Michael Hope, MD

Associate Professor
Assoc. Professor in Residence

Biography

Michael D. Hope, MD, is an Associate Professor in Residence in the Department of Radiology at UCSF. He obtained his medical degree from Stanford in 2004. The following year, he did a Medicine internship at California Pacific Medical Center. Dr. Hope completed his Diagnostic Radiology residency at UCSF in 2009, followed by a fellowship in Cardiopulmonary Imaging. He is the Co-Director of the Vascular Imaging Research Center at UCSF, Chair of the MR Safety Committee, and increasingly recognized as an expert in advanced cardiovascular imaging techniques with over 60 invited lectures and 75 peer-reviewed papers, which have been cited over 1,900 times.

Dr. Hope was recently awarded an R01 grant entitled, "Hemodynamic and inflammatory imaging in evaluation of abdominal aortic aneurysms" (R01HL123759). His long-term goal is to expand significantly the role of MR vessel and blood flow imaging in the clinical management of patients with cardiovascular disease.

Expertise:
Cardiac, Aortic and Pulmonary Imaging

Specialty:
Advanced Aortic Imaging
4D Flow Vascular Imaging

Professional Interests:
MR vessel wall and blood flow imaging in the clinical management of patients with cardiovascular disease

Education and Training:
• Medical School: Stanford University School of Medicine, California
• Internship: California Pacific Medical Center, San Francisco
• Residency: University of California, San Francisco
• Fellowship: University of California, San Francisco - Cardiopulmonary Imaging
• California Medical License
• American Board of Radiology, Certificate in Diagnostic Radiology

Education

Fellowship, 2010 - Cardiopulmonary Imaging, University of California, San Francisco
Residency, 2009 - Radiology, University of California, San Francisco
M.D., 2004 - School of Medicine, Stanford University

Honors and Awards

Charles A. Dobry Visiting Professor, University of Nebraska Medical Center, 2017
Outstanding Teacher Award, International Society for Magnetic Resonance in Medicine (ISMRM), 2017
R01 Grant, NIH/NHLBI, 2015
Excellence in Teaching Award, Haile T. Debas Academy of Medical Educators, UCSF, 2015
Distinguished Reviewer, Magnetic Resonance in Medicine, 2013
Research Scholar Grant, Radiological Society of North America (RSNA), 2012
1st Prize Young Investigator Award, North American Society for Cardiovascular Imaging (NASCI), 2009
Resident Research Grant, Radiological Society of North America (RSNA), 2008
1st Prize Bayer Poster Competition, North American Society for Cardiovascular Imaging (NASCI), 2008
Lauterbur Award Young Investigator Research Abstract Awards, Society of Computeed Body Tomography and Magnetic Resonance (SCBT/MR), 2004

