2016 Accomplishments

Abdominal Imaging

  • Initiated an MRI elastography program to evaluate patients for liver fibrosis and fat content.
  • Increased substantially the volume of clinical prostate MRIs done at UCSF with the use of MR/US fusion software for biopsy targeting.  
  • Expanded PET/MRI program for body imaging with new novel radiotracers for prostate and neuroendocrine cancers.
  • Expanded the multidisciplinary renal tumor board. 
  • Expanded CT-guided percutaneous kidney tumor ablation program.
  • Expanded human research using hyperpolarized carbon 13 for pancreatic, renal, prostate and liver MR imaging.

Breast Imaging

  • Published a paper in the American Journal of Roentgenology in October 2016 titled “Improving Screening Mammography Outcomes Through Comparison With Multiple Prior Mammograms.” The research found that comparison with two or more prior mammograms at screening resulted in a statistically significant reduction in the recall rate and increase in cancer detection rate (CDR) and positive predictive value of recall (PPV1) relative to comparison with a single prior mammogram. This finding impacts clinical practice because many centers default to comparison with only one prior mammogram. Our study suggests that radiologists improve their diagnostic accuracy when comparing with more than one prior examination at screening mammography. 
  • The Avon Breast Center at Zuckerberg San Francisco General Hospital sponsored two Avon Scholars for the month of May 2016. The program is funded by the Avon Breast Cancer Crusade. Dr. Ana Clara Miranda is from Brazil, where she works in an Avon-funded screening center. Dr. Vladimir Urban of Belgrade also works in breast imaging. Both were interested in learning biopsy techniques as well as basic and advanced imaging. In addition to the clinical experience they received, they were able to shadow specialties like MRI, tomosynthesis, tomosynthesis-guided biopsies, breast ultrasounds, and stereotactic core biopsies.
  • The Avon Breast Center's mobile mammography van volume doubled since 2012. Eighty three (83%) of mammovan patients are minorities.  
  • Among African American women who receive their screening through ZSFG/Avon, 25% are screened on the van. By improving access to screening among traditionally harder to reach populations, the van can help address disparities in cancer outcomes.  


Fetal MRI of complicated twin pregnancy performed by Dr. Glenn of UCSF Imaging to assess the brain of one of the twins.

Pediatric Imaging

State-of-the-Art Computed Tomography

  • Parents say they choose UCSF (and have switched insurance plans) to have their children scanned with these low-dose techniques.
  • Better visualization of children's smaller anatomy at a lower dose translates to better, more confident interpretations on small patients with lower radiation dose, not available elsewhere.
  • This low-dose technique for image-guided biopsies translates to lower doses to vulnerable patients and more accurate biopsies.
  • Advanced image CT reconstruction translates to lower doses for infants, the most vulnerable patients.

Advanced Magnetic Resonance Imaging

  • Reduced need for anesthesia.
  • Improved patient and family experience.
  • High-resolution fast imaging of children’s small anatomy.

Specialized Imaged-Guided Procedures

  • Minimally invasive procedures reduce recovery time and the need for surgery or systemic medicine.

Musculoskeletal Imaging

  • MR-guided, high-intensity focused ultrasound (HIFU) for bone metastases, osteoid osteomas, and desmoid tumors established as clinical procedures. 
  • Established whole-body, low-dose CT for imaging of multiple myeloma improving patient comfort by reducing examination time from ~one hour for a skeletal survey (previous standard of care) to a few minutes. 
  • Established dual-energy CT for noninvasive imaging of gout, improving diagnosis and patient management.
  • Magnetic resonance zero-echo time imaging to provide CT-like images to our clinicians, reducing radiation exposure and allowing "one-stop-shopping” for patients.
  • Established loaded/stress MRI for imaging of the shoulder joint to better assess labral abnormalities.
  • Minimally invasive treatment of bone lesions by injecting drugs into aneurysmal bone cysts and eosinophilic granulomas.
  • Ultrasound and fluoroscopy-guided joint interventions for pain control and osteoarthritis treatment.
  • Use of MRI-based cartilage matrix measurements to characterize cartilage quality and predict risk of osteoarthritis.
  • Adding texture analysis to bone densitometry to improve fracture prediction in patients with bone loss in clinical routine.

