Javier Villanueva-Meyer, MD

Assistant Professor
Asst.Professor Clin. Radiology


Javier Villanueva­Meyer, MD, is an Assistant Professor of Clinical Radiology in the Neuroradiology subspecialty section in the Department of Radiology and Biomedical Imaging at the University of California, San Francisco. He received his medical degree from Baylor College of Medicine in Houston, Texas, and he completed his one-year internship at Virginia Tech Carilion School of Medicine in Roanoke. Dr. Villanueva­Meyer completed his four-year diagnostic radiology residency at the UCSF, followed by a Neuroradiology fellowship at UCSF. He also completed a NIH T32 post-doctoral fellowship in the UCSF Department of Radiology and Biomedical Imaging.

Dr. Villanueva-Meyer’s interests focus on advanced MR imaging and imaging based tools to better delineate and characterize brain tumors. His research also involves molecular imaging where he works with collaborators within and outside of our department to develop and implement the use of PET radiotracers in both brain tumors and spinal infection.

Dr. Villanueva­Meyer has experience in CT, MRI and plain film radiography of the brain, head and neck, spine, and peripheral nervous system in both the inpatient and outpatient settings. As well as diagnostic and therapeutic neuroradiology procedures, including percutaneous biopsy, lumbar puncture, myelography, cisternography, epidural and selective nerve root injection.


Brain Tumor Radiology

Professional Interests:
MRI of brain tumors, imaging of infection, molecular imaging

Honors and Awards

Trainee Award, American Society of Neuroradiology, 2017
Elmer Ng MD Award for Outstanding Resident in Diagnostic Radiology, UCSF, 2016
Outstanding Podium Presentation, Imaging Research Symposium, 2016