Publications

Zhu C, Haraldsson H, Kallianos K, Ge L, Tseng E, Henry T, Saloner D, Hope MD. Gated thoracic magnetic resonance angiography at 3T: noncontrast versus blood pool contrast. Int J Cardiovasc Imaging. 2017 Sep 13.
Mukai K, Burris NS, Mahadevan VS, Foster ED, Ordovas KG, Hope MD. 4D flow image quality with blood pool contrast: a comparison of gadofosveset trisodium and ferumoxytol. Int J Cardiovasc Imaging. 2017 Sep 08.
Burris NS, Hope MD. Evolving treatment options for valve and aortic disease with bicuspid aortic valve. Ann Transl Med. 2017 Aug; 5(16):333.
Wang Y, Seguro F, Kao E, Zhang Y, Faraji F, Zhu C, Haraldsson H, Hope M, Saloner D, Liu J. Segmentation of lumen and outer wall of abdominal aortic aneurysms from 3D black-blood MRI with a registration based geodesic active contour model. Med Image Anal. 2017 Aug; 40:1-10.
Villanueva-Meyer JE, Naeger DM, Courtier JL, Hope MD, Lambert JW, MacKenzie JD, Phelps AS. Pediatric chest CT at chest radiograph doses: when is the ultralow-dose chest CT clinically appropriate? Emerg Radiol. 2017 Aug; 24(4):369-376.
Kallianos K, Henry TS, Yeghiazarians Y, Zimmet J, Shunk KA, Tseng EE, Mahadevan V, Hope MD. Ferumoxytol MRA for transcatheter aortic valve replacement planning with renal insufficiency. Int J Cardiol. 2017 Mar 15; 231:255-257.
Zhu C, Tian B, Leach JR, Liu Q, Lu J, Chen L, Saloner D, Hope MD. Non-contrast 3D black blood MRI for abdominal aortic aneurysm surveillance: comparison with CT angiography. Eur Radiol. 2017 May; 27(5):1787-1794.
Ge L, Haraldsson H, Hope MD, Saloner D, Guccione JM, Ratcliffe MB, Tseng EE. Suture Forces for Closure of Transapical Transcatheter Aortic Valve Replacement: A Mathematical Model. J Heart Valve Dis. 2016 Jul; 25(4):424-429.
Ordovas KG, Keedy A, Naeger DM, Kallianos K, Foster E, Liu J, Saloner D, Hope MD. Dilatation of the ascending aorta is associated with presence of aortic regurgitation in patients after repair of tetralogy of Fallot. Int J Cardiovasc Imaging. 2016 Aug; 32(8):1265-72.
Burris NS, Dyverfeldt P, Hope MD. Ascending Aortic Stiffness with Bicuspid Aortic Valve is Variable and Not Predicted by Conventional Parameters in Young Patients. J Heart Valve Dis. 2016 May; 25(3):270-280.
Vasanawala SS, Nguyen KL, Hope MD, Bridges MD, Hope TA, Reeder SB, Bashir MR. Safety and technique of ferumoxytol administration for MRI. Magn Reson Med. 2016 May; 75(5):2107-11.
Wisneski AD, Mookhoek A, Chitsaz S, Hope MD, Guccione JM, Ge L, Tseng EE. Bicuspid Aortic Valve-Associated Ascending Thoracic Aortic Aneurysm: Patient-Specific Finite Element Analysis. J Heart Valve Dis. 2015 Nov; 24(6):714-721.
Conrad MB, Ishaque BM, Surman AM, Kerlan RK, Hope MD, Dickey MA, Hetts SW, Wilson MW. Intraprocedural Safety and Technical Success of the MVP Micro Vascular Plug for Embolization of Pulmonary Arteriovenous Malformations. J Vasc Interv Radiol. 2015 Nov; 26(11):1735-9.
Zhu C, Haraldsson H, Faraji F, Owens C, Gasper W, Ahn S, Liu J, Laub G, Hope MD, Saloner D. Isotropic 3D black blood MRI of abdominal aortic aneurysm wall and intraluminal thrombus. Magn Reson Imaging. 2016 Jan; 34(1):18-25.
Kathiria NN, Devcic Z, Chen JS, Naeger DM, Hope MD, Higgins CB, Ordovas KG. Assessment of Left Ventricular Enlargement at Multidetector Computed Tomography. J Comput Assist Tomogr. 2015 Sep-Oct; 39(5):794-6.
Dyverfeldt P, Bissell M, Barker AJ, Bolger AF, Carlhäll CJ, Ebbers T, Francios CJ, Frydrychowicz A, Geiger J, Giese D, Hope MD, Kilner PJ, Kozerke S, Myerson S, Neubauer S, Wieben O, Markl M. 4D flow cardiovascular magnetic resonance consensus statement. J Cardiovasc Magn Reson. 2015 Aug 10; 17:72.
Krishnan K, Ge L, Haraldsson H, Hope MD, Saloner DA, Guccione JM, Tseng EE. Ascending thoracic aortic aneurysm wall stress analysis using patient-specific finite element modeling of in vivo magnetic resonance imaging. Interact Cardiovasc Thorac Surg. 2015 Oct; 21(4):471-80.