2015 Accomplishments

Abdominal Imaging

Abdominal Imaging

  • Transitioned multiparametric prostate MRI examinations from a research tool to a clinical exam on clinical scanners.  
  • Translated our basic research achievements into clinical care with the most advanced MRI and post-processing techniques, most of which were developed here at UCSF.
  • Expanded CT-guided percutaneous kidney tumor ablation program
  • More cases
  • More referrals from urologists from outside the UCSF system
  • Expanded renal ablation and surgery tumor board.
  • Revised image guided biopsy request system for improved user interface with much greater ease for referring providers 

Breast Imaging

Breast Imaging

  • Expanded abscess drainage service, allowing us to help several patients with Serial drainages.
  • Mammi PETPET/MR
  • Expansion of same day clinic
  • Biopsy kits redesign (to reduce waste, increase)
  • Tomosynthesis
  • Additional faculty (increased FTE) dedicated to breast imaging to allow improved access for referring clinicians and patients to expert breast imaging consultations

Interventional Radiology

Interventional Imaging

  • Development of a service using the Angiovac device to remove thrombus fro, the systemic venous circulation
  • Development of a service to manage lymphatic leaks
  • Participation in a multi center trial to evaluate high-intensity focused ultrasound to treat uterine fibroids
  • Prospective evaluation of doxorubicin beads to treat hepatocellular carcinoma in patients with impaired liver function

Musculoskeletal Radiology

Musculoskeletal Imaging

  • MR-guided, high intensity focused ultrasound (HIFU) for bone metastasis, osteoid osteomas, and desmoid tumors.
  • Performed the second MR-guilded, HIFU osteoid osteoma treatment in the country.
  • Minimally invasive treatment of bone lesions by injecting drugs into aneurysmal bone cysts and eosinophilic granulomas.
  • Tissue harvesting for prostate cancer lesions to optimize personalized cancer therapy in conjunction with the Dream Team Study, Principal Investigator, Dr. Eric Small.
  • Ultrasound and fluoroscopy-guided joint interventions for pain control and osteoarthritis treatment.
  • Use of MRI-based cartilage matrix measurements to characterize cartilage quality and predict risk of osteoarthritis.
  • Use fat quantification of the rotator cuff muscles and of the spine muscles to predict outcome of shoulder surgery  and spine intervention.

Neuro Interventional Radiology

Neuro Interventional Radiology

  • Opened comprehensive NIR service at Mission Bay
  • BVAC moved to MB
  • HHT Clinic certified as one of only 19 Centers of Excellence in North America
  • UCSF and SFGH recertified as primary stroke centers
  • Pulsatile Tinnitus Clinic opened at Parnassus

Pediatric Radiology

Pediatric Radiology

  1. State-of-the-Art Computed Tomography
    • Parents choose UCSF (and have switched insurance plans) to have their children scanned with our low-dose techniques.
    • Better visualization of kid’s smaller anatomy at a lower dose - translates to better more confident interpretations on small patients with lower radiation dose, not available elsewhere.
    • Low dose technique for image guided biopsies - translates to lower doses to vulnerable patients and more accurate biopsies.
    • Advanced image CT reconstruction - translates to lower doses for infants, our most vulnerable patients.
  2. Advanced Magnetic Resonance Imaging
    • Reduced the need for anesthesia.
    • Improved patient and family experience.
    • High resolution fast imaging of children’s small anatomy
  3. Specialized Imaged Guided Procedures
    • Minimally invasive procedures reduce recovery time and the need for surgery or systemic medicine.