Villanueva-Meyer JE, Mabray MC, Cha S. Current Clinical Brain Tumor Imaging. Neurosurgery. 2017 Sep 01; 81(3):397-415.
Lambert JW, Phillips ED, Villanueva-Meyer JE, Nardo L, Facchetti L, Gould RG. Axial or Helical? Considerations for wide collimation CT scanners capable of volumetric imaging in both modes. Med Phys. 2017 Aug 20.
Neumann KD, Villanueva-Meyer JE, Mutch CA, Flavell RR, Blecha JE, Kwak T, Sriram R, VanBrocklin HF, Rosenberg OS, Ohliger MA, Wilson DM. Imaging Active Infection in vivo Using D-Amino Acid Derived PET Radiotracers. Sci Rep. 2017 Aug 11; 7(1):7903.
Villanueva-Meyer JE, Han SJ, Cha S, Butowski NA. Early tumor growth between initial resection and radiotherapy of glioblastoma: incidence and impact on clinical outcomes. J Neurooncol. 2017 Aug; 134(1):213-219.
Ehman EC, Johnson GB, Villanueva-Meyer JE, Cha S, Leynes AP, Larson PE, Hope TA. PET/MRI: Where might it replace PET/CT? J Magn Reson Imaging. 2017 Mar 30.
Villanueva-Meyer JE, Barajas RF, Mabray MC, Chen W, Shankaranarayanan A, Koon P, Barani IJ, Tihan T, Cha S. Differentiation of brain tumor-related edema based on 3D T1rho imaging. Eur J Radiol. 2017 Jun; 91:88-92.
Aboian MS, Solomon DA, Felton E, Mabray MC, Villanueva-Meyer JE, Mueller S, Cha S. Imaging Characteristics of Pediatric Diffuse Midline Gliomas with Histone H3 K27M Mutation. AJNR Am J Neuroradiol. 2017 Apr; 38(4):795-800.
Mabray MC, Cohen BA, Villanueva-Meyer JE, Valles FE, Barajas RF, Rubenstein JL, Cha S. Performance of Apparent Diffusion Coefficient Values and Conventional MRI Features in Differentiating Tumefactive Demyelinating Lesions From Primary Brain Neoplasms. AJR Am J Roentgenol. 2015 Nov; 205(5):1075-85.
Mabray MC, Barajas RF, Villanueva-Meyer JE, Zhang CA, Valles FE, Rubenstein JL, Cha S. The Combined Performance of ADC, CSF CXC Chemokine Ligand 13, and CSF Interleukin 10 in the Diagnosis of Central Nervous System Lymphoma. AJNR Am J Neuroradiol. 2016 Jan; 37(1):74-9.
Villanueva-Meyer JE, Cha S. From Shades of Gray to Microbiologic Imaging: A Historical Review of Brain Abscess Imaging: RSNA Centennial Article. Radiographics. 2015 Sep-Oct; 35(5):1555-62.
Villanueva-Meyer J, Glastonbury C, Marcovici P. Congenital midline cervical cleft. J Radiol Case Rep. 2015 Mar; 9(3):7-11.
Phelps AS, Naeger DM, Courtier JL, Lambert JW, Marcovici PA, Villanueva-Meyer JE, MacKenzie JD. Pairwise comparison versus Likert scale for biomedical image assessment. AJR Am J Roentgenol. 2015 Jan; 204(1):8-14.
Bakken TE, Roddey JC, Djurovic S, Akshoomoff N, Amaral DG, Bloss CS, Casey BJ, Chang L, Ernst TM, Gruen JR, Jernigan TL, Kaufmann WE, Kenet T, Kennedy DN, Kuperman JM, Murray SS, Sowell ER, Rimol LM, Mattingsdal M, Melle I, Agartz I, Andreassen OA, Schork NJ, Dale AM, Weiner M, Aisen P, Petersen R, Jack CR, Jagust W, Trojanowki JQ, Toga AW, Beckett L, Green RC, Saykin AJ, Morris J, Liu E, Montine T, Gamst A, Thomas RG, Donohue M, Walter S, Gessert D, Sather T, Harvey D, Kornak J, Dale A, Bernstein M, Felmlee J, Fox N, Thompson P, Schuff N, Alexander G, DeCarli C, Bandy D, Koeppe RA, Foster N, Reiman EM, Chen K, Mathis C, Cairns NJ, Taylor-Reinwald L, Trojanowki JQ, Shaw L, Lee VM, Korecka M, Crawford K, Neu S, Foroud TM, Potkin S, Shen L, Kachaturian Z, Frank R, Snyder PJ, Molchan S, Kaye J, Quinn J, Lind B, Dolen S, Schneider LS, Pawluczyk S, Spann BM, Brewer J, Vanderswag H, Heidebrink JL, Lord JL, Johnson K, Doody RS, Villanueva-Meyer J, Chowdhury M, Stern Y, Honig LS, Bell KL, Morris JC, Ances B, Carroll M, Leon S, Mintun MA, Schneider S, Marson D, Griffith R, Clark D, Grossman H, Mitsis E, Romirowsky A, deToledo-Morrell L, Shah RC, Duara R, Varon D, Roberts P, Albert M, Onyike C, Kielb S, Rusinek H, de Leon MJ, Glodzik L, De Santi S, Doraiswamy PM, Petrella JR, Coleman RE, Arnold