Burris NS, Johnson KM, Larson PE, Hope MD, Nagle SK, Behr SC, Hope TA. Detection of Small Pulmonary Nodules with Ultrashort Echo Time Sequences in Oncology Patients by Using a PET/MR System. Radiology. 2016 Jan; 278(1):239-46.
Hope MD, Hope TA, Zhu C, Faraji F, Haraldsson H, Ordovas KG, Saloner D. Vascular Imaging With Ferumoxytol as a Contrast Agent. AJR Am J Roentgenol. 2015 Sep; 205(3):W366-73.
Hope MD, Gasper WJ, Rapp J, Owens CD, Haraldsson H, Saloner D. Vascular inflammation in a growing iliac artery aneurysm. Clin Nucl Med. 2015 Jun; 40(6):e323-4.
Sohrabi S, Hope M, Saloner D, Keedy A, Naeger D, Lorca MC, Ordovas KG. Left atrial transverse diameter on computed tomography angiography can accurately diagnose left atrial enlargement in patients with atrial fibrillation. J Thorac Imaging. 2015 May; 30(3):214-7.
Burris NS, Hope MD. Bicuspid valve-related aortic disease: flow assessment with conventional phase-contrast MRI. Acad Radiol. 2015 Jun; 22(6):690-6.
Sigovan M, Dyverfeldt P, Wrenn J, Tseng EE, Saloner D, Hope MD. Extended 3D approach for quantification of abnormal ascending aortic flow. Magn Reson Imaging. 2015 Jun; 33(5):695-700.
Kari FA, Kocher N, Beyersdorf F, Tscheuschler A, Meffert P, Rylski B, Siepe M, Russe MF, Hope MD. Four-dimensional magnetic resonance imaging-derived ascending aortic flow eccentricity and flow compression are linked to aneurysm morphology†. Interact Cardiovasc Thorac Surg. 2015 May; 20(5):582-7; discussion 587-8.
Benedetti N, Hope MD. Prevalence and significance of incidentally noted dilation of the ascending aorta on routine chest computed tomography in older patients. J Comput Assist Tomogr. 2015 Jan-Feb; 39(1):109-11.
Hope MD, Sigovan M, Dyverfeldt P. Letter by Hope et al regarding article, "Bicuspid aortic cusp fusion morphology alters aortic three-dimensional outflow patterns, wall shear stress, and expression of aortopathy". Circulation. 2014 Nov 04; 130(19):e170.
Wisneski AD, Mookhoek A, Chitsaz S, Hope MD, Guccione JM, Ge L, Tseng EE. Patient-specific finite element analysis of ascending thoracic aortic aneurysm. J Heart Valve Dis. 2014 Nov; 23(6):765-72.
Burris NS, Hope MD. 4D flow MRI applications for aortic disease. Magn Reson Imaging Clin N Am. 2015 Feb; 23(1):15-23.
Burris NS, Sigovan M, Knauer HA, Tseng EE, Saloner D, Hope MD. Systolic flow displacement correlates with future ascending aortic growth in patients with bicuspid aortic valves undergoing magnetic resonance surveillance. Invest Radiol. 2014 Oct; 49(10):635-9.
Velez E, Boyer N, Acevedo-Bolton G, Hope MD, Boyle A. CT-reconstructed three-dimensional printed models of the right subclavian artery and aorta define age-related changes and facilitate benchtop catheter testing. J Invasive Cardiol. 2014 Oct; 26(10):E141-4.
Dusch MN, Thadani SR, Dhillon GS, Hope MD. Diastolic function assessed by cardiac MRI using longitudinal left ventricular fractional shortening. Clin Imaging. 2014 Sep-Oct; 38(5):666-8.
Thadani SR, Dyverfeldt P, Gin A, Chitsaz S, Rao RK, Hope MD. Comprehensive evaluation of culture-negative endocarditis with use of cardiac and 4-dimensional-flow magnetic resonance imaging. Tex Heart Inst J. 2014 Jun; 41(3):351-2.
Liu J, Dyverfeldt P, Acevedo-Bolton G, Hope M, Saloner D. Highly accelerated aortic 4D flow MR imaging with variable-density random undersampling. Magn Reson Imaging. 2014 Oct; 32(8):1012-20.
Haraldsson H, Hope M, Acevedo-Bolton G, Tseng E, Zhong X, Epstein FH, Ge L, Saloner D. Feasibility of asymmetric stretch assessment in the ascending aortic wall with DENSE cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2014 Jan 09; 16:6.
Hope MD, Hope TA. Functional and molecular imaging techniques in aortic aneurysm disease. Curr Opin Cardiol. 2013 Nov; 28(6):609-18.
