Research Stories

We serve a diverse range of individuals. One thing that many of them have in common is a willingness to share their stories. They do this because they know how hard it was to find a practice like ours and because of our commitment to them.

Department of Radiology and Biomedical Imaging

Sharmila Majumdar, PhD in the Department of Radiology and Biomedical Imaging

“Lower back pain is chronic today across all age groups. There are no established therapies, in part because there isn’t a clear understanding of the tissues contributing to the pain. Our goal is not to just develop markers, but develop objective measures of pain.” Learn more

 

John MacKenzie, MD in the department of Radiology and Biomedical Imaging

“Accurate diagnosis is extremely important in juvenile arthritis, as is using the lowest radiation exposure. PET/MRI research represents the next generation of imaging that will help us understand the disease and precisely identify the activity of a child's immune system.” Learn more

 

Mike Evans, MD in the Department of Radiology and Biomedical Imaging

“We think one of the reasons patients develop resistance to standard care therapy is because of an expression of a certain protein. Our imaging test is designed to detect this. We focus on seeing a subtype of a disease we know to be troublesome, not just focus on the presence or absence of disease. It’s a huge paradigm shift in the imaging field.” Learn more

 

Daniel Vigneron, MD in the Department of Radiology and Biomedical Imaging

“Hyperpolarized MRI allows us to pinpoint cancers that could not be detected very well anatomically, and monitor their rate of progression. We can also learn if therapies have hit their target and measure quantitatively whether they did what was intended.” Learn more

 

Michael Weiner, MD in the Department of Radiology and Biomedical Imaging

“The Alzheimer’s Disease Neuroimaging Initiative (ADNI) has been the major study to help validate new biomarkers for the identification of Alzheimer’s. All clinical trials today use these indicators to diagnose Alzheimer’s and move toward treatments to prevent or slow the progression of this debilitating disease.” Learn more

 

Mike Evans, MD in the Department of Radiology and Biomedical Imaging

“Biopsy may miss the general features of the patient’s disease. Every metastatic lesion may look different, but our imaging tools can pick this up. You never actually have to go near a scalpel. We’re doing noninvasive imaging that we can repeat, and we can monitor disease as it changes over time.” 

 

Matthew Bucknor, MD in the Department of Radiology and Biomedical Imaging

“HIFU, high intensity focused ultrasound, is an important new treatment option for patients with certain musculoskeletal tumors. It has significantly fewer inherent toxicities and risks than many standard therapies. We don’t make an incision, there are no significant systemic effects like with certain chemotherapeutic agents, and ultrasound uses no ionizing radiation.”  Learn more

 

Mike Evans, MD in the Department of Radiology and Biomedical Imaging

“When it comes to drug development, understanding the extent to which drugs are inhibiting their target is critically important. It is a difficult challenge, but needs our attention. How hard we’re hitting the target and its impact on standard care could mean everything.”

 

Enrique Menendez, MD and administrative manager in the Department of Radiology and Biomedical Imaging

“Radiology at UCSF is very unique, because it’s a clinical department. We provide a service: Interpreting radiologic images for patients in our clinics and hospitals. But there is also a significant amount of research by world-renown PhDs and MDs. And those researchers also do clinical work.” Learn more