SE, Karlawish JH, Wolk D, Smith CD, Jicha G, Hardy P, Lopez OL, Oakley M, Simpson DM, Porsteinsson AP, Goldstein BS, Martin K, Makino KM, Ismail MS, Brand C, Mulnard RA, Thai G, Mc-Adams-Ortiz C, Womack K, Mathews D, Quiceno M, Diaz-Arrastia R, King R, Weiner M, Martin-Cook K, DeVous M, Levey AI, Lah JJ, Cellar JS, Burns JM, Anderson HS, Swerdlow RH, Apostolova L, Lu PH, Bartzokis G, Silverman DH, Graff-Radford NR, Parfitt F, Johnson H, Farlow MR, Hake AM, Matthews BR, Herring S, van Dyck CH, Carson RE, MacAvoy MG, Chertkow H, Bergman H, Hosein C, Black S, Stefanovic B, Caldwell C, Hsiung R, Feldman H, Mudge B, Assaly M, Kertesz A, Rogers J, Trost D, Bernick C, Munic D, Kerwin D, Mesulam MM, Lipowski K, Wu CK, Johnson N, Sadowsky C, Martinez W, Villena T, Turner RS, Johnson K, Reynolds B, Sperling RA, Johnson KA, Marshall G, Frey M, Yesavage J, Taylor JL, Lane B, Rosen A, Tinklenberg J, Sabbagh M, Belden C, Jacobson S, Kowall N, Killiany R, Budson AE, Norbash A, Johnson PL, Obisesan TO, Wolday S, Bwayo SK, Lerner A, Hudson L, Ogrocki P, Fletcher E, Carmichael O, Olichney J, Kittur S, Borrie M, Lee TY, Bartha R, Johnson S, Asthana S, Carlsson CM, Potkin SG, Preda A, Nguyen D, Tariot P, Fleisher A, Reeder S, Bates V, Capote H, Rainka M, Scharre DW, Kataki M, Zimmerman EA, Celmins D, Brown AD, Pearlson GD, Blank K, Anderson K, Santulli RB, Schwartz ES, Sink KM, Williamson JD, Garg P, Watkins F, Ott BR, Querfurth H, Tremont G, Salloway S, Malloy P, Correia S, Rosen HJ, Miller BL, Mintzer J, Longmire CF, Spicer K, Finger E, Rachinsky I, Drost D, Jernigan T, McCabe C, Grant E, Ernst T, Kuperman J, Chung Y, Murray S, Bloss C, Darst B, Pritchett L, Saito A, Amaral D, DiNino M, Eyngorina B, Sowell E, Houston S, Soderberg L, Kaufmann W, van Zijl P, Rizzo-Busack H, Javid M, Mehta N, Ruberry E, Powers A, Rosen B, Gebhard N, Manigan H, Frazier J, Kennedy D, Yakutis L, Hill M, Gruen J, Bosson-Heenan J, Carlson H. Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans. Proc Natl Acad Sci U S A. 2012 Mar 06; 109(10):3985-90.
Simoni J, Villanueva-Meyer J, Simoni G, Moeller JF, Wesson DE. Control of oxidative reactions of hemoglobin in the design of blood substitutes: role of the ascorbate-glutathione antioxidant system. Artif Organs. 2009 Feb; 33(2):115-26.
Khalkhali I, Baum JK, Villanueva-Meyer J, Edell SL, Hanelin LG, Lugo CE, Taillefer R, Freeman LM, Neal CE, Scheff AM, Connolly JL, Schnitt SJ, Houlihan MJ, Sampalis JS, Haber SB. (99m)Tc sestamibi breast imaging for the examination of patients with dense and fatty breasts: multicenter study. Radiology. 2002 Jan; 222(1):149-55.
Khalkhali I, Villanueva-Meyer J, Edell SL, Connolly JL, Schnitt SJ, Baum JK, Houlihan MJ, Jenkins RM, Haber SB. Diagnostic accuracy of 99mTc-sestamibi breast imaging: multicenter trial results. J Nucl Med. 2000 Dec; 41(12):1973-9.
Walser EM, DeLa Pena R, Villanueva-Meyer J, Ozkan O, Soloway R. Hepatic perfusion before and after the transjugular intrahepatic portosystemic shunt procedure: impact on survival. J Vasc Interv Radiol. 2000 Jul-Aug; 11(7):913-8.
De La Peña RC, Ketonen L, Villanueva-Meyer J. Imaging of brain tumors in AIDS patients by means of dual-isotope thallium-201 and technetium-99m sestamibi single-photon emission tomography. Eur J Nucl Med. 1998 Oct; 25(10):1404-11.
Ketonen L, De la Peña RC, Villanueva-Meyer J. MR and TL-210 spect imaging with pathologic correlation for the assessment of CNS lymphoma vs. toxoplasmosis in AIDS patients. J NeuroAIDS. 1998; 2(1):21-42.
Russell JM, Early TS, Patterson JC, Martin JL, Villanueva-Meyer J, McGee MD. Temporal lobe perfusion asymmetries in schizophrenia. J Nucl Med. 1997 Apr; 38(4):607-12.