Hope MD, Sigovan M, Wrenn SJ, Saloner D, Dyverfeldt P. MRI hemodynamic markers of progressive bicuspid aortic valve-related aortic disease. J Magn Reson Imaging. 2014 Jul; 40(1):140-5.
Hope MD, Sedlic T, Dyverfeldt P. Cardiothoracic magnetic resonance flow imaging. J Thorac Imaging. 2013 Jul; 28(4):217-30.
Ordovas KG, Muzzarelli S, Hope MD, Naeger DM, Karl T, Reddy GP, Marchiori E, Higgins CB. Cardiovascular MR imaging after surgical correction of tetralogy of Fallot: approach based on understanding of surgical procedures. Radiographics. 2013 Jul-Aug; 33(4):1037-52.
Azadani AN, Chitsaz S, Mannion A, Mookhoek A, Wisneski A, Guccione JM, Hope MD, Ge L, Tseng EE. Biomechanical properties of human ascending thoracic aortic aneurysms. Ann Thorac Surg. 2013 Jul; 96(1):50-8.
Hope TA, Kvitting JP, Hope MD, Miller DC, Markl M, Herfkens RJ. Evaluation of Marfan patients status post valve-sparing aortic root replacement with 4D flow. Magn Reson Imaging. 2013 Nov; 31(9):1479-84.
Hope MD, Wrenn SJ, Dyverfeldt P. Clinical Applications of Aortic 4D Flow Imaging. Curr Cardiovasc Imaging Rep. 2013; 6(2):128-39.
Dyverfeldt P, Hope MD, Tseng EE, Saloner D. Magnetic resonance measurement of turbulent kinetic energy for the estimation of irreversible pressure loss in aortic stenosis. JACC Cardiovasc Imaging. 2013 Jan; 6(1):64-71.
Markl M, Frydrychowicz A, Kozerke S, Hope M, Wieben O. 4D flow MRI. J Magn Reson Imaging. 2012 Nov; 36(5):1015-36.
Lu MT, Thadani SR, Hope MD. Quantitative assessment of asymmetric aortic dilation with valve-related aortic disease. Acad Radiol. 2013 Jan; 20(1):10-5.
Hope MD, Wrenn J, Sigovan M, Foster E, Tseng EE, Saloner D. Imaging biomarkers of aortic disease: increased growth rates with eccentric systolic flow. J Am Coll Cardiol. 2012 Jul 24; 60(4):356-7.
Yildiz S, Boyaci N, Karakas O, Karakas E, Cece H. Re: bovine aortic arch: a novel association with thoracic aortic dilation. Clin Radiol. 2012 Jun; 67(6):618; author reply 618.
Cannavale G, Hope MD, Crook SE, Elicker BM. Dynamic evaluation of a quadricuspid aortic valve with coronary computed tomography angiography. J Thorac Imaging. 2012 May; 27(3):W46-7.
Chitsaz S, Gundiah N, Blackshear C, Tegegn N, Yan KS, Azadani AN, Hope M, Tseng EE. Correlation of calcification on excised aortic valves by micro-computed tomography with severity of aortic stenosis. J Heart Valve Dis. 2012 May; 21(3):320-7.
Mallik M, Callaghan CJ, Hope M, Gibbs P, Davies S, Gimson AE, Griffiths WJ, Pettigrew GJ. Comparison of liver transplantation outcomes from adult split liver and circulatory death donors. Br J Surg. 2012 Jun; 99(6):839-47.
Hope TA, Hope MD. Improved risk assessment for abdominal aortic aneurysm rupture: off-the-wall imaging. J Am Coll Cardiol. 2011 Dec 06; 58(24):2531-2.
Hope MD, Urbania TH, Yu JP, Chitsaz S, Tseng E. Incidental aortic valve calcification on CT scans: significance for bicuspid and tricuspid valve disease. Acad Radiol. 2012 May; 19(5):542-7.
Malone CD, Urbania TH, Crook SE, Hope MD. Bovine aortic arch: a novel association with thoracic aortic dilation. Clin Radiol. 2012 Jan; 67(1):28-31.
Ordovas KG, Carlsson M, Lease KE, Foster E, Meadows AK, Martin AJ, Hope M, Do L, Higgins CB, Saeed M. Impaired regional left ventricular strain after repair of tetralogy of Fallot. J Magn Reson Imaging. 2012 Jan; 35(1):79-85.
Sigovan M, Hope MD, Dyverfeldt P, Saloner D. Comparison of four-dimensional flow parameters for quantification of flow eccentricity in the ascending aorta. J Magn Reson Imaging. 2011 Nov; 34(5):1226-30.
Hope MD, Dyverfeldt P, Acevedo-Bolton G, Wrenn J, Foster E, Tseng E, Saloner D. Post-stenotic dilation: evaluation of ascending aortic dilation with 4D flow MR imaging. Int J Cardiol. 2012 Apr 19; 156(2):e40-2.
Muzzarelli S, Meadows AK, Ordovas KG, Hope MD, Higgins CB, Nielsen JC, Geva T, Meadows JJ. Prediction of hemodynamic severity of coarctation by magnetic resonance imaging. Am J Cardiol. 2011 Nov 01; 108(9):1335-40.
