sodickson DK. Concentric coil arrays for parallel MRI. Magn Reson Med. 2005 Nov; 54(5):1248-60.
Willig-Onwuachi JD, Yeh EN, Grant AK, Ohliger MA, McKenzie CA, Sodickson DK. Phase-constrained parallel MR image reconstruction. J Magn Reson. 2005 Oct; 176(2):187-98.
Yeh EN, Stuber M, McKenzie CA, Botnar RM, Leiner T, Ohliger MA, Grant AK, Willig-Onwuachi JD, Sodickson DK. Inherently self-calibrating non-Cartesian parallel imaging. Magn Reson Med. 2005 Jul; 54(1):1-8.
Yeh EN, McKenzie CA, Ohliger MA, Sodickson DK. Parallel magnetic resonance imaging with adaptive radius in k-space (PARS): constrained image reconstruction using k-space locality in radiofrequency coil encoded data. Magn Reson Med. 2005 Jun; 53(6):1383-92.
Sodickson DK, Hardy CJ, Zhu Y, Giaquinto RO, Gross P, Kenwood G, Niendorf T, Lejay H, McKenzie CA, Ohliger MA, Grant AK, Rofsky NM. Rapid volumetric MRI using parallel imaging with order-of-magnitude accelerations and a 32-element RF coil array: feasibility and implications. Acad Radiol. 2005 May; 12(5):626-35.
Zhu Y, Hardy CJ, Sodickson DK, Giaquinto RO, Dumoulin CL, Kenwood G, Niendorf T, Lejay H, McKenzie CA, Ohliger MA, Rofsky NM. Highly parallel volumetric imaging with a 32-element RF coil array. Magn Reson Med. 2004 Oct; 52(4):869-77.
Ohliger MA, Ledden P, McKenzie CA, Sodickson DK. Effects of inductive coupling on parallel MR image reconstructions. Magn Reson Med. 2004 Sep; 52(3):628-39.
Ohliger MA, Grant AK, Sodickson DK. Ultimate intrinsic signal-to-noise ratio for parallel MRI: electromagnetic field considerations. Magn Reson Med. 2003 Nov; 50(5):1018-30.
McKenzie CA, Yeh EN, Ohliger MA, Price MD, Sodickson DK. Self-calibrating parallel imaging with automatic coil sensitivity extraction. Magn Reson Med. 2002 Mar; 47(3):529-38.
Daniel K. Sodickson, Charles A. McKenzie, Michael A. Ohliger, Ernest N. Yeh, Mark D. Price. Recent advances in image reconstruction, coil sensitivity calibration, and coil array design for SMASH and generalized parallel MRI. Magnetic Resonance Materials in Physics, Biology and Medicine. 2002 Jan 1; 13(3):158-163.
Sodickson DK, McKenzie CA, Ohliger MA, Yeh EN, Price MD. Recent advances in image reconstruction, coil sensitivity calibration, and coil array design for SMASH and generalized parallel MRI. MAGMA. 2002 Jan; 13(3):158-63.
McKenzie CA, Ohliger MA, Yeh EN, Price MD, Sodickson DK. Coil-by-coil image reconstruction with SMASH. Magn Reson Med. 2001 Sep; 46(3):619-23.
Foster MH, Kieber-Emmons T, Ohliger M, Madaio MP. Molecular and structural analysis of nuclear localizing anti-DNA lupus antibodies. Immunol Res. 1994; 13(2-3):186-206.