Sabbagh MN, Lynn P, Jhingran S, Massman P, Villanueva-Meyer J, Olup J, Doody RS. Correlations between SPECT regional cerebral blood flow and psychometric testing in patients with Alzheimer's disease. J Neuropsychiatry Clin Neurosci. 1997; 9(1):68-74.
Villanueva-Meyer J, Swischuk LE, Cesani F, Ali SA, Briscoe E. Pediatric gastric emptying: value of right lateral and upright positioning. J Nucl Med. 1996 Aug; 37(8):1356-8.
Cesani F, Walser E, Briscoe EG, Villanueva-Meyer J. Renal hemorrhage detection with Tc-99m labeled erythrocytes in a patient with polycystic disease. Clin Nucl Med. 1996 Aug; 21(8):658-9.
Villanueva-Meyer J, Leonard MH, Briscoe E, Cesani F, Ali SA, Rhoden S, Hove M, Cowan D. Mammoscintigraphy with technetium-99m-sestamibi in suspected breast cancer. J Nucl Med. 1996 Jun; 37(6):926-30.
Cesani F, Villanueva-Meyer J. Intense myocardial and lung uptake of 99m-Tc-pyrophosphate using single photon emission computed tomography in a patient with end-stage renal disease and secondary hyperparathyroidism. Int Urol Nephrol. 1996; 28(4):569-74.
Patange V, Cesani F, Phillpott J, Villanueva-Meyer J. Three-phase bone and Ga-67 scintigraphy in disseminated sporotrichosis. Clin Nucl Med. 1995 Oct; 20(10):909-12.
Rubin RT, Ananth J, Villanueva-Meyer J, Trajmar PG, Mena I. Regional 133xenon cerebral blood flow and cerebral 99mTc-HMPAO uptake in patients with obsessive-compulsive disorder before and during treatment. Biol Psychiatry. 1995 Oct 01; 38(7):429-37.
Cesani F, Ernst R, Storey G, Villanueva-Meyer J. Multicentric meningioma evaluation with Tc-99m MIBI SPECT, CT, and MRI. Clin Nucl Med. 1995 Jun; 20(6):557-8.
Cesani F, Douzdjian V, Ali S, Villanueva-Meyer J. Renal scintigraphy of an infarction in an en bloc transplantation of a horseshoe kidney. Clin Nucl Med. 1995 May; 20(5):455-7.
Cesani F, Tee H, Esquivel-Avila J, Villanueva-Meyer J. Pericardial effusion in primary hypothyroidism. Tc-99m sestamibi imaging. Clin Nucl Med. 1995 May; 20(5):457-8.
Cesani F, Ernst R, Walser E, Villanueva-Meyer J. Tc-99m sestamibi imaging of a pancreatic VIPoma and parathyroid adenoma in a patient with multiple type I endocrine neoplasia. Clin Nucl Med. 1994 Jun; 19(6):532-4.
Mena I, Giombetti RJ, Miller BL, Garrett K, Villanueva-Meyer J, Mody C, Goldberg MA. Cerebral blood flow changes with acute cocaine intoxication: clinical correlations with SPECT, CT, and MRI. NIDA Res Monogr. 1994; 138:161-73.
Chang L, Anderson T, Migneco OA, Boone K, Mehringer CM, Villanueva-Meyer J, Berman N, Mena I. Cerebral abnormalities in myotonic dystrophy. Cerebral blood flow, magnetic resonance imaging, and neuropsychological tests. Arch Neurol. 1993 Sep; 50(9):917-23.
Engel P, Cummings JL, Villanueva-Meyer J, Mena I. Single photon emission computed tomography in dementia: relationship of perfusion to cognitive deficits. J Geriatr Psychiatry Neurol. 1993 Jul-Sep; 6(3):144-51.
Villanueva-Meyer J, Mena I, Diggles L, Narahara KA. Assessment of myocardial perfusion defect size after early and delayed SPECT imaging with technetium-99m-hexakis 2-methoxyisobutyl isonitrile after stress. J Nucl Med. 1993 Feb; 34(2):187-92.
Strickland TL, Mena I, Villanueva-Meyer J, Miller BL, Cummings J, Mehringer CM, Satz P, Myers H. Cerebral perfusion and neuropsychological consequences of chronic cocaine use. J Neuropsychiatry Clin Neurosci. 1993; 5(4):419-27.
Aquino S, Villanueva-Meyer J. Uptake of Tc-99m MDP in soft tissues related to radiographic contrast media extravasation. Clin Nucl Med. 1992 Dec; 17(12):974.
Calem-Grunat J, Sklar D, Villanueva-Meyer J, Mena I. Circumflex masquerade. Clin Nucl Med. 1992 Nov; 17(11):894.
Rubin RT, Villanueva-Meyer J, Ananth J, Trajmar PG, Mena I. Regional xenon 133 cerebral blood flow and cerebral technetium 99m HMPAO uptake in unmedicated patients with obsessive-compulsive disorder and matched normal control subjects. Determination by high-resolution single-photon emission computed tomography. Arch Gen Psychiatry. 1992 Sep; 49(9):695-702.