Hope MD, Hope TA, Crook SE, Ordovas KG, Urbania TH, Alley MT, Higgins CB. 4D flow CMR in assessment of valve-related ascending aortic disease. JACC Cardiovasc Imaging. 2011 Jul; 4(7):781-7.
Crook SE, Hope MD. Arch hypoplasia and aneurysm after aortic coarctation repair: abnormal flow may be the link. JACC Cardiovasc Imaging. 2011 Jun; 4(6):685-6.
Muzzarelli S, Ordovas KG, Hope MD, Meadows JJ, Higgins CB, Meadows AK. Diagnostic value of the flow profile in the distal descending aorta by phase-contrast magnetic resonance for predicting severe coarctation of the aorta. J Magn Reson Imaging. 2011 Jun; 33(6):1440-6.
Bogren HG, Buonocore MH. Helical-shaped streamlines do not represent helical flow. Radiology. 2010 Dec; 257(3):895-6; author reply 896.
Hope MD, Hope TA, Urbania TH, Higgins CB. Four-dimensional flow magnetic resonance imaging with wall shear stress analysis before and after repair of aortopulmonary fistula. Circ Cardiovasc Imaging. 2010 Nov; 3(6):766-8.
Girdauskas E, Borger MA, Kuntze T, Hope MD. Aortopathy in bicuspid aortic valve disease: is it really congenital? Radiology. 2010 Sep; 256(3):1015-6; author reply 1016.
Holmes CB, Coggin W, Jamieson D, Mihm H, Granich R, Savio P, Hope M, Ryan C, Moloney-Kitts M, Goosby EP, Dybul M. Use of generic antiretroviral agents and cost savings in PEPFAR treatment programs. JAMA. 2010 Jul 21; 304(3):313-20.
Hope MD, Hope TA, Meadows AK, Ordovas KG, Urbania TH, Alley MT, Higgins CB. Bicuspid aortic valve: four-dimensional MR evaluation of ascending aortic systolic flow patterns. Radiology. 2010 Apr; 255(1):53-61.
Hope MD, Meadows AK, Hope TA, Ordovas KG, Saloner D, Reddy GP, Alley MT, Higgins CB. Clinical evaluation of aortic coarctation with 4D flow MR imaging. J Magn Reson Imaging. 2010 Mar; 31(3):711-8.
Hope TA, Hope MD, Purcell DD, von Morze C, Vigneron DB, Alley MT, Dillon WP. Evaluation of intracranial stenoses and aneurysms with accelerated 4D flow. Magn Reson Imaging. 2010 Jan; 28(1):41-6.
Urbania TH, Hope MD, Huffaker SD, Reddy GP. Role of computed tomography in the evaluation of acute chest pain. J Cardiovasc Comput Tomogr. 2009 Jan-Feb; 3(1 Suppl):S13-22.
Hope MD, Purcell DD, Hope TA, von Morze C, Vigneron DB, Alley MT, Dillon WP. Complete intracranial arterial and venous blood flow evaluation with 4D flow MR imaging. AJNR Am J Neuroradiol. 2009 Feb; 30(2):362-6.
Hope MD, Meadows AK, Hope TA, Ordovas KG, Reddy GP, Alley MT, Higgins CB. Images in cardiovascular medicine. Evaluation of bicuspid aortic valve and aortic coarctation with 4D flow magnetic resonance imaging. Circulation. 2008 May 27; 117(21):2818-9.
Markl M, Draney MT, Hope MD, Levin JM, Chan FP, Alley MT, Pelc NJ, Herfkens RJ. Time-resolved 3-dimensional velocity mapping in the thoracic aorta: visualization of 3-directional blood flow patterns in healthy volunteers and patients. J Comput Assist Tomogr. 2004 Jul-Aug; 28(4):459-68.
Hope MD, Levin JM, Markl M, Draney MT, Alley M, Herfkens RJ. Images in cardiovascular medicine. Four-dimensional magnetic resonance velocity mapping in a healthy volunteer with pseudocoarctation of the thoracic aorta. Circulation. 2004 Jun 29; 109(25):3221-2.
Hope MD. Everyday amnesia. The curious effects of a common drug. Pharos Alpha Omega Alpha Honor Med Soc. 2004; 67(1):18-21.
Hope MD, de la Pena E, Yang PC, Liang DH, McConnell MV, Rosenthal DN. A visual approach for the accurate determination of echocardiographic left ventricular ejection fraction by medical students. J Am Soc Echocardiogr. 2003 Aug; 16(8):824-31.
Hope MD. MSJAMA. Pain and forgetting. JAMA. 2003 Feb 05; 289(5):617.
Pravenec M, Kren V, Hope M, Wang JM, St Lezin E. Linkage mapping of the interleukin 1beta converting enzyme (Il1bc) and the glutamate receptor subunit KA1 (Grik4) genes to rat chromosome 8. Folia Biol (Praha). 1998; 44(3):107-9.