Geesaman B, Villanueva-Meyer J, Bluestein D, Miller L, Mena I, Rajfer J. Effects of multiple injections of HCG on testis blood flow. Urology. 1992 Jul; 40(1):81-3.
Villanueva-Meyer J, Mena I. Cerebral blood flow response to a mental activation task in early Alzheimer disease. Clin Neuropharmacol. 1992; 15 Suppl 1 Pt A:190A-191A.
Miller BL, Mena I, Giombetti R, Villanueva-Meyer J, Djenderedjian AH. Neuropsychiatric effects of cocaine: SPECT measurements. J Addict Dis. 1992; 11(4):47-58.
Di Lorenzo C, Reddy SN, Villanueva-Meyer J, Mena I, Martin S, Hyman PE. Cisapride in children with chronic intestinal pseudoobstruction. An acute, double-blind, crossover, placebo-controlled trial. Gastroenterology. 1991 Dec; 101(6):1564-70.
Reddy SN, Bazzocchi G, Chan S, Akashi K, Villanueva-Meyer J, Yanni G, Mena I, Snape WJ. Colonic motility and transit in health and ulcerative colitis. Gastroenterology. 1991 Nov; 101(5):1289-97.
Bazzocchi G, Ellis J, Villanueva-Meyer J, Reddy SN, Mena I, Snape WJ. Effect of eating on colonic motility and transit in patients with functional diarrhea. Simultaneous scintigraphic and manometric evaluations. Gastroenterology. 1991 Nov; 101(5):1298-306.
Miller BL, Cummings JL, Villanueva-Meyer J, Boone K, Mehringer CM, Lesser IM, Mena I. Frontal lobe degeneration: clinical, neuropsychological, and SPECT characteristics. Neurology. 1991 Sep; 41(9):1374-82.
Sullivan T, Villanueva-Meyer J, Liu CK, Giombetti R, Mena I. Watershed infarcts, Tc-99m HMPAO SPECT and CT correlation. Case reports. Clin Nucl Med. 1991 Mar; 16(3):170-3.
Narahara KA, Villanueva-Meyer J, Thompson CJ, Brizendine M, Mena I. Comparison of thallium-201 and technetium-99m hexakis 2-methoxyisobutyl isonitrile single-photon emission computed tomography for estimating the extent of myocardial ischemia and infarction in coronary artery disease. Am J Cardiol. 1990 Dec 15; 66(20):1438-44.
Pascual JA, Villanueva-Meyer J, Rutgers JL, Lemmi CA, Sikka SC, Ehrlich RM, Mena I, Rajfer J. Long-term effects of prepubertal testicular vessel ligation on testicular function in the rat. J Urol. 1990 Aug; 144(2 Pt 2):466-8; discussion 474.
Villanueva-Meyer J, Thompson D, Mena I, Marcus CS. Lacrimal gland dosimetry for the brain imaging agent technetium-99m-HMPAO. J Nucl Med. 1990 Jul; 31(7):1237-9.
Villanueva-Meyer J, Mena I, Narahara KA. Simultaneous assessment of left ventricular wall motion and myocardial perfusion with technetium-99m-methoxy isobutyl isonitrile at stress and rest in patients with angina: comparison with thallium-201 SPECT. J Nucl Med. 1990 Apr; 31(4):457-63.
Bazzocchi G, Ellis J, Villanueva-Meyer J, Jing J, Reddy SN, Mena I, Snape WJ. Postprandial colonic transit and motor activity in chronic constipation. Gastroenterology. 1990 Mar; 98(3):686-93.
Villanueva-Meyer J. Penile blood flow by xenon-133 washout. J Nucl Med. 1990 Feb; 31(2):246-7.
Pascual JA, Villanueva-Meyer J, Salido E, Ehrlich RM, Mena I, Rajfer J. Recovery of testicular blood flow following ligation of testicular vessels. J Urol. 1989 Aug; 142(2 Pt 2):549-52; discussion 572.
Moreno-Osset E, Bazzocchi G, Lo S, Trombley B, Ristow E, Reddy SN, Villanueva-Meyer J, Fain JW, Jing J, Mena I. Association between postprandial changes in colonic intraluminal pressure and transit. Gastroenterology. 1989 May; 96(5 Pt 1):1265-73.
Villanueva-Meyer J, Philippe L, Cordero S, Marcus CS, Mena I. Use of factor analysis in the evaluation of left to right cardiac shunts. J Nucl Med. 1986 Sep; 27(9):1442-8.
Villanueva-Meyer J, Marcus C, Thompson K, Philippe L, Mena I. Diagnosis and quantitation of pulmonary arteriovenous malformations by factor analysis. Clin Nucl Med. 1986 Feb; 11(2):88-91.